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Realizing the synergy of regional economic growth and ecological development can not only effectively promote the construe -tion of ecological civilization, but also help accelerate the green transformation of the development mode. For this, from the perspective of strong sustainability and the common frontier theory, using the panel data of 285 prefecture-level cities in China from 2011 to 2020 and considering the characteristics of regional technological heterogeneity, this study used the three-stage SBM model based on the common frontier to measure urban ecological total factor productivity. The study also used the spatial Durbin panel model to analyze the spatial spillover effects and influencing factors of urban ecological total factor productivity. The findings showed that: (J) After excluding the influence of external environmental factors and random factors, the ecological total factor productivity of each region decreased significantly compared with that before the improvement. From the perspective of average efficiency by region, there was a characteristic of east>northeast>west>center. © Under different spatial weight matrices, urban ecological total factor productivity had obvious spatial spillover effects, and there were differences in characteristics. © From the perspective of geographical location, economic development level, and resource endowment differences, the spatial spillover effects of ecological total factor productivity in China's eastern regions and non-resource depletion cities were more obvious, while those in the central and western regions, northeastern regions, and resource depletion cities were average. © The improvement of urban ecological total factor productivity could not be separated from the cooperation and exchange between neighboring regions, thus forming a development pattern of partnership with mutual benefits. Therefore, in the new era of China's economic transformation and development, it is necessary to pay attention to improving the efficiency of factor and resource utilization and fully consider the technological gaps between different regions. At the same time, it is also necessary to deepen and coordinate the pattern of regionally coordinated development, improve the innovation systems and mechanisms in policy formulation, and promote the sustainable growth of regional ecological total factor productivity so as to form a mutually beneficial and win-win development pattern among regions. [ABSTRACT FROM AUTHOR]