1. Deaths in children and adolescents associated with COVID-19 and MIS-C in the United States
- Author
-
Mojisola Ojo, Julie Hand, Heather Venkat, John J. Openshaw, Gillian Richardson, Kelly White, David A. Siegel, Danae Bixler, Talia Pindyck, Megan Gumke, LaTonia Clay Richardson, Ali Garcia, Breanna Kawasaki, Anna-Kathryn Burch, Maura K. Lash, Laura J Viens, Quan M. Vu, Judy Kauerauf, Laurel Harduar-Morano, Paul R. Young, Ellen H. Lee, Sietske de Fijter, Andrea Leapley, Bree Barbeau, Hannah G. Rosenblum, Sarah Reagan-Steiner, Carolyn V. Gould, Ozair Naqvi, Kim Kirkey, Anne Kimball, Jonathan Kolsin, Melissa Tobin-D’Angelo, Stephen J. Pont, Alan J. Siniscalchi, Ariela Zamcheck, Ken Komatsu, Linnea Larson, Emilia H. Koumans, Paul Byers, Farah Ahmed, Erica Wilson, Kathleen H. Reilly, Heather Reid, Adele Lewis, and David W. McCormick
- Subjects
Male ,2019-20 coronavirus outbreak ,Pediatrics ,medicine.medical_specialty ,Demographics ,Coronavirus disease 2019 (COVID-19) ,Adolescent ,medicine.medical_treatment ,Ethnic group ,Article ,medicine ,Humans ,Acute respiratory failure ,Child ,Asthma ,Retrospective Studies ,Mechanical ventilation ,business.industry ,COVID-19 ,Infant ,medicine.disease ,Obesity ,Systemic Inflammatory Response Syndrome ,United States ,Child, Preschool ,Pediatrics, Perinatology and Child Health ,Female ,business - Abstract
OBJECTIVES To describe the demographics, clinical characteristics, and hospital course among persons METHODS We conducted a retrospective case series of suspected SARS-CoV-2-associated deaths in the United States in persons RESULTS We included 112 SARS-CoV-2-associated deaths from 25 participating jurisdictions. The median age was 17 years (IQR 8.5–19 years). Most decedents were male (71, 63%), 31 (28%) were Black (non-Hispanic) persons, and 52 (46%) were Hispanic persons. Ninety-six decedents (86%) had at least 1 underlying condition; obesity (42%), asthma (29%), and developmental disorders (22%) were most commonly documented. Among 69 hospitalized decedents, common complications included mechanical ventilation (75%) and acute respiratory failure (82%). The sixteen (14%) decedents who met multisystem inflammatory syndrome in children (MIS-C) criteria were similar in age, sex, and race and/or ethnicity to decedents without MIS-C; 11 of 16 (69%) had at least 1 underlying condition. CONCLUSIONS SARS-CoV-2-associated deaths among persons
- Published
- 2021