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182 results on '"Lin, Meng-Wei"'

6. Deep Sensing of Urban Waterlogging

Author

Lo, Shi-Wei, Wu, Jyh-Horng, Chang, Jo-Yu, Tseng, Chien-Hao, Lin, Meng-Wei, and Lin, Fang-Pang

Subjects
Computer Science - Computer Vision and Pattern Recognition, Computer Science - Artificial Intelligence, Computer Science - Computers and Society
Abstract

In the monsoon season, sudden flood events occur frequently in urban areas, which hamper the social and economic activities and may threaten the infrastructure and lives. The use of an efficient large-scale waterlogging sensing and information system can provide valuable real-time disaster information to facilitate disaster management and enhance awareness of the general public to alleviate losses during and after flood disasters. Therefore, in this study, a visual sensing approach driven by deep neural networks and information and communication technology was developed to provide an end-to-end mechanism to realize waterlogging sensing and event-location mapping. The use of a deep sensing system in the monsoon season in Taiwan was demonstrated, and waterlogging events were predicted on the island-wide scale. The system could sense approximately 2379 vision sources through an internet of video things framework and transmit the event-location information in 5 min. The proposed approach can sense waterlogging events at a national scale and provide an efficient and highly scalable alternative to conventional waterlogging sensing methods., Comment: 19 pages, 14 figures, under submitting and patenting

Published
2021

9. Prevalence of environmental microplastics in Taiwan and its impact on the seafood safety: An integrative review.

Author

Lin, Meng‐Wei, Wu, Vivian C. H., and Lin, Chih‐Sheng

Subjects
*ENVIRONMENTAL health, *MICROPLASTICS, *DIETARY proteins, *SEAFOOD, *SEAFOOD industry, *FOOD safety, *BIODEGRADABLE plastics, *WILD animal trade
Abstract

Human activity has led to microplastic contamination throughout the marine environment. As a result of widespread contamination, microplastics are ingested by many species of wildlife, including fish, cephalopods, and shellfish. Taiwan is surrounded by oceans that offer a rich range of seafood. Taiwanese residents can easily acquire seafood as a source of dietary protein. A recent research project by Greenpeace shows that the Taiwanese eat 16,000 microplastic particles per year. There is concern regarding microplastic physical and chemical toxicity, which poses potential health risks to the local community via food chains. Thus, monitoring microplastic contamination in seafood is imperative to provide helpful information for the government and local communities. Efforts should be taken to reduce microplastic pollution at the source to minimize potential effects on ecological and health safety. This review article emphasizes the urgent need for further research on microplastic pollution in Taiwan, highlights the potential challenges to mitigate this emerging environmental threat, and analyzes food safety hazards as well as microplastic contamination in seafood. [ABSTRACT FROM AUTHOR]

Published
2024
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10. Constructing the Polymer Molecules to Regulate the Electrode/Electrolyte Interface to Enhance Lithium‐Metal Battery Performance.

Author

Chen, Hui, Xie, Yu‐Xiang, Dong, Long‐Ji, Peng, Hao, Lin, Meng‐Wei, Sun, Miao‐Lan, Liu, Shi‐Shi, Ma, Jun‐Bo, Huang, Ling, and Sun, Shi‐Gang

Subjects
METHYL methacrylate, ELECTROLYTES, ENERGY density, SOLID electrolytes, ETHYLENE glycol, POLYELECTROLYTES, POLYMERS
Abstract

Lithium‐ion batteries, with high energy density and long cycle life, have become the battery of choice for most vehicles and portable electronic devices; however, energy density, safety and cycle life require further improvements. Single‐functional group electrolyte additives are very limited in practical applications, a ternary polymer bifunctional electrolyte additive copolymer (acrylonitrile‐butyl hexafluoro methacrylate‐ poly (ethylene glycol) methacrylate‐ methyl ether) (PMANHF) was synthesized by free radical polymerization of acrylonitrile, 2, 2, 3, 4, 4, 4‐hexafluorobutyl methacrylate and poly (ethylene glycol) methyl ether methacrylate. A series of characterizations show that in Li metal anodes, the preferential reduction of PMANHF is conducive to the formation of a uniform and stable solid electrolyte interphase layer, and Li deposition is uniform and dense. At the NCM811 cathode, a film composed of LiF‐ and Li3N‐rich is formed at the cathode‐electrolyte interface, mitigating the side reaction at the interface. At 1.0 mA cm−2, the Li/Li cell can be stabilized for 1000 cycles. In addition, the Li/NCM811 cell can stabilize 200 cycles with a cathode capacity of 153.7 mAh g−1, with the capacity retention of 89.93 %, at a negative/positive capacity ratio of 2.5. This study brings to light essential ideas for the fabrication of additives for lithium‐metal batteries. [ABSTRACT FROM AUTHOR]

Published
2024
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20. Studying the Roles of the Renin–Angiotensin System in Accelerating the Disease of High-Fat-Diet-Induced Diabetic Nephropathy in a db/db and ACE2 Double-Gene-Knockout Mouse Model.

Author

Chen, Cheng-Yi, Lin, Meng-Wei, Xie, Xing-Yang, Lin, Cheng-Han, Yang, Chung-Wei, Wu, Pei-Ching, Liu, Dung-Huan, Wu, Chih-Jen, and Lin, Chih-Sheng

Subjects
*DIABETIC nephropathies, *RENIN-angiotensin system, *ANGIOTENSIN converting enzyme, *LABORATORY mice, *ANGIOTENSIN I, *ANIMAL disease models
Abstract

Diabetic nephropathy (DN) is a crucial metabolic health problem. The renin–angiotensin system (RAS) is well known to play an important role in DN. Abnormal RAS activity can cause the over-accumulation of angiotensin II (Ang II). Angiotensin-converting enzyme inhibitor (ACEI) administration has been proposed as a therapy, but previous studies have also indicated that chymase, the enzyme that hydrolyzes angiotensin I to Ang II in an ACE-independent pathway, may play an important role in the progression of DN. Therefore, this study established a model of severe DN progression in a db/db and ACE2 KO mouse model (db and ACE2 double-gene-knockout mice) to explore the roles of RAS factors in DNA and changes in their activity after short-term (only 4 weeks) feeding of a high-fat diet (HFD) to 8-week-old mice. The results indicate that FD-fed db/db and ACE2 KO mice fed an HFD represent a good model for investigating the role of RAS in DN. An HFD promotes the activation of MAPK, including p-JNK and p-p38, as well as the RAS signaling pathway, leading to renal damage in mice. Blocking Ang II/AT1R could alleviate the progression of DN after administration of ACEI or chymase inhibitor (CI). Both ACE and chymase are highly involved in Ang II generation in HFD-induced DN; therefore, ACEI and CI are potential treatments for DN. [ABSTRACT FROM AUTHOR]

Published
2024
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28. Proteomic and microbial assessments on the effect of Antrodia cinnamomea in C57BL/6 mice

Author

Tsai, Yi-Ting, primary, Ruan, Jhen-Wei, additional, Chang, Cherng-Shyang, additional, Ko, Mei-Lan, additional, Chou, Hsiu-Chuan, additional, Lin, Chi-Chien, additional, Lin, Chiao-Mei, additional, Huang, Chih-Ting, additional, Wei, Yu-Shan, additional, Liao, En-Chi, additional, Chen, Hsin-Yi, additional, Lin, Li-Hsun, additional, Lin, Meng-Wei, additional, Kao, Cheng-Yuan, additional, and Chan, Hong-Lin, additional

Published
2021
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29. Characterization of TGF-β by Induced Oxidative Stress in Human Trabecular Meshwork Cells

Author

Chen, Hsin-Yi, primary, Chou, Hsiu-Chuan, additional, Ho, Yi-Jung, additional, Chang, Shing-Jyh, additional, Liao, En-Chi, additional, Wei, Yu-Shan, additional, Lin, Meng-Wei, additional, Wang, Yi-Shiuan, additional, Chien, Yu-An, additional, Yu, Xin-Ru, additional, Kung, Hsiang-Yu, additional, Yang, Chu-Chun, additional, Chen, Jia-Yu, additional, Chan, Hong-Lin, additional, and Ko, Mei-Lan, additional

Published
2021
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31. Biomarker discovery in highly invasive lung cancer cell through proteomics approaches

Author

Kuo, Chin‐Ho, primary, Lin, Meng‐Wei, additional, Hsu, Yu‐Wei, additional, Chou, Hsiu‐Chuan, additional, Lin, Li‐Hsun, additional, Law, Ching‐Hsuan, additional, Lin, Yi‐Chieh, additional, Hu, Ren‐Yu, additional, Kuo, Wen‐Hung, additional, Ko, Mei‐Lan, additional, Chang, Shing‐Jyh, additional, Lee, Ying‐Ray, additional, and Chan, Hong‐Lin, additional

Published
2020
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36. Progesterone receptor membrane component 1 is involved in oral cancer cell metastasis

Author

Huang, Hsun‐Yu, primary, Chou, Hsiu‐Chuan, additional, Law, Ching‐Hsuan, additional, Chang, Wan‐Ting, additional, Wen, Tzu‐Ning, additional, Liao, En‐Chi, additional, Lin, Meng‐Wei, additional, Lin, Li‐Hsun, additional, Wei, Yu‐Shan, additional, Tsai, Yi‐Ting, additional, Chen, Hsin‐Yi, additional, Tan, Kui‐Thong, additional, Kuo, Wen‐Hung, additional, Ko, Mei‐Lan, additional, Chang, Shing‐Jyh, additional, Lee, Ying‐Ray, additional, and Chan, Hong‐Lin, additional

Published
2020
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42. Biomarker discovery in highly invasive lung cancer cell through proteomics approaches.

Author

Kuo, Chin‐Ho, Lin, Meng‐Wei, Hsu, Yu‐Wei, Chou, Hsiu‐Chuan, Lin, Li‐Hsun, Law, Ching‐Hsuan, Lin, Yi‐Chieh, Hu, Ren‐Yu, Kuo, Wen‐Hung, Ko, Mei‐Lan, Chang, Shing‐Jyh, Lee, Ying‐Ray, and Chan, Hong‐Lin

Subjects
*CANCER invasiveness, *LUNG cancer, *NON-small-cell lung carcinoma, *CANCER cells, *PROTEOMICS
Abstract

Lung cancer is one of the leading causes of cancer‐related death worldwide. The most common type of lung cancer is non‐small cell lung cancer (NSCLC). When NSCLC is detected, patients are typically already in a metastatic stage. Metastasized cancer is a major obstacle of effective treatment and understanding the mechanisms underlying metastasis is critical to treat cancer. Herein, we selected an invasive subpopulation from the human lung cancer cell line A549 using the transwell system and named it as A549‐I5. Invasive and migratory activities of this cell line were analysed using wound healing, invasion, and migration assays. In addition, epithelial‐mesenchymal transition (EMT) markers, such as Snail 1, Twist, Vimentin, N‐cadherin and E‐cadherin, were assessed through immunoblotting. In comparison to A549 cells, the invasive A549‐I5 lung cancer cells had enhanced invasiveness, motility and EMT marker expression. Proteomic analysis identified 83 significantly differentially expressed proteins in A549‐I5 cells. These identified proteins were classified according to their cellular functions and most were involved in cytoskeleton, redox regulation, protein degradation and protein folding. In summary, our results provide potential diagnostic markers and therapeutic candidates for the treatment of NSCLC metastasis. Significance of the study: When NSCLC is detected, most patients are already in a metastatic stage. Herein, we selected an invasive subpopulation from a human lung cancer cell line which had increased EMT markers as well as high wound healing, invasion and migration abilities. Proteomic analysis identified numerous proteins associated with functions in cytoskeleton, redox regulation, protein degradation and protein folding that were differentially expressed in these cells. These results may provide potential diagnostic markers and therapeutic candidates for the treatment of NSCLC metastasis. [ABSTRACT FROM AUTHOR]

Published
2021
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44. Proteomic Analysis of Various Rat Ocular Tissues after Ischemia–Reperfusion Injury and Possible Relevance to Acute Glaucoma

Author

Chen, Hsin-Yi, primary, Chou, Hsiu-Chuan, additional, Chang, Shing-Jyh, additional, Liao, En-Chi, additional, Tsai, Yi-Ting, additional, Wei, Yu-Shan, additional, Li, Ji-Min, additional, Lin, Li-Hsun, additional, Lin, Meng-Wei, additional, Chen, Ying-Jen, additional, Chen, Yu-Sheng, additional, Lin, Chih-Chun, additional, Wang, Yi-Shiuan, additional, Ko, Mei-Lan, additional, and Chan, Hong-Lin, additional

Published
2017
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