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4. Supplementary Table 1 from Development of an Fc-Enhanced Anti–B7-H3 Monoclonal Antibody with Potent Antitumor Activity

Author

Loo, Deryk, primary, Alderson, Ralph F., primary, Chen, Francine Z., primary, Huang, Ling, primary, Zhang, Wenjun, primary, Gorlatov, Sergey, primary, Burke, Steve, primary, Ciccarone, Valentina, primary, Li, Hua, primary, Yang, Yinhua, primary, Son, Tom, primary, Chen, Yan, primary, Easton, Ann N., primary, Li, Jonathan C., primary, Rillema, Jill R., primary, Licea, Monica, primary, Fieger, Claudia, primary, Liang, Tony W., primary, Mather, Jennie P., primary, Koenig, Scott, primary, Stewart, Stanford J., primary, Johnson, Syd, primary, Bonvini, Ezio, primary, and Moore, Paul A., primary

Published
2023
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5. Supplementary Figure 3 from Development of an Fc-Enhanced Anti–B7-H3 Monoclonal Antibody with Potent Antitumor Activity

Author

Loo, Deryk, primary, Alderson, Ralph F., primary, Chen, Francine Z., primary, Huang, Ling, primary, Zhang, Wenjun, primary, Gorlatov, Sergey, primary, Burke, Steve, primary, Ciccarone, Valentina, primary, Li, Hua, primary, Yang, Yinhua, primary, Son, Tom, primary, Chen, Yan, primary, Easton, Ann N., primary, Li, Jonathan C., primary, Rillema, Jill R., primary, Licea, Monica, primary, Fieger, Claudia, primary, Liang, Tony W., primary, Mather, Jennie P., primary, Koenig, Scott, primary, Stewart, Stanford J., primary, Johnson, Syd, primary, Bonvini, Ezio, primary, and Moore, Paul A., primary

Published
2023
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6. Supplementary Figure 2 from Development of an Fc-Enhanced Anti–B7-H3 Monoclonal Antibody with Potent Antitumor Activity

Author

Loo, Deryk, primary, Alderson, Ralph F., primary, Chen, Francine Z., primary, Huang, Ling, primary, Zhang, Wenjun, primary, Gorlatov, Sergey, primary, Burke, Steve, primary, Ciccarone, Valentina, primary, Li, Hua, primary, Yang, Yinhua, primary, Son, Tom, primary, Chen, Yan, primary, Easton, Ann N., primary, Li, Jonathan C., primary, Rillema, Jill R., primary, Licea, Monica, primary, Fieger, Claudia, primary, Liang, Tony W., primary, Mather, Jennie P., primary, Koenig, Scott, primary, Stewart, Stanford J., primary, Johnson, Syd, primary, Bonvini, Ezio, primary, and Moore, Paul A., primary

Published
2023
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7. Supplementary Figure Legend from Development of an Fc-Enhanced Anti–B7-H3 Monoclonal Antibody with Potent Antitumor Activity

Author

Loo, Deryk, primary, Alderson, Ralph F., primary, Chen, Francine Z., primary, Huang, Ling, primary, Zhang, Wenjun, primary, Gorlatov, Sergey, primary, Burke, Steve, primary, Ciccarone, Valentina, primary, Li, Hua, primary, Yang, Yinhua, primary, Son, Tom, primary, Chen, Yan, primary, Easton, Ann N., primary, Li, Jonathan C., primary, Rillema, Jill R., primary, Licea, Monica, primary, Fieger, Claudia, primary, Liang, Tony W., primary, Mather, Jennie P., primary, Koenig, Scott, primary, Stewart, Stanford J., primary, Johnson, Syd, primary, Bonvini, Ezio, primary, and Moore, Paul A., primary

Published
2023
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8. Supplementary Table 2 from Development of an Fc-Enhanced Anti–B7-H3 Monoclonal Antibody with Potent Antitumor Activity

Author

Loo, Deryk, primary, Alderson, Ralph F., primary, Chen, Francine Z., primary, Huang, Ling, primary, Zhang, Wenjun, primary, Gorlatov, Sergey, primary, Burke, Steve, primary, Ciccarone, Valentina, primary, Li, Hua, primary, Yang, Yinhua, primary, Son, Tom, primary, Chen, Yan, primary, Easton, Ann N., primary, Li, Jonathan C., primary, Rillema, Jill R., primary, Licea, Monica, primary, Fieger, Claudia, primary, Liang, Tony W., primary, Mather, Jennie P., primary, Koenig, Scott, primary, Stewart, Stanford J., primary, Johnson, Syd, primary, Bonvini, Ezio, primary, and Moore, Paul A., primary

Published
2023
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9. Supplementary Figure 4 from Development of an Fc-Enhanced Anti–B7-H3 Monoclonal Antibody with Potent Antitumor Activity

Author

Loo, Deryk, primary, Alderson, Ralph F., primary, Chen, Francine Z., primary, Huang, Ling, primary, Zhang, Wenjun, primary, Gorlatov, Sergey, primary, Burke, Steve, primary, Ciccarone, Valentina, primary, Li, Hua, primary, Yang, Yinhua, primary, Son, Tom, primary, Chen, Yan, primary, Easton, Ann N., primary, Li, Jonathan C., primary, Rillema, Jill R., primary, Licea, Monica, primary, Fieger, Claudia, primary, Liang, Tony W., primary, Mather, Jennie P., primary, Koenig, Scott, primary, Stewart, Stanford J., primary, Johnson, Syd, primary, Bonvini, Ezio, primary, and Moore, Paul A., primary

Published
2023
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10. Supplementary Figure 1 from Development of an Fc-Enhanced Anti–B7-H3 Monoclonal Antibody with Potent Antitumor Activity

Author

Loo, Deryk, primary, Alderson, Ralph F., primary, Chen, Francine Z., primary, Huang, Ling, primary, Zhang, Wenjun, primary, Gorlatov, Sergey, primary, Burke, Steve, primary, Ciccarone, Valentina, primary, Li, Hua, primary, Yang, Yinhua, primary, Son, Tom, primary, Chen, Yan, primary, Easton, Ann N., primary, Li, Jonathan C., primary, Rillema, Jill R., primary, Licea, Monica, primary, Fieger, Claudia, primary, Liang, Tony W., primary, Mather, Jennie P., primary, Koenig, Scott, primary, Stewart, Stanford J., primary, Johnson, Syd, primary, Bonvini, Ezio, primary, and Moore, Paul A., primary

Published
2023
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19. P-220: Use of Carfilzomib regimens in patients with Multiple Myeloma refractory to CD38 antibodies: a subgroup analysis from a prospective observational study

Author

Terpos, Evangelos, primary, Caers, Jo, additional, Badelita, Sorina N, additional, Zambello, Renato, additional, Kuehr, Thomas, additional, Katodritou, Eirini, additional, Brescianini, Alessandra, additional, Liang, Tony, additional, Wetten, Sally, additional, and Leleu, Xavier, additional

Published
2021
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20. Influence of Nose Bluntness on Crossflow Instability.

Author

Khan, Arham Amin, Liang, Tony, and Kuehl, Joseph

Abstract

Much work has been focused on the initiation of crossflow instability due to roughness-induced mode excitation. Here we emphasize another aspect of the problem; how changes in nose bluntness (possibly due to ablation or other effects) may also alter the dynamics of crossflow instability via entropy layer modification. The effect of nose bluntness on crossflow instability for a Mach 6 yawed cone is considered at two different angles of attack. Linear parabolized stability equations investigation is performed on crossflow vortices along vortex lines calculated by the inflection point method. It is found that small changes in nose bluntness significantly alter the trajectory of crossflow vortices, the strength of the crossflow instability, and the most unstable wavenumber of the crossflow vortices. These results may be of particular importance to experimentalists studying the effect of ablation on crossflow instability. [ABSTRACT FROM AUTHOR]

Published
2022
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22. Abstract 1832: Development of a splicing modulator-based ADC payload class with immune stimulatory properties for cancer therapy

Author

Mitra, Satyajit K., primary, Jammalamadaka, Vasu, additional, Kang, Jeffrey, additional, Losic, Teodora, additional, Tuffy, Greg, additional, Liang, Tony W., additional, Tipton, Kim, additional, Lopez, Adriana, additional, Savage, Scott, additional, Monteith, William, additional, Haskins, William E., additional, Jurica, Melissa S., additional, Satyal, Sanjeev, additional, and Do, Mary, additional

Published
2021
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28. Safe and Sound (Asleep) : Sleep Pod Safety Perceptions

Author

Pavlakovic, Rachel, Sandhar, Palvi, Tang, Rebecca, Liang, Tony, Ruan, Yingjun, and Kotsos, Nick

Abstract

The purpose of our research was to discover which features of the napping pod environment would be perceived as the most safe. In order to answer this question, we surveyed 103 undergraduate students, all of who are currently studying at the University of British Columbia. The level of safety respondents felt when napping in sleep pods was measured by a survey containing 10 questions, an outline of which is included in appendix A. Respondents were able to rate their felt safety on a scale ranging from 1 (I don’t feel very safe) to 7 (I feel very safe). There was an additional question at the end of the survey, which allowed participants to comment and address any other safety concerns they had regarding the implementation of sleep pods on campus. The results of the survey showed that, while students would generally feel safe napping in sleep pods, the introduction of secure storage for belongings and the inclusion of interior locks on the sleep pods, account for the greatest increase in perceived safety. Disclaimer: “UBC SEEDS provides students with the opportunity to share the findings of their studies, as well as their opinions, conclusions and recommendations with the UBC community. The reader should bear in mind that this is a student project/report and is not an official document of UBC. Furthermore readers should bear in mind that these reports may not reflect the current status of activities at UBC. We urge you to contact the research persons mentioned in a report or the SEEDS Coordinator about the current status of the subject matter of a project/report.”

Published
2019
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32. Neutrophil transepithelial migration: regulation at the apical epithelial surface by Fc-mediated events

Author

REAVES, TITUS A., COLGAN, SEAN P., SELVARAJ, PERIASAMY, POCHET, MILDRED M., WALSH, SHAUN, NUSRAT, ASMA, LIANG, TONY W., MADARA, JAMES L., and PARKOS, CHARLES A.

Subjects
Neutrophils -- Physiological aspects, Cell migration -- Physiological aspects, Epithelial cells -- Physiological aspects, Inflammation -- Physiological aspects, Antibodies -- Physiological aspects, Intestines -- Physiological aspects, Ulcerative colitis -- Physiological aspects, Biological sciences
Abstract

Reaves, Titus A., Sean P. Colgan, Periasamy Selvaraj, Mildred M. Pochet, Shaun Walsh, Asma Nusrat, Tony W. Liang, James L. Madara, and Charles A. Parkos. Neutrophil transepithelial migration: regulation at the apical epithelial surface by Fc-mediated events. Am J Physiol Gastrointest Liver Physiol 280: G746-G754, 2001.--Neutrophil (PMN) transepithelial migration is a major effector of epithelial defense in inflammatory diseases involving mucosal surfaces. However, major receptor-ligand interactions between epithelial cells and PMN remain incompletely characterized. To better define the molecular events involved in PMN interactions with epithelial cells, we produced a monoclonal antibody called g82 that inhibited PMN transepithelial migration in the physiological basolateral-to-apical direction. The g82 antigen localized to the apical surface of human colonic epithelium and was significantly upregulated under inflammatory conditions. Immunoprecipitation revealed two polypeptides of [M.sub.r] 207 and 32 kDa. F[(ab').sub.2] fragments from g82 IgG had no effect on transmigration, suggesting Fc dependence. Further experiments confirmed dependence on the PMN Fc receptor CD32A and that the observed effects were secondary to a failure of PMN to detach from the apical epithelial surface. These Fc-mediated events were epitope specific since binding, isotype-matched antibodies did not affect detachment. These results identify a new mechanism for retention of PMN at the apical epithelial surface following transepithelial migration. This pathway may be important in pathogen clearance and mucosal pathophysiology associated with autoimmunity. intestine; inflammation; ulcerative colitis; epithelial cells

Published
2001

33. Characterization of huJAM: evidence for involvement in cell-cell contact and tight junction regulation

Author

LIANG, TONY W., DEMARCO, RICHARD A., MRSNY, RANDY J., GURNEY, AUSTIN, GRAY, ALANE, HOOLEY, JEFFERY, AARON, HOLLY L., HUANG, ARTHUR, KLASSEN, TONI, TUMAS, DANIEL B., and FONG, SHERMAN

Subjects
Immunoglobulins -- Research, Cell adhesion molecules -- Research, Biological sciences
Abstract

Liang, Tony W., Richard A. DeMarco, Randy J. Mrsny, Austin Gurney, Alane Gray, Jeffery Hooley, Holly L. Aaron, Arthur Huang, Toni Klassen, Daniel B. Tumas, and Sherman Fong. Characterization of huJAM: evidence for involvement in cell-cell contact and tight junction regulation. Am J Physiol Cell Physiol 279: C1733-C1743, 2000.--Cell-cell interactions of the mucosal epithelia are important for the maintenance and establishment of epithelial barrier function. During events of inflammation, such cell-cell interactions are often disrupted, resulting in a leaky epithelial barrier, which in turn can lead to various inflammatory and infective dysfunctions. Human junctional adhesion molecule (huJAM), found on the mucosal epithelia and vascular endothelia of many major organ systems, is a membrane glycoprotein which resolves to a doublet band of ~40 and ~37 kDa under SDS-PAGE analysis, representing differentially glycosylated forms of the same protein, huJAM was localized to the lateral membrane of Caco-2 cells (a human colonic epithelial cell line) monolayers, in an area basolateral of the epithelial tight junctions (TJ). Through functional and biochemical assays, we show huJAM to be able to homotypically associate and to participate in TJ restitution after trypsin-EDTA disruption. Furthermore, we also observed a migration of huJAM expression toward areas of cell-cell contacts during events of cell adhesion and monolayer formation. These qualities makes huJAM a likely player in the regulation of cell-cell contacts and the subsequent formation of TJs. epithelial permeability; junctions; immunoglobulin super-family; adhesion molecule; cell contact

Published
2000

34. Feedback forum

Author

Lambert, Ray, Crane, Abigail, Drummonds, Scott, Rosenbaum, Daniel J., Liang, Tony, O'Brien, Bill, Kuehn, Robert, Sitzberger, Robert G., Santalesa, Rich, Krammin, Paul, Denning, Don, Johnson, Carl E. Jr., Hill, Alice, Wildes, Cliff, Gallagher, Bernard, Elko, Dennis Paul, Henry, J.V., and Russell, Clyde B.

Abstract

Sick of the Sexy Software Dear Editor: As a subscriber to Computer Shopper, I'm writing today to notify you that I will not be renewing my subscription to the magazine. […]

Published
1992

36. Adverse prognosis and distinct progression patterns after concurrent chemoradiotherapy for glioblastoma with synchronous subventricular zone and corpus callosum invasion

Author

Liang, Tony Hsiang-Kuang, primary, Kuo, Sung-Hsin, additional, Wang, Chun-Wei, additional, Chen, Wan-Yu, additional, Hsu, Che-Yu, additional, Lai, Shih-Fan, additional, Tseng, Ham-Min, additional, You, San-Lin, additional, Chen, Chung-Ming, additional, and Tseng, Wen-Yih Isaac, additional

Published
2016
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38. Tumor-Specific Activation of an EGFR-Targeting Probody Enhances Therapeutic Index

Author

Desnoyers, Luc R., primary, Vasiljeva, Olga, additional, Richardson, Jennifer H., additional, Yang, Annie, additional, Menendez, Elizabeth E. M., additional, Liang, Tony W., additional, Wong, Chihunt, additional, Bessette, Paul H., additional, Kamath, Kathy, additional, Moore, Stephen J., additional, Sagert, Jason G., additional, Hostetter, Daniel R., additional, Han, Fei, additional, Gee, Jason, additional, Flandez, Jeanne, additional, Markham, Kate, additional, Nguyen, Margaret, additional, Krimm, Michael, additional, Wong, Kenneth R., additional, Liu, Shouchun, additional, Daugherty, Patrick S., additional, West, James W., additional, and Lowman, Henry B., additional

Published
2013
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39. Abstract 4570: Development of a proteolytically activatable EGFR Probody for cancer therapy.

Author

Desnoyers, Luc R., primary, Yang, Annie, additional, Liang, Tony W., additional, Moore, Stephen, additional, Sagert, Jason, additional, Hostetter, Daniel R., additional, Menendez, Elizabeth, additional, Han, Fei, additional, Krimm, Michael, additional, Wong, Ken, additional, Richardson, Jennifer, additional, West, Jim W., additional, Liu, Shouchun, additional, Vasiljeva, Olga, additional, and Lowman, Henry B., additional

Published
2013
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42. Development of an Fc-Enhanced Anti–B7-H3 Monoclonal Antibody with Potent Antitumor Activity

Author

Loo, Deryk, primary, Alderson, Ralph F., additional, Chen, Francine Z., additional, Huang, Ling, additional, Zhang, Wenjun, additional, Gorlatov, Sergey, additional, Burke, Steve, additional, Ciccarone, Valentina, additional, Li, Hua, additional, Yang, Yinhua, additional, Son, Tom, additional, Chen, Yan, additional, Easton, Ann N., additional, Li, Jonathan C., additional, Rillema, Jill R., additional, Licea, Monica, additional, Fieger, Claudia, additional, Liang, Tony W., additional, Mather, Jennie P., additional, Koenig, Scott, additional, Stewart, Stanford J., additional, Johnson, Syd, additional, Bonvini, Ezio, additional, and Moore, Paul A., additional

Published
2012
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43. Abstract 2725: Preclinical development of an Fc-enhanced anti-B7-H3 monoclonal antibody with potent anti-tumor activity

Author

Loo, Deryk T., primary, Alderson, Ralph, additional, Chen, Francine, additional, Huang, Ling, additional, Zhang, Wenjun, additional, Gorlatov, Sergey, additional, Burke, Steve, additional, Ciccarone, Valentina, additional, Li, Hua, additional, Yang, Yinhua, additional, Son, Thomas, additional, Chen, Yan, additional, Li, Jonathan, additional, Rillema, Jill, additional, Licea, Monica, additional, Liang, Tony, additional, Mather, Jennie P., additional, Koenig, Scott, additional, Stewart, Stanford J., additional, Johnson, Syd, additional, Bonvini, Ezio, additional, and Moore, Paul, additional

Published
2012
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48. Neutrophil Transmigration under Shear Flow Conditions In Vitro Is Junctional Adhesion Molecule-C Independent

Author

Sircar, Monica, primary, Bradfield, Paul F., additional, Aurrand-Lions, Michel, additional, Fish, Richard J., additional, Alcaide, Pilar, additional, Yang, Lin, additional, Newton, Gail, additional, Lamont, Deanna, additional, Sehrawat, Seema, additional, Mayadas, Tanya, additional, Liang, Tony W., additional, Parkos, Charles A., additional, Imhof, Beat A., additional, and Luscinskas, Francis W., additional

Published
2007
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49. The glycotope-specific RAV12 monoclonal antibody induces oncosis in vitro and has antitumor activity against gastrointestinal adenocarcinoma tumor xenografts in vivo

Author

Loo, Deryk, primary, Pryer, Nancy, additional, Young, Peter, additional, Liang, Tony, additional, Coberly, Suzanne, additional, King, Kathleen L., additional, Kang, Key, additional, Roberts, Penny, additional, Tsao, Mary, additional, Xu, Xiaolin, additional, Potts, Beverly, additional, and Mather, Jennie P., additional

Published
2007
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50. Vascular Endothelial-Junctional Adhesion Molecule (VE-JAM)/JAM 2 Interacts with T, NK, and Dendritic Cells Through JAM 3

Author

Liang, Tony W., primary, Chiu, Henry H., additional, Gurney, Austin, additional, Sidle, Aiko, additional, Tumas, Daniel B., additional, Schow, Peter, additional, Foster, Jessica, additional, Klassen, Toni, additional, Dennis, Kathryn, additional, DeMarco, Richard A., additional, Pham, Thinh, additional, Frantz, Gretchen, additional, and Fong, Sherman, additional

Published
2002
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