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1. Urographie

Author

Limberg, B., Kauffmann, G. W., Rau, W. S., Roeren, T., and Sartor, K.

Published
1995
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5. American Society of Colon and Rectal Surgeons 91st Annual Convention Podium and Poster abstracts: June 7–12, 1992 San Francisco, CA

Author

Lechner, P., Lind, P., Binter, G., Golub, R. W., Kerner, B. A., Wise, Jr., W. E., Meesig, D. M., Hartmann, R. F., Khanduja, K. S., Sayre, J. W., Aguilar, P. S., Guillem, J. G., Forde, K. A., Treat, M. R., Neugut, A. I., O'Toole, K. M., Diamond, B. E., Kewenter, J., Brevinge, H., Haglind, E., Limberg, B., Elles, C. N., Boggs, W. H., Slagle, G. H., Cole, P. A., Coyle, D. J., Smith, L. E., Orkin, B., Saclarides, T. J., Sheridan, W. G., Lowndes, R. H., Young, H. L., Wong, W. D., Rothenberger, D. A., Bartolo, D. C. C., Wexner, S. D., Ger, G. C., Jorge, J. M. N., Lee, E., Nogueras, J. J., Jagelman, D. G., McKenna, K., Koltun, W. A., Bute, B., Lichliter, W., Le, T., Timmcke, A., Gathright, J. B., Mascagni, D., Hojo, K., Moriya, Y., Sugihara, K., Di, G., Zenni, G. C., Abraham, K., Dobrin, P. B., Harford, F. J., Suzuki, K., Gunderson, L., Devine, R. M., Dozois, R. R., Cavaliere, F., Pemberton, J. H., Fazio, V., Cosimelli, M., Beart, R. W., Giannarelli, D., Moran, M., Ramos, A., Rothenberger, D., Goldberg, S., Antonenko, D., Heymen, S., Gulledge, A. D., Jakate, S., Saclarides, T., Heine, J. A., Williams, J. G., VanBergen, E. H., Buie, W. D., Goldberg, S. M., Davies, N., Yates, J., Jenkins, S. A., Taylor, B. A., Bapat, B., Stern, H., Berk, T., Parker, J., Ray, P. N., McLeod, R., Cohen, Z., Rowe, J. K., Zera, R. T., Madoff, R. D., Bubrick, M. P., Roberts, J. C., Johnston, G. R., Fenney, D. A., Farouk, R., Duthie, G. S., McCue, J. L., Phillips, R. K. S., Viamonte, M., Cole, J., Gottesman, L., Solomon, M. J., McLeod, R. S., Kern, K., Jensen, L. L., Lowry, A. C., Vernava, III, A. M., Longo, W. E., Daniel, G. L., Ehrenpreis, E., Stone, J. M., Cosman, B. C., Wolfe, V. A., Nino-Murcia, M., Perkash, I., Marcello, P. W., Roberts, P. L., Schoetz, Jr., D. J., Murray, J. J., Coller, J. A., Veidenheimer, M. C., Keighley, M. R. B., Grobler, S. P., Hosie, K. B., Schmitt, S. L., James, K., Lucas, F., Peck, Donald A., Ferrara, A., Grotz, R. L., Perry, R. E., Hanson, R. B., Lewis, W. G., Holdsworth, P. J., Sagar, P. M., Johnston, D., Perry, T. G., Strong, S. A., Fazio, V. W., Lavery, I. C., Oakley, J. R., Church, J. M., Milsom, J. W., Fozard, J. B. J., Nelson, H., Schneebaum, S., Arnold, M. W., Young, D., LaValle, G. J., Petty, L., Berens, A., Mojizisik, C., Martin, E. W., Hase, K., Shatney, C. H., Trollope, M., Johnson, D., Vierra, M., Deutsch, A. A., Tulchinsky, H., Nudelman, I., Gutman, H., Reiss, R., Taylor, Brian M., Araujo, A., Bleday, R., Jessurun, J., Heine, J., Rosen, Les, Sipe, Paul, Riether, Robert, Stasik, John, Sheets, James, Khubchandani, Indru, Reiter, W., Friedberg, G., Morey, G., Goldstein, E., Williamson, P., Larach, S., Senagore, A. J., Luchtefeld, M. A., MacKeigen, J. M., Mazier, W. P., Wengert, T., Ott, M. T., Bailey, H. R., Hartendorp, P., Dailey, T. H., Church, J. C., Johansen, O. B., Daniel, N., Korst, M., Kuijpers, H. C., Pena, J. P., Christenson, C. E., Balcos, E. G., Lewis, W., Mitchell, C., MacFie, J., Hildebrandt, U., Ecker, K. W., Kraus, J., Schmid, T., Feifel, G., Tjandra, J. J., Scoggin, Steve, Frazee, Richard C., Ambroze, Jr., W. L., Nezhat, C., Pennington, E., Nezhat, F., Stolfi, V. M., Thorson, A. G., Falk, P. M., Fitzgibbons, Jr, R. J., Luukkonen, P., Järvinen, H. J., James, E., Paty, P. B., Enker, W. E., Cohen, A. M., Lauwers, G. Y., Saad, R., Birnbaum, E., DeVos, W., Fry, R., Kodner, I., Fleshman, J., Cali, R. L., Pitsch, R. M., Blatchford, G. J., Christensen, M. A., Schroeder, T. K., Easley, K. A., Ellis, C. N., Cheape, J. D., Hull, T. L., Salanga, V., Kokoszka, Joseph, Andrianopoulos, Georgia, Nelson, Richard, Abcarian, Herand, Kumar, D., Benson, M. J., Roberts, J., Martin, J. E., Swash, M., Wingate, D. L., Williams, N. S., Orkin, B. A., Emsellem, H., Dent, John, Tissaw, M. A., Shafik, A., Abel, M. E., Chiu, Y. S. Y., Russell, T. R., Volpe, P. A., Casillas, G. L., Mashas, W. E., Eastman, D. A., Grace, R. H., Anderson, J. M., Hacker, K., Heryer, J., Conner, W., Rubin, R., Eisenstat, T., Salvati, E., Oliver, G., Duberman, E., Simmang, C. L., Fry, R. D., Kodner, I. J., Fleshman, J. W., Corman, M. L., Galandiuk, S., Weiner, G. J., Kahn, D., Mitchell, E., Abdel-Nabi, H., Block, G. E., Mannella, E., Tedesco, M., Anza, M., Civalleri, D., Di Tora, P., Capussotti, L., Morandi, G. B., Tirelli, C., Da Pian, P. P., Cortesi, E., Ruggeri, E., Fitzgerald, S. D., Davis, Faith, Bowen, Phyllis, Sutter, Eileen, Kikendall, Walter, McGannon, E., Brantley, P. A., Czyrko, C., Falardeau, C., Trepashko, Don, Skosey, John, Michelassi, F., Staniunas, R. J., Vignati, P. V., Beck, D. E., Karulf, R., Roettger, R., Braidt, J., Ruoff, K., Ackroyd, F., Shellito, P., Goh, H. S., Lin, L. W., Edwards, E., Farmer, J., Walters, C. A., Hyman, N. H., Hebert, J. C., Richman, Irving M., Staren, E. D., Sessions, S. C., Scoma, R. S., Clements, B., Smink, Jr., R. D., Arai, K., Sugita, A., Yamazaki, Y., Harada, H., Fukushima, T., Armstrong, D. N., Ballantyne, G. H., Sillin, L. F., Davie, R. J., Harding, L. K., Birch, N. J., Yamanouchi, T., Bayer, I., Mitmaker, B., Gordon, P. H., Wang, E., Kynaston, H., Edelstein, P. S., Thompson, S. M., Davies, R. J., Farmer, K. C. R., Oliver, S. E., Spigelman, A. D., Bennett, P., O'Kelly, T. J., Brading, A. F., Mortensen, N. J., Paul, P., McGannon, E. M., Huth, P., Hull-Boiner, S., Pezim, M. E., Johnson, H. W., Gillespie, K. D., Willard, P., Owen, D. A., Ramsey, P. S., Leu, S. Y., Hsu, H., Al-Humadi, Adil H., Eisman, E., Tries, J., Gupta, N. C., Frick, M. P., Boman, B. M., Franceschi, D., Eckhauser, M. L., Pritchard, T., Konsten, J., Baeten, C. G. M. I., Havenith, M. G., Soeters, P. B., Lau, P. W. K., Lorentz, T. G., Wong, J., and The III In-CYT-103 Immunoscintigraphy Study Group

Published
1992
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6. 90th Annual Convention Poster Presentations and Abstracts

Author

Ellis, C. N., Coyle, D. J., Boggs, H. W., Slagle, G. W., Cole, P. A., Kuramoto, S., Ihara, O., Oohara, T., Nichols, J., Opelka, F., Gathright, J. B., Green, J. B., Poulard, J. B., Ott, A., Bank, S., Margolis, I. B., Meagher, A., Stuart, M., Heine, J. A., Rothenberger, D. A., Nemer, F. D., Christenson, C. E., Saad, R. C., Church, J. M., Fazio, V. W., Lavery, I. C., Oakley, J. R., Milsom, J. W., Schroeder, T. K., Påhlman, L., Frykholm, G., Glimelius, B., Kashtan, H., Papa, M., Wilson, B., Stern, H., Zelnick, R., Haas, P., Ajlouni, M., Fox, T., Szilagy, E., Cummings, B. J., Fleshman, J. W., Dreznick, Z., Fry, R. D., Kodner, I. J., Perry, R. E., Pemberton, J. H., Litchy, W. L., Ferrara, A., Levin, K. E., Hanson, R. B., Cali, R. L., Blatchford, G. J., Thorson, A. G., Christenson, M. A., Pitsch, R. M., Jensen, L. L., Lowry, A. C., Keighley, M. R. B., Oya, M., Oritz, J., Pinho, M., Asperer, J., Chattaphaday, G., Baeten, C., Konsten, J., Spaans, F., Soeters, P., Habets, A., Schouten, W. R., Ruseler van Embden, J. G. H., Auwerda, J. J. A., Sagar, P. M., Goodwin, P., Holdsworth, P. J., Johnston, D., Bundy, C. A., Jacobs, D. M., Bubrick, M. P., Kashiwagi, H., Konishi, F., Kanazawa, K., Woodland, D. O., Saclarides, T. J., Bapna, M. S., Kubota, Y., Sunouchi, K., Ono, M., Muto, T., Masaki, T., Suzuki, K., Adachi, M., Wong, W. D., Goldberg, S. M., Wexner, S. D., Daniel, N., Jagelman, D. G., Christiansen, J., Rasmussen, O., Zhu, B. -W., Williams, J. G., Schottler, J. L., Heyman, S., Marchetti, F., Timmcke, A. E., Hicks, T. C., Ray, J. E., Bernstein, M. A., Madoff, R. D., Caushaj, P. F., Zarbo, R. J., Ma, C. K., Shida, H., Yamamoto, T., Machida, T., Imanari, T., Wang, J. Y., You, Y. T., Tang, R. P., Chen, J. S., Chang-Chien, C. R., Sugihara, K., Hojo, K., Moriya, Y., Hasegawa, H., Krueger, B., Warren, W., Faber, L. P., Abel, M. E., Chiu, Y. S. Y., Russell, T. R., Volpe, P. A., Frazee, R. C., Roberts, J., Symmonds, S., Snyder, S., Hendricks, J., Smith, R., Merchant, N., Hashmi, H., Scalea, T., Whelan, R., Longo, W. E., Gusberg, B. J., Ballantyne, G. H., Davidson, T., Allen-Mersh, T. G., Gazzard, B., Miles, A. J. G., Wastell, C., Viponde, M., Stotter, A., Miller, R. F., Fieldman, N., Slack, W. W., Tjandra, J., Savoca, P. E., Flannery, J. T., Modlin, I. M., Tsukada, K., Tazawa, K., Lavery, E. C., Voeller, G. R., Bunch, G., Britt, L. G., Neto, J. A. Reis, Quilici, F. A., Cordeiro, F., Reis, Jr, J. A., Wojcik, J. B., Banerjee, S. R., Walters, D. L., Cherry, D. A., Bleday, R., Pena, J. P., Buls, J. G., Pascual, R., Tripodi, G., Padmanabhan, A., Schouter, W. R., Blankensteijn, J. D., Moenning, S., Huber, P., Simonton, C., Odom, C., Kaplan, E., Nightengale, S., Shah, P. C., Hashami, H. F., Kottmeier, P., Velcek, F., Klotz, D., Whelan, R. L., Sher, M. E., Bauer, J. J., Gelernt, I., Launer, D. P., Gerber, A., Nogueras, J. J., Finne, C. O., Sohn, N., Weinstein, M. A., Lugo, R. N., Eisenberg, M. M., Tsao, J., Galandiuk, S., Tuckson, W. B., Strong, S., Oakey, J. R., Ambroze, W. L., Dozois, R. R., Carpenter, H. A., Kartheuser, A. H., LaRusso, N. F., Wiesner, R. H., Ilstrup, D. M., Schleck, C. D., Ambroze, W., Beart, R., Dozois, R., Wolff, B., Pemberton, J., Kelly, K., Devine, R., Nivatvongs, S., Metzger, P., Phillips, S. F., Zinmeister, A. R., Pezim, M. E., Vignati, P., Cohen, J., Stahl, T. J., Roberts, P. L., Schoetz, Jr., D. J., Murray, J. J., Coller, J. A., Veidenheimer, M. C., Yamazaki, Y., Ribeiro, M. B., Sachar, D., Heimann, T. M., Aufses, A. H., Greenstein, A. J., Stryker, S. J., Green, D., McLeod, R. S., Cohen, Z., Cullen, J., Greenberg, G. R., Ho, C. S., Reznick, R., Wolff, B. G., Cangemi, J., Carryer, P., Jeejeebhoy, K. N., MacCarty, R., Weilland, L., Senagore, A. J., MacKeigan, J. M., Guillem, J., Ondrula, D. P., Prasad, M. L., Nelson, R. L., Abcarian, H., Coughlin, R. J., Corman, M. L., Prager, E. D., Borison, D. I., Bloom, A. D., Pritchard, T. J., McGannon, E., Sivak, M. V., van Stolk, R., Hull-Boiner, S., Milson, J. W., Sullivan, M., Rosato, G. O., Jorge, J. M., Durdey, P., Kennedy, M. J., Oster, M., Murray, J., Cirocco, W. C., Rusin, L. C., Brown, A. C., Reilly, J. C., Cataldo, P., Luchtefeld, M. A., Mazier, W. P., Wolkomir, A. F., Ruiz-Moreno, F., Alvarado-Cerna, R., Rodriguez, U., Amaro, J., Kerner, B. A., Oliver, G. C., Eisenstat, T. E., Rubin, R. J., Salvati, E. P., Dominguez, J. M., Coon, J. S., Weinstein, R. S., Kameyama, M., Fukuda, I., Imaoka, S., Iwanga, T., Kyzer, S., Mitmaker, B., Gordon, P. H., Wang, E., Grace, R. H., Gibbons, P., Scott, K. M. W., Berger, A., Mischinger, H. J., Arian-Schad, K., Davis, M., Miller, D., Fielding, L. P., Begin, L. R., Bell, A. M., Shafik, A., Abdel-Moneim, K., Khalid, A., Devine, R. M., Beart, Jr., R. W., Melton, L. J., Ngoi, S. S., Chia, J., Goh, P., Sim, E., Godwin, P., Quirke, P., Barrett, R. C., Koltun, W. A., Smith, R. J., Loehner, D., Roberts, P., Veidenheimer, M., Schoetz, D., Chattopadhyay, G., Kumar, D., Hosie, K., Kmiot, W., Mostaf, A., Tulley, N., Harding, I., Falcone, R. E., Wanamaker, S., Santanello, S. A., Carey, L. C., Rivera, D. E., Durdley, P., Gross, P. T., Sarles, J. C., Arnaud, A., Sielezneff, I., Orsoni, P., Joly, A., Limberg, B., Stolfi, V. M., Lavery, I., Oakley, J., Church, J., Fazio, V., Asbun, H. J., Castellanos, H., Asbun, J., Franko, E. R., Ivatury, R. R., Schwalb, D., Saad, R., Schroeder, T., Reis, Jr., J. A., Dziki, A. J., Duncan, M. D., Harmon, J. W., Saini, N., Malthaner, R. A., Fernicola, M. T., Hakki, F. Z., Trad, K. S., Ugarte, R. M., Ryan, P., Chang, H. R., Chavoshan, B., Barsoum, G., Bonardi, R., Scaramelo, A., Possebon, A., Peres, C., Röhrig, C., Kappas, A. M., Ortiz, J., Fan, H. A., Milsom, J., Lechner, P., Lind, P., Cesnik, H., Venkatesh, K. S., Larson, D. M., Morrison, D. N., Ramanujam, P. J., Rubbini, M., Mascoli, F., Mari, C., Bresadola, V., and Donini, I.

Published
1991
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9. Stoffwechsel II

Author

Kather, H., Wieland, E., Fischer, B., Wirth, A., Hauner, H., Feick, P., Löffler, G., Häussinger, D., Sies, H., Gerok, W., Limberg, B., Kommerell, B., Lea, O., von Bergmann, K., Gnasso, A., Augustin, J., Miehlke, Klaus, editor, and Bergmann, J. F.

Published
1984
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10. Hepatologie II

Author

Junge, U., Friedl, P., Staritz, M., Ewe, K., Meyer zum Büschenfelde, K.-H., Räth, U., Zuna, I., Schlaps, D., Limberg, B., Lorenz, A., van Kaick, G., Lorenz, W. J., Kommerell, B., Hoensch, H., Schreyer, I., Pott, G., Rauterberg, J., Schneider, M., Högemann, B., Eberhardt, G., Gerlach, U., Miehlke, Klaus, editor, and Bergmann, J. F.

Published
1984
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11. Hepatologie

Author

Gmelin, K., Doerr, H. W., Stecher, J., Sann, G., Kommerell, B., Brattig, N. W., Hausch, F., Henning, H., Berg, P. A., Poralla, T., Hütteroth, T. H., Meyer zum Büschenfelde, K.-H., Hess, G., Arnold, W., Drescher, M., Ohlen, J., Korb, G., Selmair, H., Köhler, H., Renschin, G., Pausch, J., Rasenack, J., Häussinger, D., Gerok, W., Theilmann, L., Stollman, Y. R., Arias, I. M., Wolkoff, A. W., André, M., Hoensch, H., Limberg, B., Leimenstoll, G., Kamenisch, W. R., Moch, K. J., Homann, J., Matthes, K. J., Rössle, M., Herz, R., Lehmann, G., Luft, M., Egberts, E.-H., Hamster, W., Schomerus, H., Jürgens, P., Pape, G. R., Rieber, E. P., Eisenburg, J., Lohmeyer, J., Hoffmann, R., Thoenes, G. H., Knapp, W., Riethmüller, G., Nagai, S., Manns, M., Schultheiß, H.-P., Berg, P.-A., Klingenberg, M., Weckenmann, U., Weber, P., Stechemesser, E., Klöppel, G., Dancygier, H., Schneider, M., Leuschner, U., Hübner, K., Classen, M., Högemann, B., Pott, G., Voss, B., Rauterberg, J., Gerlach, U., Sixel, F., Doss, M., and Schlegel, Bernhard, editor

Published
1982
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12. Diagnostik entzündlicher und tumoröser Dickdarmveränderungen durch Kolonsonographie

Author

Limberg B

Subjects
medicine.medical_specialty, medicine.diagnostic_test, biology, business.industry, food and beverages, Colonoscopy, Lumen (anatomy), Connective tissue, General Medicine, biology.organism_classification, Gastroenterology, digestive system diseases, Caecum, medicine.anatomical_structure, Internal medicine, medicine, Large intestine, Inflammatory infiltration, business, Pathological
Abstract

By water instillation into the large intestine, sonographic visualization of the whole length of the colon from the recto-sigmoid to the caecum can be achieved. Detailed evaluation of the lumen, the wall and the surrounding connective tissue may be carried out. Diagnostic sonography of the colon in 41 patients with pathological changes confirmed by colonoscopy showed that colonic polyps and carcinomas can be detected by this method. In Crohn's disease, typical changes can be seen, which allow the degree of inflammatory infiltration to be assessed. Thus, sonography of the colon is a diagnostic procedure which gives discriminating evidence in diseases of the large intestine.

Published
2008

13. Differentialdiagnose akut entzündlicher Dickdarmerkrankungen durch Kolonsonographie

Author

Limberg B

Subjects
medicine.medical_specialty, Pathology, medicine.diagnostic_test, business.industry, Acute ulcerative colitis, General Medicine, Disease, medicine.disease, Ulcerative colitis, Gastroenterology, digestive system diseases, Cecum, medicine.anatomical_structure, Internal medicine, Biopsy, Medicine, Large intestine, Differential diagnosis, business
Abstract

Colon sonography enables imaging of the colon from the beginning of the rectosigmoid transition up to the cecum. Colon sonographic investigations in 29 patients (normal findings n = 15, ulcerative colitis n = 6, Crohn's disease n = 8) with a finding verified by coloscopy and biopsy show that acute ulcerative colitis and florid Crohn's disease lead to different sonographic alterations. Formation of haustra can no longer be detected in the two diseases. In Crohn's disease, the typical sonographically discernible wall layering has been abolished, and the wall is markedly thickened. In contrast to this, the wall layering is preserved in acute ulcerative colitis and the wall is only moderately thickened. The results show that differential diagnosis of acute inflammatory diseases of the large intestine is possible using colon sonography.

Published
2008

14. Diagnostik von Dickdarmtumoren durch Kolonsonographie*

Author

Limberg B

Subjects
medicine.medical_specialty, Percutaneous, medicine.diagnostic_test, business.industry, Ultrasound, Colonoscopy, Echogenicity, Gastroenterology, digestive system diseases, medicine.anatomical_structure, Internal medicine, medicine, Radiology, Nuclear Medicine and imaging, Large intestine, Radiology, Prospective cohort study, business
Abstract

Retrograde instillation of liquid into the colon allows a specific, percutaneous sonographic examination of the colon to be performed. As part of a prospective study of the diagnosis of colonic tumors in 260 patients, this form of colon sonography was examined together with colonoscopy. Sonographically, colonic polyps and carcinomas of the colon manifested as echogenic, parietal masses. Using colonic sonography, it was possible to identify 96% of the carcinomas that had been diagnosed colonoscopically. The sonographic diagnosis of polyps was insufficient if they were smaller than 6 mm: if they were larger than 7 mm, however, diagnostic sensitivity was 91%. The results of this study show that colon sonography is a new, sensitive method in the diagnosis of colonic tumors.

Published
2008

16. Hydrokolonsonographie - Möglichkeiten und Grenzen einer sonographischen Diagnostik von Dickdarmerkrankungen

Author

Limberg B

Subjects
Pathology, medicine.medical_specialty, Crohn's disease, Virtual colonoscopy, medicine.diagnostic_test, business.industry, Colorectal cancer, Gastroenterology, Lumen (anatomy), Invagination, medicine.disease, Ulcerative colitis, digestive system diseases, 030218 nuclear medicine & medical imaging, 3. Good health, 03 medical and health sciences, Cecum, 0302 clinical medicine, medicine.anatomical_structure, Medicine, 030211 gastroenterology & hepatology, Large intestine, Radiology, business
Abstract

Hydrocolonic sonography - potentials and limitations of ultrasonographic diagnosis of colon diseases. Ultrasonic examination has become increasingly important in the diagnosis of diseases of the gastrointestinal tract. In neoplastic diseases of the large intestine, however, the diagnostic value of conventional transabdominal sonography is limited. The sonographic evaluation of the colon could be improved by the retrograde instillation of water into the colon in a procedure called hydrocolonic sonography. This technique allows the visualization of the colon sonographically from the rectosigmoid transition to the cecum. Hydrocolonic sonography enables a detailed sonographic examination of the hypoechoic colonic lumen, the five individual layers of the colon wall and the surrounding connective tissue, thus providing additional information and allowing a more precise diagnosis of many diseases of the colon. Colonic polyps and carcinomas appear sonographically as echogenic structures projecting from the intestinal wall into the lumen. Colonic polyps larger than 7 mm in diameter and carcinomas of the colon can be detected with great sensitivity. In addition, detailed evaluation of the structure of the bowel wall permits more precise staging of tumors of the colon. Aside from such localized changes, hydrocolonic sonography can also demonstrate changes in the wall structure in chronic inflammatory large bowel diseases such as Crohn's disease and ulcerative colitis. In addition hydrocolonic sonography has been proven to be of great value for the ultrasonographically-guided hydrostatic reduction of intussusception in children. On the other hand virtual colonoscopy is another promising new imaging method for the diagnosis of colon diseases. The differences between hydrcolonic sonography and virtual colonoscopy and their potential for screening purposes of colon cancer will be discussed.

Published
2001

28. Lanceolate hair-J (lahJ): A mouse model for human hair disorders.

Author

Sundberg, J. P., Boggess, D., Bascom, C., Limberg, B. J., Shultz, L. D., Sundberg, B. A., King, Jr, L. E., and Montagutelli, X.

Subjects
HAIR diseases, ANIMAL models in research
Abstract

Lanceolate hair-J (lahJ) arose spontaneously in 1994 on the DBA/1LacJ inbred background at The Jackson Laboratory. Mutant mice were runted, alopecic, and lacked vibrissae. As they aged, their skin wrinkled. Affected mice developed a noninflammatory, proliferative skin disease with follicular dystrophy. Hair fibers developed a number of abnormalities including periodic nodules along the shaft (trichorrhexis nodosa), compaction resembling trichorrhexis invaginata, spiral fractures, broken tips, and lance-shaped tips. This mutation exhibits some characteristics that resemble an autosomal recessive ichthyosiform disease that occurs in humans characterized in part by peculiar, invaginating, multinodal, hair shaft abnormalities known as Netherton's syndrome. Periodic nodules also resemble the human genetic based disease monilethrix. This autosomal recessive mouse mutation, allelic with lanceolate hair (lah), based on breeding studies, is located on mouse Chromosome 18, within a cluster of genes coding for adhesion molecules. Homozygotes for either of these allelic mouse mutations have elevated serum IgE levels, a feature also common with human Netherton's syndrome. [ABSTRACT FROM AUTHOR]

Published
2000
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32. Histologic differential diagnosis of focal liver lesions by ultrasonically guided fine needle biopsy.

Author

Limberg, B, Höpker, W W, and Kommerell, B

Abstract

Ultrasonically guided fine needle biopsies were carried out in 84 patients with focal liver lesions and were subsequently evaluated histologically. A correct diagnosis of malignancy was made in 46 of 52 patients with proven hepatic malignancy, showing an overall accuracy of 93%. The specificity of the procedure was 100%. Such histological examination not only enables the differentiation between primary and secondary hepatic malignancy; it has the additional advantage of making a more precise tumour description and at the same time it pinpoints the primary site of the tumour. [ABSTRACT FROM PUBLISHER]

Published
1987

33. Correction of altered plasma amino acid pattern in cirrhosis of the liver by somatostatin.

Author

Limberg, B and Kommerell, B

Abstract

The purpose of our study was to evaluate the effect of somatostatin (500 microgram/h intravenously) upon insulin, c-peptide, glucagon and plasma amino acids concentrations in patients with and without cirrhosis of the liver. The typical plasma amino acid pattern in cirrhosis is characterised by increased concentrations of the aromatic amino acids and decreased concentrations of the branched chain amino acids and of alanine and glycine. After administration of somatostatin insulin, c-peptide and glucagon concentrations decreased and those of the branched chain amino acids in both groups increased; in addition in patients with cirrhosis the plasma concentrations of threonine, serine, glycine, alanine, lysine, and arginine increased also. Infusion of somatostatin plus insulin in patients with cirrhosis succeeded in preventing the increase in the branched chain amino acid concentrations, while the infusion of somatostatin plus glucagon decreased threonine, serine, glycine, alinine, phenylalanine, tyrosine, lysine and arginine concentrations. It is therefore suggested that the effect of somatostatin on the plasma amino acids may be because of the reduction of insulin and glucagon concentrations; however, other effects of somatostatin cannot be excluded at present. [ABSTRACT FROM PUBLISHER]

Published
1984

35. Vascular endothelial growth factor receptor-2 and neuropilin-1 form a receptor complex that is responsible for the differential signaling potency of VEGF(165) and VEGF(121).

Author

Whitaker, G B, Limberg, B J, and Rosenbaum, J S

Abstract

The two most abundant secreted isoforms of vascular endothelial growth factor A (VEGF(165) and VEGF(121)) are formed as a result of differential splicing of the VEGF-A gene. VEGF(165) and VEGF(121) share similar affinities at the isolated VEGF receptor (VEGFR)-2 but have been previously demonstrated to have differential ability to activate VEGFR-2-mediated effects on endothelial cells. Herein we investigate whether the recently described VEGF(165) isoform-specific receptor neuropilin-1 (Npn-1) is responsible for the difference in potency observed for these ligands. We demonstrate that although VEGFR-2 and Npn-1 form a complex, this complex does not result in an increase in VEGF(165) binding affinity. Therefore, the differential activity of VEGF(165) and VEGF(121) cannot be explained by a differential binding affinity for the complex. Using an antagonist that competes for VEGF(165) binding at the VEGFR-2.Npn-1 complex, we observe specific antagonism of VEGF(165)-meditated phosphorylation of VEGFR-2 without affecting the VEGF(121) response. These data indicate that the formation of the complex is responsible for the increased potency of VEGF(165) versus VEGF(121). Taken together, these data suggest a receptor-clustering role for Npn-1, as opposed to Npn-1 behaving as an affinity-converting subunit.

Published
2001
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36. [Coincidence of primary sclerosing cholangitis and sarcoidosis--case report and review of the literature]

Author

Keller K, Wj, Hofmann, Kayser K, Limberg B, Lippert J, Werner A, Andrassy K, Hahn P, Wolfgang Stremmel, and Pr, Galle

Subjects
Adult, Diagnosis, Differential, Male, Liver, Sarcoidosis, Pulmonary, Biopsy, Cholangitis, Sclerosing, Humans, Lung
Abstract

Primary sclerosing cholangitis (PSC) and sarcoidosis are diseases of unknown etiology which are rarely associated. Here we report the case of a 31-year-old man with PSC and pulmonary sarcoidosis. In addition, we include a brief review on PSC and sarcoidosis, in particular with respect to etiopathogenesis and diagnosis.

41. [Hydrocolonic sonography--potentials and limitations of ultrasonographic diagnosis of colon diseases].

Author

Limberg B

Subjects
Colon diagnostic imaging, Humans, Sensitivity and Specificity, Ultrasonography, Colonic Diseases diagnostic imaging, Colonic Neoplasms diagnostic imaging, Colonic Polyps diagnostic imaging, Image Enhancement
Abstract

Hydrocolonic sonography - potentials and limitations of ultrasonographic diagnosis of colon diseases. Ultrasonic examination has become increasingly important in the diagnosis of diseases of the gastrointestinal tract. In neoplastic diseases of the large intestine, however, the diagnostic value of conventional transabdominal sonography is limited. The sonographic evaluation of the colon could be improved by the retrograde instillation of water into the colon in a procedure called hydrocolonic sonography. This technique allows the visualization of the colon sonographically from the rectosigmoid transition to the cecum. Hydrocolonic sonography enables a detailed sonographic examination of the hypoechoic colonic lumen, the five individual layers of the colon wall and the surrounding connective tissue, thus providing additional information and allowing a more precise diagnosis of many diseases of the colon. Colonic polyps and carcinomas appear sonographically as echogenic structures projecting from the intestinal wall into the lumen. Colonic polyps larger than 7 mm in diameter and carcinomas of the colon can be detected with great sensitivity. In addition, detailed evaluation of the structure of the bowel wall permits more precise staging of tumors of the colon. Aside from such localized changes, hydrocolonic sonography can also demonstrate changes in the wall structure in chronic inflammatory large bowel diseases such as Crohn's disease and ulcerative colitis. In addition hydrocolonic sonography has been proven to be of great value for the ultrasonographically-guided hydrostatic reduction of intussusception in children. On the other hand virtual colonoscopy is another promising new imaging method for the diagnosis of colon diseases. The differences between hydrcolonic sonography and virtual colonoscopy and their potential for screening purposes of colon cancer will be discussed.

Published
2001
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42. [Diagnosis of chronic inflammatory bowel disease by ultrasonography].

Author

Limberg B

Subjects
Abscess diagnostic imaging, Abscess etiology, Colitis, Ulcerative diagnostic imaging, Colonic Diseases diagnostic imaging, Colonic Diseases etiology, Crohn Disease complications, Crohn Disease diagnostic imaging, Diagnosis, Differential, Humans, Ileal Diseases diagnostic imaging, Ileal Diseases etiology, Intestinal Fistula diagnostic imaging, Intestinal Fistula etiology, Ultrasonography, Doppler, Color, Ultrasonography, Doppler, Duplex, Inflammatory Bowel Diseases diagnostic imaging
Abstract

Abdominal sonography as a noninvasive diagnostic method has proven to be of great value in evaluating patients with chronic inflammatory bowel diseases. The ultrasound pattern of bowel inflammation is characterized by a thickened and hypoechoic inflamed bowel wall, which appears like a target on transverse scans. Both Crohn's disease and ulcerative colitis can be detected with great sensitivity by abdominal ultrasonography. Ultrasonography (u.s.) reveals the intra- and extramural spread of the inflammation. U.s. is suitable method for the detection of abdominal complications, such as fistulas, abscesses and strictures, especially in patients with Crohn's disease. Duplex and color Doppler ultrasonography are helpful in the detection of the splanchnic hemodynamic changes in patients with intestinal inflammation. This offers a noninvasive and indirect means of assessing disease activity. Both endorectal ultrasonography and MRT are the most sensitive methods to detect fistulas and abscesses in patients with Crohn's disease. Because of the diagnostic possibilities, the unstressful nature of the procedure and the general acceptance by the patients, next to endoscopy, ultrasonography is the most important diagnostic procedure both as a primary diagnostic imaging modality and for the follow-up of patients with inflammatory bowel diseases.

Published
1999

43. [Chronic recurrent multifocal osteomyelitis (CRMO). Diaphyseal attack with progressive hyperostosis].

Author

Schenk JP, Limberg B, Grauer A, and Kauffmann G

Subjects
Adolescent, Biopsy, Bone and Bones pathology, Chronic Disease, Humans, Male, Osteolysis diagnostic imaging, Osteolysis pathology, Radiography, Recurrence, Diaphyses pathology, Hyperostosis diagnostic imaging, Hyperostosis pathology, Osteomyelitis diagnostic imaging, Osteomyelitis pathology
Published
1998
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44. [Coincidence of primary sclerosing cholangitis and sarcoidosis--case report and review of the literature].

Author

Keller K, Hofmann WJ, Kayser K, Limberg B, Lippert J, Werner A, Andrassy K, Hahn P, Stremmel W, and Galle PR

Subjects
Adult, Biopsy, Cholangitis, Sclerosing diagnosis, Cholangitis, Sclerosing pathology, Diagnosis, Differential, Humans, Liver pathology, Lung pathology, Male, Sarcoidosis, Pulmonary diagnosis, Sarcoidosis, Pulmonary pathology, Cholangitis, Sclerosing complications, Sarcoidosis, Pulmonary complications
Abstract

Primary sclerosing cholangitis (PSC) and sarcoidosis are diseases of unknown etiology which are rarely associated. Here we report the case of a 31-year-old man with PSC and pulmonary sarcoidosis. In addition, we include a brief review on PSC and sarcoidosis, in particular with respect to etiopathogenesis and diagnosis.

Published
1997

45. [Ultrasound guided puncture of the portal vein in transjugular intrahepatic portasystemic stent shunt (TIPSS)].

Author

Roeren T, Richter GM, Limberg B, Jacoby IR, and Kauffmann GW

Subjects
Humans, Liver Cirrhosis surgery, Portal Vein surgery, Surgical Instruments, Treatment Outcome, Ultrasonography, Liver Cirrhosis diagnostic imaging, Portal Vein diagnostic imaging, Portasystemic Shunt, Transjugular Intrahepatic instrumentation, Punctures instrumentation
Abstract

Successful completion of a transjugular intrahepatic portosystemic stentshunt (TIPSS) relies on knowledge of the individual hepatic vascular anatomy. The patients referred for TIPSS have an increased risk of contrast-medium-induced renal failure, and therefore the potential for a complete angiographic work-up during the procedure is limited. The same patient population also carries an increased risk of bleeding, which necessitates a rather accurate guiding technique for portal punctures. We have established transcutaneous sonographic guidance as a standard technique for transjugular portal puncture, reducing complication rates and intervention time. Competing imaging modalities for guidance are discussed.

Published
1996
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46. [Rare fracture of the atlas after hyperextension trauma].

Author

Theobald I, Limberg B, and Kauffmann GW

Subjects
Cervical Atlas diagnostic imaging, Diagnosis, Differential, Female, Humans, Middle Aged, Cervical Atlas injuries, Spinal Fractures diagnostic imaging, Tomography, X-Ray Computed, Whiplash Injuries diagnostic imaging
Published
1996
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47. [Fulminant, fatal respiratory insufficiency in long-term immunosuppression after kidney transplantation].

Author

Theobald I, Limberg B, Magener A, and Kauffmann GW

Subjects
Adult, Azathioprine adverse effects, Fatal Outcome, Female, Humans, Immunologic Deficiency Syndromes chemically induced, Immunologic Deficiency Syndromes diagnostic imaging, Immunologic Deficiency Syndromes pathology, Lung pathology, Lung Neoplasms diagnostic imaging, Lung Neoplasms pathology, Postoperative Complications pathology, Prednisolone adverse effects, Pulmonary Embolism diagnostic imaging, Pulmonary Embolism pathology, Radiography, Respiratory Insufficiency pathology, Uterine Cervical Neoplasms pathology, Azathioprine administration & dosage, Kidney Transplantation pathology, Lung Neoplasms secondary, Neoplastic Cells, Circulating, Postoperative Complications diagnostic imaging, Prednisolone administration & dosage, Respiratory Insufficiency diagnostic imaging, Uterine Cervical Neoplasms diagnostic imaging
Published
1995

48. Diagnosis and differential diagnosis of ulcerative colitis and Crohn's disease by hydrocolonic sonography.

Author

Limberg B and Osswald B

Subjects
Abdomen diagnostic imaging, Adult, Colitis, Ulcerative diagnosis, Colonoscopy, Crohn Disease diagnosis, Diagnosis, Differential, Female, Humans, Male, Middle Aged, Prospective Studies, Sensitivity and Specificity, Ultrasonography, Colitis, Ulcerative diagnostic imaging, Colon diagnostic imaging, Crohn Disease diagnostic imaging
Abstract

Objectives: The entire length of the colon, starting at the rectosigmoid junction and ending at the cecum, can be visualized by transabdominal sonography after retrograde water instillation into the colon. By this method, termed hydrocolonic sonography, it is possible to evaluate in detail the lumen, the colon wall, and the surrounding tissue. Five layers of different echogenicity can be differentiated within the colon wall., Methods: In a prospective study of 440 patients, we compared the value of conventional abdominal sonography and hydrocolonic sonography with that of colonoscopy, in the diagnosis and differential diagnosis of ulcerative colitis and colonic Crohn's disease., Results: In 93% of patients with Crohn's disease, the normal five-layer structure of the colonic wall was no longer in evidence, and the wall appeared hypoechogenic and clearly thickened. In contrast, in patients with ulcerative colitis, the five-layer structure could clearly be discerned, and although the colon wall remained hypoechogenic, it was only moderately thickened. Colonic Crohn's disease and ulcerative colitis were detectable by hydrocolonic sonography, with a sensitivity of 96% and 91%, respectively, whereas the sensitivity achieved by conventional abdominal sonography was only 71% and 62%, respectively. Furthermore, hydrocolonic sonography made possible the differentiation of Crohn's disease from ulcerative colitis in 93% of the cases., Conclusion: This new diagnostic procedure could thus advantageously be introduced for the diagnosis, differential diagnosis, and follow-up of patients with chronic inflammatory large bowel diseases.

Published
1994

49. [The metastases of an occult bronchial carcinoma in a transplanted kidney. A case report on the differential diagnosis of multiple space-occupying lesions in a transplanted kidney].

Author

Düx M, Wiesel M, Roeren T, Zeier M, and Limberg B

Subjects
Brain pathology, Brain Neoplasms pathology, Brain Neoplasms secondary, Carcinoma, Bronchogenic pathology, Diagnosis, Differential, Humans, Kidney diagnostic imaging, Kidney pathology, Kidney Neoplasms pathology, Kidney Transplantation diagnostic imaging, Lung pathology, Lung Neoplasms pathology, Male, Middle Aged, Radiography, Ultrasonography, Carcinoma, Bronchogenic secondary, Kidney Neoplasms secondary, Kidney Transplantation pathology, Lung Neoplasms secondary, Neoplasms, Unknown Primary pathology
Published
1994
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