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It may be possible to enhance adults' cognitive health and promote healthy aging through processing speed training using the Useful Field of View (UFOV) related activities and software. This study investigated the impact of utilizing UFOV on processing speed improvement in older adults in response to the growing global attention on cognitive health and aging issues. In this quasi-experimental study, 22 individuals (mean age ± SD = 71.9 ± 4.8) participated in the experimental group, and 20 community-based participants (mean age ± SD = 67.1 ± 4.8) were in the control group. The intervention involved ten sessions of UFOV training, each lasting 60 min, conducted twice a week for the experimental group while the control group engaged in volunteer service activities. Measurements of Counting Back, Fabrica, Double-Decision, and Hawkeye were administered to all participants before and after the intervention. The results showed significant improvements in the experimental group for the four measurements (p ≤ 0.01, 0.05, 0.001, 0.001) and non-significant gains in the control group (p ≥ 0.05) for all. Furthermore, mixed repeated-measures ANOVA analysis, with time 1 pre-test measures as the covariate, revealed significant interaction effects between time and group for all measurement indicators (p = 0.05, 0.01, 0.05) except for Fabrica (p > 0.05). In conclusion, these findings support the effectiveness of UFOV cognitive training interventions in enhancing specific cognitive abilities. [ABSTRACT FROM AUTHOR]

Background: Cancer is a major cause of death, and its early identification and intervention have potential for clinical actionability and benefits for human health. The studies using whole‐genome sequencing (WGS) and large samples analysis of cancer‐related genes have been rarely done. Methods: We performed WGS to explore germline mutations in coding and non‐coding areas of cancer‐related genes and non‐coding driver genes and regulatory areas. Structural variants (SVs) was also analyzed. We used several tools and a subgrouping method to analyze the variants in 1491 healthy participants. Moreover, 275 cancer‐related genes sequencing was carried out in 125 cancer patients. Results: The incidence of familial cancer in the Taiwanese general population is 8.79% (131/1491). Cancer carrier rate of cancer‐related genes is about 7.04% (105/1491) for pathogenic/likely pathogenic variants (P/LP) on ClinVar database only, and 28.24% (421/1491) for P/LP and loss of function variants. The carrier frequencies of cancer‐related genes P/LP on ClinVar database were as follows: 8.40% (11/131), 7.11% (28/394), and 6.83% (66/966) in FC, 1MC, and nMC, respectively. The SVs and non‐coding driver gene variants are uncommon. There are 1.54% (23/1491) of actionable cancer genes in American College of Medical Genetics and Genomics (ACMG), and the germline mutation rate of 275 cancer‐related genes is 7.2% (9/125) in cancer patients including 4.0% (5/125) of actionable cancer genes in ACMG. After analyzing the frequencies of P/LP variants on GJB2 and SLC25A13 genes, we suggest that these two genes may not be cancer‐related genes and need be re‐evaluated. Conclusions: WGS analysis can completely detect germline mutations in cancer carriers. This study use subgrouping approach for samples provides a strategy to study whether a gene or variant is a cancer‐related gene or variant in the future studies. [ABSTRACT FROM AUTHOR]

The initial views of community empowerment were considered residents as the subject for construction in the city and town. Because the development of city and town also increased tourism, in recent years residents have been encouraged to remodel with new styles and features. This study tries to explore the driving forces for the development of urban and rural/town tourism. The findings will allow stakeholders (residents, tourists, sojourners, and government) to reexamine the future for the development of urban and rural tourism and to rediscover new value-driving forces by the urban and rural/town tourism development. This study defines an evaluation system of urban and rural tourism by four aspects: cultural preservation, environment sustentation, economic development, and social consciousness. This study adopts the integrated MCDM approach to evaluate the SDI (Sustainable Development Index) for urban and rural/town tourism based on the five tourist towns in northern Taiwan. The research findings will help authorities understand the competitive advantages of tourism in each location and draw up development strategies for urban and rural/town tourism based on the common value of stakeholders. This study also proposes new viewpoints and tourist highlights to help stakeholders identify the next generation for tourism in urban and rural areas. [ABSTRACT FROM AUTHOR]

Music festival events are now hosted all over Taiwan and attract thousands of visitors every year, creating a massive need for festival tourism. These music festival events not only invite composers to demonstrate their musical creations. But also they assist many independent bands realizing their musical dreams. This study analyzes how to influence the event image of music festival events for event participants. And it explores how factors that affect the tourist experience and enhance the event image related to this kind of activity. This study used four aspects to build a development strategies map utilizing the DEMATEL technique for the music festival events and establishes the group components of the PCA technique and then adopts the ANP technique to evaluate the aspects/components' weights. Finally, the VIKOR technique was utilized to assess the competitive performance of the music festival events. The research reveals that the PP (package price) and SP (site planning) are primary influencers for music festival events. The event service providers can improve their promotional strategies by the NRM (network relation map) technique. This research provides recommendations for service providers to enhance their equipment plans and service experiences for music festival events. [ABSTRACT FROM AUTHOR]

Traditionally, package tour (PT) agencies assumed that tourists only pay attention to the PT's price, so PT service providers often offer limited package tours based on options and prices. Nowadays, PT service providers face the difficult challenge of how to offer diverse PTs to satisfy tourists' needs based on a reasonable price. This study proposes an evaluation model of package tours based on diverse resources and transportation means. This study proposes a two-dimensional evaluation framework to analyse tourists' needs regarding package tour services and the proposed model could be applied to plan mass customized package tours based on the portfolio of value satisfaction index (VSI) and the price satisfaction index (PSI). The study also proposes that mass customized package tours can improve the traditional tour planning method through a portfolio of diverse tourism resources. Moreover, the study integrates the different choices of traffic and transportation tools, as well as tourism resources and providers in six portfolios of package tours in the Nantou county of Taiwan. These six package tours can be planned through three traffic and transportation tools (tourist coach, railroad, and minibus) and four tourism resources (natural experiences, cultural exploration, shopping and cuisine, and event participation). [ABSTRACT FROM AUTHOR]