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1. Effect of theophylline on sleep-disordered breathing in heart failure

Author

Javaheri, S., Parker, T.J., Wexler, L., Liming, J.D., Lindower, P., and Roselle, G.A.

Subjects
Sleep apnea syndromes -- Drug therapy, Theophylline -- Evaluation
Abstract

Theophylline may be effective in restoring normal breathing patterns in patients with heart failure. These patients often stop breathing periodically during sleep, a condition called apnea. Fifteen men with heart failure and sleep apnea took theophylline twice a day or placebo for five days and then switched treatments. Theophylline reduced the number of apnea episodes and also the percent of time the men experienced low blood oxygen levels.

Published
1996

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