350 results on '"Liepinsh, Edgars"'
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2. Knockout of Tmlhe in mice is not associated with autism spectrum disorder phenotypes or motor dysfunction despite low carnitine levels
3. Decreased long-chain acylcarnitine content increases mitochondrial coupling efficiency and prevents ischemia-induced brain damage in rats
4. Off‐target effects of statins: molecular mechanisms, side effects and the emerging role of kinases.
5. Hydroxymethylglutaryl‐CoA reductase activity is essential for mitochondrial β‐oxidation of fatty acids to prevent lethal accumulation of long‐chain acylcarnitines in the mouse liver.
6. Innovative Approach to Enhance Bioavailability of Birch Bark Extracts: Novel Method of Oleogel Development Contrasted with Other Dispersed Systems
7. Development of Potent Microtubule Targeting Agent by Structural Simplification of Natural Diazonamide.
8. Empagliflozin Protects Cardiac Mitochondrial Fatty Acid Metabolism in a Mouse Model of Diet-Induced Lipid Overload
9. High-resolution respirometry for measurement of fatty acid β-oxidation in brain mitochondria. A comparative study and application in ischemia and aging
10. Trimethylamine N-oxide impairs pyruvate and fatty acid oxidation in cardiac mitochondria
11. Metformin decreases bacterial trimethylamine production and trimethylamine N-oxide levels in db/db mice
12. Mitochondrial Function in the Kidney and Heart, but Not the Brain, is Mainly Altered in an Experimental Model of Endotoxaemia
13. Heart-Type Fatty Acid Binding Protein Binds Long-Chain Acylcarnitines and Protects against Lipotoxicity
14. Data on cardiac and vascular functionality in ex vivo and in vivo models following acute administration of trimethylamine N-oxide
15. Methyl-γ-butyrobetaine decreases levels of acylcarnitines and attenuates the development of atherosclerosis
16. Acylcarnitines in health and disease: biomarkers and drug targets
17. Binding versus Enzymatic Processing of ε-Trimethyllysine Dioxygenase Substrate Analogues
18. Suppression of intestinal microbiota-dependent production of pro-atherogenic trimethylamine N-oxide by shifting L-carnitine microbial degradation
19. Pharmacological activation of PPARβ/δ preserves mitochondrial respiratory function in ischemia/reperfusion via stimulation of fatty acid oxidation-linked respiration and PGC-1α/NRF-1 signaling
20. A cross-sectional survey of urinary iodine status in Latvia
21. The brain acylcarnitine profile depends on nutritional state
22. Acylcarnitines: Nomenclature, Biomarkers, Therapeutic Potential, Drug Targets, and Clinical Trials
23. Association of reduced glyoxalase 1 activity and painful peripheral diabetic neuropathy in type 1 and 2 diabetes mellitus patients
24. Troubleshooting digital macro photography for image acquisition and the analysis of biological samples
25. Rodent Heart and Brain Tissue Preparation for Digital Macro Photography after Ischemia-reperfusion
26. Review 1: Mitochondrial metabolites acylcarnitines: therapeutic potential and drug targets
27. Review 2: Mitochondrial metabolites acylcarnitines: therapeutic potential and drug targets
28. Mitochondrial metabolites acylcarnitines: therapeutic potential and drug targets
29. Acute and long‐term administration of palmitoylcarnitine induces muscle‐specific insulin resistance in mice
30. High l-carnitine concentrations do not prevent late diabetic complications in type 1 and 2 diabetic patients
31. Fasting-Mimicking Diet Reduces Trimethylamine N-Oxide Levels and Improves Serum Biochemical Parameters in Healthy Volunteers
32. Rodent Heart and Brain Tissue Preparation for Digital Macro Photography after Ischemia-reperfusion
33. Long-chain acylcarnitine content determines the pattern of energy metabolism in cardiac mitochondria
34. Administration of L-carnitine and mildronate improves endothelial function and decreases mortality in hypertensive Dahl rats
35. Protective Effects of Meldonium in Experimental Models of Cardiovascular Complications with a Potential Application in COVID-19
36. Low cardiac content of long-chain acylcarnitines in TMLHE knockout mice prevents ischaemia-reperfusion-induced mitochondrial and cardiac damage
37. Antibacterial activity of apramycin at acidic pH warrants wide therapeutic window in the treatment of complicated urinary tract infections and acute pyelonephritis
38. Inhibition of Fatty Acid Metabolism Increases EPA and DHA Levels and Protects against Myocardial Ischaemia-Reperfusion Injury in Zucker Rats
39. Metabolomic studies of experimental diabetic urine samples by 1H NMR spectroscopy and LC/MS method
40. IMproving Preclinical Assessment of Cardioprotective Therapies (IMPACT) criteria: guidelines of the EU-CARDIOPROTECTION COST Action
41. Activated peroxisomal fatty acid metabolism improves cardiac recovery in ischemia-reperfusion
42. A short-term high-dose administration of sodium pivalate impairs pyruvate metabolism without affecting cardiac function
43. Glyoxalase 1 and glyoxalase 2 activities in blood and neuronal tissue samples from experimental animal models of obesity and type 2 diabetes mellitus
44. Long-Chain Acylcarnitines Decrease the Phosphorylation of the Insulin Receptor at Tyr1151 Through a PTP1B-Dependent Mechanism
45. Mildronate decreases carnitine availability and up-regulates glucose uptake and related gene expression in the mouse heart
46. Comparative pharmacological activity of optical isomers of phenibut
47. Selective inhibition of OCTN2 is more effective than inhibition of gamma-butyrobetaine dioxygenase to decrease the availability of L-carnitine and to reduce myocardial infarct size
48. Myocardial Infarct Size-Limiting and Anti-Arrhythmic Effects of Mildronate Orotate in the Rat Heart
49. Mildronate, the inhibitor of l-carnitine transport, induces brain mitochondrial uncoupling and protects against anoxia-reoxygenation
50. Energy substrate metabolism and mitochondrial oxidative stress in cardiac ischemia/reperfusion injury
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