Search

Your search keyword '"Liu, Guangxu"' showing total 533 results
Start Over Author "Liu, Guangxu"
533 results on '"Liu, Guangxu"'

3. List of contributors

Author

Bao, Yongbo, primary, Chen, Liming, additional, Deng, Fujing, additional, Han, Yu, additional, Hou, Jing, additional, Huang, Lin, additional, Liu, Guangxu, additional, Liu, Hongxing, additional, Liu, Jindian, additional, Liu, Zhiquan, additional, Lv, Lu, additional, Shi, Wei, additional, Wang, Dou, additional, Wang, Yanhua, additional, Wang, Youji, additional, Yuan, Xia, additional, Zha, Shanjie, additional, Zhang, Hangjun, additional, Zhang, Miaolian, additional, Zhang, Weixia, additional, Zhong, Zhen, additional, and Zhou, Weishang, additional

Published
2024
Full Text
View/download PDF

12. High temperature oxidation microstructure analysis of Ni-based P/M superalloy coated with an inorganic aluminum coating

Author

LI Jialin, YANG Jie, MU Chunhui, JIANG Guojie, LIU Guangxu, WANG Xiaofeng, and ZOU Jinwen

Subjects
twl12+twl20 inorganic aluminum coating, ni-based p/m superalloy, high temperature oxidation, microstructure, Motor vehicles. Aeronautics. Astronautics, TL1-4050
Abstract

In this paper, TWL12 + TWL20 inorganic salt aluminum coating was sprayed on the surface of Ni-based P/M superalloy. The microstructure changes of inorganic salt aluminum coating and P/M superalloy after high temperature oxidation at 700, 750 ℃ and 800 ℃ were studied by XRD, SEM, EPMA and TEM. The results show that after high temperature oxidation, the surface structure of the coating peels off, and the aluminum in the coating diffuses with the substrate to form a transition layer composed of oxidation zone, diffusion layer and interdiffusion zone. The oxidation zone is the outermost layer, where is mainly enriched with O and Al elements to form Al2O3 layer. The diffusion layer mainly contains Ni and Al elements, forming NiAl phase and α-Cr phase dispersed in it. Finally, the interdiffusion zone rich in Ti, Cr, Co, Ta and other elements exists between the diffusion zone and the matrix, which is mainly composed of Ni2AlTi phase matrix and σ phase dispersed in it. The analysis shows that the thickness of transition layer changes with the increase of oxidation temperature, it is mainly manifested by the increase of the width of the interdiffusion zone, the increase of the size of α-Cr phase in the diffusion layer and σ phase in the interdiffusion zone, and the growth trend of σ phase along the vertical transition zone is intensified. The oxidation weight gain curve shows that the transition layer exhibits good oxidation resistance during high temperature oxidation at 750 ℃ and 800 ℃ after the surface structure of the coating falls off, it indicates that the TWL12 + TWL20 inorganic salt aluminum coating has the potential to provide high temperature oxidation coating protection for advanced P/M superalloy used in aeroengines.

Published
2023
Full Text
View/download PDF

44. Assessment of Nonalcoholic Fatty Liver Disease Symptoms and Gut-Liver Axis Status in Zebrafish after Exposure to Polystyrene Microplastics and Oxytetracycline, Alone and in Combination

Author

Zhou, Weishang, Shi, Wei, Du, Xueying, Han, Yu, Tang, Yu, Ri, Sanghyok, Ju, Kwangjin, Kim, Tongchol, Huang, Lin, Zhang, Weixia, Yu, Yihan, Tian, Dandan, Yu, Yingying, Chen, Liangbiao, Wu, Zhichao, and Liu, Guangxu

Subjects
Microbiota (Symbiotic organisms) -- Health aspects, Pollution -- Health aspects, Oxytetracycline -- Complications and side effects, Fatty liver -- Risk factors -- Environmental aspects -- Models, Zebra fish -- Physiological aspects, Polystyrene -- Health aspects, Environmental issues, Health
Abstract

Background: Environmental pollution may give rise to the incidence and progression of nonalcoholic fatty liver disease (NAFLD), the most common cause for chronic severe liver lesions. Although knowledge of NAFLD pathogenesis is particularly important for the development of effective prevention, the relationship between NAFLD occurrence and exposure to emerging pollutants, such as microplastics (MPs) and antibiotic residues, awaits assessment. Objectives: This study aimed to evaluate the toxicity of MPs and antibiotic residues related to NAFLD occurrence using the zebrafish model species. Methods: Taking common polystyrene MPs and oxytetracycline (OTC) as representatives, typical NAFLD symptoms, including lipid accumulation, liver inflammation, and hepatic oxidative stress, were screened after 28-d exposure to environmentally realistic concentrations of MPs (0.69 mg/L) and antibiotic residue (3.00 lg/L). The impacts of MPs and OTC on gut health, the gut-liver axis, and hepatic lipid metabolism were also investigated to reveal potential affecting mechanisms underpinning the NAFLD symptoms observed. Results: Compared with the control fish, zebrafish exposed to MPs and OTC exhibited significantly higher levels of lipid accumulation, triglycerides, and cholesterol contents, as well as inflammation, in conjunction with oxidative stress in their livers. In addition, a markedly smaller proportion of Proteobacteria and higher ratios of Firmicutes/Bacteroidetes were detected by microbiome analysis of gut contents in treated samples. After the exposures, the zebrafish also experienced intestinal oxidative injury and yielded significantly fewer numbers of goblet cells. Markedly higher levels of the intestinal bacteria-sourced endotoxin lipopolysaccharide (LPS) were also detected in serum. Animals treated with MPs and OTC exhibited higher expression levels of LPS binding receptor (LBP) and downstream inflammation-related genes while also exhibiting lower activity and gene expression of lipase. Furthermore, MP-OTC coexposure generally exerted more severe effects compared with single MP or OTC exposure. Discussion: Our results suggested that exposure to MPs and OTC may disrupt the gut-liver axis and be associated with NAFLD occurrence. https://doi.org/10.1289/EHP11600, Introduction Nonalcoholic fatty liver disease (NAFLD), characterized by excessive fat accumulation in hepatocytes, was suggested to be the most common cause of chronic liver lesions. (1) Recent surveys have demonstrated [...]

Published
2023
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results