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17 results on '"Linillos-Pradillo, Beatriz"'

4. Integrando a la inteligencia artificial como herramienta didáctica

Author

Rancan, Lisa, Sebastían Serrano, Alvaro, Vazquéz Pérez, Patricia, Ordoñez Gutierrez, Lara, Herranz Martín, Saul, Linillos Pradillo, Beatriz, Marea Peñalver, Salomón, Rancan, Lisa, Sebastían Serrano, Alvaro, Vazquéz Pérez, Patricia, Ordoñez Gutierrez, Lara, Herranz Martín, Saul, Linillos Pradillo, Beatriz, and Marea Peñalver, Salomón

Published
2024

8. High throughput LC-MS/MS method for steroid hormone analysis in rat liver and plasma – unraveling methodological challenges

Author

Evangelista, Sara, primary, Vazakidou, Paraskevi, additional, Koekkoek, Jacco, additional, Heinzelmann, Manuel T., additional, Lichtensteiger, Walter, additional, Schlumpf, Margret, additional, Tresguerres, Jesus A.F., additional, Linillos-Pradillo, Beatriz, additional, van Duursen, Majorie B.M., additional, Lamoree, Marja H., additional, and Leonards, Pim E.G., additional

Published
2023
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13. Clima Educativo en Medicina: Oportunidades de Mejora

Author

Vara Ameigeiras, Elena Mª, Arias Díaz, Javier, Alonso González, Alberto, Bourquia, Marwane, Corrales Fernández, Carmen, Garcia Marin, Mª Cruz, Garutti Martínez, Ignacio, Giner Nogueras, Manuel, Gutierrez-Vierna, Mª Elvira, Idrissi, Hassana, Linillos Pradillo, Beatriz, Millán Núñez Cortés, Jesús, Paredes Royano, Sergio Damián, Rancan, Lisa, Simón Adiego, Carlos Mª, Valdés López-Linares, Sergio, Zueco Alegre, José Antonio, Vara Ameigeiras, Elena Mª, Arias Díaz, Javier, Alonso González, Alberto, Bourquia, Marwane, Corrales Fernández, Carmen, Garcia Marin, Mª Cruz, Garutti Martínez, Ignacio, Giner Nogueras, Manuel, Gutierrez-Vierna, Mª Elvira, Idrissi, Hassana, Linillos Pradillo, Beatriz, Millán Núñez Cortés, Jesús, Paredes Royano, Sergio Damián, Rancan, Lisa, Simón Adiego, Carlos Mª, Valdés López-Linares, Sergio, and Zueco Alegre, José Antonio

Abstract

El entorno donde se desarrolla la formación, las relaciones alumno-profesor, los aspectos físicos (facultad/hospital) como hábitat, etc. es percibido por los alumnos influyendo en su comportamiento y lo determinan de forma importante, condicionando la consecución de los objetivos, la satisfacción y el éxito. Si el entorno educativo no es adecuado, se dificulta la adquisición de conocimientos y/o de valores de los futuros profesionales y las facultades de medicina deben reflexionar seriamente para aplicar los cambios necesarios para mejorar la enseñanza. En la enseñanza, tan importante es establecer un contexto o clima para el aprendizaje adecuado, como impartir conocimientos o compartir experiencias. Se propone identificar las deficiencias, es decir, los aspectos críticos del clima de aprendizaje como base para las medidas de optimización, así como las fortalezas de un currículo o plan de estudios. Observar las expectativas de los estudiantes con las actuales experiencias, para identificar puntos que requieran mejoras y comparar el ambiente de aprendizaje en diferentes lugares y etapas, entre los estudiantes de los diferentes cursos del Grado en Medicina de la Universidad Complutense de Madrid.

Published
2022

14. A Novel Circulating Noncoding Small RNA for the Detection of Acute Myocarditis

Author

Blanco-Domínguez, Rafael, primary, Sánchez-Díaz, Raquel, additional, de la Fuente, Hortensia, additional, Jiménez-Borreguero, Luis J., additional, Matesanz-Marín, Adela, additional, Relaño, Marta, additional, Jiménez-Alejandre, Rosa, additional, Linillos-Pradillo, Beatriz, additional, Tsilingiri, Katerina, additional, Martín-Mariscal, María L., additional, Alonso-Herranz, Laura, additional, Moreno, Guillermo, additional, Martín-Asenjo, Roberto, additional, García-Guimaraes, Marcos M., additional, Bruno, Katelyn A., additional, Dauden, Esteban, additional, González-Álvaro, Isidoro, additional, Villar-Guimerans, Luisa M., additional, Martínez-León, Amaia, additional, Salvador-Garicano, Ane M., additional, Michelhaugh, Sam A., additional, Ibrahim, Nasrien E., additional, Januzzi, James L., additional, Kottwitz, Jan, additional, Iliceto, Sabino, additional, Plebani, Mario, additional, Basso, Cristina, additional, Baritussio, Anna, additional, Seguso, Mara, additional, Marcolongo, Renzo, additional, Ricote, Mercedes, additional, Fairweather, DeLisa, additional, Bueno, Héctor, additional, Fernández-Friera, Leticia, additional, Alfonso, Fernando, additional, Caforio, Alida L.P., additional, Pascual-Figal, Domingo A., additional, Heidecker, Bettina, additional, Lüscher, Thomas F., additional, Das, Saumya, additional, Fuster, Valentín, additional, Ibáñez, Borja, additional, Sánchez-Madrid, Francisco, additional, and Martín, Pilar, additional

Published
2021
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16. Thymus-Derived Regulatory T Cell Development Is Regulated by C-Type Lectin-Mediated BIC/MicroRNA 155 Expression

Author

Sánchez-Díaz, Raquel, primary, Blanco-Dominguez, Rafael, additional, Lasarte, Sandra, additional, Tsilingiri, Katerina, additional, Martín-Gayo, Enrique, additional, Linillos-Pradillo, Beatriz, additional, de la Fuente, Hortensia, additional, Sánchez-Madrid, Francisco, additional, Nakagawa, Rinako, additional, Toribio, María L., additional, and Martín, Pilar, additional

Published
2017
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17. A Novel Circulating MicroRNA for the Detection of Acute Myocarditis.

Author

Blanco-Domínguez R, Sánchez-Díaz R, de la Fuente H, Jiménez-Borreguero LJ, Matesanz-Marín A, Relaño M, Jiménez-Alejandre R, Linillos-Pradillo B, Tsilingiri K, Martín-Mariscal ML, Alonso-Herranz L, Moreno G, Martín-Asenjo R, García-Guimaraes MM, Bruno KA, Dauden E, González-Álvaro I, Villar-Guimerans LM, Martínez-León A, Salvador-Garicano AM, Michelhaugh SA, Ibrahim NE, Januzzi JL, Kottwitz J, Iliceto S, Plebani M, Basso C, Baritussio A, Seguso M, Marcolongo R, Ricote M, Fairweather D, Bueno H, Fernández-Friera L, Alfonso F, Caforio ALP, Pascual-Figal DA, Heidecker B, Lüscher TF, Das S, Fuster V, Ibáñez B, Sánchez-Madrid F, and Martín P

Subjects
Animals, Autoimmune Diseases genetics, Autoimmune Diseases metabolism, Biomarkers blood, CD4 Antigens, Diagnosis, Differential, Disease Models, Animal, Humans, Mice, Mice, Inbred BALB C, Mice, Knockout, Myocarditis genetics, Polymerase Chain Reaction, ROC Curve, T-Lymphocytes immunology, T-Lymphocytes metabolism, Th17 Cells metabolism, Circulating MicroRNA blood, MicroRNAs blood, Myocardial Infarction diagnosis, Myocarditis diagnosis
Abstract

Background: The diagnosis of acute myocarditis typically requires either endomyocardial biopsy (which is invasive) or cardiovascular magnetic resonance imaging (which is not universally available). Additional approaches to diagnosis are desirable. We sought to identify a novel microRNA for the diagnosis of acute myocarditis., Methods: To identify a microRNA specific for myocarditis, we performed microRNA microarray analyses and quantitative polymerase-chain-reaction (qPCR) assays in sorted CD4+ T cells and type 17 helper T (Th17) cells after inducing experimental autoimmune myocarditis or myocardial infarction in mice. We also performed qPCR in samples from coxsackievirus-induced myocarditis in mice. We then identified the human homologue for this microRNA and compared its expression in plasma obtained from patients with acute myocarditis with the expression in various controls., Results: We confirmed that Th17 cells, which are characterized by the production of interleukin-17, are a characteristic feature of myocardial injury in the acute phase of myocarditis. The microRNA mmu-miR-721 was synthesized by Th17 cells and was present in the plasma of mice with acute autoimmune or viral myocarditis but not in those with acute myocardial infarction. The human homologue, designated hsa-miR-Chr8:96, was identified in four independent cohorts of patients with myocarditis. The area under the receiver-operating-characteristic curve for this novel microRNA for distinguishing patients with acute myocarditis from those with myocardial infarction was 0.927 (95% confidence interval, 0.879 to 0.975). The microRNA retained its diagnostic value in models after adjustment for age, sex, ejection fraction, and serum troponin level., Conclusions: After identifying a novel microRNA in mice and humans with myocarditis, we found that the human homologue (hsa-miR-Chr8:96) could be used to distinguish patients with myocarditis from those with myocardial infarction. (Funded by the Spanish Ministry of Science and Innovation and others.)., (Copyright © 2021 Massachusetts Medical Society.)

Published
2021
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