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2. The Association between Sickle Cell Disease and Postpartum Severe Maternal Morbidity.

Author

Poliektov, Natalie E., Vuncannon, Danielle M., Ha, Thoa K., Lindsay, Michael K., and Chandrasekaran, Suchitra

Subjects
DISEASE risk factors, CEREBROVASCULAR disease risk factors, THROMBOEMBOLISM risk factors, RISK assessment, SICKLE cell anemia, DELIVERY (Obstetrics), PATIENTS, ADULT respiratory distress syndrome, MOTHERS, HOSPITAL admission & discharge, PUERPERAL disorders, RETROSPECTIVE studies, DESCRIPTIVE statistics, MATERNAL mortality, PREGNANT women, DISCHARGE planning, ACUTE kidney failure, LONGITUDINAL method, MEDICAL records, ACQUISITION of data, URBAN hospitals, SEPSIS, CONFIDENCE intervals, COMPARATIVE studies, GAS embolism, PERINATAL period, NOSOLOGY, DISEASE complications, PREGNANCY
Abstract

Objective To compare the risk of severe maternal morbidity (SMM) from the delivery admission to 42 days' postdischarge among persons with sickle cell disease (SCD) to those without SCD. Study Design This retrospective cohort study included deliveries ≥20 weeks' gestation at an urban safety net hospital in Atlanta, GA from 2011 to 2019. The exposure was SCD diagnosis. The outcome was a composite of SMM from the delivery admission to 42 days' postdischarge. SMM indicators as defined by the Centers for Disease Control and Prevention were identified using the International Classification of Diseases, Ninth and Tenth Revisions (ICD-9/10) codes; transfusion of blood products and sickle cell crisis were excluded. Results Of N = 17,354 delivery admissions, n = 92 (0.53%) had SCD. Persons with SCD versus without SCD had an increased risk of composite SMM (15.22 vs. 2.29%, p < 0.001), acute renal failure (6.52 vs. 0.71%, p < 0.001), acute respiratory distress syndrome (4.35 vs. 0.17%, p < 0.001), puerperal cerebrovascular disorders (3.26 vs. 0.10%, p < 0.001), sepsis (4.35 vs. 0.42%, p < 0.01), air and thrombotic embolism (5.43 vs. 0.10%, p < 0.001), and ventilation (2.17 vs. 0.09%, p < 0.01). Ultimately, those with SCD had an approximately 6-fold higher incidence risk ratio of SMM, which remained after adjustment for confounders (adjusted incidence risk ratio [aIRR]: 5.96, 95% confidence interval [CI]: 3.4–9.19, p < 0.001). Persons with SCD in active vaso-occlusive crisis at the delivery admission had an approximately 9-fold higher risk of SMM up to 42 days' postdischarge compared with those with SCD not in crisis at the delivery admission (incidence: 25.71 vs. 8.77%, p < 0.05; aIRR: 8.92, 95% CI: 4.5–10.04, p < 0.05). Among those with SCD, SMM at the delivery admission was primarily related to renal and cerebrovascular events, whereas most postpartum SMM was related to respiratory events or sepsis. Conclusion SCD is significantly associated with an increased risk of SMM during the delivery admission and through 42 days' postdischarge. Active crisis at delivery further increases the risk of SMM. Key Points Sickle cell disease was associated with an approximately 6-fold increased risk of SMM. Active vaso-occlusive crisis at delivery was associated with an approximately 9-fold increased risk of SMM. 48% of SMM events in persons with SCD occurred postpartum and were respiratory- or sepsis-related. [ABSTRACT FROM AUTHOR]

Published
2024
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12. Enabling the Warfighter 9th CBRNE Company Supports 1-2 SBCT CALFEX

Author

Lindsay, Michael T. and Williams, Tecarlos Y.

Subjects
United States. Army, Soldiers, Weapons of mass destruction, Chemicals, plastics and rubber industries, Military and naval science
Abstract

Our foundational task and purpose as a Chemical Corps is to enable the warfighter in its chemical, biological, radiological, nuclear, and explosives (CBRNE)/countering weapons of mass destruction (CWMD) mission. As [...]

Published
2018

31. Murray Valley encephalitis virus surveillance and control initiatives in Australia

Author

Spencer, Jenean D., Azoulas, Joe, Broom, Annette K., Buick, Tim D., Daniels, Peter W., Doggett, Stephen L., Hapgood, George D., Jarrett, Peter J., Lindsay, Michael D., Lloyd, Glenis, Mackenzie, John S., Merianos, Angela, Moran, Rodney J., Ritchie, Scott A., Russell, Richard C., Smith, David W., Stenhouse, Fay O., and Whelan, Peter I.

Published
2001

41. "On China's Descending Spiral"

Author

Eckstein, Alexander, Hudson, G. F., La Dany, L., Li, Choh-Ming, Lindsay, Michael, MacLeish, Roderick, Robertson, Frank, Walker, Kenneth R., Walker, Richard L., and Wu, Yuan-Li

Published
1962

43. The Puzzle of M&A.

Author

LINDSAY, MICHAEL A.

Subjects
*GENERATIVE artificial intelligence, *MERGERS & acquisitions, *MERGERS & acquisitions law, *COFFEE shops, *POPULAR culture, *ANTITRUST law
Abstract

This article, titled "The Puzzle of M&A," discusses the complexities and challenges of mergers and acquisitions (M&A) transactions. It highlights the importance of selecting compatible companies or assets for successful M&A deals, as forcing ill-matched entities together can lead to failure. The article also explores the role of antitrust law in M&A transactions, with a focus on the 2023 Merger Guidelines issued by the U.S. Department of Justice and the Federal Trade Commission. Different perspectives on the guidelines are presented, including discussions on harm to the competitive process, the efficiencies defense, and the role of consumer welfare in antitrust. The article also touches on other topics such as the notification process at the United Kingdom's Competition & Markets Authority, generative AI, pricing algorithms, the European Union's Foreign Subsidies Regulation, and antitrust in pop culture. Overall, the article aims to provide insights and guidance to practitioners navigating the complex landscape of antitrust law in the context of M&A transactions. [Extracted from the article]

Published
2024

47. Comm for Small Sats: The Lunar Atmosphere and Dust Environment Explorer (LADEE) Communications Subsystem

Author

Kuroda, Vanessa M, Allard, Mark R, Lewis, Brian, and Lindsay, Michael

Subjects
Space Communications, Spacecraft Communications, Command And Tracking, Ground Support Systems And Facilities (Space)
Abstract

September 6, 2013 through April 21, 2014 marked the mission lifecycle of the highly successful LADEE (Lunar Atmosphere and Dust Environment Explorer) mission that orbited the moon to gather detailed information about the thin lunar atmosphere. This paper will address the development, risks, and lessons learned regarding the specification, selection, and deployment of LADEE's unique Radio Frequency based communications subsystem and supporting tools. This includes the Electronic Ground Support Equipment (EGSE), test regimes, and RF dynamic link analysis environment developed to meet mission requirements for small, flexible, low cost, high performance, fast turnaround, and reusable spacecraft communication capabilities with easy and reliable application to future similar low cost small satellite missions over widely varying needs for communications and communications system complexity. LADEE communication subsystem key components, architecture, and mission performance will be reviewed toward applicability for future mission planning, design, and utilization.

Published
2014

48. Rapid human immunodeficiency virus testing in labor and delivery: a comparison of implementation models between 2 hospitals

Author

Dennis, Renata L., Negron, Terri J., Lindsay, Michael, Nesheim, Steven R., Lee, Francis K., and Jamieson, Denise J.

Subjects
HIV testing -- Standards, HIV testing -- Comparative analysis, Medical screening -- Models, Medical screening -- Comparative analysis, Hospital maternity services -- Models, Hospital maternity services -- Comparative analysis, High risk pregnancy -- Care and treatment, HIV infection in children -- Prevention, Health, Health care industry
Published
2007

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