935 results on '"Linke, Wolfgang A."'
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2. Fast myosin binding protein C knockout in skeletal muscle alters length-dependent activation and myofilament structure
3. Myosin-binding protein C regulates the sarcomere lattice and stabilizes the OFF states of myosin heads
4. Titin governs myocardial passive stiffness with major support from microtubules and actin and the extracellular matrix
5. The dynamics of the endothelial glycocalyx: a rare snapshot by electron microscopy
6. Impaired Intracellular Calcium Buffering Contributes to the Arrhythmogenic Substrate in Atrial Myocytes From Patients With Atrial Fibrillation
7. Titin force in muscle cells alters lattice order, thick and thin filament protein formation
8. Molecular Characterisation of Titin N2A and Its Binding of CARP Reveals a Titin/Actin Cross-linking Mechanism
9. An isoform of the giant protein titin is a master regulator of human T lymphocyte trafficking
10. Stretching the story of titin and muscle function
11. Acetylation and phosphorylation changes to cardiac proteins in experimental HFpEF due to metabolic risk reveal targets for treatment
12. The distinctive mechanical and structural signatures of residual force enhancement in myofibers.
13. Modulatorische Einheiten bei Herzinsuffizienz: Vorstellung des Sonderforschungsbereichs 1002 (SFB 1002)
14. Mechanisms of myocardial reverse remodelling and its clinical significance: A scientific statement of the ESC Working Group on Myocardial Function
15. Virtually “muscling” in pandemic: first virtual European Muscle Conference (September 20–22, 2021)
16. Regulation of titin-based cardiac stiffness by unfolded domain oxidation (UnDOx)
17. Protein phosphatase 5 regulates titin phosphorylation and function at a sarcomere-associated mechanosensor complex in cardiomyocytes.
18. Functional characterization of novel alpha-helical rod domain desmin (DES) pathogenic variants associated with dilated cardiomyopathy, atrioventricular block and a risk for sudden cardiac death
19. Imaging of Existing and Newly Translated Proteins Elucidates Mechanisms of Sarcomere Turnover.
20. Symmetric dimethylarginine in dysfunctional high-density lipoprotein mediates endothelial glycocalyx breakdown in chronic kidney disease
21. BMI-Stratified Exploration of the ‘Obesity Paradox’: Heart Failure Perspectives from a Large German Insurance Database
22. Mechanisms of myocardial reverse remodelling and its clinical significance: A scientific statement of the ESC Working Group on Myocardial Function
23. Overexpression of human BAG3P209L in mice causes restrictive cardiomyopathy
24. The Translational Landscape of the Human Heart
25. A novel isoform of myosin 18A (Myo18Aγ) is an essential sarcomeric protein in mouse heart
26. SPRED2 deficiency elicits cardiac arrhythmias and premature death via impaired autophagy
27. Titin-based force regulates cardiac myofilament structures mediating length-dependent activation
28. Alterations in Titin Properties and Myocardial Fibrosis Correlate With Clinical Phenotypes in Hemodynamic Subgroups of Severe Aortic Stenosis
29. Fast myosin binding protein C knockout in skeletal muscle alters length-dependent activation and myofilament structure
30. Impaired Cardiac and Skeletal Muscle Energetics Following Anthracycline Therapy for Breast Cancer
31. Acute heart failure: mechanisms and pre-clinical models—a Scientific Statement of the ESC Working Group on Myocardial Function
32. Myosin-binding protein C forms C-links and stabilizes OFF states of myosin
33. Imaging of existing and newly translated proteins elucidates mechanisms of sarcomere turnover
34. Damped Elastic Recoil of the Titin Spring in Myofibrils of Human Myocardium
35. Severe DCM phenotype of patient harboring RBM20 mutation S635A can be modeled by patient-specific induced pluripotent stem cell-derived cardiomyocytes
36. The first versatile human iPSC-based model of ectopic virus induction allows new insights in RNA-virus disease
37. Homozygous expression of the myofibrillar myopathy-associated p.W2710X filamin C variant reveals major pathomechanisms of sarcomeric lesion formation
38. A HaloTag-TEV genetic cassette for mechanical phenotyping of proteins from tissues
39. Differentiation- and Stress-Dependent Nuclear Cytoplasmic Redistribution of Myopodin, a Novel Actin-Bundling Protein
40. Kettin, a Major Source of Myofibrillar Stiffness in Drosophila Indirect Flight Muscle
41. Titin takes centerstage among cytoskeletal contributions to myocardial passive stiffness.
42. I-Band Titin in Cardiac Muscle Is a Three-Element Molecular Spring and Is Critical for Maintaining Thin Filament Structure
43. Nature of PEVK-Titin Elasticity in Skeletal Muscle
44. Stretch Harmonizes Sarcomere Strain Across the Cardiomyocyte
45. Novel Filamin C Myofibrillar Myopathy Variants Cause Different Pathomechanisms and Alterations in Protein Quality Systems
46. Animal models and animal-free innovations for cardiovascular research
47. Myocardial Microvascular Inflammatory Endothelial Activation in Heart Failure With Preserved Ejection Fraction
48. Functional characterization of the novel DES mutation p.L136P associated with dilated cardiomyopathy reveals a dominant filament assembly defect
49. Troponin destabilization impairs sarcomere-cytoskeleton interactions in iPSC-derived cardiomyocytes from dilated cardiomyopathy patients
50. Cronos Titin Is Expressed in Human Cardiomyocytes and Necessary for Normal Sarcomere Function
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