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Your search keyword '"Lin, Jih-Hui"' showing total 38 results
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38 results on '"Lin, Jih-Hui"'

1. Human Bocavirus Circulating in Patients with Acute Gastroenteritis in Taiwan, 2018–2022.

Author

Chiu, Shu-Chun, Yu, Ya-Chun, Hsieh, Lun-Hao, Chen, Yu-Hua, Lu, Yu-An, Chang, Jen-Hung, and Lin, Jih-Hui

Abstract

Human bocavirus (HBoV) has been identified as a viral agent with a global presence, especially in young patients with gastrointestinal infections. In this study, we aimed to evaluate the epidemiological patterns of the HBoVs associated with acute gastroenteritis (AGE) in Taiwan. A total of 2994 AGE fecal samples from several diarrhea outbreaks from 2018 to 2022 were analyzed. From the samples, 73 positive samples were detected in three different bocaviruses: 30 (41.1%) were from HBoV1; 37 (50.7%) were from HBoV2; and 6 (8.2%) were from HBoV3, revealing the respective prevalences in AGE of 1%, 1.2%, and 0.2%. HBoV1 and HBoV2 were the two major epidemic agents of HBoVs in Taiwan during this study period and have seasonal distinct patterns with an epidemic peak from October to the following March. Phylogeny reconstruction and evaluation were implemented in Mega X; the results revealed that most HBoV1 strains in Taiwan appeared to be closely related to those strains from other Asian countries. The HBoV2 exhibited substantial genetic diversity and the HBoV3 genes showed discordance of groups. [ABSTRACT FROM AUTHOR]

Published
2024
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3. Global Trends in Norovirus Genotype Distribution among Children with Acute Gastroenteritis

Author

Cannon, Jennifer L., Bonifacio, Joseph, Bucardo, Filemon, Buesa, Javier, Bruggink, Leesa, Chan, Martin Chi-Wai, Fumian, Tulio M., Giri, Sidhartha, Gonzalez, Mark D., Hewitt, Joanne, Lin, Jih-Hui, Mans, Janet, Munoz, Christian, Pan, Chao-Yang, Pang, Xiao-Li, Pietsch, Corinna, Rahman, Mustafiz, Sakon, Naomi, Selvarangan, Rangaraj, Browne, Hannah, Barclay, Leslie, and Vinje, Jan

Subjects
Norovirus -- Distribution -- Identification and classification -- Genetic aspects, Gastroenteritis -- Statistics -- International aspects, Communicable diseases in children -- Statistics -- International aspects, RNA virus infections -- Statistics -- International aspects, Pediatric research, Company distribution practices, Health
Abstract

Globally, noroviruses are associated with [approximately equal to] 20% of acute gastroenteritis (AGE) cases, causing an estimated 685 million episodes and 210,000 deaths each year (2,2). By 2 years of [...]

Published
2021
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13. Detection of SARS-associated coronavirus in throat wash and saliva in early diagnosis

Author

Wang, Wei-Kung, Chen, Shey-Ying, Liu, I-Jung, Chen, Yee-Chun, Chen, Hui-Ling, Yang, Chao-Fu, Chen, Pei-Jer, Yeh, Shiou-Hwei, Kao, Chuan-Liang, Huang, Li-Min, Hsueh, Po-Ren, Wang, Jann-Tay, Sheng, Wang-Hwei, Fang, Chi-Tai, Hung, Chien-Ching, Hsieh, Szu-Min, Su, Chan-Ping, Chiang, Wen-Chu, Yang, Jyh-Yuan, Lin, Jih-Hui, Hsieh, Szu-Chia, Hu, Hsien-Ping, Chiang, Yu-Ping, Wang, Jin-Town, Yang, Pan-Chyr, and Chang, Shan-Chwen

Subjects
Coronavirus infections -- Development and progression, Coronavirus infections -- Control, Severe acute respiratory syndrome -- Development and progression, Severe acute respiratory syndrome -- Control
Abstract

The severe acute respiratory syndrome-associated coronavirus (SARS-CoV) is thought to be transmitted primarily through dispersal of droplets, but little is known about the load of SARS-CoV in oral droplets. We [...]

Published
2004

14. Serologic and molecular biologic methods for SARS-associated coronavirus infection, Taiwan

Author

Wu, Ho-Sheng, Chiu, Shu-Chun, Tseng, Tsan-Chang, Lin, Szu-Fong, Lin, Jih-Hui, Hsu, Yu-Fen, Wang, Mei-Ching, Lin, Tsuey-Li, Yang, Wen-Zieh, Ferng, Tian-Lin, Huang, Kai-Hung, Hsu, Li-Ching, Lee, Li-Li, Yang, Jyh-Yuan, Chen, Hour-Young, Su, Shun-Pi, Yang, Shih-Yan, Lin, Ting-Hsiang, and Su, Ih-Jen

Abstract

Severe acute respiratory syndrome (SARS) has raised a global alert since March 2003. After its causative agent, SARS-associated coronavirus (SARS-CoV), was confirmed, laboratory methods, including virus isolation, reverse transcriptase-polymerase chain [...]

Published
2004

19. Evaluation of a New Norovirus Genogroups GI and GII In VitroMolecular Diagnostic Assay Using Clinical Specimens Collected from Acute Diarrheal Outbreaks

Author

Chiu, Shu-Chun, Hu, Szu-Chieh, Liao, Ling-Min, Chen, Yu-Hua, Liao, Hui-Wen, Cheng, Ju-Chien, and Lin, Jih-Hui

Abstract

Norovirus is a leading cause of acute gastroenteritis (AGE) in Taiwan. To improve diagnosis as part of laboratory surveillance, AGE surveillance was conducted using a new fluorescent probe hydrolysis-based insulated isothermal polymerase chain reaction (PCR) method, the POCKIT system, and the results were compared with those obtained from conventional methods. A total of 119 clinical stool samples from reported AGE outbreaks were collected for this study. From 83 real-time reverse transcription PCR (rRT-PCR) norovirus-positive cases, the POCKIT system identified 78 with a sensitivity of 90.3% in GI genogroup and 96.7% in GII genogroup. The specificity for both GI and GII genogroups was 100%. Overall, the POCKIT system is faster and easier to use than the conventional rRT-PCR method, and because of its high sensitivity and specificity, this system is a promising alternative for the detection of norovirus in patients with AGE, and would benefit public health laboratories for near real-time surveillance of AGE epidemic outbreaks.

Published
2022
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21. Challenges and Strategies of Laboratory Diagnosis for Newly Emerging Influenza Viruses in Taiwan: A Decade after SARS

Author

Lin, Jih-Hui and Wu, Ho-Sheng

Subjects
Article Subject
Abstract

Since the first case of severe acute respiratory syndrome (SARS) in Taiwan was identified in March 2003, viral respiratory infections, in particular the influenza virus, have become a national public health concern. Taiwan would face a serious threat of public health problems if another SARS epidemic overlapped with a flu outbreak. After SARS, the Taiwan Centers for Disease Control accelerated and strengthened domestic research on influenza and expanded the exchange of information with international counterparts. The capacity of influenza A to cross species barriers presents a potential threat to human health. Given the mutations of avian flu viruses such as H7N9, H6N1, and H10N8, all countries, including Taiwan, must equip themselves to face a possible epidemic or pandemic. Such preparedness requires global collaboration.

Published
2015
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22. Presence of Human Bocavirus 1 in Hospitalised Children with Acute Respiratory Tract Infections in Latvia and Lithuania / Cilvēka Bokavīrusa 1 Klātbūtne Latvijā Un Lietuvā Hospitalizētiem Bērniem Ar Akūtām Elpceīu Slimībām

Author

Nora-Krūkle, Zaiga, primary, Rasa, Santa, additional, Vilmane, Anda, additional, Grāvelsiņa, Sabīne, additional, Kālis, Mārtiņš, additional, Ziemele, Inga, additional, Naciute, Milda, additional, Petraitiene, Sigita, additional, Mieliauskaite, Diana, additional, Klimantaviciene, Migle, additional, Girkontaite, Irute, additional, Liu, Hsin-Fu, additional, Lin, Jih-Hui, additional, Lin, Yung-Cheng, additional, Chan, Hsiu-Chuan, additional, Gardovska, Dace, additional, and Murovska, Modra, additional

Published
2016
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28. Evaluation of Influenza Virus A/H3N2 and B Vaccines on the Basis of Cross-Reactivity of Postvaccination Human Serum Antibodies against Influenza Viruses A/H3N2 and B Isolated in MDCK Cells and Embryonated Hen Eggs

Author

Kishida, Noriko, primary, Fujisaki, Seiichiro, additional, Yokoyama, Masaru, additional, Sato, Hironori, additional, Saito, Reiko, additional, Ikematsu, Hideyuki, additional, Xu, Hong, additional, Takashita, Emi, additional, Tashiro, Masato, additional, Takao, Shinichi, additional, Yano, Takuya, additional, Suga, Tomoko, additional, Kawakami, Chiharu, additional, Yamamoto, Miwako, additional, Kajiyama, Keiko, additional, Saito, Hiroyuki, additional, Shimada, Shin'ichi, additional, Watanabe, Sumi, additional, Aoki, Satomi, additional, Taira, Katsuya, additional, Kon, Miyako, additional, Lin, Jih-Hui, additional, and Odagiri, Takato, additional

Published
2012
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33. Laboratory-Based Surveillance and Molecular Epidemiology of Influenza Virus in Taiwan

Author

Shih, Shin-Ru, primary, Chen, Guang-Wu, additional, Yang, Ching-Chun, additional, Yang, Weng-Zhi, additional, Liu, Ding-Ping, additional, Lin, Jih-Hui, additional, Chiu, Shu-Chun, additional, Chen, Haur-Young, additional, Tsao, Kuo-Chien, additional, Huang, Chung-Guei, additional, Huang, Ya-Ling, additional, Mok, Chee-Keng, additional, Chen, Chi-Jene, additional, Lin, Tzou-Yien, additional, Wang, Jen-Ren, additional, Kao, Chuan-Liang, additional, Lin, Kwei-Hsian, additional, Chen, Li-Kuang, additional, Eng, Hock-Liew, additional, Liu, Yung-Ching, additional, Chen, Po-Yen, additional, Lin, Jen-Shiou, additional, Wang, Jen-Hsien, additional, Lin, Cheng-Wen, additional, Chan, Yu-Jiun, additional, Lu, Jang-Jih, additional, Hsiung, Chao A., additional, Chen, Pei-Jer, additional, and Su, Ih-Jen, additional

Published
2005
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36. Polycyclic aromatic hydrocarbon-DNA and protein adducts in coal tar treated patients and controls and their relationship to gluthathione S-transferase genotype

Author

Santella, Regina M., primary, Perera, Frederica P., additional, Lan Young, Tie, additional, Zhang, Yu-Jing, additional, Chiamprasert, Sinnabhatr, additional, Tang, Deliang, additional, Wen Wang, Lian, additional, Beachman, Agnes, additional, Lin, Jih-Hui, additional, and DeLeo, Vincent A., additional

Published
1995
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37. Isolation of influenza viruses and influenza epidemics in Taiwan, 1999–2002

Author

Lin, Jih-Hui, Chiu, Shu-Chun, Su, Iung-Ruei, and Chen, Hour-Young

Subjects
*INFLUENZA viruses, *EPIDEMICS, *ANTIGENS
Abstract

The Center for Disease Control established a surveillance system to monitor the activities of influenza viruses and their antigenic variation. Specimens were collected from patients under either outpatient or hospital care in all medical centers and teaching hospitals, as well as patients of the 300 more sentinel clinics throughout the country. Cell culture and IFA method were used to identify influenza virus, and assessment of the subtypes of influenza viruses was done using the WHO Influenza Diagnostic Kit. A total 2821 influenza viruses were isolated, 56.04% were type A and 43.96% were type B. Infection in the northern and eastern parts of the country was usually 2–3 weeks ahead of the middle and southern parts. Analyzing the antigenic variation of isolates, in the winter of 1999/2000, we found primarily A (H1N1), type B in 2000/2001, and A (H1N1) again in 2001/2002. During the last three flu seasons, type B showed more antigenic variation in Taiwan. Long-term surveillance can, in addition to informing the World Health Organization of the selection of vaccine strains, detect the mutation of indigenous influenza virus types in Taiwan. [Copyright &y& Elsevier]

Published
2004
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38. Nasopharyngeal shedding of severe acute respiratory syndrome-associated coronavirus is associated with genetic polymorphisms.

Author

Chen WJ, Yang JY, Lin JH, Fann CS, Osyetrov V, King CC, Chen YM, Chang HL, Kuo HW, Liao F, and Ho MS

Subjects
Adult, Aged, Female, Fibrinogen genetics, Humans, Interleukin-1 genetics, Interleukin-18 genetics, Logistic Models, Male, Middle Aged, Multivariate Analysis, Transcription Factor RelB genetics, Viral Load, Nasopharynx virology, Polymorphism, Genetic, Severe acute respiratory syndrome-related coronavirus physiology, Virus Shedding genetics
Abstract

Background: A high initial or peak severe acute respiratory syndrome (SARS)-associated coronavirus (SARS-CoV) load in nasopharyngeal specimens was shown to be associated with a high mortality rate. Because all infected individuals were devoid of preeexisting protective immunity against SARS-CoV, the biological basis for the variable virus burdens in different patients remains elusive., Methods: The nationwide SARS database in Taiwan was analyzed, and genotyping of 281 single-nucleotide polymorphisms (SNPs) of 65 genes was performed for 94 patients with SARS, to identify SNPs for which distribution between patients with or without detectable nasopharyngeal shedding of SARS-CoV was biased., Results: Titers of SARS-CoV shed in nasopharyngeal specimens varied widely, ranging from nondetectable to 10(8) SARS-CoV RNA copies/mL, and they were correlated positively with a high mortality rate (P<.0001, by trend test) and with early death (i.e., death occurring within 2 weeks of the onset of illness) (P=.0015, by trend test). Virus shedding was found to be higher among male patients (P=.0014, by multivariate logistic regression) and among older patients (P=.015, by multivariate logistic regression). Detectable nasopharyngeal shedding of SARS-CoV was associated with polymorphic alleles of interleukins 18 (P=.014) and 1A (P=.031) and a member of NF kappa B complex (reticuloendotheliosis viral oncogene homolog B [RelB]) (P=.034), all of which are proinflammatory in nature, as well as the procoagulation molecule fibrinogen-like protein 2 (P=.008)., Conclusion: The SARS-CoV load is a determinant of clinical outcomes of SARS, and it is associated with polymorphisms of genes involved in innate immunity, which might be regulated in an age- and sex-dependent manner. The findings of the present study provided leads to genes involved in the host response to SARS-CoV infection; if substantiated with functional studies, these findings may be applicable to other newly emerged respiratory viruses (e.g., the influenza pandemic strain).

Published
2006
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