Search

Objective To evaluate the caries preventive effect and economic outcome of an oral health promotion model in rural primary schools in Guangxi Zhuang Autonomous Region. Methods In November 2015, a baseline survey was conducted on the caries prevalence of rural first graders in program areas, and then a program intervention was carried out on the first graders of target primary schools. The intervention methods included the distribution of oral health care products, oral health education, teacher training, etc. In 2020, the method of cluster random sampling was adopted to include the sixth graders who received the program intervention as first graders and were still available in 2020 as the intervention group. During this period, the sixth graders transferred from foreign schools who failed to receive the program intervention as first graders were included in the non-intervention group. The caries preventive effect was evaluated by analyzing the caries epidemiological data of 2 652 children aged 11-13 years, comparing the intervention and non-intervention group. The cost of the program was estimated by the structural analysis method. A decision tree model was established by TreeAge pro2019 and incorporated into the effect parameters and cost parameters for cost-effectiveness analysis and sensitivity analysis. Results The prevalence of caries in the intervention group was 54.8%, and the mean DMFT was 1.36 ± 1.64, both of which were lower than those in the non-intervention group. The difference in prevalence and mean DMFT between the two groups was statistically significant (P < 0.05). It costs CNY 319.83 per child to reduce suffering from caries. The number of patients with caries in the intervention group was the most sensitive indicator of an economic effect. The probability of a cost-effectiveness advantage for the program was 92.2%. Conclusion This oral health promotion model used in rural schools demonstrated a caries preventive effect that was very likely economically advantageous. It is of practical significance to improve and promote this model in the Guangxi Zhuang Autonomous Region.

Diabetic foot disease is a common and serious complication for diabetes and is characterized with impaired angiogenesis. Nurses are the primary providers of prevention and early diagnosis of diabetes and its complications. This paper summarized the role of clinical nurse specialist in prevention of diabetic foot disease, diabetic foot care and prevention of diabetic foot wounds. In terms of nursing, nurses are responsible for the observation of change in foot soft tissue and skin sensitivity, as well as foot care, dressing and use of the new technologies. In terms of rehabilitation, clinical nurse specialist are responsible for the exercise guidance and health education for patients with foot ulcer and amputated limbs (糖尿病足是糖尿病常见并发症之一, 护士是积极参与预防和早期发现糖尿病及其并发症的卫生保健提供者。本文概述了护士, 尤其是糖尿病专科护士, 在糖尿病足预防和护理中重要作用。在护理方面, 护士负责早期发现皮肤和足部感觉的变化, 开展足部护理、敷料和新技术的应用; 在康复领域, 糖尿病专科护士负责指导和帮助糖尿病足溃疡或截肢患者进行活动。)

Background: The psychosocial impact of dental aesthetics (PIDA) has a significant effect on well-being and quality of life. This study aimed to explore the latent heterogeneous classes of the PIDA among adolescents and investigate the relationships among identified subtypes and sociodemographic variables, the status of left-behind children, and the clinical manifestations of malocclusion. Methods: A cross-sectional study on the PIDA among 1451 adolescents aged 11 to 12 years in elementary schools in a rural area in Guangxi, China, was conducted. The PIDA on adolescents was also investigated via latent profile analysis; each predictor was tested via ordinal logistic regression. Results: Three latent classes for the PIDA were identified: low-risk (48.2%), medium-risk (39.8%), and high-risk (11.9%) groups. There were significant differences among the three latent classes. The results revealed that being female, The duration of maternal employment outside the hometown, the largest anterior maxillary irregularity, the largest anterior mandibular irregularity, and the antero-posterior molar relationship (ORs of 1.737, 1.138, 1.117, 1.157, and OR = 1.242; P < 0.001, < 0.01, < 0.01, < 0.01 and < 0.05, respectively) had significant effects on the PIDA on adolescents. Conclusions: The occlusal features, being female and the duration of maternal employment outside the hometown are risk factors that influence the PIDA on adolescents. This provides an evidence for improving the PIDA status among rural adolescents. [ABSTRACT FROM AUTHOR]

While it is well known that plants interpret UV-B as an environmental cue and a potential stressor influencing their growth and development, the specific effects of UV-B-induced oxidative stress on the dynamics of membrane lipids and proteins remain underexplored. Here, we demonstrate that UV-B exposure notably increases the formation of ordered lipid domains on the plasma membrane (PM) and significantly alters the behavior of the Glycine max nodule autoregulation receptor kinase (GmNARK) protein in Arabidopsis leaves. The GmNARK protein was located on the PM and accumulated as small particles in the cytoplasm. We found that UV-B irradiation interrupted the lateral diffusion of GmNARK proteins on the PM. Furthermore, UV-B light decreases the efficiency of surface molecule internalization by clathrin-mediated endocytosis (CME). In brief, UV-B irradiation increased the proportion of the ordered lipid phase and disrupted clathrin-dependent endocytosis; thus, the endocytic trafficking and lateral mobility of GmNARK protein on the plasma membrane are crucial for nodule formation tuning. Our results revealed a novel role of low-intensity UV-B stress in altering the organization of the plasma membrane and the dynamics of membrane-associated proteins. [ABSTRACT FROM AUTHOR]

Objective To assess family environmental factors that impact caries in children during a follow ⁃ up study for family⁃based community oral health promotion models. Methods This study was conducted from June to De⁃ cember 2015. A total of 200 households were selected from Jinzhou community in Nanning with the random sampling method. The data were collected through oral examinations and questionnaire surveys of family members. A logistic re⁃ gression model was used to analyze the relationship between family environment factors, such as socioeconomic and fam⁃ ily⁃related behaviors, and caries in children. Results After adjustment for confounding factors, families in which more than 1, 000 mL of sugar drinks were purchased per month; those in which the family members had a low frequency of brushing (occasionally or not); those in which the mother had a high frequency of drinking sweet drinks (more than one time each day), brushed with low frequency (less than 2 times), had no regular oral examination in the past year, or had low scores in oral health attitude and knowledge; those in which the father/mother had a low level of education (short⁃cy⁃ cle courses and under); and those with a low annual household income (less than 50, 000 RMB) had children with high rates of dental caries. Families purchasing sugar drinks >1 000 mL per month were 2.22 times more likely than families purchasing sugar drinks ≤1 000 mL per month to have caries in children. Conclusion Family environmental factors exert a certain influence on children􀆳s caries, and this information is a useful reference for a follow⁃up study.

Objectives: To assess the prevalence of caries and impaired glucose regulation (IGR) and try to investigate their common risk factors among adult residents in Guangxi province. Methods: A cross‐sectional study was conducted on a sample of 2993 adults from five different areas of Guangxi province. The sociodemographic data, history of personal habits such as diet and physical activities, physical measurements, oral examination results and biochemical laboratory test data were collected to establish a database and prepare a sound research model. Chi‐square test and multiple logistic regression were used to analyse the risk factors for dental caries and IGR. Results: The prevalence rate for caries was 85.9%, and the mean DMFT score was 7.35. In multiple logistic regression, after adjustment, education level, occupation, daily consumption of vegetables, weekly consumption of carbonated beverages and weekly exercise were associated with caries (odds ratio [OR]: 2.10, OR: 1.80, OR: 1.40, OR: 2.45, OR: 2.38). The prevalence of IGR was 33.5%, and after adjustment, results showed that occupation, body mass index, waist circumference, systolic blood pressure, diastolic blood pressure, high‐density lipoprotein‐C levels and low‐density lipoprotein‐C levels were significantly associated with IGR (OR: 0.80, OR: 1.70, OR: 1.56, OR: 1.88, OR: 1.60, OR: 1.43, OR: 1.48). The strength of association between caries/IGR and risk factors was a weak association or moderate association. Conclusions: We have not found common risk factors between dental caries and IGR. Therefore, further studies are needed to explore these common risk factors to prevent caries and IGR. [ABSTRACT FROM AUTHOR]

Summary: Legume nodulation requires light perception by plant shoots and precise long‐distance communication between shoot and root. Recent studies have revealed that TGACG‐motif binding factors (GmSTFs) integrate light signals to promote root nodulation; however, the regulatory mechanisms underlying nodule formation in changing light conditions remain elusive.Here, we applied genetic engineering, metabolite measurement, and transcriptional analysis to study soybean (Glycine max) nodules.We clarify a fine‐tuning mechanism in response to ultraviolet B (UV‐B) irradiation and rhizobia infection, involving GmUVR8‐dependent UV‐B perception and GmSTF3/4‐GmMYB12‐GmCHS‐mediated (iso)flavonoid biosynthesis for soybean nodule formation. GmUVR8 receptor‐perceived UV‐B signal triggered R2R3‐MYB transcription factors GmMYB12‐dependent flavonoid biosynthesis separately in shoot and root. In shoot, UV‐B‐triggered flavonoid biosynthesis relied on GmUVR8a, b, c receptor‐dependent activation of GmMYB12L‐GmCHS8 (chalcone synthase) module. In root, UV‐B signaling distinctly promotes the accumulation of the isoflavones, daidzein, and its derivative coumestrol, via GmMYB12B2‐GmCHS9 module, resulting in hypernodulation. The mobile transcription factors, GmSTF3/4, bind to cis‐regulatory elements in the GmMYB12L, GmMYB12B2, and GmCHS9 promoters, to coordinate UV‐B light perception in shoot and (iso)flavonoid biosynthesis in root.Our findings establish a novel shoot‐to‐root communication module involved in soybean nodulation and reveal an adaptive strategy employed by soybean roots in response to UV‐B light. [ABSTRACT FROM AUTHOR]

Due to the rapid economic development in recent years, the original transformers and other power supply equipment is difficult to meet the demand of the rapid growth of electricity consumption. In order to reduce the cost of power supply, adding photovoltaic/wind power/energy storage system is an effective means to meet the demand of users to achieve regional balance without the overall reform of the system. In this paper, with reference to Ganzhou region under different growth rate of electricity a internal power supply area, considering the three-phase imbalance and photovoltaic (pv) power supply under different weather factors efficiency under different conditions, building composed of piconets and time division at micro network life period earnings are applied to solve the highest net present value as the goal on the premise of micro power grid planning for the next step, meet the increasing social demand of power supply area, improve power supply reliability, provide strong theoretical support. Finally, based on the power supply load of a certain region in Ganzhou, the method is calculated and proved to be effective.