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2. Histologische Diagnostik

Author

Möckel, Sigrid M. C., Lippert, Undine, Schön, Michael P., Skudlik, Christoph, editor, Schön, Michael Peter, editor, and John, Swen Malte, editor

Published
2023
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3. Response of eosinophilic fasciitis associated with Waldenström macroglobulinemia to rituximab

Author

Kromer, Christian, Matzke, Silke S, Bleckmann, Annalen, Overbeck, Tobias, Lippert, Undine, Schön, Michael P, and Mössner, Rotraut

Subjects
biologic, localized scleroderma, rituximab, Shulman's syndrome
Abstract

Eosinophilic fasciitis (EF) and generalized morphea (GM) are rare and difficult-to-treat sclerosing skin diseases which may occur in association with hematologic disorders. We present a 66-year-old man with EF and associated Waldenström macroglobulinemia who received combination therapy with rituximab (375mg/m2 every other week, gradually extended to every eight weeks), prednisolone (1.25-30mg/d), and methotrexate (7.5-15mg/w). Three months after rituximab initiation, his skin condition improved steadily accompanied by a significant improvement in joint mobility with only mild and transitory flares (observation period: 59 months under treatment with rituximab). To date, there are five case reports on rituximab treatment of EF/GM with an association to hypergammaglobulinemia in three of those cases. Therapy effected significant improvement in four patients. Our case adds to the hitherto limited evidence that rituximab may be a promising therapeutic strategy for EF/GM in association with hypergammaglobulinemia.

Published
2021

6. Differential diagnosis between urticarial vasculitis and chronic spontaneous urticaria: An international Delphi survey

Author

Krause, Karoline, primary, Bonnekoh, Hanna, additional, Jelden‐Thurm, Jannis, additional, Asero, Riccardo, additional, Gimenez‐Arnau, Ana Maria, additional, Cardoso, José C., additional, Grattan, Clive, additional, Kocatürk, Emek, additional, Lippert, Undine, additional, Maurer, Marcus, additional, Metz, Martin, additional, Staubach, Petra, additional, Goncalo, Margarida, additional, and Kolkhir, Pavel, additional

Published
2023
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9. The global impact of the COVID-19 pandemic on the management and course of chronic urticaria

Author

Kocatürk, Emek, Salman, Andaç, Cherrez-Ojeda, Ivan, Criado, Paulo Ricardo, Peter, Jonny, Comert-Ozer, Elif, Abuzakouk, Mohamed, Câmara Agondi, Rosana, Al-Ahmad, Mona, Altrichter, Sabine, Arnaout, Rand, Arruda, Luisa Karla, Asero, Riccardo, Bauer, Andrea, Ben-Shoshan, Moshe, Bernstein, Jonathan, Bizjak, Mojca, Boccon-Gibod, Isabelle, Bonnekoh, Hanna, Bouillet, Laurence, Brzoza, Zenon, Busse, Paula, Campos, Regis A., Carne, Emily, Conlon, Niall, Criado, Roberta Fachini Jardim, De Souza Lima, Eduardo Magalhães, Demir, Semra, Dissemond, Joachim, Doğan Günaydın, Sibel, Dorofeeva, Irina, Ensina, Luis Felipe, Ertaş, Ragip, Ferrucci, Silvia Mariel, Figueras-Nart, Ignasi, Fomina, Daria, Franken, Sylvie M., Fukunaga, Atsushi, Giménez Arnau, Ana M, Godse, Kiran, Gonçalo, Margarida, Gotua, Maia, Grattan, Clive, Guillet, Carole, Inomata, Naoko, Jakob, Thilo, Karakaya, Gul, Kasperska-Zając, Alicja, Katelaris, Constance H., Košnik, Mitja, Krasowska, Dorota, Kulthanan, Kanokvalai, Kumaran, M.Sendhil, Lang, Claudia, Larco-Sousa, José Ignacio, Lazaridou, Elisavet, Leslie, Tabi Anika, Lippert, Undine, Calderón llosa, Oscar, Makris, Michael, Marsland, Alexander, Medina, Iris V., Meshkova, Raisa, Bastos Palitot, Esther, Parisi, Claudio A.S., Pickert, Julia, Ramon, Germán D., Rodríguez-Gonzalez, Mónica, Rosario, Nelson, Rudenko, Michael, Rutkowski, Krzysztof, Sánchez Caraballo, Jorge Mario, Schliemann, Sibylle, Sekerel, Bulent Enis, Serpa, Faradiba S., Serra-Baldrich, E, Song, Zhiqiang, Soria, Angèle, Staevska, Maria, Staubach, Petra, Tagka, Anna, Takahagi, Shunsuke, Thomsen, Simon Francis, Treudler, Regina, Vadasz, Zahava, Rodrigues Valle, Solange Oliveira, Van Doorn, Martijn B.A., Vestergaard, Christian, Wagner, Nicola, Wang, Dahu, Wang, Liangchun, Wedi, Bettina, Xepapadaki, Paraskevi, Yücel, Esra, Zalewska-Janowska, Anna, Zhao, Zuotao, Zuberbier, Torsten, Maurer, Marcus, Universitat Autònoma de Barcelona, Dermatology, Göncü, Özgür Emek Kocatürk (ORCID 0000-0003-2801-0959 & YÖK ID 217219), Salman, A., Cherrez-Ojeda, I., Criado, P. R., Peter, J., Comert-Ozer, E., Abuzakouk, M., Agondi, R. C., Al-Ahmad, M., Altrichter, S., Arnaout, R., Arruda, L. K., Asero, R., Bauer, A., Ben-Shoshan, M., Bernstein, J. A., Bizjak, M., Boccon-Gibod, I., Bonnekoh, H., Bouillet, L., Brzoza, Z., Busse, P., Campos, R. A., Carne, E., Conlon, N., Criado, R. F., Lima, E. M. D., Demir, S., Dissemond, J., Gunaydin, S. D., Dorofeeva, I., Ensina, L. F., Ertas, R., Ferrucci, S. M., Figueras-Nart, I., Fomina, D., Franken, S. M., Fukunaga, A., Gimenez-Arnau, A. M., Godse, K., Goncalo, M., Gotua, M., Grattan, C., Guillet, C., Inomata, N., Jakob, T., Karakaya, G., Kasperska-Zajac, A., Katelaris, C. H., Kosnik, M., Krasowska, D., Kulthanan, K., Kumaran, M. S., Lang, C., Larco-Sousa, J. I., Lazaridou, E., Leslie, T. A., Lippert, U., Llosa, O. C., Makris, M., Marsland, A., Medina, I. V., Meshkova, R., Palitot, E. B., Parisi, C. A. S., Pickert, J., Ramon, G. D., Rodriguez-Gonzalez, M., Rosario, N., Rudenko, M., Rutkowski, K., Sanchez, J., Schliemann, S., Sekerel, B. E., Serpa, F. S., Serra-Baldrich, E., Song, Z. Q., Soria, A., Staevska, M., Staubach, P., Tagka, A., Takahagi, S., Thomsen, S. F., Treudler, R., Vadasz, Z., Valle, S. O. R., Van Doorn, M. B. A., Vestergaard, C., Wagner, N., Wang, D. H., Wang, L. C., Wedi, B., Xepapadaki, P., Yücel, E., Zalewska-Janowska, A., Zhao, Z. T., Zuberbier, T., Maurer, M., School of Medicine, AII - Infectious diseases, Kocaturk, Emek, Salman, Andac, Cherrez-Ojeda, Ivan, Criado, Paulo Ricardo, Peter, Jonny, Comert-Ozer, Elif, Abuzakouk, Mohamed, Agondi, Rosana Camara, Al-Ahmad, Mona, Altrichter, Sabine, Arnaout, Rand, Arruda, Luisa Karla, Asero, Riccardo, Bauer, Andrea, Ben-Shoshan, Moshe, Bernstein, Jonathan A., Bizjak, Mojca, Boccon-Gibod, Isabelle, Bonnekoh, Hanna, Bouillet, Laurence, Brzoza, Zenon, Busse, Paula, Campos, Regis A., Carne, Emily, Conlon, Niall, Criado, Roberta F., de Souza Lima, Eduardo M., Demir, Semra, Dissemond, Joachim, Gunaydin, Sibel Dogan, Dorofeeva, Irina, Ensina, Luis Felipe, Ertas, Ragip, Ferrucci, Silvia Mariel, Figueras-Nart, Ignasi, Fomina, Daria, Franken, Sylvie M., Fukunaga, Atsushi, Gimenez-Arnau, Ana M., Godse, Kiran, Goncalo, Margarida, Gotua, Maia, Grattan, Clive, Guillet, Carole, Inomata, Naoko, Jakob, Thilo, Karakaya, Gul, Kasperska-Zajac, Alicja, Katelaris, Constance H., Kosnik, Mitja, Krasowska, Dorota, Kulthanan, Kanokvalai, Kumaran, M. Sendhil, Lang, Claudia, Ignacio Larco-Sousa, Jose, Lazaridou, Elisavet, Leslie, Tabi Anika, Lippert, Undine, Llosa, Oscar Calderon, Makris, Michael, Marsland, Alexander, Medina, Iris, V, Meshkova, Raisa, Palitot, Esther Bastos, Parisi, Claudio A. S., Pickert, Julia, Ramon, German D., Rodriguez-Gonzalez, Monica, Rosario, Nelson, Rudenko, Michael, Rutkowski, Krzysztof, Sanchez, Jorge, Schliemann, Sibylle, Sekerel, Bulent Enis, Serpa, Faradiba S., Serra-Baldrich, Esther, Song, Zhiqiang, Soria, Angele, Staevska, Maria, Staubach, Petra, Tagka, Anna, Takahagi, Shunsuke, Thomsen, Simon Francis, Treudler, Regina, Vadasz, Zahava, Rodrigues Valle, Solange Oliveira, Van Doorn, Martijn B. A., Vestergaard, Christian, Wagner, Nicola, Wang, Dahu, Wang, Liangchun, Wedi, Bettina, Xepapadaki, Paraskevi, Yucel, Esra, Zalewska-Janowska, Anna, Zhao, Zuotao, Zuberbier, Torsten, and Maurer, Marcus

Subjects
Male, 0301 basic medicine, STRESS, Exacerbation, UCARE, pandemije, Medizin, Omalizumab, SERUM, chronic urticaria, 0302 clinical medicine, Pandemic, Health care, Immunology and Allergy, Chronic Urticaria, treatment, Chronic urticaria, COVID-19, Cyclosporine, SARS-CoV-2, Treatment, zdravljenje, ASSOCIATION, Middle Aged, cyclosporine, omalizumab, pandemic, kronična urtikarija, INFECTIONS, GA(2)LEN, Female, 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit, medicine.drug, Adult, medicine.medical_specialty, Adolescent, Coronavirus disease 2019 (COVID-19), Immunology, udc:616-097, pandemics, ciklosporin, Young Adult, 03 medical and health sciences, Patient referral, medicine, Humans, In patient, Patient Reported Outcome Measures, Aged, Internet, business.industry, DEFINITION, Medicine, Allergy, Cross-Sectional Studies, 030104 developmental biology, 030228 respiratory system, Emergency medicine, business
Abstract

Introduction: the COVID-19 pandemic dramatically disrupts health care around the globe. The impact of the pandemic on chronic urticaria (CU) and its management are largely unknown. Aim: to understand how CU patients are affected by the COVID-19 pandemic; how specialists alter CU patient management; and the course of CU in patients with COVID-19. Materials and methods: our cross-sectional, international, questionnaire-based, multicenter UCARE COVID-CU study assessed the impact of the pandemic on patient consultations, remote treatment, changes in medications, and clinical consequences. Results: the COVID-19 pandemic severely impairs CU patient care, with less than 50% of the weekly numbers of patients treated as compared to before the pandemic. Reduced patient referrals and clinic hours were the major reasons. Almost half of responding UCARE physicians were involved in COVID-19 patient care, which negatively impacted on the care of urticaria patients. The rate of face-to-face consultations decreased by 62%, from 90% to less than half, whereas the rate of remote consultations increased by more than 600%, from one in 10 to more than two thirds. Cyclosporine and systemic corticosteroids, but not antihistamines or omalizumab, are used less during the pandemic. CU does not affect the course of COVID-19, but COVID-19 results in CU exacerbation in one of three patients, with higher rates in patients with severe COVID-19. Conclusions: the COVID-19 pandemic brings major changes and challenges for CU patients and their physicians. The long-term consequences of these changes, especially the increased use of remote consultations, require careful evaluation., Novartis; Sanofi; Menarini Universidad Espiritu Santo; Takeda; Allakos; AstraZeneca; CSL Behring; Genentech; Pharming; GSK; Shire/Takada; BioCryst; ResTORbio; Pearl Therapeutics, CVS Health; Law offices of Levin; Riback; Adelman; Flangel; Vedder Price; Fresenius; Taiho; Kyowa Kirin; Tanabe; Korin; Uriach Pharma; Instituto Carlos III FEDER; Menarini; Amgen; Thermo Fisher; Avene; ALK‐Abello; Bencard/Allergy Therapeutics; Celgene; Allergopharma; Faes Farma; AbbVie; Janssen; Leo Pharma; Lilly; Roche; Genesis; Menlo Therapeutics; UCB; Pfizer; Almirall; Galderma; Allergika; Beiersdorf; Biocryst; Biogen Idec; BMS; Boehringer‐Ingelheim; Eli‐Lilly; Galderma; Hexal; Klosterfrau; LEO‐Pharma; LETI‐Pharma; L´Oreal; Medice; Octapharma; Pflüger; Pharming; Regeneron; Shire; ALK‐Abello; Fraunhofer‐IZI Leipzig; Hautnetz Leipzig/Westsachsen; MSD; HAL‐Allergy; Bencard; Nestle; Nutricia; Bayer Health Care; FAES; Henkel; Allakos; Argenx; Genentech Menarini; Moxie; Aralez; Celldex

Published
2021

13. Chemokines and mast cells

Author

Krüger-Krasagakes, Sabine, Grützkau, Andreas, Lippert, Undine, Henz, Beate M., Parnham, Michael J., editor, Kownatzki, Eckhard, editor, and Norgauer, Johannes, editor

Published
1998
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15. Polymorphisms in the mitochondrially encoded ATP synthase 8 gene are associated with susceptibility to bullous pemphigoid in the German population

Author

Hirose, Misa, Schilf, Paul, Benoit, Sandrine, Eming, Rüdiger, Gläser, Regine, Homey, Bernhard, Kunz, Manfred, Nebel, Almut, Peitsch, Wiebke K., Pföhler, Claudia, Sárdy, Miklós, Schreiber, Stefan, Zillikens, Detlef, Schmidt, Enno, Ibrahim, Saleh M., Däschlein, Georg, Goebeler, Matthias, Goetze, Steven, Günther, Claudia, Hadaschik, Eva, Hunzelmann, Nicolas, Kreuter, Alexander, Lippert, Undine, Sticherling, Michael, and Worm, Margitta

Published
2015
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20. Expertenkonsensus zu praxisrelevanten Aspekten bei der Behandlung der chronischen Urtikaria

Author

Bauer, Andrea, primary, Dickel, Heinrich, additional, Jakob, Thilo, additional, Kleinheinz, Andreas, additional, Lippert, Undine, additional, Metz, Martin, additional, Schliemann, Sibylle, additional, Schwichtenberg, Uwe, additional, Staubach, Petra, additional, Valesky, Eva, additional, Wagner, Nicola, additional, Wedi, Bettina, additional, and Maurer, Marcus, additional

Published
2021
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21. The global impact of the COVID‐19 pandemic on the management and course of chronic urticaria

Author

Kocatürk, Emek, primary, Salman, Andaç, additional, Cherrez‐Ojeda, Ivan, additional, Criado, Paulo Ricardo, additional, Peter, Jonny, additional, Comert‐Ozer, Elif, additional, Abuzakouk, Mohamed, additional, Agondi, Rosana Câmara, additional, Al‐Ahmad, Mona, additional, Altrichter, Sabine, additional, Arnaout, Rand, additional, Arruda, Luisa Karla, additional, Asero, Riccardo, additional, Bauer, Andrea, additional, Ben‐Shoshan, Moshe, additional, Bernstein, Jonathan A., additional, Bizjak, Mojca, additional, Boccon‐Gibod, Isabelle, additional, Bonnekoh, Hanna, additional, Bouillet, Laurence, additional, Brzoza, Zenon, additional, Busse, Paula, additional, Campos, Regis A, additional, Carne, Emily, additional, Conlon, Niall, additional, Criado, Roberta F., additional, de Souza Lima, Eduardo M., additional, Demir, Semra, additional, Dissemond, Joachim, additional, Doğan Günaydın, Sibel, additional, Dorofeeva, Irina, additional, Ensina, Luis Felipe, additional, Ertaş, Ragıp, additional, Ferrucci, Silvia Mariel, additional, Figueras‐Nart, Ignasi, additional, Fomina, Daria, additional, Franken, Sylvie M, additional, Fukunaga, Atsushi, additional, Giménez‐Arnau, Ana M., additional, Godse, Kiran, additional, Gonçalo, Margarida, additional, Gotua, Maia, additional, Grattan, Clive, additional, Guillet, Carole, additional, Inomata, Naoko, additional, Jakob, Thilo, additional, Karakaya, Gul, additional, Kasperska‐Zając, Alicja, additional, Katelaris, Constance H, additional, Košnik, Mitja, additional, Krasowska, Dorota, additional, Kulthanan, Kanokvalai, additional, Kumaran, M. Sendhil, additional, Lang, Claudia, additional, Larco‐Sousa, José Ignacio, additional, Lazaridou, Elisavet, additional, Leslie, Tabi Anika, additional, Lippert, Undine, additional, llosa, Oscar Calderón, additional, Makris, Michael, additional, Marsland, Alexander, additional, Medina, Iris V., additional, Meshkova, Raisa, additional, Palitot, Esther Bastos, additional, Parisi, Claudio A.S., additional, Pickert, Julia, additional, Ramon, German D., additional, Rodríguez‐Gonzalez, Mónica, additional, Rosario, Nelson, additional, Rudenko, Michael, additional, Rutkowski, Krzysztof, additional, Sánchez, Jorge, additional, Schliemann, Sibylle, additional, Sekerel, Bulent Enis, additional, Serpa, Faradiba S., additional, Serra‐Baldrich, Esther, additional, Song, Zhiqiang, additional, Soria, Angèle, additional, Staevska, Maria, additional, Staubach, Petra, additional, Tagka, Anna, additional, Takahagi, Shunsuke, additional, Thomsen, Simon Francis, additional, Treudler, Regina, additional, Vadasz, Zahava, additional, Valle, Solange Oliveira Rodrigues, additional, Van Doorn, Martijn B.A., additional, Vestergaard, Christian, additional, Wagner, Nicola, additional, Wang, Dahu, additional, Wang, Liangchun, additional, Wedi, Bettina, additional, Xepapadaki, Paraskevi, additional, Yücel, Esra, additional, Zalewska‐Janowska, Anna, additional, Zhao, Zuotao, additional, Zuberbier, Torsten, additional, and Maurer, Marcus, additional

Published
2020
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32. Recommendations for the use of rituximab (anti-CD20 antibody) in the treatment of autoimmune bullous skin diseases

Author

Hertl, Michael, Zillikens, Detlef, Borradori, Luca, Bruckner-Tuderman, Leena, Burckhard, Harald, Eming, Rüdiger, Engert, Andreas, Goebeler, Matthias, Hofmann, Silke, Hunzelmann, Nicolas, Karlhofer, Franz, Kautz, Ocko, Lippert, Undine, Niedermeier, Andrea, Nitschke, Martin, Pfütze, Martin, Reiser, Marcel, Rose, Christian, Schmidt, Enno, Shimanovich, Iakov, Sticherling, Michael, and Wolff-Franke, Sonja

Published
2008

33. Empfehlungen für den Einsatz von Rituximab (anti-CD20-Antikörper) bei bullösen Autoimmundermatosen

Author

Hertl, Michael, Zillikens, Detlef, Borradori, Luca, Bruckner-Tuderman, Leena, Burckhard, Harald, Eming, Rüdiger, Engert, Andreas, Goebeler, Matthias, Hofmann, Silke, Hunzelmann, Nicolas, Karlhofer, Franz, Kautz, Ocko, Lippert, Undine, Niedermeier, Andrea, Nitschke, Martin, Pfütze, Martin, Reiser, Marcel, Rose, Christian, Schmidt, Enno, Shimanovich, Iakov, Sticherling, Michael, and Wolff-Franke, Sonja

Published
2008

45. Disseminated refractory pyoderma gangraenosumduring an ulcerative colitis flare. Treatment with infliximab.

Author

Zampeli, Vasiliki A., Lippert, Undine, Nikolakis, Georgios, Makrantonaki, Evgenia, Tzellos, Thrasivoulos G., Krause, Ulf, and Zouboulis, Christos C.

Subjects
*PYODERMA gangrenosum, *ULCERATIVE colitis, *INFLIXIMAB, *IMMUNE response, *INFLAMMATION, *ETIOLOGY of diseases
Abstract

Background: Pyoderma gangraenosum is an immune-mediated, inflammatory, neutrophilic dermatosis of unknown etiology, which represents one of the extraintestinal manifestations of inflammatory bowel disease. It is a rare disease that occurs in less than 1% of patients with inflammatory bowel disease and with the same ratio in patients with Crohn's disease and ulcerative colitis. Main observations: A 36-year-old woman was diagnosed with ulcerative colitis 6 years before admission to our dermatology department with an acute disseminated pyoderma gangraenosum with mucosal involvement, during a flare of ulcerative colitis. Disease progression was interrupted by intravenous administration of the tumor necrosis factor-α inhibitor infliximab at 5mg/kg at weeks 0, 2, and 6 (1st cycle) and every 8 weeks thereafter. Improvement of intestinal, skin and oral manifestations was evident already after the 1st cycle of treatment and has been maintained since (at least 16 months). Conclusions: This case report is one of very few on disseminated pyoderma gangraenosum with oral involvement complicating ulcerative colitis, where infliximab was shown to have a rapid efficacy on skin, mucosal and bowel symptoms. [ABSTRACT FROM AUTHOR]

Published
2015
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