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17. Pilot Study on Next-Generation Sequencing Analysis of Vaginal Microbiota in Clinically Infertile Patients Treated with Probiotics.

Author

Lin, Li-Te, Li, Chia-Jung, Wu, Chia-Chun, Pan, Li-Fei, and Tsui, Kuan-Hao

Subjects
*NUCLEOTIDE sequencing, *PROBIOTICS, *HUMAN microbiota, *SEQUENCE analysis, *DIETARY supplements, *FECAL microbiota transplantation
Abstract

Background: In this investigation, we aimed to understand the influence of oral probiotic supplementation on the vaginal microbiota of women preparing for assisted reproductive technology (ART) procedures. Given the importance of a healthy microbiome for reproductive success, this study sought to explore how probiotics might alter the bacterial composition in the vaginal environment. Methods: We recruited a cohort of 30 women, averaging 37 years of age (ranging from 31 to 43 years), who were scheduled to undergo ART. Using 16S ribosomal RNA (rRNA) sequencing, we meticulously analyzed the vaginal microbiota composition before and after the administration of oral probiotic supplements. Results: Our analysis identified 17 distinct microorganisms, including 8 species of Lactobacillus. Following probiotic supplementation, we observed subtle yet notable changes in the vaginal microbiota of some participants. Specifically, there was a decrease in Gardnerella abundance by approximately 20%, and increases in Lactobacillus and Bifidobacterium by 10% and 15%, respectively. Additionally, we noted a significant reduction in the Firmicutes/Bacteroidetes (F/B) ratio in the probiotic group, indicating potential shifts in the overall bacterial composition. Conclusions: These preliminary findings suggest that oral probiotic supplementation can induce significant changes in the vaginal microbiota of middle-aged women undergoing ART, potentially improving their overall bacterial profile. Future studies should consider a larger sample size and a narrower age range to validate these results. Investigating factors related to female hormone production could also provide deeper insights. Understanding the effects of probiotics on the vaginal microbiota in patients with ovarian aging may lead to personalized interventions and better reproductive outcomes. [ABSTRACT FROM AUTHOR]

Published
2024
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23. Women with endometriosis have higher comorbidities: Analysis of domestic data in Taiwan

Author

Chang, Yen-Hou, Chang, Yi, Chao, Kuan-Chong, Chen, Yi-Jen, Chuang, Chi-Mu, Huang, Chen-Yu, Jiang, Ling-Yu, Li, Hsin-Yang, Liu, Chia-Hao, Sun, Pi-Lin, Wen, Kuo-Chang, Wu, Hua-Hsi, Yu, Hann-Chin, Ju, Fong-Yuan, Tsai, Chih-Ping, Chang, Wen-Hsun, Hsu, Yen-Mei, Huang, Shu-Yun, Lee, Na-Rong, Chen, Chih-Yao, Chang, Ting-Chen, Chang, Wen-Chun, Chen, Chii-Hou, Chen, Ruey-Jian, Chow, Song-Nan, Lien, Yih-Ron, Sheu, Bor-Ching, Torng, Pao-Ling, Yen, Men-Luh, Lee, Wen-Ling, Wang, Kuan-Chin, Chang, Chih-Long, Chen, Chih-Ping, Chen, Jen-Ruei, Chen, Tze-Chien, Huang, Jian-Pei, Huang, Ming-Chao, Wang, Yeou-Lih, Chang, Cheng-Chang, Liu, Jah-Yao, Su, Her-Young, Wang, Yu-Chi, Yu, Mu-Hsien, Chu, Ching-Chuang, Huang, Lee-Wen, Seow, Kok-Min, Lai, Tsung-Hsuan, Lee, Fa-Kung, Chen, Ching-Hui, Liu, Wei-Min, Chiou, Jyh-Shin, Huang, Ben-Shian, Lu, Yen-Feng, Hsiao, Sheng-Mou, Sun, Hsu-Dong, Wu, Wen-Yih, Chen, Kuo-Hu, Hung, Jeng-Hsiu, Lai, Hung-Cheng, Yuan, Chiou-Chung, Hsieh, Ching-Hung, Wang, Chin-Jung, Chan, Chia-Hao, Chang, Shing-Jyh, Shih, Chuan-Chi, Hung, Man-Jung, Hsu, Shih-Tien, Ke, Yu-Min, Lu, Chien-Hsing, Sun, Lou, Chang, Wei-Chun, Hung, Yao-Ching, Lin, Wu-Chou, Wang, Po-Hui, Chen, Tze-Ho, Li, Yiu-Tai, Wu, Meng-Hsing, Huang, Kuo-Feng, Chuang, Fei-Chi, Fu, Hung-Chun, Kung, Fu-Tsai, Huang, Kuan-Hui, Chen, San-Nung, Chiang, An-Jen, Li, Ju-Yueh, Lin, Li-Te, Tsai, Hsiao-Wen, Tsui, Kuan-Hao, Teng, Sen-Wen, Horng, Huann-Cheng, Ho, Chi-Hong, Yen, Ming-Shyen, Chao, Hsiang-Tai, and Wang, Peng-Hui

Published
2016
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24. Uterine sarcoma part III—Targeted therapy: The Taiwan Association of Gynecology (TAG) systematic review

Author

Chang, Yen-Hou, Chang, Yi, Chao, Hsiang-Tai, Chao, Kuan-Chong, Chuang, Chi-Mu, Ho, Chi-Hong, Horng, Huann-Cheng, Huang, Chen-Yu, Jiang, Ling-Yu, Liu, Chia-Hao, Li, Hsin-Yang, Sun, Pi-Lin, Wu, Hua-Hsi, Ju, Fong-Yuan, Tsai, Chih-Ping, Chang, Wen-Hsun, Hsu, Yen-Mei, Huang, Shu-Yun, Lee, Na-Rong, Chen, Chih-Yao, Chang, Wen-Chun, Chen, Chii-Hou, Chen, Ruey-Jian, Chow, Song-Nan, Lien, Yih-Ron, Sheu, Bor-Ching, Torng, Pao-Ling, Wei, Lin-Hung, Yen, Men-Luh, Lee, Wen-Ling, Wang, Kuan-Chin, Chang, Chih-Long, Chen, Chih-Ping, Chen, Tze-Chien, Huang, Jian-Pei, Huang, Ming-Chao, Wang, Yeou-Lih, Chang, Cheng-Chang, Liu, Jah-Yao, Su, Her-Young, Wang, Yu-Chi, Yu, Mu-Hsien, Chu, Ching-Chuang, Huang, Lee-Wen, Seow, Kok-Min, Lai, Tsung-Hsuan, Lee, Fa-Kung, Chen, Ching-Hui, Liu, Wei-Min, Chiou, Jyh-Shin, Huang, Ben-Shian, Lu, Yen-Feng, Hsiao, Sheng-Mou, Sun, Hsu-Dong, Wu, Wen-Yih, Teng, Sen-Wen, Chen, Kuo-Hu, Hung, Jeng-Hsiu, Lai, Hung-Cheng, Yuan, Chiou-Chung, Hsieh, Ching-Hung, Wang, Chin-Jung, Chan, Chia-Hao, Chang, Shing-Jyh, Shih, Chuan-Chi, Hung, Man-Jung, Hsu, Shih-Tien, Ke, Yu-Min, Lu, Chien-Hsing, Sun, Lou, Chang, Wei-Chun, Hung, Yao-Ching, Lin, Wu-Chou, Wang, Po-Hui, Chen, Tze-Ho, Wu, Meng-Hsing, Li, Yiu-Tai, Huang, Kuo-Feng, Chuang, Fei-Chi, Fu, Hung-Chun, Kung, Fu-Tsai, Huang, Kuan-Hui, Chen, San-Nung, Chiang, An-Jen, Li, Ju-Yueh, Liou, Wen-Shiung, Lin, Li-Te, Tsai, Hsiao-Wen, Tsui, Kuan-Hao, Yen, Ming-Shyen, Chen, Jen-Ruei, Wang, Peng-Hui, Wen, Kuo-Chang, Chen, Yi-Jen, and Ng, Heung-Tat

Published
2016
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25. Uterine sarcoma Part II—Uterine endometrial stromal sarcoma: The TAG systematic review

Author

Chang, Yen-Hou, Chang, Yi, Chao, Hsiang-Tai, Chao, Kuan-Chong, Chuang, Chi-Mu, Ho, Chi-Hong, Huang, Chen-Yu, Hung, Zhi-Chen, Jiang, Ling-Yu, Lau, Hei-Yu, Li, Hsin-Yang, Lin, Chi-Yao, Liu, Chia-Hao, Sun, Pi-Lin, Twu, Nae-Fang, Wu, Hua-Hsi, Yu, Hann-Chin, Ju, Fong-Yuan, Tsai, Chih-Ping, Chang, Wen-Hsun, Hsu, Yen-Mei, Lee, Na-Rong, Chen, Chih-Yao, Chang, Ting-Chen, Chang, Wen-Chun, Chen, Chii-Hou, Chen, Ruey-Jian, Chow, Song-Nan, Lien, Yih-Ron, Sheu, Bor-Ching, Torng, Pao-Ling, Yen, Men-Luh, Lee, Wen-Ling, Wang, Kuan-Chin, Chang, Chih-Long, Chen, Chih-Ping, Chen, Jen-Ruei, Chen, Tze-Chien, Huang, Jian-Pei, Huang, Ming-Chao, Wang, Yeou-Lih, Chang, Cheng-Chang, Liu, Jah-Yao, Su, Her-Young, Wang, Yu-Chi, Yu, Mu-Hsien, Huang, Lee-Wen, Seow, Kok-Min, Lai, Tsung-Hsuan, Lee, Fa-Kung, Chen, Ching-Hui, Huang, Ben-Shian, Hsiao, Sheng-Mou, Sun, Hsu-Dong, Wu, Wen-Yih, Teng, Sen-Wen, Chen, Kuo-Hu, Hung, Jeng-Hsiu, Lai, Hung-Cheng, Yuan, Chiou-Chung, Hsieh, Ching-Hung, Wang, Chin-Jung, Chang, Shing-Jyh, Hung, Man-Jung, Hsu, Shih-Tien, Ke, Yu-Min, Lu, Chien-Hsing, Sun, Lou, Chang, Wei-Chun, Hung, Yao-Ching, Lin, Wu-Chou, Wang, Po-Hui, Chen, Tze-Ho, Li, Yiu-Tai, Wu, Meng-Hsing, Huang, Kuo-Feng, Fu, Hung-Chun, Chen, San-Nung, Chiang, An-Jen, Li, Ju-Yueh, Lin, Li-Te, Tsai, Hsiao-Wen, Tsui, Kuan-Hao, Horng, Huann-Cheng, Wen, Kuo-Chang, Wang, Peng-Hui, Chen, Yi-Jen, Yen, Ming-Shyen, and Ng, Heung-Tat

Published
2016
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26. Uterine sarcoma Part I—Uterine leiomyosarcoma: The Topic Advisory Group systematic review

Author

Chang, Yen-Hou, Chang, Yi, Chao, Hsiang-Tai, Chao, Kuan-Chong, Chuang, Chi-Mu, Ho, Chi-Hong, Huang, Chen-Yu, Hung, Zhi-Chen, Jiang, Ling-Yu, Lau, Hei-Yu, Li, Hsin-Yang, Lin, Chi-Yao, Liu, Chia-Hao, Sun, Pi-Lin, Twu, Nae-Fang, Wu, Hua-Hsi, Yu, Hann-Chin, Ju, Fong-Yuan, Tsai, Chih-Ping, Chang, Wen-Hsun, Hsu, Yen-Mei, Lee, Na-Rong, Chen, Chih-Yao, Chang, Ting-Chen, Chang, Wen-Chun, Chen, Chii-Hou, Chen, Ruey-Jian, Chow, Song-Nan, Lien, Yih-Ron, Sheu, Bor-Ching, Torng, Pao-Ling, Yen, Men-Luh, Lee, Wen-Ling, Wang, Kuan-Chin, Chang, Chih-Long, Chen, Chih-Ping, Chen, Jen-Ruei, Chen, Tze-Chien, Huang, Jian-Pei, Huang, Ming-Chao, Wang, Yeou-Lih, Chang, Cheng-Chang, Liu, Jah-Yao, Su, Her-Young, Wang, Yu-Chi, Yu, Mu-Hsien, Huang, Lee-Wen, Seow, Kok-Min, Lai, Tsung-Hsuan, Lee, Fa-Kung, Chen, Ching-Hui, Huang, Ben-Shian, Hsiao, Sheng-Mou, Sun, Hsu-Dong, Wu, Wen-Yih, Teng, Sen-Wen, Chen, Kuo-Hu, Hung, Jeng-Hsiu, Lai, Hung-Cheng, Yuan, Chiou-Chung, Hsieh, Ching-Hung, Wang, Chin-Jung, Chang, Shing-Jyh, Hung, Man-Jung, Hsu, Shih-Tien, Ke, Yu-Min, Lu, Chien-Hsing, Sun, Lou, Chang, Wei-Chun, Hung, Yao-Ching, Lin, Wu-Chou, Wang, Po-Hui, Chen, Tze-Ho, Li, Yiu-Tai, Wu, Meng-Hsing, Huang, Kuo-Feng, Fu, Hung-Chun, Chen, San-Nung, Chiang, An-Jen, Li, Ju-Yueh, Lin, Li-Te, Tsai, Hsiao-Wen, Tsui, Kuan-Hao, Wen, Kuo-Chang, Horng, Huann-Cheng, Wang, Peng-Hui, Chen, Yi-Jen, Yen, Ming-Shyen, and Ng, Heung-Tat

Published
2016
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31. Additional file 1 of Additional single dose GnRH agonist during luteal phase support may improve live birth rate in GnRHa-HRT frozen–thawed embryo transfer cycle: a retrospective cohort study

Author

Chang, Wei-Shan, Lin, Pei-Hsuan, Li, Chia-Jung, Chern, Chyi-Uei, Chen, Yu-Chen, Lin, Li-Te, and Tsui, Kuan-Hao

Abstract

Additional file 1: Supplementary Table 1. Subgroup analysis (Day 3 or Day 5 embryo transfer) of patients undergoing the GnRHa-HRT protocol with or without luteal GnRHa administration.

Published
2023
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40. Abnormal Uterine Bleeding in Perimenopausal Women: The Role of Hysteroscopy and Its Impact on Quality of Life and Sexuality

Author

Vitale, Salvatore Giovanni, primary, Watrowski, Rafał, additional, Barra, Fabio, additional, D’Alterio, Maurizio Nicola, additional, Carugno, Jose, additional, Sathyapalan, Thozhukat, additional, Kahramanoglu, Ilker, additional, Reyes-Muñoz, Enrique, additional, Lin, Li-Te, additional, Urman, Bulent, additional, Ferrero, Simone, additional, and Angioni, Stefano, additional

Published
2022
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47. Supplemental Material, sj-pdf-1-ccx-10.1177_1073274820976671 - Multi-Omics Analysis Identifying Key Biomarkers in Ovarian Cancer

Author

Ju-Yueh Li, Chia-Jung Li, Lin, Li-Te, and Kuan-Hao Tsui

Subjects
FOS: Clinical medicine, fungi, 111299 Oncology and Carcinogenesis not elsewhere classified
Abstract

Supplemental Material, sj-pdf-1-ccx-10.1177_1073274820976671 for Multi-Omics Analysis Identifying Key Biomarkers in Ovarian Cancer by Ju-Yueh Li, Chia-Jung Li, Li-Te Lin and Kuan-Hao Tsui in Cancer Control

Published
2020
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