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123 results on '"Liberti, Marcello"'

2. Paraurethral Leiomyoma

Author

Perugia, Giacomo, Ciccariello, Mauro, Pirolli, Francesca, Chinazzi, Alessandro, Teodonio, Simone, Borgoni, Giuseppe, Croce, Francesco, and Liberti, Marcello

Published
2012
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4. Analysis of STAT3 post-translational modifications (PTMs) in human prostate cancer with different Gleason Score

Author

Cocchiola, Rossana, primary, Romaniello, Donatella, additional, Grillo, Caterina, additional, Altieri, Fabio, additional, Liberti, Marcello, additional, Magliocca, Fabio Massimo, additional, Chichiarelli, Silvia, additional, Marrocco, Ilaria, additional, Borgoni, Giuseppe, additional, Perugia, Giacomo, additional, and Eufemi, Margherita, additional

Published
2017
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7. Long-term experience with early single mitomycin C instillations in patients with low-risk non-muscle-invasive bladder cancer: prospective, single-centre randomised trial

Author

Cosimo, Nunzio, DE NUNZIO, Cosimo, Carbone, Antonio, Alpi, Giorgio, Cantiani, Andrea, Liberti, Marcello, Tubaro, Andrea, Iori, Francesco, and Albisinni, Simone

Subjects
Male, medicine.medical_specialty, Urology, Mitomycin, law.invention, Randomized controlled trial, law, Risk Factors, mitomycin, follow-up, non-muscle-invasive bladder cancer, transurethral resection, low-risk, Clinical endpoint, Medicine, Humans, Longitudinal Studies, Prospective Studies, Prospective cohort study, Aged, Retrospective Studies, Bladder cancer, Antibiotics, Antineoplastic, business.industry, Mitomycin C, Absolute risk reduction, Retrospective cohort study, Middle Aged, medicine.disease, Combined Modality Therapy, Surgery, Administration, Intravesical, Treatment Outcome, Urinary Bladder Neoplasms, Number needed to treat, Urologic Surgical Procedures, Female, Neoplasm Recurrence, Local, business, Follow-Up Studies
Abstract

To study the benefits of a single, early, intravesical instillation of mitomycin C(MMC) after transurethral bladder resection (TURB) in patients with low-risk non-muscle-invasive bladder cancer (NMIBC). In this prospective randomised single-centre trial, 211 patients with primary and low-risk tumours were enrolled between 2000 and 2009. Patients were randomly allocated to receive MMC intravesically within 24 h of TUR or no further treatment. The primary end point was recurrence rate reduction. A total of 202 patients (97 in the MMC group and 105 in the control group) remained for analysis after exclusions. Median age was 61 years (IQR 42–78), and median follow-up was 90 months (IQR 3–112). No significant differences for patients’ characteristics were observed between the two groups. During the study period, 10% (10/97) of the patients in the MMC group and 43% (46/105) in the control group experienced a recurrence (P = 0.0001). Four patients in the MMC group and 11 (P = 0.008) in the control group experienced an early recurrence (within 2 years). One patient in the control group presented a tumour progression (T2G3). MMC treatment was associated with a 31% absolute risk reduction of recurrence and a 3.26 numbers needed to treat to prevent one recurrence. In this single-centre, long-term follow-up, experience a single, early instillation of MMC after TUR for low-risk NMIBC is associated with a significant reduction in risk of early and late recurrences.

Published
2011

46. La gangrena di Fournier

Author

Liberti, Marcello, Perugia, Giacomo, Gatto, A., Stano, C., and Cerulli, N.

Published
1996

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