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17 results on '"Lin, Jiaxu"'

4. Understanding Macrophage‐Tumor Interactions: Insights from Single‐Cell Behavior Monitoring in a Sessile Microdroplet System.

Author

Lin, Jiaxu, Zhang, Qiang, Xie, Tianze, Wu, Zengnan, Hou, Ying, Song, Yang, Lin, Yongning, and Lin, Jin‐Ming

Subjects
*CONTROLLED fusion, *MICRODROPLETS, *TUMOR microenvironment, *IMMUNE response, *MACROPHAGES
Abstract

Interaction between tumor‐associated macrophages and tumor cells is crucial for tumor development, metastasis, and the related immune process. However, the macrophages are highly heterogeneous spanning from anti‐tumorigenic to pro‐tumorigenic, which needs to be understood at the single‐cell level. Herein, a sessile microdroplet system designed for monitoring cellular behavior and analyzing intercellular interaction, demonstrated with macrophage‐tumor cell pairs is presented. An automatic procedure based on the inkjet printing method is utilized for the precise pairing and co‐encapsulation of heterotypic cells within picoliter droplets. The sessile nature of microdroplets ensures controlled fusion and provides stable environments conducive to adherent cell culture. The nitric oxide generation and morphological changes over incubation are explored to reveal the complicated interactions from a single‐cell perspective. The immune response of macrophages under distinct cellular microenvironments is recorded. The results demonstrate that the tumor microenvironment displays a modulating role in polarizing macrophages from anti‐tumorigenic into pro‐tumorigenic phenotype. The approach provides a versatile and compatible platform to investigate intercellular interaction at the single‐cell level, showing promising potential for advancing single‐cell behavior studies. [ABSTRACT FROM AUTHOR]

Published
2024
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17. Research on the Relationship between the Performance of China's Open-end Funds and Investors' Behavior

Author

Lin Jiaxu, Fan Gaole, and Kuang Zheju

Subjects
Finance, Profit (accounting), Index (economics), business.industry, Net capital rule, Financial market, Open-end fund, Business, Investor behavior, China, Investment (macroeconomics)
Abstract

Compared with closed-end funds, open-end funds refer to funds that can be traded jointly. With the development of financial market, fund has become an important investment channel. Fund performance reflects the historical growth, net capital and profit information of the fund, and it is also a reference index for investors to invest. The research shows that fund performance and investor behavior play an interactive role, with affecting the decision-making of investors' purchase or redemption. This paper mainly studies the relationship between the performance of open-end funds and investors' behavior, so as to make people more clearly about the relationship between the performance of open-end funds and investors' behavior.

Published
2021

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