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528 results on '"Liao, Xiaobin"'

33. Embryotoxicity of Diafenthiuron to Zebrafish (Danio rerio) After Advanced Oxidation Treatment.

Author

Su, Menglan, Bao, Rongkai, Gao, Bo, Liao, Xiaobin, Xiao, Peng, and Li, Wenhua

Subjects
NON-target organisms, REACTIVE oxygen species, ZEBRA danio, WASTEWATER treatment, ULTRAVIOLET radiation, THIOUREA
Abstract

Diafenthiuron is a novel derivative of thiourea and is highly toxic to non-target organisms, necessitating its efficient removal from wastewater before discharge. This study compared diafenthiuron removal efficiencies at a target concentration of 1 µM using three methods: a 4 mg/L ozone (O3) treatment; an ultraviolet (UV) light treatment, applying UV254 radiation with a fluence of 60 mJ/cm2 for 10 min; and a combined O3/UV treatment utilizing ozone and ultraviolet light. An acute toxicity assessment was conducted using a modeled zebrafish embryo (Danio rerio). The diafenthiuron removal efficiencies were 49.59%, 54.51%, and 68.90% for the UV light, O3, and O3/UV treatments, respectively. The treatments showed additional benefits of exerting no negative impacts on the survival rate, heart rate, or body length of the zebrafish larvae posttreatment. The survival and heart rates at 120 hpf, as well as the body length at 96 and 120 hpf, showed significant differences between the advanced oxidation and 1 μM diafenthiuron treatment groups. However, these parameters remained consistent with those of the control group. The three treatments alleviated the spatiotemporal downregulation of the liver-specific marker fabp10a caused by diafenthiuron exposure. The UV light and O3/UV treatments were efficient at degrading diafenthiuron, causing decreased reactive oxygen species levels and increased pomc and prl expression levels. The O3-treated diafenthiuron and 1 μM diafenthiuron treatments increased the reactive oxygen species levels and decreased the pomc and prl expression levels. The combined O3/UV treatment showed the highest removal efficiency and the least toxicity, making it the most effective method for diafenthiuron degradation. This study provides valuable insights into the treatment of diafenthiuron-laden wastewater. [ABSTRACT FROM AUTHOR]

Published
2024
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34. The Promising Potency of Sodium–Glucose Cotransporter 2 Inhibitors in the Prevention of and as Treatment for Cognitive Impairment Among Type 2 Diabetes Patients.

Author

Zhang, Yibin, Liao, Xiaobin, Xu, Jialu, Yin, Jiaxin, Li, Shan, Li, Mengni, Shi, Xiaoli, Zhang, Shujun, Li, Chunyu, Xu, Weijie, Yu, Xuefeng, and Yang, Yan

Subjects
TYPE 2 diabetes, MILD cognitive impairment, PROXIMAL kidney tubules, ALZHEIMER'S disease, SODIUM-glucose cotransporters, VASCULAR dementia
Abstract

Type 2 diabetes mellitus (T2DM), accounting for the majority of diabetes mellitus prevalence, is associated with an increased risk of cognition decline and deterioration of cognition function in diabetic patients. The sodium–glucose cotransporter 2 (SGLT2), located in the renal proximal tubule, plays a role in urine glucose reabsorption. SGLT2 inhibitors (SGLT2i), have shown potential benefits beyond cardiac and renal improvement in preventing and treating cognitive impairment (CI), including mild cognitive impairment, Alzheimer's disease and vascular dementia in T2DM patients. Studies suggest that SGLT2i may ameliorate diabetic CI through metabolism pathways, inflammation, oxidative stress, neurotrophic factors and AChE inhibition. Clinical trials and meta-analyses have reported significant and insignificant results. Given their vascular effects, SGLT2i may offer unique protection against vascular CI. This review compiles mechanisms and clinical evidence, emphasizing the need for future analysis, evaluation, trials and meta-analyses to verify and recommend optimal SGLT2i selection and dosage for specific patients. [ABSTRACT FROM AUTHOR]

Published
2024
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48. Catalytic ozonation performance and mechanisms of Cu-Co/γ-Al2O3to achieve antibiotics and ammonia simultaneously removal in aquaculture wastewater

Author

Liu, Shupo, He, Zixiang, Liao, Xiaobin, Liu, Xinyue, Gao, Menglan, Zhang, Huayu, Zou, Jing, Zhou, Zhenming, Yuan, Baoling, and Yang, Zhimin

Abstract

Antibiotics and ammonia are generally co-existed in aquaculture tailwater; moreover, ammonia would also be produced from during ozonation, and should be simultaneously removed before discharge or reuse. In this study, catalyst Cu-Co/γ-Al2O3was screened from a variety of metal oxides and applied in catalytic ozonation of three kinds of antibiotics and NH+4-N. Factors that affected their removal, including catalyst dosages, O3concentration, initial pH as well as co-existing ions, were investigated. Moreover, the mechanisms were probed by exploring free radicals’ role as well as intermediates identification; and the characteristics of catalysts before and after use were evaluated using SEM, EDS, XRD, XPS, and BET. Results demonstrated that Cu-Co/γ-Al2O3could significantly stimulate the degradation of the selected antibiotics and NH+4-N during ozonation. The degradation efficiencies of ciprofloxacin (CIP), tetracycline (TC), sulfamethoxazole (SMX) and NH+4-N can reach up to 95.0 %, 100.0 %, 96.2 %, and 75.7 %, respectively. Plenty of oxygen vacancy (Ovs) and sufficient alkaline sites on the surface of catalyst facilitated the adsorption of pollutants. Furthermore, the transformation of metal ions Cu+/Cu2+and Co2+/Co3+enhanced the electron transfer capacity and favored the formation of reactive oxygen species (ROS) during catalytic ozonation reaction, and their roles in catalytic ozonation has also been verified. The radical quenching experiments demonstrated that ·OH was the main contributor for enhancing pollutants removal. The results of Gaussian calculation coincided with those intermediates detected by UPLC-Q-TOF-MS, the pollutants’ removal mechanisms by catalytic ozonation were proposed basing on them. The overall toxicities were compared for ozone only/catalytic ozonation by zebrafish embryo experiment. The results of this study would provide new a feasible way for treating antibiotics and NH+4-N simultaneously in aquaculture wastewater.

Published
2024
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