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Objective: To evaluate retrospectively the relationship between low back pain and changes of lumbar spine sagittal alignment after lumbar spine fusion., Methods: During January-December 2008, a total of 182 consecutive patients with degenerative lumbar spine diseases underwent posterior lumbar interbody fusion (PLIF) and the follow-up period was over 24 months. Standing lumbar spine anteroposterior and lateral radiography were taken during the follow-up and the lumbar lordosis Cobb angles were measured on radiography. Pain degrees were assessed by visual analog scale (VAS) and Oswestry disability index (ODI). The relationship between the changes of Cobb angle and lumbar sagittal plane curve was analyzed by the SPSS software. Also the relationship between back pain degree and Cobb angle was examined., Results: Among them, 42 cases with postoperative back pain were followed up for 24 months. There were 19 males and 23 females with a mean age of 59.6 years (range: 40 - 77). Lumbar spine sagittal Cobb angles were measured from radiographic images:lumbar lordosis angle: (1) mean angle at 12-month follow-up: 40.1° ± 10.6°, range: 20° - 60°; (2) mean angle at 24-month follow-up: 40.8° ± 10°, range: 24° - 60°. Back pain of 42 patients: VAS: (1) mean at 12-month follow-up: 29.4 ± 11.5, range: 5 - 50; (2) mean at 24-month follow-up: 27.6 ± 11.7, range: 25 - 48. Lumbar spine function of 42 patients: ODI: (1) mean at 12-month follow-up: 15.1 ± 5.4, range: 0 - 25; (2) mean at 24-month follow-up: 13.9 ± 5.2, range: 0 - 24. Difference between lumbar lordosis angle and standard score: (1) mean angle at 12-month follow-up: 19.9° ± 10.6°, range:0°-40°; (2) mean angle at 24-month follow-up:19.2° ± 10.0°, range:0°-36°. Angle difference versus back pain VAS: (1) at 12-month follow-up:P < 0.001, positive correlation; (2) 24-month follow-up: P < 0.001, positive correlation; angle difference versus back pain ODI: (1) 12-month follow-up:P < 0.001, positive correlation; (2) 24-month follow-up: P < 0.001, positive correlation., Conclusion: There is a close relationship between back pain after fusion and loss of lumbar sagittal lordosis. And reconstruction of lumbar lordosis should be one important goal for lumbar fusion.

Objective: To evaluate the efficacy and safety of kyphoplasty for treatment of non-osteoporotic compressive fractures of thoracolumbar vertebrae., Methods: Seven patients of non-osteoporotic thoracolumbar compressive fractures confirmed by plain X-ray examination and CT scanning, 14 males and 3 females, aged 35.2, all suffering from one level fracture, at T9 in 1 case, T11 in 2 cases, T12 in 7 cases, L1 in 5 cases, L2 in 1 case, and L3 in 1 case were. treated with percutaneous kyphoplasty. Under local anesthesia Kypho-X vertebra expander was inserted into the vertebral body and polymethylmethacrylate (PMMA) bone cement was filled. Then the patients were followed up for 6 months (6-24 months) by using the visual analog scale, Oswestry disability index (ODI), and the vertebra height and kyphosis were analyzed., Results: All patients underwent the procedure safely. Except for two cases with complication of para-vertebra cement leakage no other complication occurred. The average surgery time was 55 min. All patients became able to get up of bed 2 days and discharged 7 days postoperatively and continued to be protected by hard prosthesis for two weeks more. The average score of VAS was 8.7 before the operation, and then gradually decreased, to 3.2 and 2.7 1 and 4 weeks postoperatively, and became 2.1 at the last follow-up (all P < 0.05). The average ODI score was 72.3 before the operation, and then gradually decreased to 48.6 and 28.9 1 week and 4 weeks postoperatively, and became 22.4 at the last follow-up (all P < 0.05). The average height of the vertebra was 14.3 mm preoperatively, and increased to 24.7 mm 1 week postoperative and 22.4 mm at the last follow up (both P < 0.05). The kyphosis of the fractured vertebra was 31.1 degrees preoperatively and decreased to 9.6 degrees 1 week postoperatively and 10.9 degrees at the last follow up (both P < 0.05). All patients returned to their previous work and life within 2 months postoperatively., Conclusion: Percutaneous kyphoplasty is effective and safe in the treatment of non-osteoporotic thoracolumbar compressive fractures with the advantages of minimum invasiveness, fast pain relief and recovery, as well as restoration of vertebra height and correction of kyphosis.