389 results on '"Lichtenstein D"'
Search Results
2. P16-40: Metabolic effects and half-life of organophosphate and pyrethroid pesticides and their metabolites in HepaRG cells
- Author
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Fritsche, K., primary, Lichtenstein, D., additional, Muñoz, C., additional, Garí, M., additional, Abass, K., additional, Grimalt, J.O., additional, and Braeuning, A., additional
- Published
- 2023
- Full Text
- View/download PDF
3. Psychology, behavioral economics, and public policy
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Amir, O, Ariely, D, Cooke, A, Dunning, D, Epley, N, Gneezy, U, Koszegi, B, Lichtenstein, D, Mazar, N, Mullainathan, S, Prelec, D, Shafir, E, and Silva, J
- Subjects
public policy ,psychology ,behavioral economics - Abstract
Economics has typically been the social science of choice to inform public policy and policymakers. In the current paper we contemplate the role behavioral science can play in enlightening policymakers. In particular, we provide some examples of research that has and can be used to inform policy, reflect on the kind of behavioral science that is important for policy, and approaches for convincing policy-makers to listen to behavioral scientists. We suggest that policymakers are unlikely to invest the time translating behavioral research into its policy implications, and researchers interested in influencing public policy must therefore invest substantial effort, and direct that effort differently than in standard research practices.
- Published
- 2005
4. Development of new approach methods for the identification and characterization of endocrine metabolic disruptors—a PARC project
- Author
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Braeuning, A., Balaguer, P., Bourguet, W., Carreras-Puigvert, J., Feiertag, K., Kamstra, J.H., Knapen, D., Lichtenstein, D., Marx-Stoelting, P., Rietdijk, J., Schubert, Kristin, Spjuth, O., Stinckens, E., Thedieck, K., van den Boom, R., Vergauwen, L., von Bergen, Martin, Wewer, N., Zalko, D., Braeuning, A., Balaguer, P., Bourguet, W., Carreras-Puigvert, J., Feiertag, K., Kamstra, J.H., Knapen, D., Lichtenstein, D., Marx-Stoelting, P., Rietdijk, J., Schubert, Kristin, Spjuth, O., Stinckens, E., Thedieck, K., van den Boom, R., Vergauwen, L., von Bergen, Martin, Wewer, N., and Zalko, D.
- Abstract
In past times, the analysis of endocrine disrupting properties of chemicals has mainly been focused on (anti-)estrogenic or (anti-)androgenic properties, as well as on aspects of steroidogenesis and the modulation of thyroid signaling. More recently, disruption of energy metabolism and related signaling pathways by exogenous substances, so-called metabolism-disrupting chemicals (MDCs) have come into focus. While general effects such as body and organ weight changes are routinely monitored in animal studies, there is a clear lack of mechanistic test systems to determine and characterize the metabolism-disrupting potential of chemicals. In order to contribute to filling this gap, one of the project within EU-funded Partnership for the Assessment of Risks of Chemicals (PARC) aims at developing novel in vitro methods for the detection of endocrine metabolic disruptors. Efforts will comprise projects related to specific signaling pathways, for example, involving mTOR or xenobiotic-sensing nuclear receptors, studies on hepatocytes, adipocytes and pancreatic beta cells covering metabolic and morphological endpoints, as well as metabolism-related zebrafish-based tests as an alternative to classic rodent bioassays. This paper provides an overview of the approaches and methods of these PARC projects and how this will contribute to the improvement of the toxicological toolbox to identify substances with endocrine disrupting properties and to decipher their mechanisms of action.
- Published
- 2023
5. P16-40: Metabolic effects and half-life of organophosphate and pyrethroid pesticides and their metabolites in HepaRG cells
- Author
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Fritsche, K., Lichtenstein, D., Muñoz, C., Garí, Mercè, Abass, K., Grimalt, Joan O., Braeuning, A., Fritsche, K., Lichtenstein, D., Muñoz, C., Garí, Mercè, Abass, K., Grimalt, Joan O., and Braeuning, A.
- Abstract
The human population is exposed to organophosphate and pyrethroid pesticides due to their extensive use in agriculture and household products. Once up-taken, these compounds are metabolized relatively quickly by cytochrome P450 enzymes and excreted via the urine. The measurement of a metabolite allows thus to identify its precursor compound. Some pesticides are suspected metabolism-disrupting chemicals (MDCs) and are associated, amongst others, with the onset of diabetes. Since validated test methods for the identification of MDCs are still lacking, the European Union is funding several projects that aim to develop and establish (pre-) validated test methods, one of the being EDCMET (Metabolic effects of endocrine disrupting chemicals: novel test methods and adverse outcome pathways). Here, we recently finalized an in vitro assay for hepatic triglyceride accumulation (TGA), which is currently under pre-validation with the PEPPER platform. This high-throughput assay uses the metabolically competent human hepatoma cell line HepaRG, known for its high expression of major cytochrome P450 enzymes, which is comparable to primary human hepatocytes. Using this assay, we already screened more than 100 compounds regarding their potential to induce steatosis in vitro and further extended our database including 12 organophosphate and pyrethroid pesticides and their metabolites, which we measured in urine and serum samples of different cohorts. In parallel to the TGA assay, we determined the half-life of both, the parent compound and metabolite, under the HepaRG treatment conditions aiming to clarify the contribution of either of them to the development of steatosis in vitro.
- Published
- 2023
6. Editors’ introduction
- Author
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Lichtenstein, D., primary
- Published
- 2018
- Full Text
- View/download PDF
7. P12-28 Test methods for metabolic effects of endocrine disrupting chemicals
- Author
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Fritsche, K., primary, Lichtenstein, D., additional, Luckert, C., additional, Lasch, A., additional, and Braeuning, A., additional
- Published
- 2022
- Full Text
- View/download PDF
8. ESICM LIVES 2016: part three: Milan, Italy. 1–5 October 2016
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Velasquez, T., Mackey, G., Lusk, J., Kyle, U. G., Fontenot, T., Marshall, P., Shekerdemian, L. S., Coss-Bu, J. A., Nishigaki, A., Yatabe, T., Tamura, T., Yamashita, K., Yokoyama, M., Ruiz-Rodriguez, J. C., Encina, B., Belmonte, R., Troncoso, I., Tormos, P., Riveiro, M., Baena, J., Sanchez, A., Bañeras, J., Cordón, J., Duran, N., Ruiz, A., Caballero, J., Nuvials, X., Riera, J., Serra, J., Rutten, A. M. F., van Ieperen, S. N. M., Der Kinderen, E. P. H. M., Van Logten, T., Kovacikova, L., Skrak, P., Zahorec, M., Kyle, U. G., Akcan-Arikan, A., Silva, J. C., Mackey, G., Lusk, J., Goldsworthy, M., Shekerdemian, L. S., Coss-Bu, J. A., Wood, D., Harrison, D., Parslow, R., Davis, P., Pappachan, J., Goodwin, S., Ramnarayan, P., Chernyshuk, S., Yemets, H., Zhovnir, V., Pulitano’, S. M., De Rosa, S., Mancino, A., Villa, G., Tosi, F., Franchi, P., Conti, G., Patel, B., Khine, H., Shah, A., Sung, D., Singer, L., Haghbin, S., Inaloo, S., Serati, Z., Idei, M., Nomura, T., Yamamoto, N., Sakai, Y., Yoshida, T., Matsuda, Y., Yamaguchi, Y., Takaki, S., Yamaguchi, O., Goto, T., Longani, N., Medar, S., Abdel-Aal, I. R., El Adawy, A. S., Mohammed, H. M. E. H., Mohamed, A. N., Parry, S. M., Knight, L. D., Denehy, L., De Morton, N., Baldwin, C. E., Sani, D., Kayambu, G., da Silva, V. Z. M., Phongpagdi, P., Puthucheary, Z. A., Granger, C. L., Rydingsward, J. E., Horkan, C. M., Christopher, K. B., McWilliams, D., Jones, C., Reeves, E., Atkins, G., Snelson, C., Aitken, L. M., Rattray, J., Kenardy, J., Hull, A. M., Ullman, A., Le Brocque, R., Mitchell, M., Davis, C., Macfarlane, B., Azevedo, J. C., Rocha, L. L., De Freitas, F. F. M., Cavalheiro, A. M., Lucinio, N. M., Lobato, M. S., Ebeling, G., Kraegpoeth, A., Laerkner, E., De Brito-Ashurst, I., White, C., Gregory, S., Forni, L. G., Flowers, E., Curtis, A., Wood, C. A., Siu, K., Venkatesan, K., Muhammad, J. B. H., Ng, L., Seet, E., Baptista, N., Escoval, A., Tomas, E., Agrawal, R., Mathew, R., Varma, A., Dima, E., Charitidou, E., Perivolioti, E., Pratikaki, M., Vrettou, C., Giannopoulos, A., Zakynthinos, S., Routsi, C., Atchade, E., Houzé, S., Jean-Baptiste, S., Thabut, G., Genève, C., Tanaka, S., Lortat-Jacob, B., Augustin, P., Desmard, M., Montravers, P., de Molina, F. J. González, Barbadillo, S., Alejandro, R., Álvarez-Lerma, F., Vallés, J., Catalán, R. M., Palencia, E., Jareño, A., Granada, R. M., Ignacio, M. L., Cui, N., Liu, D., Wang, H., Su, L., Qiu, H., Li, R., Jaffal, K., Rouzé, A., Poissy, J., Sendid, B., Nseir, S., Paramythiotou, E., Rizos, M., Frantzeskaki, F., Antoniadou, A., Vourli, S., Zerva, L., Armaganidis, A., Riera, J., Gottlieb, J., Greer, M., Wiesner, O., Martínez, M., Acuña, M., Rello, J., Welte, T., Atchade, E., Mignot, T., Houzé, S., Jean-Baptiste, S., Thabut, G., Lortat-Jacob, B., Tanaka, S., Augustin, P., Desmard, M., Montravers, P., Soussi, S., Dudoignon, E., Ferry, A., Chaussard, M., Benyamina, M., Alanio, A., Touratier, S., Chaouat, M., Lafaurie, M., Mimoun, M., Mebazaa, A., Legrand, M., Sheils, M. A., Patel, C., Mohankumar, L., Akhtar, N., Noriega, S. K. Pacheco, Aldana, N. Navarrete, León, J. L. Ávila, Baquero, J. Durand, Bernal, F. Fernández, Ahmadnia, E., Hadley, J. S., Millar, M., Hall, D., Hewitt, H., Yasuda, H., Sanui, M., Komuro, T., Kawano, S., Andoh, K., Yamamoto, H., Noda, E., Hatakeyama, J., Saitou, N., Okamoto, H., Kobayashi, A., Takei, T., Matsukubo, S., Rotzel, H. B., Lázaro, A. Serrano, Prada, D. Aguillón, Gimillo, M. Rodriguez, Barinas, O. Diaz, Cortes, M. L. Blasco, Franco, J. Ferreres, Roca, J. M. Segura, Carratalá, A., Gonçalves, B., Turon, R., Mendes, A., Miranda, F., Mata, P. J., Cavalcanti, D., Melo, N., Lacerda, P., Kurtz, P., Righy, C., Rosario, L. E. de la Cruz, Lesmes, S. P. Gómez, Romero, J. C. García, Herrera, A. N. García, Pertuz, E. D. Díaz, Sánchez, M. J. Gómez, Sanz, E. Regidor, Hualde, J. Barado, Hernández, A. Ansotegui, Irazabal, J. M. Guergué, Spatenkova, V., Bradac, O., Suchomel, P., Urli, T., Lazzeri, E. Heusch, Aspide, R., Zanello, M., Perez-Borrero, L., Garcia-Alvarez, J. M., Arias-Verdu, M. D., Aguilar-Alonso, E., Rivera-Fernandez, R., Mora-Ordoñez, J., De La Fuente-Martos, C., Castillo-Lorente, E., Guerrero-Lopez, F., Lesmes, S. P. Gómez, Rosario, L. E. De la Cruz, Pertuz, E. D. Díaz, Hernández, A. Ansotegui, Romero, J. C. García, Sánchez, M. J. Gómez, Herrera, A. N. García, Ramírez, J. Roldán, Sanz, E. Regidor, Hualde, J. Barado, León, J. P. Tirapu, Navarro-Guillamón, L., Cordovilla-Guardia, S., Iglesias-Santiago, A., Guerrero-López, F., Fernández-Mondéjar, E., Vidal, A., Perez, M., Juez, A., Arias, N., Colino, L., Perez, J. L., Pérez, H., Calpe, P., Alcala, M. A., Robaglia, D., Perez, C., Lan, S. K., Cunha, M. M., Moreira, T., Santos, F., Lafuente, E., Fernandes, M. J., Silva, J. G., Rosario, L. E. de la Cruz, Lesmes, S. P. Gómez, Herrera, A. N. García, Romero, J. C. García, Pertuz, E. D. Díaz, Sánchez, M. J. Gómez, Sanz, E. Regidor, Echeverría, J. G. Armando, Hernández, A. Ansotegui, Hualde, J. Barado, Podlepich, V., Sokolova, E., Alexandrova, E., Lapteva, K., Kurtz, P., Shuinotsuka, C., Rabello, L., Vianna, G., Reis, A., Cairus, C., Salluh, J., Bozza, F., Torres, J. C. Barrios, Araujo, N. J. Fernández, García-Olivares, P., Keough, E., Dalorzo, M., Tang, L. K., De Sousa, I., Díaz, M., Marcos-Zambrano, L. J., Guerrero, J. E., Gomez, S. E. Zamora, Lopez, G. D. Hernandez, Cuellar, A. I. Vazquez, Nieto, O. R. Perez, Gonzalez, J. A. Castanon, Bhasin, D., Rai, S., Singh, H., Gupta, O., Bhattal, M. K., Sampley, S., Sekhri, K., Nandha, R., Aliaga, F. A., Olivares, F., Appiani, F., Farias, P., Alberto, F., Hernández, A., Pons, S., Sonneville, R., Bouadma, L., Neuville, M., Mariotte, E., Radjou, A., Lebut, J., Chemam, S., Voiriot, G., Dilly, M. P., Mourvillier, B., Dorent, R., Nataf, P., Wolff, M., Timsit, J. F., Ediboglu, O., Ataman, S., Ozkarakas, H., Kirakli, C., Vakalos, A., Avramidis, V., Obukhova, O., Kurmukov, I. A., Kashiya, S., Golovnya, E., Baikova, V. N., Ageeva, T., Haritydi, T., Kulaga, E. V., Rios-Toro, J. J., Perez-Borrero, L., Aguilar-Alonso, E., Arias-Verdu, M. D., Garcia-Alvarez, J. M., Lopez-Caler, C., De La Fuente-Martos, C., Rodriguez-Fernandez, S., Sanchez-Orézzoli, M. Gomez, Martin-Gallardo, F., Nikhilesh, J., Joshi, V., Villarreal, E., Ruiz, J., Gordon, M., Quinza, A., Gimenez, J., Piñol, M., Castellanos, A., Ramirez, P., Jeon, Y. D., Jeong, W. Y., Kim, M. H., Jeong, I. Y., Ahn, M. Y., Ahn, J. Y., Han, S. H., Choi, J. Y., Song, Y. G., Kim, J. M., Ku, N. S., Shah, H., Kellner, F., Rezai, F., Mistry, N., Yodice, P., Ovnanian, V., Fless, K., Handler, E., Alejos, R. Martínez, Romeu, J. D. Martí, Antón, D. González, Quinart, A., Martí, A. Torres, Llaurado-Serra, M., Lobo-Civico, A., Ventura-Rosado, A., Piñol-Tena, A., Pi-Guerrero, M., Paños-Espinosa, C., Peralvo-Bernat, M., Marine-Vidal, J., Gonzalez-Engroba, R., Montesinos-Cerro, N., Treso-Geira, M., Valeiras-Valero, A., Martinez-Reyes, L., Sandiumenge, A., Jimenez-Herrera, M. F., Helyar, S., Riozzi, P., Noon, A., Hallows, G., Cotton, H., Keep, J., Hopkins, P. A., Taggu, A., Renuka, S., Sampath, S., Rood, P. J. T., Frenzel, T., Verhage, R., Bonn, M., Pickkers, P., van der Hoeven, J. G., van den Boogaard, M., Corradi, F., Melnyk, L., Moggia, F., Pienovi, R., Adriano, G., Brusasco, C., Mariotti, L., Lattuada, M., Bloomer, M. J., Coombs, M., Ranse, K., Endacott, R., Maertens, B., Blot, K., Blot, S., Amerongen, M. P. van Nieuw, van der Heiden, E. S., Twisk, J. W. R., Girbes, A. R. J., Spijkstra, J. J., Riozzi, P., Helyar, S., Cotton, H., Hallows, G., Noon, A., Bell, C., Peters, K., Feehan, A., Keep, J., Hopkins, P. A., Churchill, K., Hawkins, K., Brook, R., Paver, N., Endacott, R., Maistry, N., van Wijk, A., Rouw, N., van Galen, T., Evelein-Brugman, S., Taggu, A., Krishna, B., Sampath, S., Putzu, A., Fang, M., Berto, M. Boscolo, Belletti, A., Cassina, T., Cabrini, L., Mistry, M., Alhamdi, Y., Welters, I., Abrams, S. T., Toh, C. H., Han, H. S., Gil, E. M., Lee, D. S., Park, C. M., Winder-Rhodes, S., Lotay, R., Doyle, J., Ke, M. W., Huang, W. C., Chiang, C. H., Hung, W. T., Cheng, C. C., Lin, K. C., Lin, S. C., Chiou, K. R., Wann, S. R., Shu, C. W., Kang, P. L., Mar, G. Y., Liu, C. P., Dubó, S., Aquevedo, A., Jibaja, M., Berrutti, D., Labra, C., Lagos, R., García, M. F., Ramirez, V., Tobar, M., Picoita, F., Peláez, C., Carpio, D., Alegría, L., Hidalgo, C., Godoy, K., Bakker, J., Hernández, G., Sadamoto, Y., Katabami, K., Wada, T., Ono, Y., Maekawa, K., Hayakawa, M., Sawamura, A., Gando, S., Marin-Mateos, H., Perez-Vela, J. L., Garcia-Gigorro, R., Peiretti, M. A. Corres, Lopez-Gude, M. J., Chacon-Alves, S., Renes-Carreño, E., Montejo-González, J. C., Parlevliet, K. L., Touw, H. R. W., Beerepoot, M., Boer, C., Elbers, P. W. G., Tuinman, P. R., Abdelmonem, S. A., Helmy, T. A., El Sayed, I., Ghazal, S., Akhlagh, S. H., Masjedi, M., Hozhabri, K., Kamali, E., Zýková, I., Paldusová, B., Sedlák, P., Morman, D., Youn, A. M., Ohta, Y., Sakuma, M., Bates, D., Morimoto, T., Su, P. L., Chang, W. Y., Lin, W. C., Chen, C. W., Facchin, F., Zarantonello, F., Panciera, G., De Cassai, A., Venrdramin, A., Ballin, A., Tonetti, T., Persona, P., Ori, C., Del Sorbo, L., Rossi, S., Vergani, G., Cressoni, M., Chiumello, D., Chiurazzi, C., Brioni, M., Algieri, I., Tonetti, T., Guanziroli, M., Colombo, A., Tomic, I., Colombo, A., Crimella, F., Carlesso, E., Gasparovic, V., Gattinoni, L., Neto, A. Serpa, Schmidt, M., Pham, T., Combes, A., de Abreu, M. Gama, Pelosi, P., Schultz, M. J., Katira, B. H., Engelberts, D., Giesinger, R. E., Ackerley, C., Yoshida, T., Zabini, D., Otulakowski, G., Post, M., Kuebler, W. M., McNamara, P. J., Kavanagh, B. P., Pirracchio, R., Rigon, M. Resche, Carone, M., Chevret, S., Annane, D., Eladawy, S., El-Hamamsy, M., Bazan, N., Elgendy, M., De Pascale, G., Vallecoccia, M. S., Cutuli, S. L., Di Gravio, V., Pennisi, M. A., Conti, G., Antonelli, M., Andreis, D. T., Khaliq, W., Singer, M., Hartmann, J., Harm, S., Carmona, S. Alcantara, Almudevar, P. Matia, Abellán, A. Naharro, Ramos, J. Veganzones, Pérez, L. Pérez, Valbuena, B. Lobo, Sanz, N. Martínez, Simón, I. Fernández, Arrigo, M., Feliot, E., Deye, N., Cariou, A., Guidet, B., Jaber, S., Leone, M., Resche-Rigon, M., Baron, A. Vieillard, Legrand, M., Gayat, E., Mebazaa, A., Balik, M., Kolnikova, I., Maly, M., Waldauf, P., Tavazzi, G., Kristof, J., Herpain, A., Su, F., Post, E., Taccone, F., Vincent, J. L., Creteur, J., Lee, C., Hatib, F., Jian, Z., Buddi, S., Cannesson, M., Fileković, S., Turel, M., Knafelj, R., Gorjup, V., Stanić, R., Gradišek, P., Cerović, O., Mirković, T., Noč, M., Tirkkonen, J., Hellevuo, H., Olkkola, K. T., Hoppu, S., Lin, K. C., Hung, W. T., Chiang, C. C., Huang, W. C., Juan, W. C., Lin, S. C., Cheng, C. C., Lin, P. H., Fong, K. Y., Hou, D. S., Kang, P. L., Wann, S. R., Chen, Y. S., Mar, G. Y., Liu, C. P., Paul, M., Bougouin, W., Geri, G., Dumas, F., Champigneulle, B., Legriel, S., Charpentier, J., Mira, J. P., Sandroni, C., Cariou, A., Zimmerman, J., Sullivan, E., Noursadeghi, M., Fox, B., Sampson, D., McHugh, L., Yager, T., Cermelli, S., Seldon, T., Bhide, S., Brandon, R. A., Brandon, R. B., Zwaag, J., Beunders, R., Pickkers, P., Kox, M., Gul, F., Arslantas, M. K., Genc, D., Zibandah, N., Topcu, L., Akkoc, T., Cinel, I., Greco, E., Lauretta, M. P., Andreis, D. T., Singer, M., Garcia, I. Palacios, Cordero, M., Martin, A. Diaz, Pallás, T. Aldabó, Montero, J. Garnacho, Rey, J. Revuelto, Malo, L. Roman, Montoya, A. A. Tanaka, Martinez, A. D. C. Amador, Ayala, L. Y. Delgado, Zepeda, E. Monares, Granillo, J. Franco, Sanchez, J. Aguirre, Alejo, G. Camarena, Cabrera, A. Rugerio, Montenegro, A. Pedraza, Pham, T., Beduneau, G., Schortgen, F., Piquilloud, L., Zogheib, E., Jonas, M., Grelon, F., Runge, I., Terzi, N., Grangé, S., Barberet, G., Guitard, P. G., Frat, J. P., Constan, A., Chrétien, J. M., Mancebo, J., Mercat, A., Richard, J. C. M., Brochard, L., Soilemezi, E., Koco, E., Savvidou, S., Nouris, C., Matamis, D., Di Mussi, R., Spadaro, S., Volta, C. A., Mariani, M., Colaprico, A., Antonio, C., Bruno, F., Grasso, S., Rodriguez, A., Martín-Loeches, I., Díaz, E., Masclans, J. R., Gordo, F., Solé-Violán, J., Bodí, M., Avilés-Jurado, F. X., Trefler, S., Magret, M., Reyes, L. F., Marín-Corral, J., Yebenes, J. C., Esteban, A., Anzueto, A., Aliberti, S., Restrepo, M. I., Larsson, J. Skytte, Redfors, B., Ricksten, S. 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Vieira, Kirca, H., Cakin, O., Unal, M., Mutlu, H., Ramazanoglu, A., Cengiz, M., Nicolini, E. A., Pelisson, F. G. F., Nunes, R. S., da Silva, S. L., Carreira, M. M., Bellissimo-Rodrigues, F., Ferez, M. A., Basile-Filho, A., Chao, H. C., Chen, C. M., Chen, L., Hravnak, M., Clermont, G., Pinsky, M., Dubrawski, A., Varas, J. Luján, Montero, R. Molina, Sánchez-Elvira, L. Alcázar, Díaz, P. Villa, Delgado, C. Pintado, Ruiz, B. Llorente, Guerrero, A. Pardo, Galache, J. A. Cambronero, Sherif, H., Hassanin, H., El Hossainy, R., Samy, W., Ly, H., David, H., Burtin, P., Charpentier, C., Barral, M., Courant, P., Fournel, E., Gaide-Chevronnay, L., Durand, M., Albaladejo, P., Payen, J. F., Chavanon, O., Ortiz, A. Blandino, Pozzebon, S., Lheureux, O., Brasseur, A., Vincent, J. L., Creteur, J., Taccone, F. S., Fumagalli, F., Scala, S., Affatato, R., De Maglie, M., Zani, D., Novelli, D., Marra, C., Luciani, A., De Zani, D., Luini, M., Letizia, T., Pravettoni, D., Staszewsky, L., Masson, S., Belloli, A., Di Giancamillo, M., Scanziani, E., Latini, R., Ristagno, G., Kye, Y. C., Suh, G. J., Kwon, W. Y., Kim, K. S., Yu, K. M., Babini, G., Ristagno, G., Grassi, L., Fumagalli, F., Bendel, S., De Maglie, M., Affatato, R., Masson, S., Latini, R., Scanziani, E., Reinikainen, M., Skrifvars, M., Kappler, F., Blobner, M., Schaller, S. J., Roasio, A., Costanzo, E., Cardellino, S., Iesu, E., Cavicchi, F. Zama, Fontana, V., Nobile, L., Vincent, J. L., Creteur, J., Taccone, F. S., Park, M., You, K. M., Suh, G. J., Kwon, W. Y., Ko, S. B., Kim, K. S., Xini, A., Marca, L., Lheureux, O., Brasseur, A., Vincent, J. L., Creteur, J., Taccone, F. S., Beane, A., Thilakasiri, M. C. K. T., De Silva, A. P., Stephens, T., Sigera, C. S., Athapattu, P., Jayasinghe, S., Padeniya, A., Haniffa, R., Santiago, A. Iglesias, Sáez, V. Chica, Ruiz-Ruano, R. de la Chica, González, A. Sánchez, Kunze-Szikszay, N., Wand, S., Klapsing, P., Wetz, A., Heyne, T., Schwerdtfeger, K., Troeltzsch, M., Bauer, M., Quintel, M., Moerer, O., Cook, D. J., Rutherford, W. B., Scales, D. C., Adhikari, N. K., Cuthbertson, B. H., Suzuki, T., Takei, T., Fushimi, K., Iwamoto, M., Nakagawa, S., Mendsaikhan, N., Begzjav, T., Lundeg, G., Dünser, M. W., Romero, D. González, Cabrera, J. L. Santana, Santana, J. D. Martín, Padilla, Y. Santana, Pérez, H. Rodríguez, Torrent, R. Lorenzo, Kleinpell, R., Chouris, I., Radu, V., Stougianni, M., Lavrentieva, A., Lagonidis, D., Price, R. D. T., Day, A., Arora, N., Henderson, M. A., Hickey, S., Costa, M. I. Almeida, Carvalho, J. P., Gomes, A. A., Mergulhão, P. J., Chan, K. K. C., Shum, H. P., Yan, W. W., Maghsoudi, B., Tabei, S. H., Masjedi, M., Sabetian, G., Tabatabaei, H. R., Akbarzadeh, A., Saigal, S., Pakhare, A., Joshi, R., Pattnaik, S. K., Ray, B., Rousseau, A. F., Michel, L., Bawin, M., Cavalier, E., Reginster, J. Y., Damas, P., Bruyere, O., Zhou, J. C., Cauwenberghs, H., De Backer, A., Neels, H., Deblier, I., Berghmans, J., Himpe, D., Barea-Mendoza, J. A., Portillo, I. Prieto, Fernández, M. Valiente, Gigorro, R. Garcia, Vela, J. L. Perez, Mateos, H. Marín, Alves, S. Chacón, Varas, G. Morales, Rodriguez-Biendicho, A., Carreño, E. Renes, González, J. C. Montejo, Yang, J. S., Chiang, C. H., Hung, W. T., Huang, W. C., Cheng, C. C., Lin, K. C., Lin, S. C., Chiou, K. R., Wann, S. R., Lin, K. L., Kang, P. L., Mar, G. Y., Liu, C. P., Zhou, J. C., Choi, Y. J., Yoon, S. Z., Gordillo-Brenes, A., Fernandez-Zamora, M. D., Perez-Borrero, L., Arias-Verdu, M. D., Aguilar-Alonso, E., Herruzo-Aviles, A., Garcia-Delgado, M., Hinojosa-Perez, R., Curiel-Balsera, E., Rivera-Fernandez, R., Lesmes, S. P. Gómez, Rosario, L. E. De la Cruz, Hernández, A. Ansotegui, Herrera, A. N. García, Sanz, E. Regidor, Sánchez, M. J. Gómez, Hualde, J. Barado, Pascual, O. Agudo, León, J. P. Tirapu, Irazabal, J. M. Guergue, Pérez, A. González, Fernández, P. Alvarez, Amor, L. Lopéz, Albaiceta, G. Muñiz, Lesmes, S. P. Gómez, Rosario, L. E. De la Cruz, Hernández, A. Ansotegui, Sanz, E. Regidor, Sánchez, M. J. Gómez, Calvo, S. Aldunate, Herrera, A. N. García, Hualde, J. Barado, Pascual, O. Agudo, León, J. P. Tirapu, Corona, A., Ruffini, C., Spazzadeschi, A., Marrazzo, F., Gandola, A., Sciurti, R., Savi, C., Catena, E., Ke, M. W., Cheng, C. C., Huang, W. C., Chiang, C. H., Hung, W. T., Lin, K. C., Lin, S. C., Wann, S. R., Chiou, K. R., Tseng, C. J., Kang, P. L., Mar, G. Y., Liu, C. P., Bertini, P., De Sanctis, F., Guarracino, F., Bertini, P., Baldassarri, R., Guarracino, F., Buitinck, S. H., van der Voort, P. H. J., Oto, J., Nakataki, E., Tsunano, Y., Izawa, M., Tane, N., Onodera, M., Nishimura, M., Ghosh, S., Gupta, A., De Gasperi, A., Mazza, E., Limuti, R., Prosperi, M., Bissenova, N., Yergaliyeva, A., Talan, L., Yılmaz, G., Güven, G., Yoruk, F., Altıntas, N. D., Mukherjee, D. N., Agarwal, L. K., Mandal, K., Palomar, M., Balsera, B., Vallverdu, M., Martinez, M., Garcia, M., Castellana, D., Lopez, R., Barcenilla, F., Kaminsky, G. E., Carreño, R., Escribá, A., Fuentes, M., Gálvez, V., Del Olmo, R., Nieto, B., Vaquerizo, C., Alvarez, J., De la Torre, M. A., Torres, E., Bogossian, E., Nouer, S. Aranha, Salgado, D. Ribeiro, Brugger, S. Carvalho, Jiménez, G. Jiménez, Torner, M. Miralbés, Vidal, M. Vallverdú, Garrido, B. Balsera, Casals, X. Nuvials, Gaite, F. Barcenilla, Cabello, J. Trujillano, Martínez, M. Palomar, Doganci, M., Izdes, S., Besevli, S. Guzeldag, Alkan, A., Kayaaslan, B., Ramírez, C. Sánchez, Balcázar, L. Caipe, Santana, M. Cabrera, Viera, M. A. Hernández, Escalada, S. Hípola, Vázquez, C. F. Lübbe, Penichet, S. M. Marrero, Campelo, F. Artiles, López, M. A. De La Cal, Santana, P. Saavedra, Santana, S. Ruíz, Repessé, X., Artiguenave, M., Paktoris-Papine, S., Espinasse, F., Dinh, A., El Sayed, F., Charron, C., Géri, G., Vieillard-Baron, A., Marmanidou, K., Oikonomou, M., Nouris, C., Dimitroulakis, K., Soilemezi, E., Matamis, D., Ferré, A., Guillot, M., Teboul, J. L., Lichtenstein, D., Mézière, G., Richard, C., Monnet, X., Pham, T., Beduneau, G., Schortgen, F., Piquilloud, L., Zogheib, E., Jonas, M., Grelon, F., Runge, I., Terzi, N., Grangé, S., Barberet, G., Guitard, P. G., Frat, J. P., Constan, A., Chrétien, J. M., Mancebo, J., Mercat, A., Richard, J. C. M., Brochard, L., Prīdāne, S., Sabeļņikovs, O., Mojoli, F., Orlando, A., Bianchi, I., Torriglia, F., Bianzina, S., Pozzi, M., Iotti, G. A., Braschi, A., Beduneau, G., Pham, T., Schortgen, F., Piquilloud, L., Zogheib, E., Jonas, M., Grelon, F., Runge, I., Terzi, N., Grangé, S., Barberet, G., Guitard, P. G., Frat, J. P., Constan, A., Chrétien, J. M., Mancebo, J., Mercat, A., Richard, J. C. M., Brochard, L., Kondili, E., Psarologakis, C., Kokkini, S., Amargianitakis, V., Babalis, D., Chytas, A., Chouvarda, I., Vaporidi, K., Georgopoulos, D., Trapp, O., Kalenka, A., Mojoli, F., Orlando, A., Bianchi, I., Torriglia, F., Bianzina, S., Pozzi, M., Iotti, G. A., Braschi, A., Lozano, J. A. Benítez, Sánchez, P. Carmona, Francioni, J. E. Barrueco, Ferrón, F. Ruiz, Simón, J. M. Serrano, Spadaro, S., Karbing, D. S., Gioia, A., Moro, F., Corte, F. Dalla, Mauri, T., Volta, C. A., Rees, S. E., Petrova, M. V., Mohan, R., Butrov, A. V., Beeharry, S. D., Vatsik, M. V., Sakieva, F. I., Gobert, F., Yonis, H., Tapponnier, R., Fernandez, R., Labaune, M. A., Burle, J. F., Barbier, J., Vincent, B., Cleyet, M., Richard, J. C., Guérin, C., Shinotsuka, C. Righy, Creteur, J., Taccone, F. S., Törnblom, S., Nisula, S., Vaara, S., Poukkanen, M., Andersson, S., Pettilä, V., Pesonen, E., Xie, Z., Liao, X., Kang, Y., Zhang, J., Kubota, K., Egi, M., Mizobuchi, S., Hegazy, S., El-Keraie, A., El Sayed, E., El Hamid, M. Abd, Rodrigues, N. J., Pereira, M., Godinho, I., Gameiro, J., Neves, M., Gouveia, J., e Silva, Z. Costa, Lopes, J. A., Mckinlay, J., Kostalas, M., Kooner, G., Dudas, G., Horton, A., Kerr, C., Karanjia, N., Creagh-Brown, B., Forni, L., Yamazaki, A., Ganuza, M. Sanz, Molina, J. A. Martinez, Martinez, F. Hidalgo, Freile, M. T. Chiquito, Fernandez, N. Garcia, Travieso, P. Medrano, Bandert, A., Frithiof, R., Lipcsey, M., Smekal, D., Schlaepfer, P., Durovray, J. D., Plouhinec, V., Chiappa, C., Bellomo, R., Schneider, A. G., Mitchell, S., Durrant, J., Street, H., Dunthorne, E., Shears, J., Caballero, C. Hernandez, Hutchison, R., Schwarze, S., Ghabina, S., Thompson, E., Prowle, J. R., Kirwan, C. J., Gonzalez, C. A., Pinto, J. L., Orozco, V., Patiño, J. A., Garcia, P. K., Contreras, K. M., Rodriguez, P., Echeverri, J. E., GETGAG Working Group, JSEPTIC (Japanese Society of Education for Physicians and Trainees in Intensive Care) Clinical Trial Group, CAPCRI Study, for the ReVA Research Network and the PROVE Network Investigators, from the FROG ICU Investigators, The WIND study group, Plug Working Group, GETGAG/SEMICYUC, AKI Research Group, St George’s University of London, IPREA Study Group, FINNRESUSCI Study Group, PICS- HCPA: Programa Intrahospitalar de Combate à Sepse do Hospital de Clínicas de Porto Alegre, ENVIN-HELICS Study Group, ARIAM registry of adult cardiac surgery, The Rapid Diagnosis of Infections in the Critically Ill Team, Tokyo Womens Medical University, PLUG working group, PLUG Working Group, On behalf of Okayama Research Investigation Organizing Network (ORION)investigators, PS-ICU Group, Japan Septic Disseminated Intravascular Coagulation (JSEPTIC DIC) study group, Student Research Committee - Shiraz University of Medical Sciences, ARIAM-ANDALUCIA, The WIND study group, PLUG Working Group, The WIND study group, PLUG Working Group, and Plug working group
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- 2016
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9. Perfluorooctanoic acid affects the activity of the hepatocyte nuclear factor 4 alpha (HNF4α)
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Scharmach, E., Buhrke, T., Lichtenstein, D., and Lampen, A.
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- 2012
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10. A call to safeguard sexual and reproductive health information and services during Ebola outbreaks
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Tran, NT, Lichtenstein, D, Black, B, Rosmini, A, Schulte-Hillen, C, Tran, NT, Lichtenstein, D, Black, B, Rosmini, A, and Schulte-Hillen, C
- Abstract
The recent Ebola virus disease (EVD) outbreaks in 2021 exemplify how sexual and reproductive health services are too often considered unessential during health emergencies. Bleeding for reasons other than EVD, such as pregnancy complications or rape, can be construed as EVD symptoms, reinforcing fear and stigmatisation, and delaying timely access to adequate care. In this commentary, we urgently call on all humanitarian actors to integrate the Minimum Initial Services Package for Sexual and Reproductive Health in Crisis Situations into current and future EVD preparedness and response efforts.
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- 2021
11. Échographie pulmonaire en réanimation et aux urgences
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Lichtenstein, D.
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- 2008
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12. INGN 007, an oncolytic adenovirus vector, replicates in Syrian hamsters but not mice: comparison of biodistribution studies
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Ying, B, Toth, K, Spencer, J F, Meyer, J, Tollefson, A E, Patra, D, Dhar, D, Shashkova, E V, Kuppuswamy, M, Doronin, K, Thomas, M A, Zumstein, L A, Wold, W S M, and Lichtenstein, D L
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- 2009
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13. An acute toxicology study with INGN 007, an oncolytic adenovirus vector, in mice and permissive Syrian hamsters; comparisons with wild-type Ad5 and a replication-defective adenovirus vector
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Lichtenstein, D L, Spencer, J F, Doronin, K, Patra, D, Meyer, J M, Shashkova, E V, Kuppuswamy, M, Dhar, D, Thomas, M A, Tollefson, A E, Zumstein, L A, Wold, W S M, and Toth, K
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- 2009
- Full Text
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14. Mixture effects on toxicologically relevant liver proteins after pesticide treatment in hepaRG cells
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Schmidt, F., Steinhilber, A., Mentz, Almut, Kalinowski, Jörn, Lichtenstein, D., Braeuning, A., Joos, T., and Poetz, O.
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- 2020
15. Recommendations for core critical care ultrasound competencies as a part of specialist training in multidisciplinary intensive care: a framework proposed by the European Society of Intensive Care Medicine (ESICM)
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Wong A, Galarza L, Forni L, De Backer D, Slama M, Cholley B, Mayo P, McLean A, Vieillard-Baron A, Lichtenstein D, Volpicelli G, Arntfield R, Martin-Loeches I, Istrate GM, Duška F, and ESICM Critical Care Ultrasound Group
- Subjects
Core critical care ultrasound ,Specialist training ,Competencies ,Education in intensive care - Abstract
Critical care ultrasound (CCUS) is an essential component of intensive care practice. Although existing international guidelines have focused on training principles and determining competency in CCUS, few countries have managed to operationalize this guidance into an accessible, well-structured programme for clinicians training in multidisciplinary intensive care. We seek to update and reaffirm appropriate CCUS scope so that it may be integrated into the international Competency-based Training in Intensive Care Medicine. The resulting recommendations offer the most contemporary and evolved set of core CCUS competencies for an intensive care clinician yet described. Importantly, we discuss the rationale for inclusion but also exclusion of competencies listed. Background/aim Critical care ultrasound (CCUS) is an essential component of intensive care practice. The purpose of this consensus document is to determine those CCUS competencies that should be a mandatory part of training in multidisciplinary intensive care. Methods A three-round Delphi method followed by face-to-face meeting among 32 CCUS experts nominated by the European Society of Intensive Care Medicine. Agreement of at least 90% of experts was needed in order to enlist a competency as mandatory. Results The final list of competencies includes 15 echocardiographic, 5 thoracic, 4 abdominal, deep vein thrombosis diagnosis and central venous access aid. Conclusion The resulting recommendations offer the most contemporary and evolved set of core CCUS competencies for an intensive care clinician yet described.
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- 2020
16. The internal jugular veins are asymmetric. Usefulness of ultrasound before catheterization
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Lichtenstein, D., Saïfi, R., Augarde, R., Prin, S., Schmitt, J.M., Page, B., Pipien, I., and Jardin, F.
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- 2001
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17. Lethal autosomal recessive epidermolysis bullosa simplex with bowel atresia due to a novel plectin mutation: PA11
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Lichtenstein, D. A., Browne, F., Daly, B. M., Liu, L., McGrath, J. A., and Moss, C.
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- 2012
18. Feasibility and safety of ultrasound-aided thoracentesis in mechanically ventilated patients
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Lichtenstein, D., Hulot, J.-S., Rabiller, A., Tostivint, I., and Mezière, G.
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- 1999
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19. The comet-tail artifact: an ultrasound sign ruling out pneumothorax
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Lichtenstein, D., Mezière, G., Biderman, P., and Gepner, A.
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- 1999
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20. A lung ultrasound sign allowing bedside distinction between pulmonary edema and COPD: the comet-tail artifact
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Lichtenstein, D. and Mezière, G.
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- 1998
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21. The “sinusogram”, a real-time ultrasound sign of maxillary sinusitis
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Lichtenstein, D., Biderman, P., Mezière, G., and Gepner, A.
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- 1998
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22. Deliverable 4.3 - Draft scientific article describing the in vivo studies
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Schreiber, E., Garcia, T., González, N., Esplugas, R., Torrente, M., Gómez, M., Domingo, J.L., Menegola, E., Di Renzo, F., Battistoni, M., Metruccio, F., Fustinoni, S., Moretto, A., Kyriakopoulou, K., Spyropoulou, A., Mpatakis, P., Machera, K., Waizenegger, J., Lichtenstein, D., Luckert, C., Peijnenburg, A., Stoopen, G., Braeuning, A., and Lampen, A.
- Abstract
This deliverable provides information on the study design and dosing of the EuroMix in vivo toxicitystudies as well as descriptions of the used methods for the parameters tested and evaluated so far.Furthermore, the results of the measured parameters are described, followed by a short conclusion and outlook.
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- 2019
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23. Deliverable D3.5 Results of the in vitro testing of mixtures regarding liver toxicity and craniofacial malformation
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Luckert, C., Lichtenstein, D., Braeuning, A., de Sousa, G., Durinck, S., Katsanou, E. S., Konstantinidou, P., Machera, K., Milani, E. S., Peijnenburg, A., Rahmani, R., Rajkovic, A., Rijkers, D., Spyropoulou, A., Stamou, M., Stoopen, G., Sturla, S. J., Wollscheid, B., Zucchini‐Pascal, N., Lampen, A., Moretto, A., di Renzo, F., Kyriakopoulou, K., Metruccio, F., Menegola, E., and van der Ven, L.
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AOP, craniofacial malformation, mixtures, in vitro, RPFs - Abstract
This deliverable consists of two parts and provides an instruction on the EuroMix testing strategy for testing compounds grouped based on their Mode of action (MoA) and their mixtures regarding the liver specific endpoint steatosis (Part 1) and regarding the craniofacial malformation specific endpoint following the same approach (Part 2).
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- 2019
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24. A targeted transcriptomic and proteomic approach to assess hepatotoxic mixture effects in vitro
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Braeuning, A., Lichtenstein, D., Mentz, Almut, Kalinowski, Jörn, Schmidt, F., Poetz, O., and Lampen, A.
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- 2019
25. LOSS OF BCL-2 IMMUNOREACTIVITY IN POROKERATOSES.
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Lichtenstein, D A, Tam, S, and Kamino, H
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- 1998
26. Management of occluded biliary Wallstents
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Tham, T C K, Carr-Locke, D L, Vandervoort, J, Wong, R C K, Lichtenstein, D R, Van Dam, J, Ruymann, F, Chow, S, Bosco, J J, Qaseem, T, Howell, D, Pleskow, D, Vannerman, W, and Libby, E D
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- 1998
27. Diagnosis of internal jugular vein thrombosis
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Lichtenstein, D., Jardin, F., and Cohen, Y.
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- 1997
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28. Intensive use of general ultrasound in the intensive care unit: Prospective study of 150 consecutive patients
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Lichtenstein, D. and Axler, O.
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- 1993
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29. Analysis of toxicologically relevant biomarkers in pesticide-treated HepaRG cells by MS-based immunoassays
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Schmidt, F.F., primary, Steinhilber, A.E., additional, Hammer, H.S., additional, Mentz, A., additional, Kalinowski, J., additional, Lichtenstein, D., additional, Braeuning, A., additional, Marx-Stoelting, P., additional, Lampen, A., additional, Joos, T., additional, and Pötz, O., additional
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- 2018
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30. Aftereffects of Auger Ionization Following Electron Capture in Cobalt Complexes
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Nath, A., Klein, M. P., Kündig, W., Lichtenstein, D., and Gruverman, Irwin J., editor
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- 1970
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31. The time is now – a call to action for gender equality in global health leadership
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Dhatt, R., primary, Thompson, K., additional, Lichtenstein, D., additional, Ronsin, K., additional, and Wilkins, K., additional
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- 2017
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32. The role of women's leadership and gender equity in leadership and health system strengthening
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Dhatt, R., primary, Theobald, S., additional, Buzuzi, S., additional, Ros, B., additional, Vong, S., additional, Muraya, K., additional, Molyneux, S., additional, Hawkins, K., additional, González-Beiras, C., additional, Ronsin, K., additional, Lichtenstein, D., additional, Wilkins, K., additional, Thompson, K., additional, Davis, K., additional, and Jackson, C., additional
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- 2017
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33. Comparison of two different application routes of nanosilver in rats - evidence for nanoparticles after silver ion treatment
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Juling, S., Lichtenstein, D., Selve, S., Oberemm, A., Creutzenberg, Otto, Braeuning, A., Lampen, A., and Publica
- Abstract
The unique properties of silver nanoparticles have a great potential to advance food safety and revolutionize food packaging. Despite these promising applications, there are concerns about the impact of silver nanoparticles on human health. Therefore, the tissue distribution and excretion of coated silver nanoparticles was investigated in rats after single oral administration including a 7-days post treatment observation time. The animals received silver nanoparticles at a dose of 20 mg/kg body weight and an equimolar dose of silver ions by gavage. The silver content was measured in different organs after days 1, 2, 3 and 7. To assess the effect of the intestinal passage on systemic bioavailability, an additional group of rats was intravenously administered with 4 mg/kg body weight silver nanoparticles and another group was treated with an equimolar dose of silver ions. The fate of the silver was compared after 24 h single intravenous administration. An accumulation of silver was observed in different organs. As expected, most of the nanosilver was excreted via feces and minor amounts were detected in intestine and colon. Orally administered ionic silver was detected in feces and additionally in the urine. Remarkably, also after intravenous injection of nanosilver, silver was found in feces, which suggests biliary excretion of silver nanoparticles. In addition to this, the formation of small Ag2S nanoparticles was observed after ionic administration. It is concluded that the oral resorption of nanosilver results in an accumulation of silver in different organs and feces. Results obtained after intravenous application suggest a biliary excretion. Formation of small Ag2S nanoparticles can be detected after ionic silver application.
- Published
- 2015
34. French Intensive Care Society, International congress - Réanimation 2016
- Author
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Elkhawand, C, Vermeesh, F, Vermeesh, F., and CITERIO, GIUSEPPE
- Abstract
Determinants of outcome in critically ill patients with hematological malignancy and central neurological failure: data from the TRIAL OH study
- Published
- 2016
35. Feasibility of ultrasound in the helicopter
- Author
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Lichtenstein, D. and Courret, J.-P.
- Published
- 1998
- Full Text
- View/download PDF
36. Relation of protein corona and proteomic changes
- Author
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Juling, S., primary, Niedzwiecka, A., additional, Böhmert, L., additional, Lichtenstein, D., additional, Sieg, H., additional, Schümann, M., additional, Selve, S., additional, Braeuning, A., additional, Krause, E., additional, and Lampen, A., additional
- Published
- 2016
- Full Text
- View/download PDF
37. Core or coating material? What dictates the uptake and translocation of nanoparticles in vitro?
- Author
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Lichtenstein, D., primary, Böhmert, L., additional, Meyer, T., additional, Sieg, H., additional, Thünemann, A.F., additional, Estrela Lopis, I., additional, Braeuning, A., additional, and Lampen, A., additional
- Published
- 2016
- Full Text
- View/download PDF
38. Protein corona analysis indicates clathrin-mediated endocytosis of carboxydextran-coated nanoparticles in HepG2 cells
- Author
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Juling, S., primary, David, J., additional, Lalkowski, G., additional, Lichtenstein, D., additional, Böhmert, L., additional, Rozycki, C., additional, Braeuning, A., additional, and Lampen, A., additional
- Published
- 2016
- Full Text
- View/download PDF
39. Evidence for particle-specific and coating-related uptake of silver nanoparticles
- Author
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Lichtenstein, D., primary, Meyer, T., additional, Böhmert, L., additional, Sieg, H., additional, Juling, S., additional, Thünemann, A.F., additional, Estrela Lopis, I., additional, Braeuning, A., additional, and Lampen, A., additional
- Published
- 2016
- Full Text
- View/download PDF
40. Systemic tissue distribution of silver nanoparticles in vivo
- Author
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Juling, S., primary, Bachler, G., additional, Lichtenstein, D., additional, Böhmert, L., additional, Niedzwiecka, A., additional, Sieg, H., additional, Selve, S., additional, Braeuning, A., additional, and Lampen, A., additional
- Published
- 2016
- Full Text
- View/download PDF
41. Effects of Al-, Ti- and Zn-containing nanomaterials on cell lines in vitro
- Author
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Sieg, H., primary, Lehmann, C., additional, Kaestner, C., additional, Krause, B., additional, Burel, A., additional, Chevance, S., additional, Böhmert, L., additional, Lichtenstein, D., additional, Tentschert, J., additional, Breauning, A., additional, Laux, P., additional, Thuenemann, A., additional, Estrela Lopis, I., additional, Fessard, V., additional, Luch, A., additional, and Lampen, A., additional
- Published
- 2016
- Full Text
- View/download PDF
42. Some extremal problems arising from discrete control processes
- Author
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Lichtenstein, D., Linial, N., and Saks, M.
- Published
- 1989
- Full Text
- View/download PDF
43. The influence of food components during artificial digestion on silver nanoparticles and the impact on their cytotoxicity and uptake in Caco-2 cells
- Author
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Lichtenstein, D., primary, Ebmeyer, J., additional, Knappe, P., additional, Juling, S., additional, Böhmert, L., additional, Selve, S., additional, Niemann, B., additional, Braeuning, A., additional, Thünemann, A., additional, and Lampen, A., additional
- Published
- 2015
- Full Text
- View/download PDF
44. Silver nanoparticle, stabilizer and ion influence on the proteome of Caco-2 cells
- Author
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Juling, S., primary, Lichtenstein, D., additional, Böhmert, L., additional, Niedzwiecka, A., additional, Selve, S., additional, Schümann, M., additional, Thünemann, A., additional, Braeuning, A., additional, Krause, E., additional, and Lampen, A., additional
- Published
- 2015
- Full Text
- View/download PDF
45. Fournier's gangrene complicating perianal abscess: Report of two cases
- Author
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Lichtenstein, D., Stavorovsky, M., and Irge, D.
- Published
- 1978
- Full Text
- View/download PDF
46. CARD9 Deficiency and Spontaneous Central Nervous System Candidiasis: Complete Clinical Remission With GM-CSF Therapy
- Author
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Gavino, C., primary, Cotter, A., additional, Lichtenstein, D., additional, Lejtenyi, D., additional, Fortin, C., additional, Legault, C., additional, Alirezaie, N., additional, Majewski, J., additional, Sheppard, D. C., additional, Behr, M. A., additional, Foulkes, W. D., additional, and Vinh, D. C., additional
- Published
- 2014
- Full Text
- View/download PDF
47. Cost effectiveness of screening for and eradication of Helicobacter pylori in young patients with dyspepsia. Comparison groups were not clear in study
- Author
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Tham, T. C. and Lichtenstein, D. R.
- Subjects
Adult ,Peptic Ulcer ,Letter ,Helicobacter pylori ,Cost-Benefit Analysis ,Decision Trees ,Middle Aged ,Sensitivity and Specificity ,State Medicine ,United Kingdom ,Helicobacter Infections ,Treatment Outcome ,Recurrence ,Costs and Cost Analysis ,Humans ,Mass Screening ,Dyspepsia - Abstract
To assess the cost effectiveness of screening for and eradicating Helicobacter pylori in patients under 45 years of age presenting with dyspepsia.A decision analytic model composed of a decision tree to represent the epidemiology of dyspepsia and a Markov process to model the outcomes of treatment.Patients under the age of 45 years presenting to their general practitioner with (peptic type) dyspepsia.Conventional empirical treatment with healing and maintenance doses of cimetidine v eradication treatment solely in patients with confirmed peptic ulcer; and conventional empirical treatment for all dyspeptic patients compared with the use of a serology test to identify patients with H pylori, who then receive endoscopy to investigate the presence of peptic ulcer disease and, when disease is found, are given eradication treatment with a breath test to confirm successful eradication.Expected cumulative costs over a period of 10 years. The proportion of time patients spend without a recurrent ulcer.After receiving eradication treatment, patients with confirmed ulcer spend an average of 99% of their time free from recurrent ulcer disease compared with 95% after treatment with cimetidine. Eradication treatment costs less than that with cimetidine. When the initial cost of identifying appropriate patients to receive eradication treatment is added to the analysis, however, these cost savings take almost eight years to accrue.Enthusiasm for introducing testing for and eradication of H pylori for dyspeptic patients in general practice should be tempered by an awareness that cost savings may take many years to realise.
- Published
- 1996
48. Amyloidosis of the gastrointestinal tract: a 13-year, single-center, referral experience
- Author
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Cowan, A. J., primary, Skinner, M., additional, Seldin, D. C., additional, Berk, J. L., additional, Lichtenstein, D. R., additional, O'Hara, C. J., additional, Doros, G., additional, and Sanchorawala, V., additional
- Published
- 2012
- Full Text
- View/download PDF
49. A randomized trial comparing uncovered and partially covered self- expandable metal stents in the palliation of distal malignant biliary obstruction
- Author
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J., Telford J, additional, L., Carr-Locke D, additional, H., Baron T, additional, M., Poneros J, additional, C., Bounds B, additional, B., Kelsey P, additional, H., Schapiro R, additional, S., Huang C, additional, R., Lichtenstein D, additional, C., Jacobson B, additional, R., Saltzman J, additional, C., Thompson C, additional, G., Forcione D, additional, J., Gostout C, additional, and R., Brugge W, additional
- Published
- 2011
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- View/download PDF
50. Ultrasound performs better than radiographs
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Agricola, E., primary, Arbelot, C., additional, Blaivas, M., additional, Bouhemad, B., additional, Copetti, R., additional, Dean, A., additional, Dulchavsky, S., additional, Elbarbary, M., additional, Gargani, L., additional, Hoppmann, R., additional, Kirkpatrick, A. W., additional, Lichtenstein, D., additional, Liteplo, A., additional, Mathis, G., additional, Melniker, L., additional, Neri, L., additional, Noble, V. E., additional, Petrovic, T., additional, Reissig, A., additional, Rouby, J. J., additional, Seibel, A., additional, Soldati, G., additional, Storti, E., additional, Tsung, J. W., additional, Via, G., additional, and Volpicelli, G., additional
- Published
- 2010
- Full Text
- View/download PDF
Catalog
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