Search

Your search keyword '"Lisoway, Amanda J."' showing total 13 results
Start Over Author "Lisoway, Amanda J."
13 results on '"Lisoway, Amanda J."'

7. W5. INVESTIGATING THE GENETIC LINK BETWEEN HEART RATE VARIABILITY (HRV) AND ANXIETY DISORDERS: POLYGENIC RISK SCORE OVERLAP AND ASSOCIATION OF HRV GENOME-WIDE POLYMORPHISMS WITH ANXIETY

Author

Tomasi, Julia, primary, Lisoway, Amanda J., additional, Zai, Clement C., additional, Zai, Gwyneth, additional, Richter, Margaret A., additional, Herbert, Deanna, additional, Mohiuddin, Ayeshah G., additional, Sanches, Marcos, additional, Tiwari, Arun K., additional, and Kennedy, James L., additional

Published
2023
Full Text
View/download PDF

9. User Experiences of Pharmacogenomic Testing and Opinions among Psychiatry Patients.

Author

Virelli, Catherine R., Ebrahimi, Mahbod, Mohiuddin, Ayeshah G., Tomasi, Julia, Lisoway, Amanda J., Herbert, Deanna, Marshe, Victoria S., Kidd, Sean A., Ferenbok, Joseph, and Kennedy, James L.

Subjects
PATIENTS' attitudes, USER experience, GENETIC profile, FOCUS groups, PSYCHIATRY
Abstract

Pharmacogenomic testing (PGx) is a tool used to guide physicians in selecting an optimal medication for clients based on their genetic profile. The objective of this qualitative study is to understand patients' experiences with PGx testing as well as their opinions regarding the clinical adoption of such tests in psychiatry. A focus group was conducted to assess the needs of clients who had experience using a PGx test. Participants were recruited from a large study on PGx testing that offered physicians an opportunity to use PGx reports to guide psychotropic prescriptions. The focus group discussions were recorded, transcribed, and coded using NVivo to identify core themes. A total of 11 people participated in the focus group. Our analysis revealed that many participants were in favour of implementing PGx testing in psychiatric practice, and all expressed important considerations for patient-centred optimization of PGx testing. The main themes captured were: education and awareness among clinicians, cost considerations, PGx results-sharing and accessibility, and prospective benefits. The results of this study suggest that patients are keen to see PGx testing in widespread clinical care, but they report important opportunities to improve knowledge mobilization of PGx testing. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

13. Integrating genetic variation with DNA methylation at SKA2rs7208505 in analyses of obsessive-compulsive disorder disease risk and symptom severity

Author

Lisoway, Amanda J., Zai, Clement C., Tiwari, Arun K., Nair, Akhil, Ebrahimi, Sasha, Gonçalves, Vanessa F., Zai, Gwyneth, Kaminsky, Zachary A., Richter, Margaret A., and Kennedy, James L.

Abstract

Obsessive-Compulsive Disorder (OCD) has a complex genetic component and may be preceded by environmental stressors. The spindle and kinetochore associated complex subunit 2 (SKA2)gene interacts with the glucocorticoid receptor and is implicated in mediating hypothalamic–pituitary-adrenal (HPA) axis function but has yet to be examined in OCD. We hypothesized that genetic and epigenetic variation of SKA2may be involved in OCD disease risk and symptom severity.

Published
2020
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results