Search

Your search keyword '"Lin, Yifen"' showing total 337 results
Start Over Author "Lin, Yifen"
337 results on '"Lin, Yifen"'

6. Exogenous γ-Aminobutyric Acid Delays Chilling Injury of Harvested Kiwifruit and Relates with Reactive Oxygen Species Metabolism

Author

XIA Minghui, ZHANG Shen, ZHAO Yunfeng, WANG Ying, HE Fan, CHEN Fahe, LIN Yifen, CHEN Fuquan

Subjects
kiwifruit, γ-aminobutyric acid, chilling injury, reactive oxygen species, ascorbate-glutathione cycle, Food processing and manufacture, TP368-456
Abstract

The effect of γ-aminobutyric acid (GABA) treatment on chilling injury in cold-stored kiwifruit and its relationship with reactive oxygen species (ROS) metabolism were investigated. Postharvest kiwifruit were treated with 2.0 mmol/L GABA solution for 20 min and stored at (4 ± 1) ℃ and (85 ± 5)% relative humidity. Chilling injury development was evaluated and the changes in the dynamic balance between the production and removal of ROS were analyzed. The results showed that compared with the control group, GABA treatment could delay the increases in the chilling injury index, cell membrane permeability and malondialdehyde (MDA) content of cold-stored kiwifruit, inhibit the rate of superoxide anion radical production and the increase in hydrogen peroxide content, and increase and maintain superoxide dismutase (SOD), catalase (CAT), ascorbate peroxidase (APX), glutathione reductase (GR), monodehydroascorbate reductase (MDHAR) and dehydroascorbate reductase (DHAR) activities. Moreover, GABA treatment slowed down the decrease in the contents of ascorbic acid and glutathione, which contributed to higher antioxidant capacity levels in the fruit. The above findings indicated that exogenous GABA treatment could maintain dynamic redox balance, attenuate membrane lipid peroxidation and preserve cell membrane integrity in cold-stored kiwifruit by inhibiting the accumulation of ROS, and increasing the activities of the enzymatic and non-enzymatic ROS systems, thereby enhancing cold stress resistance and ultimately delaying chilling injury.

Published
2023
Full Text
View/download PDF

46. Serum Klotho Modifies the Associations of 25-Hydroxy Vitamin D With All-Cause and Cardiovascular Mortality.

Author

Chen, Zhuohui, Liu, Menghui, Xu, Xingfeng, He, Lixiang, Wang, Peng, Cai, Xiaojie, Huang, Rihua, Zhang, Shaozhao, Xu, Xinghao, Lai, Yuhui, Huang, Yiquan, Li, Miaohong, Lin, Yifen, Xie, Peihan, Liao, Xinxue, Zhuang, Xiaodong, and Guo, Yue

Subjects
CARDIOVASCULAR disease related mortality, VITAMIN D metabolism, BLOOD serum analysis
Abstract

Background The association between 25-hydroxyvitamin D and mortality remains controversial. Klotho, a biomarker of vitamin D activation and metabolism, may play a key role in this association. However, it is unclear whether the association between vitamin D deficiency and mortality risk is modified by klotho levels. Therefore, this study investigated the joint association of serum 25-hydroxyvitamin D [25(OH)D] and klotho with mortality risk in American community-dwelling adults. Methods A total of 9870 adults from the National Health and Nutrition Examination Survey (2007-2016) were included in our study. Mortality data were ascertained by linking participants to National Death Index records. Cox proportional hazards models were used to assess the association among serum 25(OH)D, serum klotho, and all-cause and cardiovascular disease (CVD) mortality. Results We found a significant interaction between klotho and serum 25(OH)D in all-cause mortality (P =.028). With klotho > 848.4 pg/mL (risk threshold on mortality), no significant all-cause and CVD mortality risk was observed at any level of serum 25(OH)D. However, with klotho < 848.4 pg/mL, a significant all-cause and CVD mortality risk was observed with serum 25(OH)D < 50 nmol/L [hazards ratio (HR), 1.36; 95% confidence interval (CI), 1.10-1.69; HR, 1.78; 95% CI, 1.16-3.45) and serum 25(OH)D of continuous variable (HR, 0.98; 95% CI,.97-.99; HR, 0.98; 95% CI,.98-.99). In addition, vitamin D metabolism disruption accessed by the combination of decreasing serum 25(OH)D (<50 nmol/L) and klotho (<848.4 pg/mL) was associated with significant all-cause mortality (HR, 1.48; 95% CI, 1.11-1.96) and CVD mortality (HR, 2.36; 95% CI, 1.48-3.75). Conclusions Vitamin D-associated mortality risk is observed only with concurrently decreasing klotho, indicating that vitamin D metabolism dysfunction increases the risk of mortality. Klotho levels could help predict long-term mortality outcomes and thus may be useful concurrently for guiding vitamin D supplementation therapy decision-making in populations with vitamin D deficiency. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

49. Serum klotho modifies the associations of 25-hydroxy vitamin D with all-cause and cardiovascular mortality

Author

Chen, Zhuohui, primary, Liu, Menghui, additional, Xu, Xingfeng, additional, He, Lixiang, additional, Wang, Peng, additional, Cai, Xiaojie, additional, Huang, Rihua, additional, Zhang, Shaozhao, additional, Xu, Xinghao, additional, Lai, Yuhui, additional, Huang, Yiquan, additional, Li, Miaohong, additional, Lin, Yifen, additional, Xie, Peihan, additional, Liao, Xinxue, additional, Zhuang, Xiaodong, additional, and Guo, Yue, additional

Published
2023
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results