2,555 results on '"Lindsley, Craig W."'
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2. Activation of Metabotropic Glutamate Receptor 3 Modulates Thalamo-accumbal Transmission and Rescues Schizophrenia-Like Physiological and Behavioral Deficits
3. Development of a Peripherally Restricted 5-HT2B Partial Agonist for Treatment of Pulmonary Arterial Hypertension
4. Selective M5 muscarinic acetylcholine receptor negative allosteric modulator VU6008667 blocks acquisition of opioid self-administration
5. Confronting Racism in Chemistry Journals
6. Update to Our Reader, Reviewer, and Author CommunitiesApril 2020
7. Update to Our Reader, Reviewer, and Author Communities-April 2020.
8. mGlu1-mediated restoration of prefrontal cortex inhibitory signaling reverses social and cognitive deficits in an NMDA hypofunction model in mice
9. Clinical and Preclinical Evidence for M1 Muscarinic Acetylcholine Receptor Potentiation as a Therapeutic Approach for Rett Syndrome
10. Computer-Aided Design and Biological Evaluation of Diazaspirocyclic D4R Antagonists
11. Rational Molecular Editing: A New Paradigm in Drug Discovery.
12. Rapid sp3-Enriched Scaffold Generation via a Selective Aziridine Amide Ring-Opening Reaction
13. mGlu1 potentiation enhances prelimbic somatostatin interneuron activity to rescue schizophrenia-like physiological and cognitive deficits
14. Discovery and characterization of VU0542270, the first selective inhibitor of vascular Kir6.1/SUR2B KATPchannels
15. Evaluation of the Indazole Analogs of 5-MeO-DMT and Related Tryptamines as Serotonin Receptor 2 Agonists
16. Crystal structure of the M₅ muscarinic acetylcholine receptor
17. Call for Papers: Fungal Pathogens – Life Cycle, Infection, Host Immunity and Drug Discovery
18. Diagnostic and Therapeutic Radiopharmaceuticals: A “Hot” Topic
19. Call for Papers: Natural Products Driven Medicinal Chemistry
20. Development of Potent and Selective Negative Allosteric Modulators of the Metabotropic Glutamate Receptor 2 for the Potential Treatment of Alzheimer’s Disease
21. Activation of metabotropic glutamate receptor 3 modulates thalamo-accumbal transmission and rescues schizophrenia-like physiological and behavioral deficits.
22. The M4 muscarinic acetylcholine receptor positive allosteric modulator VU0467154 normalizes non‐rapid eye movement sleep deficits in non‐pathologically aged mice.
23. Modulation of arousal and sleep/wake architecture by M1 PAM VU0453595 across young and aged rodents and nonhuman primates
24. Activation of the mGlu1 metabotropic glutamate receptor has antipsychotic-like effects and is required for efficacy of M4 muscarinic receptor allosteric modulators
25. Competition and allostery govern substrate selectivity of cyclooxygenase-2
26. Molecular Skeleton Editing for New Drug Discovery.
27. M1 Muscarinic Receptors Modulate Fear-Related Inputs to the Prefrontal Cortex: Implications for Novel Treatments of Posttraumatic Stress Disorder
28. Rapid sp3‑Enriched Scaffold Generation via a Selective Aziridine Amide Ring-Opening Reaction.
29. In Memory of Professor Hualiang Jiang
30. Development of a Selective and High Affinity Radioligand, [3H]VU6013720, for the M4Muscarinic Receptor
31. 2B Determined: The Future of the Serotonin Receptor 2B in Drug Discovery
32. Call for Papers: Medicinal Chemistry of Next Generation Vaccine Adjuvants
33. Metabotropic glutamate receptor subtype 3 gates acute stress-induced dysregulation of amygdalo-cortical function
34. Virtual Special Issue: New Drug Modalities in Medicinal Chemistry, Pharmacology, and Translational Science
35. Pharmacological hallmarks of allostery at the M4 muscarinic receptor elucidated through structure and dynamics
36. Development of the first vascular-specific KATP channel inhibitor for the treatment of patent ductus arteriosus in newborns
37. Synthesis and SAR of a novel Kir6.2/SUR1 channel opener scaffold identified by HTS
38. Lipophilicity
39. mGlu1 and mGlu5 modulate distinct excitatory inputs to the nucleus accumbens shell
40. M1-positive allosteric modulators lacking agonist activity provide the optimal profile for enhancing cognition
41. Muscarinic M5 receptors modulate ethanol seeking in rats
42. Data from Inhibition of Mammalian Target of Rapamycin Is Required for Optimal Antitumor Effect of HER2 Inhibitors against HER2-Overexpressing Cancer Cells
43. Supplementary Data from Inhibition of Mammalian Target of Rapamycin Is Required for Optimal Antitumor Effect of HER2 Inhibitors against HER2-Overexpressing Cancer Cells
44. Data from Loss of Phosphatase and Tensin Homologue Deleted on Chromosome 10 Engages ErbB3 and Insulin-Like Growth Factor-I Receptor Signaling to Promote Antiestrogen Resistance in Breast Cancer
45. Supplementary Figures 1-8 from Loss of Phosphatase and Tensin Homologue Deleted on Chromosome 10 Engages ErbB3 and Insulin-Like Growth Factor-I Receptor Signaling to Promote Antiestrogen Resistance in Breast Cancer
46. Supplementary Methods from Loss of Phosphatase and Tensin Homologue Deleted on Chromosome 10 Engages ErbB3 and Insulin-Like Growth Factor-I Receptor Signaling to Promote Antiestrogen Resistance in Breast Cancer
47. The Importance of PK–PD
48. Identification of Potent, Selective, and Peripherally Restricted Serotonin Receptor 2B Antagonists from a High-Throughput Screen
49. Effects of muscarinic M1 and M4 acetylcholine receptor stimulation on extinction and reinstatement of cocaine seeking in male mice, independent of extinction learning
50. Ventral Tegmental Area M5 Muscarinic Receptors Mediate Effort-Choice Responding and Nucleus Accumbens Dopamine in a Sex-Specific Manner
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