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Your search keyword '"Liu, Naiyu"' showing total 23 results
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23 results on '"Liu, Naiyu"'

1. Fault Line Selection Method in Distribution Network Based on Dilated Convolutional Neural Network

Author

Liu, Yadong, Li, Chenggang, Yang, Xuefeng, Shi, Zhe, Yu, Feitong, Liu, Naiyu, Luo, Guomin, Angrisani, Leopoldo, Series Editor, Arteaga, Marco, Series Editor, Chakraborty, Samarjit, Series Editor, Chen, Shanben, Series Editor, Chen, Tan Kay, Series Editor, Dillmann, Rüdiger, Series Editor, Duan, Haibin, Series Editor, Ferrari, Gianluigi, Series Editor, Ferre, Manuel, Series Editor, Jabbari, Faryar, Series Editor, Jia, Limin, Series Editor, Kacprzyk, Janusz, Series Editor, Khamis, Alaa, Series Editor, Kroeger, Torsten, Series Editor, Li, Yong, Series Editor, Liang, Qilian, Series Editor, Martín, Ferran, Series Editor, Ming, Tan Cher, Series Editor, Minker, Wolfgang, Series Editor, Misra, Pradeep, Series Editor, Mukhopadhyay, Subhas, Series Editor, Ning, Cun-Zheng, Series Editor, Nishida, Toyoaki, Series Editor, Oneto, Luca, Series Editor, Panigrahi, Bijaya Ketan, Series Editor, Pascucci, Federica, Series Editor, Qin, Yong, Series Editor, Seng, Gan Woon, Series Editor, Speidel, Joachim, Series Editor, Veiga, Germano, Series Editor, Wu, Haitao, Series Editor, Zamboni, Walter, Series Editor, Tan, Kay Chen, Series Editor, Yang, Qingxin, editor, and Li, Jian, editor

Published
2025
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13. Longitudinal failure criterion considering local fiber misplacement for UD composites.

Author

Chen, Xiangming, Yu, Fei, Tang, Xinhao, Wang, Binwen, Liu, Naiyu, Yang, Junchao, and Chen, Puhui

Subjects
FIBROUS composites, FIBERS, POLYNOMIALS
Abstract

A new longitudinal failure criterion for unidirectional fibre reinforced (UD) composites is proposed, incorporating the contribution of local fibre misalignment to fibre failure. The failure function was established based on the quadratic polynomial expansion of stress components in the local coordinate system parallel to the misaligned fibres, with coefficients rationally determined based on the basic strength parameters of UD composites. The local stress components were used to determine the failure status associated with fibre compression, while the tensile load along fibres was assumed to have negligible influence on the development of the fibre misalignment. The predicted failure envelopes agreed well with the experimental data for different stress combinations, particularly in the regimes where the fibre failure was influenced by transverse stresses. This validates the predictive ability of the proposed criteria and highlights the importance of the contribution of matrix-failure-related stresses to the fibre-dominated failure behaviour of fibre reinforced composites. [ABSTRACT FROM AUTHOR]

Published
2024
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15. An Overview of Excipients Classification and Their Use in Pharmaceuticals

Author

Chen Gang, Liang Jian, Shen Xiong, Kardooni Rezvan, Elsayed Khaled, Chen Guilliang, Liu Naiyu, L. Viana Mirelle, D. Tsiailanis Antonis, Zheng Luxia, G. Tzakos Andreas, A. Verediano Thaísa, Mavromoustakos Thomas, Xu Mingming, Pei Xiaming, Fathy Wael, Esim Ozgur, Wen Chaoqi, Ou Hailong, S. Sutar Radhakrishna, Ma Yihan, Wang Yingchun, Tullius Scotti Marcus, Tawfik Eman, K. Patil Meghshyam, Peng Chen, S. Abdelhameed Mohamed, Hammouda Ola, Ozkan Yalcin, das G.V. Tostes Maria, Kose Ozkan Cansel, M.B. Costa Neuza, Hu Xiaoxiao, Liu Yunyi, Savaser Ayhan, Jiang Bin, Fang Xinxin, P. Barkul Rani, Reza Kiasat Ali, Zaki Ayman, and Essawy Ehab

Subjects
Chemistry, Biophysics, Pharmaceutical Science, Molecular Medicine, Biochemical engineering, Biochemistry
Abstract

The content and the application of pharmaceutical dosage forms must meet several basic requirements to ensure and maintain efficiency, safety and quality. A large number of active substances have a limited ability to direct administration. Excipients are generally used to overcome the limitation of direct administration of these active substances. However, the function, behavior and composition of the excipients need to be well known in the design, development and production of pharmaceutical dosage forms. In this review, excipients used to assist in any pharmaceutical dosage form production processes of drugs, to preserve, promote or increase stability, bioavailability and patient compliance, to assist in product identification/separation, or to enhance overall safety and effectiveness of the drug delivery system during storage or use are explained. Moreover, the use of these excipients in drug delivery systems is identified. Excipient toxicity, which is an issue discussed in the light of current studies, also discussed in this review.

Published
2021
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22. Chemo-drug Controlled-release Strategies of Nanocarrier in the Development of Cancer Therapeutics

Author

Ma Yihan, Cheng Peng, Chaoqi Wen, Liu Naiyu, Hailong Ou, Yunyi Liu, Xiaming Pei, Hu Xiaoxiao, and Bin Jiang

Subjects
Drug, Side effect, Drug-Related Side Effects and Adverse Reactions, media_common.quotation_subject, Cancer therapy, Future application, Nanotechnology, Biochemistry, Drug Delivery Systems, Neoplasms, Drug Discovery, medicine, Humans, media_common, Pharmacology, Drug Carriers, Chemistry, Organic Chemistry, Cancer, medicine.disease, Controlled release, Drug Liberation, Delayed-Action Preparations, Drug delivery, Molecular Medicine, Nanoparticles, Nanocarriers
Abstract

Nanoparticles have been widely used in cancer therapy because of its nanoscale, high surface ratio, multifuntions and so on. With specific construction of nanoparticles, such as choosing magnetic nanomaterials or citric acid coated nanoparticle, scientists can kill tumor cells effectively and accurately，importantly， reducing the side effect of conventional chemotherapy. Currently, they have been continually applied in cancer therapeutics research. Scientists not only designed nanoparticles loading with therapeutic drugs, but also equipped with targeted molecules. These works make nanoparticles become a multifuntional nanocarrier. In the construction of multifunctional nanocarriers, nanoparticles play the important work of drug delivery. Normally, enabling drugs delivery to tumor tissues is a difficult task. During the period of internal circulation, it is hard to keep the nanocarriers stability. As well as not attach to normal cells or serum. With the application of stimulus-responsive nanomaterials, scientists develop many nanocarriers with controllable drug release. These controllable drug delivery systems can quickly respond to microenvironmental changes (PH, enzyme, etc.) or external stimuli (photo, heat, magnetic or electric fields). Thus, it is to overcome the side effects by controllable drug delivery systems in vivo. In this article, we summarize the various kinds of stimulus-responsive nanocarriers for cancer therapy and discuss its possibilities and challenges in future application.

Published
2019

23. A Novel Manganese Ion Delivery Carrier Promotes Immune Cell Proliferation and Enhances Innate Immune Responses.

Author

Wang L, Tang T, Zuo K, Liu N, Wei Y, and Zhu X

Abstract

Manganese is a transition metal that is an essential trace element for human health. Manganese ions (Mn 2+ ), which serve as one of the most common transition metal ions, play vital roles in enhancing innate immune responses. However, immune agonists based on Mn 2+ are poorly utilized in clinical trials due to poor chemodynamics and adverse events. In this work, we designed a novel delivery carrier for loading manganese ions by constructing hFn-MT3(Mn 2+ ) protein nanoparticles (termed as NPs(Mn 2+ )), which contained human ferritin heavy chain (hFn) and metallothionein-3 (MT3), induced by isopropyl β-d-thiogalactoside (IPTG) and manganese ions in the prokaryotic expression system. The NPs(Mn 2+ ) protein nanoparticles could not only stimulate immune cell proliferation but also activate innate immune responses via the cGAS-STING-IRF3 signaling pathway. Collectively, our results unveil a candidate strategy for delivering metal ions beyond Mn 2+ and may broaden metal ion clinical use in the field of immunotherapies., Competing Interests: The authors declare no competing financial interest., (© 2024 The Authors. Published by American Chemical Society.)

Published
2024
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