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The garment pressure comfort sensation and discrimination were studied in the paper. The garment pressure comfort threshold and difference threshold were defined and calculated according to staircase method of psychophysics. In experiment, 10 subjects were employed in sensory tests and pressure measurements. A novel stretchable compressive belt was developed, which was used to control the pressure applied on separate body parts by its extension and intention, and the subjects judgement and pressure monitor were recorded in times. Finally, the comfort thresholds at nine separate body parts below waistline and difference thresholds at three parts & three varied standard pressure levels were investigated. This study provided proper comfort pressure range to human body for developing compression wear. Practitioner summary: Garment pressure comfort and difference threshold were firstly defined and calculated according to staircase method of psychophysics. The comfort thresholds at nine body parts and difference thresholds at three parts & three varied standard pressure levels were investigated. This study provided proper comfort pressure range to human body for developing compression wear. [ABSTRACT FROM AUTHOR]