1. Extracorporeal membrane oxygenation for coronavirus disease 2019-associated acute respiratory distress syndrome: Report of two cases and review of the literature
- Author
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Wei-Yan Soh, Xiaozu Liao, Junlin Wen, Jian-Wei Li, Yong Yuan, Wen-Jun Gao, Qi-Zhe Sun, Wei-Jia Wang, Binfei Li, Liqiang Wang, Zhou Cheng, Liu-sheng Hou, and Daqing Ma
- Subjects
2019-20 coronavirus outbreak ,Complications ,Coronavirus disease 2019 (COVID-19) ,medicine.medical_treatment ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,Disease ,Acute respiratory distress ,medicine.disease_cause ,03 medical and health sciences ,0302 clinical medicine ,Case report ,medicine ,Extracorporeal membrane oxygenation ,Coronavirus ,Acute respiratory distress syndrome ,business.industry ,SARS-CoV-2 ,COVID-19 ,General Medicine ,Virology ,surgical procedures, operative ,030220 oncology & carcinogenesis ,030211 gastroenterology & hepatology ,business - Abstract
BACKGROUND Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus-2, is a worldwide pandemic. Some COVID-19 patients develop severe acute respiratory distress syndrome and progress to respiratory failure. In such cases, extracorporeal membrane oxygenation (ECMO) treatment is a necessary life-saving procedure. CASE SUMMARY Two special COVID-19 cases—one full-term pregnant woman and one elderly (72-year-old) man—were treated by veno-venous (VV)-ECMO in the Second People’s Hospital of Zhongshan, Zhongshan City, Guangdong Province, China. Both patients had developed refractory hypoxemia shortly after hospital admission, despite conventional support, and were therefore managed by VV-ECMO. Although both experienced multiple ECMO-related complications on top of the COVID-19 disease, their conditions improved gradually. Both patients were weaned successfully from the ECMO therapy. At the time of writing of this report, the woman has recovered completely and been discharged from hospital to home; the man remains on mechanical ventilation, due to respiratory muscle weakness and suspected lung fibrosis. As ECMO itself is associated with various complications, it is very important to understand and treat these complications to achieve optimal outcome. CONCLUSION VV-ECMO can provide sufficient gas exchange for COVID-19 patients with acute respiratory distress syndrome. However, it is crucial to understand and treat ECMO-related complications.
- Published
- 2021