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37 results on '"Liu, P.W."'

5. Review of influenza-associated pulmonary aspergillosis in ICU patients and proposal for a case definition: an expert opinion

Author

Verweij, P.E., Rijnders, BJA, Brüggemann, RJM, Azoulay, E., Bassetti, M., Blot, S., Calandra, T., Clancy, C.J., Cornely, O.A., Chiller, T., Depuydt, P., Giacobbe, D.R., Janssen, NAF, Kullberg, B.J., Lagrou, K., Lass-Flörl, C., Lewis, R.E., Liu, P.W., Lortholary, O., Maertens, J., Martin-Loeches, I., Nguyen, M.H., Patterson, T.F., Rogers, T.R., Schouten, J.A., Spriet, I., Vanderbeke, L., Wauters, J., and van de Veerdonk, F.L.

Subjects
Antifungal Agents/therapeutic use, Aspergillus/isolation & purification, Betacoronavirus, Bronchoalveolar Lavage Fluid/chemistry, Bronchoalveolar Lavage Fluid/microbiology, Coronavirus Infections/complications, Humans, Influenza, Human/complications, Intensive Care Units, Mannans/analysis, Pandemics, Pneumonia, Viral/complications, Pulmonary Aspergillosis/diagnosis, Pulmonary Aspergillosis/etiology, Pulmonary Aspergillosis/prevention & control, COVID-19, ICU, Influenza, Invasive aspergillosis, Viral pneumonia
Abstract

Invasive pulmonary aspergillosis is increasingly reported in patients with influenza admitted to the intensive care unit (ICU). Classification of patients with influenza-associated pulmonary aspergillosis (IAPA) using the current definitions for invasive fungal diseases has proven difficult, and our aim was to develop case definitions for IAPA that can facilitate clinical studies. A group of 29 international experts reviewed current insights into the epidemiology, diagnosis and management of IAPA and proposed a case definition of IAPA through a process of informal consensus. Since IAPA may develop in a wide range of hosts, an entry criterion was proposed and not host factors. The entry criterion was defined as a patient requiring ICU admission for respiratory distress with a positive influenza test temporally related to ICU admission. In addition, proven IAPA required histological evidence of invasive septate hyphae and mycological evidence for Aspergillus. Probable IAPA required the detection of galactomannan or positive Aspergillus culture in bronchoalveolar lavage (BAL) or serum with pulmonary infiltrates or a positive culture in upper respiratory samples with bronchoscopic evidence for tracheobronchitis or cavitating pulmonary infiltrates of recent onset. The IAPA case definitions may be useful to classify patients with COVID-19-associated pulmonary aspergillosis (CAPA), while awaiting further studies that provide more insight into the interaction between Aspergillus and the SARS-CoV-2-infected lung. A consensus case definition of IAPA is proposed, which will facilitate research into the epidemiology, diagnosis and management of this emerging acute and severe Aspergillus disease, and may be of use to study CAPA.

Published
2020

6. Review of influenza-associated pulmonary aspergillosis in ICU patients and proposal for a case definition: an expert opinion

Author

Verweij, P.E. (Paul), Rijnders, B.J.A. (Bart), Brüggemann, M. (Monika), Azoulay, E. (Elie), Bassetti, M. (Matteo), Blot, S. (Stijn), Calandra, T. (Thierry), Clancy, C.J. (Cornelius J.), Cornely, O.A. (Oliver A.), Chiller, T. (Tom), Depuydt, P. (Pieter), Giacobbe, D.R. (Daniele Roberto), Janssen, N.A.F. (Nico A. F.), Kullberg, B.J. (Bart Jan), Lagrou, K. (Katrien), Lass-Flörl, C. (Cornelia), Lewis, R.E. (Russell E.), Liu, P.W.-L. (Peter Wei-Lun), Lortholary, O. (Olivier), Maertens, J. (Johan), Martin-Loeches, I., Nguyen, M.H. (M. Hong), Patterson, T.F. (Thomas F.), Rogers, T.R. (Thomas R.), Schouten, J.A. (Jeroen A.), Spriet, I. (Isabel), Vanderbeke, L. (Lore), Wauters, J. (Joost), Veerdonk, F. (Frank) van de, Verweij, P.E. (Paul), Rijnders, B.J.A. (Bart), Brüggemann, M. (Monika), Azoulay, E. (Elie), Bassetti, M. (Matteo), Blot, S. (Stijn), Calandra, T. (Thierry), Clancy, C.J. (Cornelius J.), Cornely, O.A. (Oliver A.), Chiller, T. (Tom), Depuydt, P. (Pieter), Giacobbe, D.R. (Daniele Roberto), Janssen, N.A.F. (Nico A. F.), Kullberg, B.J. (Bart Jan), Lagrou, K. (Katrien), Lass-Flörl, C. (Cornelia), Lewis, R.E. (Russell E.), Liu, P.W.-L. (Peter Wei-Lun), Lortholary, O. (Olivier), Maertens, J. (Johan), Martin-Loeches, I., Nguyen, M.H. (M. Hong), Patterson, T.F. (Thomas F.), Rogers, T.R. (Thomas R.), Schouten, J.A. (Jeroen A.), Spriet, I. (Isabel), Vanderbeke, L. (Lore), Wauters, J. (Joost), and Veerdonk, F. (Frank) van de

Abstract

Purpose: Invasive pulmonary aspergillosis is increasingly reported in patients with influenza admitted to the intensive care unit (ICU). Classification of patients with influenza-associated pulmonary aspergillosis (IAPA) using the current definitions for invasive fungal diseases has proven difficult, and our aim was to develop case definitions for IAPA that can facilitate clinical studies. Methods: A group of 29 international experts reviewed current insights into the epidemiology, diagnosis and management of IAPA and proposed a case definition of IAPA through a process of informal consensus. Results: Since IAPA may develop in a wide range of hosts, an entry criterion was proposed and not host factors. The entry criterion was defined as a patient requiring ICU admission for respiratory distress with a positive influenza test temporally related to ICU admission. In addition, proven IAPA required histological evidence of invasive septate hyphae and mycological evidence for Aspergillus. Probable IAPA required the detection of galactomannan or positive Aspergillus culture in bronchoalveolar lavage (BAL) or serum with pulmonary infiltrates or a positive culture in upper respiratory samples with bronchoscopic evidence for tracheobronchitis or cavitating pulmonary infiltrates of recent onset. The IAPA case definitions may be useful to classify patients with COVID-19-associated pulmonary aspergillosis (CAPA), while awaiting further studies that provide more insight into the interaction between Aspergillus and the SARS-CoV-2-infected lung. Conclusion: A consensus case definition of IAPA is proposed, which will facilitate research into the epidemiology, diagnosis and management of this emerging acute and severe Aspergillus disease, and may be of use to study CAPA.

Published
2020
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8. Optical studies of strained type II GaAs0.7Sb0.3/GaAs multiple quantum wells

Author

Chen, T.T., Chen, C.H., Cheng, W.Z., Su, W.S., Ya, M.H., Chen, Y.F., Liu, P.W., and Lin, H.H.

Subjects
Antimony -- Research, Antimony -- Optical properties, Antimony -- Electric properties, Quantum wells -- Research, Gallium arsenide -- Research, Gallium arsenide -- Optical properties, Gallium arsenide -- Electric properties, Physics
Abstract

A detailed investigation on the optical transitions of strained type II GaAs0.7Sb0.3/GaAs (100) multiple quantum wells (MQWs) using potoluminescence (PL), potoluminescence excitation (PLE), and photoconductivity (PC) spectroscopies is presented. The experimental results show that the valence band effective masses in GaAsSb can be significantly enhanced due to the strain effect.

Published
2003

10. Strategy of water pollution prevention in Taihu Lake and its effects analysis

Author

Yang, Shuqing, Liu, P.W., Yang, Shuqing, and Liu, P.W.

Abstract

Taihu Lake, the third largest freshwater lake in China, is located in the Chanjiang Delta of the Yangtze River. Its waters are used by agriculture, industry and as major drinking water for several cities including Shanghai and Wuxi. The lake also is important for tourism, aquaculture and flood control. Taihu Lake and its surrounding areas are facing three major water-related threats: deteriorating water quality with inflow and runoff from its watershed; flooding during the rainy seasons; and water shortages during drier months. Noxious algae blooms are occurring with increasing frequency and water quality continues to decline. Remedial actions implemented to date have been ineffective. This paper proposes that the problems could be remedied by constructing a by-pass channel (BPC), which would divert low-quality water from the lake during low precipitation periods and allow better quality water to flow into the lake during high flow periods. This remedial action would simultaneously deal with the deteriorating water quality of Lake Taihu and maintain its water level at a desired level. A preliminary assessment of this strategy shows that, if the BPC were implemented, the water quality of Taihu Lake would be improved significantly in few years, the flood disaster would be greatly mitigated, and the water shortage problem in the basin would be alleviated.

Published
2010

37. Review of influenza-associated pulmonary aspergillosis in ICU patients and proposal for a case definition: an expert opinion

Author

Thomas R. Rogers, Cornelia Lass-Flörl, Stijn Blot, Joost Wauters, Nico A F Janssen, Bart Jan Kullberg, Russell E. Lewis, Pieter Depuydt, Bart J. A. Rijnders, Paul E. Verweij, Cornelius J. Clancy, Johan Maertens, Peter Wei Lun Liu, Roger J. M. Brüggemann, Matteo Bassetti, Jeroen Schouten, Daniele Roberto Giacobbe, Isabel Spriet, Thomas F. Patterson, Olivier Lortholary, Thierry Calandra, Frank L. van de Veerdonk, Katrien Lagrou, M. Hong Nguyen, Tom Chiller, Lore Vanderbeke, Elie Azoulay, Oliver A. Cornely, Ignacio Martin-Loeches, Verweij P.E., Rijnders B.J.A., Bruggemann R.J.M., Azoulay E., Bassetti M., Blot S., Calandra T., Clancy C.J., Cornely O.A., Chiller T., Depuydt P., Giacobbe D.R., Janssen N.A.F., Kullberg B.-J., Lagrou K., Lass-Florl C., Lewis R.E., Liu P.W.-L., Lortholary O., Maertens J., Martin-Loeches I., Nguyen M.H., Patterson T.F., Rogers T.R., Schouten J.A., Spriet I., Vanderbeke L., Wauters J., van de Veerdonk F.L., Internal Medicine, and Medical Microbiology & Infectious Diseases

Subjects
Antifungal Agents, INFECTIOUS-DISEASES SOCIETY, Conference Reports and Expert Panel, lnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4], Disease, Critical Care and Intensive Care Medicine, law.invention, Mannans, Invasive aspergillosi, 0302 clinical medicine, law, Epidemiology, Medicine and Health Sciences, Antifungal Agent, Viral, medicine.diagnostic_test, Respiratory distress, Intensive care unit, Mannan, Intensive Care Units, medicine.anatomical_structure, Aspergillus, PRACTICE GUIDELINES, SAFETY, VORICONAZOLE, VIRUS, Coronavirus Infections, Life Sciences & Biomedicine, CRITICALLY-ILL PATIENTS, Bronchoalveolar Lavage Fluid, medicine.drug, Human, medicine.medical_specialty, Viral pneumonia, Pneumonia, Viral, Intensive Care Unit, DIAGNOSIS, 03 medical and health sciences, Betacoronavirus, Critical Care Medicine, FUNGAL-INFECTIONS, Anesthesiology, General & Internal Medicine, Influenza, Human, medicine, MANAGEMENT, Humans, Intensive care medicine, Pandemics, COVID-19, ICU, Influenza, Invasive aspergillosis, SARS-CoV-2, Pulmonary Aspergillosis, Voriconazole, Lung, Science & Technology, Pandemic, Betacoronaviru, business.industry, Coronavirus Infection, Galactose, 030208 emergency & critical care medicine, Pneumonia, EFFICACY, Aspergillu, Bronchoalveolar lavage, lnfectious Diseases and Global Health Radboud Institute for Health Sciences [Radboudumc 4], 030228 respiratory system, business
Abstract

PURPOSE: Invasive pulmonary aspergillosis is increasingly reported in patients with influenza admitted to the intensive care unit (ICU). Classification of patients with influenza-associated pulmonary aspergillosis (IAPA) using the current definitions for invasive fungal diseases has proven difficult, and our aim was to develop case definitions for IAPA that can facilitate clinical studies. METHODS: A group of 29 international experts reviewed current insights into the epidemiology, diagnosis and management of IAPA and proposed a case definition of IAPA through a process of informal consensus. RESULTS: Since IAPA may develop in a wide range of hosts, an entry criterion was proposed and not host factors. The entry criterion was defined as a patient requiring ICU admission for respiratory distress with a positive influenza test temporally related to ICU admission. In addition, proven IAPA required histological evidence of invasive septate hyphae and mycological evidence for Aspergillus. Probable IAPA required the detection of galactomannan or positive Aspergillus culture in bronchoalveolar lavage (BAL) or serum with pulmonary infiltrates or a positive culture in upper respiratory samples with bronchoscopic evidence for tracheobronchitis or cavitating pulmonary infiltrates of recent onset. The IAPA case definitions may be useful to classify patients with COVID-19-associated pulmonary aspergillosis (CAPA), while awaiting further studies that provide more insight into the interaction between Aspergillus and the SARS-CoV-2-infected lung. CONCLUSION: A consensus case definition of IAPA is proposed, which will facilitate research into the epidemiology, diagnosis and management of this emerging acute and severe Aspergillus disease, and may be of use to study CAPA. ispartof: INTENSIVE CARE MEDICINE vol:46 issue:8 pages:1524-1535 ispartof: location:United States status: published

Published
2020

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