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1. Contributors

Author

Abello, Eric H., primary, Abiri, Arash, additional, Adappa, Nithin D., additional, Ahmad, Meleha, additional, Almeida, Joao Paulo, additional, Alrasheed, Abdulaziz S., additional, Arrighi-Allisan, Annie, additional, Barton, Blair M., additional, Bastien, Amanda J., additional, Battaglia, Paolo, additional, Biousse, Valérie, additional, Bleier, Benjamin S., additional, Carrau, Ricardo L., additional, Castelnuovo, Paolo, additional, Chaaban, Mohamad R., additional, Chan, David, additional, Chemas-Velez, Maria Manuela, additional, Chen, Benson S., additional, Chou, Brian W., additional, Cote, David J., additional, Cutsforth-Gregory, Jeremy K., additional, Czaczkes, Camilla, additional, Dalfino, Gianluca, additional, Das, Paramita, additional, Junior de Andrade, Erion, additional, Filho, Leonardo de Macedo, additional, Eloy, Jean Anderson, additional, Evans, James J., additional, Fang, Christina H., additional, Filip, Peter, additional, Francis, Courtney E., additional, Gallia, Gary L., additional, Gardner, Paul A., additional, Gentili, Fred, additional, Georgalas, Christos, additional, Ginat, Daniel T., additional, Gogia, Angad S., additional, Govindaraj, Satish, additional, Grayson, Jessica W., additional, Gudis, David A., additional, Halderman, Ashleigh A., additional, Harvey, Richard J., additional, Hernandez, Stephen, additional, Higgins, Mamie, additional, Horowitz, Peleg Moshe, additional, Illing, Elisa A., additional, Ishii, Masaru, additional, Kamel, Peter, additional, Kang, Keiko M., additional, Karp, Emily, additional, Karsy, Michael J., additional, Kshettry, Varun R., additional, Kshirsagar, Rijul S., additional, Kuan, Edward C., additional, Lamarre, Eric, additional, Levy, Joshua M., additional, Link, Michael, additional, Little, Andrew S., additional, Liu, Ann, additional, Liu, James K., additional, Locatelli, Davide, additional, Luna, Licia P., additional, Mahomva, Chengetai, additional, McCulley, Timothy J., additional, Medina, Eduardo J., additional, Michael, Alex P., additional, Miglani, Amar, additional, Mihal, David, additional, Moe, Kris S., additional, Nadgir, Rohini, additional, Nicholson, Patrick, additional, Nyquist, Gurston G., additional, Oostra, Amanda, additional, Oswald, Aaron, additional, Palmer, James N., additional, Parsel, Sean M., additional, Patel, Prayag, additional, Petrauskas, Laura, additional, Porto, Edoardo, additional, Pradilla, Gustavo, additional, Prashant, Giyarpuram N., additional, Prevedello, Daniel, additional, Qureshi, Hannan A., additional, Rabinowitz, Mindy R., additional, Radovanovic, Ivan, additional, Ramanathan, Murugappan, additional, Rao, Shilpa M., additional, Ray, Amrita, additional, Rech, Matheus, additional, Recinos, Pablo F., additional, Barbero, J. Manuel Revuelta, additional, Rincon-Torroella, Jordina, additional, Rosen, Marc R., additional, Roxbury, Christopher R., additional, Ruggieri, Paul, additional, Safi, Chetan, additional, Santarelli, Griffin D., additional, Sarris, Christina E., additional, Schlosser, Rodney J., additional, Schwartz, Theodore H., additional, Shah, Janki, additional, Sindwani, Raj, additional, Snyderman, Carl H., additional, Sommerfeld, Connor, additional, Soriano, Roberto M., additional, Sreenath, Satyan B., additional, Stokken, Janalee, additional, Tabaee, Abtin, additional, Tang, Dennis M., additional, Timmons, Shelly D., additional, Ting, Jonathan, additional, Turri-Zanoni, Mario, additional, Vorster, Sarel J., additional, Vyskocil, Erich, additional, Warren, Zachary, additional, Watley, Duncan C., additional, White, Alexandra J., additional, Williams, Michael A., additional, Woodard, Troy D., additional, Woodworth, Bradford A., additional, Workman, Alan D., additional, Wormald, Peter-John, additional, Wrobel, Bozena B., additional, Zada, Gabriel, additional, Zanation, Adam, additional, Zhao, Jiawei, additional, and Zimmer, David I., additional

Published
2024
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8. Multicenter Registry of Adenomas of the Pituitary and Related Disorders: Initial Description of Cushing Disease Cohort, Surgical Outcomes, and Surgeon Characteristics.

Author

Little, Andrew S., Karsy, Michael, Evans, James J., Won Kim, Pacione, Donato R., Kim, Albert H., Gardner, Paul A., Hendricks, Benjamin K., Sarris, Christina E., Torok, Ildiko E., Low, Trevor M., Crocker, Tomiko A., Valappil, Benita, Kanga, Mridu, Abdallah, Hussein, Collopy, Sarah, Fernandez-Miranda, Juan C., Vigo, Vera, Ljubimov, Vladimir A., and Zada, Gabriel

Published
2024
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9. Unplanned Hospital Readmissions Following Trans-sphenoidal Surgery for Cushing's Disease from a Multicenter Pituitary Surgery Outcomes Registry of 26 Surgeons

Author

Pacult, Mark A, additional, Karsy, Michael, additional, Evans, James J., additional, Kim, Won, additional, Pacione, Donald R., additional, Kim, Albert H., additional, Gardner, Paul A., additional, Hendricks, Benjamin K., additional, Sarris, Christina E., additional, Torok, Ildiko E., additional, Low, Trevor M., additional, Crocker, Tomiko A., additional, Valappil, Benita, additional, Kanga, Mridu, additional, Abdallah, Hussein, additional, Collopy, Sarah, additional, Fernandez-Miranda, Juan C, additional, Vigo, Vera, additional, Delery, William, additional, Yuen, Kevin C., additional, Rennert, Robert C., additional, Couldwell, Wiilliam T., additional, Silverstein, Julie M., additional, Kshettry, Varun R., additional, Chicoine, Michael R., additional, and Little, Andrew S., additional

Published
2024
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16. Founding of a National Surgical Research Consortium for Pituitary Disorders: Description of Cushing's Disease Cohort, Surgeon Characteristics, and Report of Outcomes.

Author

Little, Andrew S., Karsy, Michael, Evans, James, Kim, Won, Gardner, Paul, Pacione, Donato, Kim, Albert, Torok, Ildiko, Crocker, Tomi, Low, Trevor, Silverstein, Julie, Rennert, Robert, Wu, Kyle, Couldwell, William, Abdallah, Hussein, Garrett, Trey, Vigo, Vera, Fernandez-Miranda, Juan, Zada, Gabriel, and Barkhoudarian, Garni

Subjects
*CUSHING'S syndrome, *CONSORTIA, *SURGEONS
Abstract

This article discusses the establishment of a national pituitary surgical research platform called RAPID, which aims to improve patient care and surgical outcomes for pituitary disorders. The initial focus of the collaboration is on Cushing's disease. The study provides an overview of the patient cohort, surgical outcomes, and lays the foundation for future research. The data collected from nine academic pituitary centers shows that 528 patients with Cushing's disease were treated by 26 neurosurgeons from 2003 to 2023. The report highlights insights into surgical outcomes and disease recurrence rates across different surgeons and environments. The collaboration is expected to advance the standard of care for patients with pituitary disorders. [Extracted from the article]

Published
2024
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18. A Prospective, Multicenter, Observational Study of Surgical vs Nonsurgical Management for Pituitary Apoplexy.

Author

Mamelak, Adam N, Little, Andrew S, Gardner, Paul A, Almeida, João Paulo, Recinos, Pablo, Soni, Pranay, Kshettry, Varun R, Jane, John A, Barkhoudarian, Garni, Kelly, Daniel F, Dodd, Robert, Mukherjee, Debraj, Gersey, Zachary C, Fukuhara, Noriaki, Nishioka, Hiroshi, Kim, Eui-Hyun, Litré, Claude-Fabien, Sina, Elliott, Mazer, Mia W, and Cui, Yujie

Subjects
PITUITARY tumors, NEUROSURGERY, PATIENT reported outcome measures
Abstract

Context Pituitary apoplexy (PA) has been traditionally considered a neurosurgical emergency, yet retrospective single-institution studies suggest similar outcomes among patients managed medically. Objective We established a multicenter, international prospective registry to compare presentation and outcomes in PA patients treated with surgery or medical management alone. Methods A centralized database captured demographics, comorbidities, clinical presentation, visual findings, hormonal status, and imaging features at admission. Treatment was determined independently by each site. Key outcomes included visual, oculomotor, and hormonal recovery, complications, and hospital length of stay. Outcomes were also compared based on time from symptom onset to surgery, and from admission or transfer to the treating center. Statistical testing compared treatment groups based on 2-sided hypotheses and P less than.05. Results A total of 100 consecutive PA patients from 12 hospitals were enrolled, and 97 (67 surgical and 30 medical) were evaluable. Demographics, clinical features, presenting symptoms, hormonal deficits, and imaging findings were similar between groups. Severe temporal visual field deficit was more common in surgical patients. At 3 and 6 months, hormonal, visual, and oculomotor outcomes were similar. Stratifying based on severity of visual fields demonstrated no difference in any outcome at 3 months. Timing of surgery did not affect outcomes. Conclusion We found that medical and surgical management of PA yield similar 3-month outcomes. Although patients undergoing surgery had more severe visual field deficits, we could not clearly demonstrate that surgery led to better outcomes. Even without surgery, apoplectic tumor volumes regress substantially within 2 to 3 months, indicating that surgery is not always needed to reduce mass effect. [ABSTRACT FROM AUTHOR]

Published
2024
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19. A prospective multi-center observational study of surgical versus non-surgical management for pituitary apoplexy

Author

Mamelak, Adam N, primary, Little, Andrew S, additional, Gardner, Paul A, additional, Almeida, João Paulo, additional, Recinos, Pablo, additional, Soni, Pranay, additional, Kshettry, Varun R, additional, Jane, John A, additional, Barkhoudarian, Garni, additional, Kelly, Daniel F, additional, Dodd, Robert, additional, Mukherjee, Debraj, additional, Gersey, Zachary C, additional, Fukuhara, Noriaki, additional, Nishioka, Hiroshi, additional, Kim, Eui-Hyun, additional, Litré, Claude-Fabien, additional, Sina, Elliott, additional, Mazer, Mia W, additional, Cui, Yujie, additional, and Bonert, Vivien, additional

Published
2023
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20. Intraoperative in vivo confocal laser endomicroscopy imaging at glioma margins: can we detect tumor infiltration?

Author

Xu, Yuan, primary, Mathis, Andrea M., additional, Pollo, Bianca, additional, Schlegel, Jürgen, additional, Maragkou, Theoni, additional, Seidel, Kathleen, additional, Schucht, Philippe, additional, Smith, Kris A., additional, Porter, Randall W., additional, Raabe, Andreas, additional, Little, Andrew S., additional, Sanai, Nader, additional, Agbanyim, Dennis C., additional, Martirosyan, Nikolay L., additional, Eschbacher, Jennifer M., additional, Quint, Karl, additional, Preul, Mark C., additional, and Hewer, Ekkehard, additional

Published
2023
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28. Intraoperative confocal laser endomicroscopy: prospective in vivo feasibility study of a clinical-grade system for brain tumors

Author

Abramov, Irakliy, primary, Park, Marian T., additional, Belykh, Evgenii, additional, Dru, Alexander B., additional, Xu, Yuan, additional, Gooldy, Timothy C., additional, Scherschinski, Lea, additional, Farber, S. Harrison, additional, Little, Andrew S., additional, Porter, Randall W., additional, Smith, Kris A., additional, Lawton, Michael T., additional, Eschbacher, Jennifer M., additional, and Preul, Mark C., additional

Published
2023
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30. Drivers of Hospital Financial Performance and Patient Outcomes in Cushing Disease

Author

Furey, Charuta G., additional, Bauer, Izzi, additional, Cossio, Frank, additional, Farhadi, Dara S., additional, Smith, Elizabeth, additional, Torok, Ildiko, additional, Low, Trevor, additional, Crocker, Tomi, additional, Asher, Anthony M., additional, Sarris, Christina E., additional, Hendricks, Benjamin K., additional, Brigeman, Scott T., additional, and Little, Andrew S., additional

Published
2023
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32. Development of Human Pituitary Neuroendocrine Tumor Organoids to Facilitate Effective Targeted Treatments of Cushing’s Disease

Author

Chakrabarti, Jayati, primary, Pandey, Ritu, additional, Churko, Jared M., additional, Eschbacher, Jennifer, additional, Mallick, Saptarshi, additional, Chen, Yuliang, additional, Hermes, Beth, additional, Mallick, Palash, additional, Stansfield, Ben N., additional, Pond, Kelvin W., additional, Thorne, Curtis A., additional, Yuen, Kevin C. J., additional, Little, Andrew S., additional, and Zavros, Yana, additional

Published
2022
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35. Genetically Engineered Human Pituitary Corticotroph Tumor Organoids Exhibit Divergent Responses To Glucocorticoid Receptor Modulators

Author

Mallick, Saptarshi, primary, Chakrabarti, Jayati, additional, Eschbacher, Jennifer, additional, Moraitis, Andreas G., additional, Greenstein, Andrew E., additional, Churko, Jared, additional, Pond, Kelvin W., additional, Livolsi, Antonia, additional, Thorne, Curtis, additional, Little, Andrew S., additional, Yuen, Kevin C.J., additional, and Zavros, Yana, additional

Published
2022
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38. Effects of a transsphenoidal surgery quality improvement program on patient outcomes and hospital financial performance

Author

Sarris, Christina E., primary, Brigeman, Scott T., additional, Doris, Estelle, additional, Bobrowitz, Maggie, additional, Rowe, Thomas, additional, Duran, Eva M., additional, Santarelli, Griffin D., additional, Rehl, Ryan M., additional, Ovanessoff, Garineh, additional, Rodriguez, Monica C., additional, Buddhdev, Kajalben, additional, Yuen, Kevin C. J., additional, and Little, Andrew S., additional

Published
2022
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