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2. Skin sympathetic nerve activity and ventricular arrhythmias in acute coronary syndrome

Author

Huang, Tien-Chi, Lin, Shin-Jing, Chen, Chang-Jen, Jhuo, Shih-Jie, Chang, Chien-Wei, Lin, Shih-Ching, Chi, Nai-Yu, Chou, Li-Fang, Tai, Li-Hsin, Liu, Yi-Hsueh, Lin, Tsung-Han, Liao, Wei-Sheng, Kao, Pei-Heng, Cheng, Mu-Chun, Hsu, Po-Chao, Lee, Chee-Siong, Lin, Yi-Hsiung, Lee, Hsiang-Chun, Lu, Ye-Hsu, Yen, Hsueh-Wei, Lin, Tsung-Hsien, Su, Ho-Ming, Lai, Wen-Ter, Dai, Chia-Yen, Lee, Chien-Hung, Chen, Peng-Sheng, Lin, Shien-Fong, and Tsai, Wei-Chung

Published
2022
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9. Autoantibodies neutralizing type I IFNs underlie West Nile virus encephalitis in ∼40% of patients

Author

Gervais, Adrian, primary, Rovida, Francesca, additional, Avanzini, Maria Antonietta, additional, Croce, Stefania, additional, Marchal, Astrid, additional, Lin, Shih-Ching, additional, Ferrari, Alessandro, additional, Thorball, Christian W., additional, Constant, Orianne, additional, Le Voyer, Tom, additional, Philippot, Quentin, additional, Rosain, Jérémie, additional, Angelini, Micol, additional, Pérez Lorenzo, Malena, additional, Bizien, Lucy, additional, Achille, Cristian, additional, Trespidi, Francesca, additional, Burdino, Elisa, additional, Cassaniti, Irene, additional, Lilleri, Daniele, additional, Fornara, Chiara, additional, Sammartino, José Camilla, additional, Cereda, Danilo, additional, Marrocu, Chiara, additional, Piralla, Antonio, additional, Valsecchi, Chiara, additional, Ricagno, Stefano, additional, Cogo, Paola, additional, Neth, Olaf, additional, Marín-Cruz, Inés, additional, Pacenti, Monia, additional, Sinigaglia, Alessandro, additional, Trevisan, Marta, additional, Volpe, Andrea, additional, Marzollo, Antonio, additional, Conti, Francesca, additional, Lazzarotto, Tiziana, additional, Pession, Andrea, additional, Viale, Pierluigi, additional, Fellay, Jacques, additional, Ghirardello, Stefano, additional, Aubart, Mélodie, additional, Ghisetti, Valeria, additional, Aiuti, Alessandro, additional, Jouanguy, Emmanuelle, additional, Bastard, Paul, additional, Percivalle, Elena, additional, Baldanti, Fausto, additional, Puel, Anne, additional, MacDonald, Margaret R., additional, Rice, Charles M., additional, Rossini, Giada, additional, Murray, Kristy O., additional, Simonin, Yannick, additional, Nagy, Anna, additional, Barzon, Luisa, additional, Abel, Laurent, additional, Diamond, Michael S., additional, Cobat, Aurélie, additional, Zhang, Shen-Ying, additional, Casanova, Jean-Laurent, additional, and Borghesi, Alessandro, additional

Published
2023
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10. Message Delivery of Cultural and Creative Products Under Cultural Industries

Author

Chen, Chi-Hsiung, Lin, Shih-Ching, Diniz Junqueira Barbosa, Simone, Series editor, Chen, Phoebe, Series editor, Du, Xiaoyong, Series editor, Filipe, Joaquim, Series editor, Kara, Orhun, Series editor, Liu, Ting, Series editor, Kotenko, Igor, Series editor, Sivalingam, Krishna M., Series editor, Washio, Takashi, Series editor, and Stephanidis, Constantine, editor

Published
2016
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12. The Study of Style for Kogi Pottery Art in Life

Author

Chen, Chi-Hsiung, Lin, Shih-Ching, Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Pandu Rangan, C., editor, Steffen, Bernhard, editor, Sudan, Madhu, editor, Terzopoulos, Demetri, editor, Tygar, Doug, editor, Vardi, Moshe Y., editor, Weikum, Gerhard, editor, and Rau, P. L. Patrick, editor

Published
2013
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13. Variants in Interferon Lambda are Associated with Very Early Onset Inflammatory Bowel Disease

Author

Ouahed, Jodie D., primary, Broggi, Achille, additional, Glick, Abigail, additional, Haring, Robin T., additional, Field, Michael, additional, Chinnapen, Daniel, additional, Grey, Michael J., additional, Lencer, Wayne, additional, Steiner, Steven J., additional, Dennis-Heyward, Evida, additional, Shroyer, Noah, additional, Criss, Zachary, additional, Lin, Shih-Ching, additional, Zeng, Xi-Lei, additional, Crawford, Sue E., additional, Estes, Mary K., additional, Thiagarajah, Jay R., additional, Capilla, Amalia, additional, Scoon, Whitney, additional, Mostoslavsky, Gustavo, additional, Spence, Jason, additional, Klein, Christoph, additional, Muise, Aleixo M., additional, Horwitz, Bruce, additional, Zanoni, Ivan, additional, and Snapper, Scott B., additional

Published
2022
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16. Bile Goes Viral

Author

Tenge, Victoria R., primary, Murakami, Kosuke, additional, Salmen, Wilhelm, additional, Lin, Shih-Ching, additional, Crawford, Sue E., additional, Neill, Frederick H., additional, Prasad, B. V. Venkataram, additional, Atmar, Robert L., additional, and Estes, Mary K., additional

Published
2021
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17. Systematic functional analysis of rab GTPases reveals limits of neuronal robustness to environmental challenges in flies

Author

Kohrs, Friederike E, primary, Daumann, Ilsa-Maria, additional, Pavlovic, Bojana, additional, Jin, Eugene Jennifer, additional, Kiral, F Ridvan, additional, Lin, Shih-Ching, additional, Port, Filip, additional, Wolfenberg, Heike, additional, Mathejczyk, Thomas F, additional, Linneweber, Gerit A, additional, Chan, Chih-Chiang, additional, Boutros, Michael, additional, and Hiesinger, P Robin, additional

Published
2021
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18. Histo-blood group antigens of glycosphingolipids predict susceptibility of human intestinal enteroids to norovirus infection

Author

Rimkute, Inga, Thorsteinsson, Konrad, Henricsson, Marcus, Tenge, Victoria R., Yu, Xiaoming, Lin, Shih-Ching, Haga, Kei, Atmar, Robert L., Lycke, Nils, Nilsson, Jonas, Estes, Mary K., Bally, Marta, Larson, Göran, Rimkute, Inga, Thorsteinsson, Konrad, Henricsson, Marcus, Tenge, Victoria R., Yu, Xiaoming, Lin, Shih-Ching, Haga, Kei, Atmar, Robert L., Lycke, Nils, Nilsson, Jonas, Estes, Mary K., Bally, Marta, and Larson, Göran

Abstract

The molecular mechanisms behind infection and propagation of human restricted pathogens such as human norovirus (HuNoV) have defied interrogation because they were previously unculturable. However, human intestinal enteroids (HIEs) have emerged to offer unique ex vivo models for targeted studies of intestinal biology, including inflammatory and infectious diseases. Carbohydrate-dependent histo-blood group antigens (HBGAs) are known to be critical for clinical infection. To explore whether HBGAs of glycosphingolipids contribute to HuNoV infection, we obtained HIE cultures established from stem cells isolated from jejunal biopsies of six individuals with different ABO, Lewis, and secretor genotypes. We analyzed their glycerolipid and sphingolipid compositions and quantified interaction kinetics and the affinity of HuNoV virus-like particles (VLPs) to lipid vesicles produced from the individual HIE-lipid extracts. All HIEs had a similar lipid and glycerolipid composition. Sphingolipids included HBGA-related type 1 chain glycosphingolipids (GSLs), with HBGA epitopes corresponding to the geno- and phenotypes of the different HIEs. As revealed by single-particle interaction studies of Sydney GII.4 VLPs with glycosphingolipid-containing HIE membranes, both binding kinetics and affinities explain the patterns of susceptibility toward GII.4 infection for individual HIEs. This is the first time norovirus VLPs have been shown to interact specifically with secretor gene-dependent GSLs embedded in lipid membranes of HIEs that propagate GII.4 HuNoV ex vivo, highlighting the potential of HIEs for advanced future studies of intestinal glycobiology and host-pathogen interactions.

Published
2020
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19. Author response: Systematic functional analysis of rab GTPases reveals limits of neuronal robustness to environmental challenges in flies

Author

Kohrs, Friederike E, primary, Daumann, Ilsa-Maria, additional, Pavlovic, Bojana, additional, Jin, Eugene Jennifer, additional, Kiral, F Ridvan, additional, Lin, Shih-Ching, additional, Port, Filip, additional, Wolfenberg, Heike, additional, Mathejczyk, Thomas F, additional, Linneweber, Gerit A, additional, Chan, Chih-Chiang, additional, Boutros, Michael, additional, and Hiesinger, P Robin, additional

Published
2021
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20. Histo-blood group antigens of glycosphingolipids predict susceptibility of human intestinal enteroids to norovirus infection

Author

Rimkute, Inga, primary, Thorsteinsson, Konrad, additional, Henricsson, Marcus, additional, Tenge, Victoria R., additional, Yu, Xiaoming, additional, Lin, Shih-Ching, additional, Haga, Kei, additional, Atmar, Robert L., additional, Lycke, Nils, additional, Nilsson, Jonas, additional, Estes, Mary K., additional, Bally, Marta, additional, and Larson, Göran, additional

Published
2020
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22. 588 GII.3 HUMAN NOROVIRUS REQUIRES BILE ACID AND CERAMIDE FOR ENTRY AND INFECTION OF HUMAN INTESTINAL ENTEROIDS

Author

Tenge, Victoria R., primary, Murakami, Kosuke, additional, Karandikar, Umesh C., additional, Lin, Shih-Ching, additional, Ramani, Sasirekha, additional, Ettayebi, Khalil, additional, Crawford, Sue E., additional, Zeng, Xi-Lei, additional, Neill, Frederick H., additional, Ayyar, B. Vijayalakshmi, additional, Katayama, Kazuhiko, additional, Graham, David Y., additional, Bieberich, Erhard, additional, Atmar, Robert L., additional, and Estes, Mary, additional

Published
2020
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23. Genetic Manipulation of Human Intestinal Enteroids Demonstrates the Necessity of a Functional Fucosyltransferase 2 Gene for Secretor-Dependent Human Norovirus Infection

Author

Haga, Kei, primary, Ettayebi, Khalil, additional, Tenge, Victoria R., additional, Karandikar, Umesh C., additional, Lewis, Miranda A., additional, Lin, Shih-Ching, additional, Neill, Frederick H., additional, Ayyar, B. Vijayalakshmi, additional, Zeng, Xi-Lei, additional, Larson, Göran, additional, Ramani, Sasirekha, additional, Atmar, Robert L., additional, and Estes, Mary K., additional

Published
2020
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24. Systematic functional analysis of Rab GTPases reveals limits of neuronal robustness in Drosophila

Author

Kohrs, Friederike E., primary, Daumann, Ilsa-Maria, additional, Pavlović, Bojana, additional, Jin, Eugene Jennifer, additional, Lin, Shih-Ching, additional, Port, Fillip, additional, Kiral, F. Ridvan, additional, Wolfenberg, Heike, additional, Mathejczyk, Thomas F., additional, Chan, Chih-Chiang, additional, Boutros, Michael, additional, and Hiesinger, P. Robin, additional

Published
2020
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25. Human Norovirus Cultivation in Nontransformed Stem Cell-Derived Human Intestinal Enteroid Cultures: Success and Challenges

Author

Estes, Mary K., primary, Ettayebi, Khalil, additional, Tenge, Victoria R., additional, Murakami, Kosuke, additional, Karandikar, Umesh, additional, Lin, Shih-Ching, additional, Ayyar, B. Vijayalakshmi, additional, Cortes-Penfield, Nicolas W., additional, Haga, Kei, additional, Neill, Frederick H., additional, Opekun, Antone R., additional, Broughman, James R., additional, Zeng, Xi-Lei, additional, Blutt, Sarah E., additional, Crawford, Sue E., additional, Ramani, Sasirekha, additional, Graham, David Y., additional, and Atmar, Robert L., additional

Published
2019
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35. Determination of urinary lead, cadmium and nickel in steel production workers

Author

Horng, Ching-Jyi, Tsai, Jin-Lian, Horng, Ping-Hua, Lin, Shih-Ching, Lin, Shinine-Ren, and Tzeng, Cherng-Chyi

Subjects
*URINALYSIS, *METALS in the body
Abstract

The determination of toxic metals in urine is an important clinical screening procedure. In this study, the aim of our investigation was to determine the concentrations of Pb, Cd, and Ni in urine samples under routine clinical laboratory conditions. To assess the reliability of these methods, critical factors such as detection limit(s), calibration range(s), cost, accuracy and precision were studied. The method was employed for the quantitative determination of lead, cadmium and nickel in urine samples from steel production and quality control (QC) workers and healthy unexposed controls. After pre-treatment with acids, the samples were digested via a microwave oven and the samples were determined by a graphite furnace atomic absorption spectrometry (GFAAS). Quality control for these procedures was established with the concurrent analysis of Standard Trace Metals 7879 Level II and NIST SRM 2670 (Toxic Elements in Freeze Dried Urine). The results indicate that urinary lead, cadmium and nickel levels of the exposed workers are significantly higher those of the controls. The possible connection of these elements with the etiology of disease is discussed. The results also show the need for immediate improvements in workplace ventilation and industrial hygiene practices. [Copyright &y& Elsevier]

Published
2002
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