1,382 results on '"Lindquist, Susan"'
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2. Inhibiting mitochondrial phosphate transport as an unexploited antifungal strategy
3. Deep sequencing of proteotoxicity modifier genes uncovers a Presenilin-2/beta-amyloid-actin genetic risk module shared among alpha-synucleinopathies
4. Inhibition of translation initiation factor eIF4a inactivates heat shock factor 1 (HSF1) and exerts anti-leukemia activity in AML
5. An HSF1-JMJD6-HSP feedback circuit promotes cell adaptation to proteotoxic stress.
6. HSF1 phase transition mediates stress adaptation and cell fate decisions
7. Cross-Kingdom Chemical Communication Drives a Heritable, Mutually Beneficial Prion-Based Transformation of Metabolism
8. The Stress Response and Stress Proteins
9. FKBP12 contributes to α-synuclein toxicity by regulating the calcineurin-dependent phosphoproteome
10. Mitochondrial metabolism promotes adaptation to proteotoxic stress
11. α-Synuclein Blocks ER-Golgi Traffic and Rab1 Rescues Neuron Loss in Parkinson's Models
12. Hsp90 Potentiates the Rapid Evolution of New Traits: Drug Resistance in Diverse Fungi
13. Genetic Interactions between [PSI + ] and Nonstop mRNA Decay Affect Phenotypic Variation
14. Potent Inhibition of Huntingtin Aggregation and Cytotoxicity by a Disulfide Bond-Free Single-Domain Intracellular Antibody
15. Effects of Q/N-Rich, PolyQ, and Non-PolyQ Amyloids on the de novo Formation of the [PSI + ] Prion in Yeast and Aggregation of Sup35 in vitro
16. Hsp104 Catalyzes Formation and Elimination of Self-Replicating Sup35 Prion Conformers
17. Cells Have Distinct Mechanisms to Maintain Protection against Different Reactive Oxygen Species: Oxidative-Stress-Response Genes
18. The Elongation of Yeast Prion Fibers Involves Separable Steps of Association and Conversion
19. Combining DNP NMR with segmental and specific labeling to study a yeast prion protein strain that is not parallel in-register
20. Suppression of 19S proteasome subunits marks emergence of an altered cell state in diverse cancers
21. Yeast Cells Provide Insight into Alpha-Synuclein Biology and Pathobiology
22. Yeast Genes That Enhance the Toxicity of a Mutant Huntingtin Fragment or α-Synuclein
23. Conducting Nanowires Built by Controlled Self-Assembly of Amyloid Fibers and Selective Metal Deposition
24. Changes in the Middle Region of Sup35 Profoundly Alter the Nature of Epigenetic Inheritance for the Yeast Prion [PSI +]
25. Neurotoxicity and Neurodegeneration When PrP Accumulates in the Cytosol
26. Conversion of PrP to a Self-Perpetuating $PrP^{Sc}-like$ Conformation in the Cytosol
27. Analysis of the AAA Sensor-2 Motif in the C-Terminal ATPase Domain of Hsp104 with a Site-Specific Fluorescent Probe of Nucleotide Binding
28. Wild-Type PrP and a Mutant Associated with Prion Disease are Subject to Retrograde Transport and Proteasome Degradation
29. Investigating Protein Conformation-Based Inheritance and Disease in Yeast
30. Subunit Interactions Influence the Biochemical and Biological Properties of Hsp104
31. Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus
32. Green tea (−)-epigallocatechin-gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntington's disease models
33. Green tea (-)-epigallocatechin-gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntington's disease models.
34. Nucleated Conformational Conversion and the Replication of Conformational Information by a Prion Determinant
35. Polyglutamine Aggregates Alter Protein Folding Homeostasis in Caenorhabditis elegans
36. Heat Shock Protein 101 Plays a Crucial Role in Thermotolerance in Arabidopsis
37. Aggregation of Huntingtin in Yeast Varies with the Length of the Polyglutamine Expansion and the Expression of Chaperone Proteins
38. Creating a Protein-Based Element of Inheritance
39. Identification of SSF1, CNS1, and HCH1 as Multicopy Suppressors of a Saccharomyces cerevisiae Hsp90 Loss-of-Function Mutation
40. Maturation of the Tyrosine Kinase C-Src as a Kinase and as a Substrate Depends on the Molecular Chaperone Hsp90
41. Chaperone-Supervised Conversion of Prion Protein to Its Protease-Resistant Form
42. Interactions of the Chaperone Hsp104 with Yeast Sup35 and Mammalian PrP
43. In vivo Functions of the Saccharomyces cerevisiae Hsp90 Chaperone
44. Supplementary Data from Rebalancing Protein Homeostasis Enhances Tumor Antigen Presentation
45. Supplementary Figures from Rebalancing Protein Homeostasis Enhances Tumor Antigen Presentation
46. Supplementary Figure Legends from Endothelial Thermotolerance Impairs Nanoparticle Transport in Tumors
47. Supplementary Figures S1-S10 from Endothelial Thermotolerance Impairs Nanoparticle Transport in Tumors
48. Data from Endothelial Thermotolerance Impairs Nanoparticle Transport in Tumors
49. Support for the Prion Hypothesis for Inheritance of a Phenotypic Trait in Yeast
50. Heat-Shock Protein 104 Expression is Sufficient for Thermotolerance in Yeast
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