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173 results on '"Liang, Jiankun"'

6. Single cell RNA-sequencing analysis reveals that N-acetylcysteine partially reverses hepatic immune dysfunction in biliary atresia

Author

Ye, Rongchen, Ma, Sige, Chen, Yan, Shan, Jiarou, Tan, Ledong, Su, Liang, Tong, Yanlu, Zhao, Ziyang, Chen, Hongjiao, Fu, Ming, Guo, Zhipeng, Zuo, Xiaoyu, Yu, Jiakang, Zhong, Wei, Zeng, Jixiao, Liu, Fei, Chai, Chenwei, Guan, Xisi, Wang, Zhe, Liu, Tao, Liang, Jiankun, Zhang, Yan, Shi, Hongguang, Wen, Zhe, Xia, Huimin, and Zhang, Ruizhong

Published
2023
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9. CD177+ cells produce neutrophil extracellular traps that promote biliary atresia

Author

Zhang, Ruizhong, Su, Liang, Fu, Ming, Wang, Zhe, Tan, Ledong, Chen, Hongjiao, Lin, Zefeng, Tong, Yanlu, Ma, Sige, Ye, Rongchen, Zhao, Ziyang, Wang, Ziqing, Chen, Weiyi, Yu, Jiakang, Zhong, Wei, Zeng, Jixiao, Liu, Fei, Chai, Chenwei, Guan, Xisi, Liu, Tao, Liang, Jiankun, Zhu, Yun, Gu, Xiaoqiong, Zhang, Yan, Lui, Vincent C.H., Tam, Paul K.H., Lamb, Jonathan R., Wen, Zhe, Chen, Yan, and Xia, Huimin

Published
2022
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11. Saracatinib inhibits necroptosis and ameliorates psoriatic inflammation by targeting MLKL

Author

Li, Jingyi, primary, Liu, Xingfeng, additional, Liu, Yuanyuan, additional, Huang, Fangmin, additional, Liang, Jiankun, additional, Lin, Yingying, additional, Hu, Fen, additional, Feng, Jianting, additional, Han, Zeteng, additional, Chen, Yushi, additional, Chen, Xuan, additional, Lin, Qiaofa, additional, Wu, Lanqin, additional, and Li, Lisheng, additional

Published
2024
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15. Effects of Dowel Rotation Welding Conditions on Connection Performance for Chinese Fir Dimension Lumbers.

Author

Zhong, Xiao, Li, De, Xu, Xiaoxue, Li, Quan, Yu, Danyun, Wu, Zhigang, Liang, Jiankun, Peng, Jun, Gu, Wen, Zhao, Xin, Yin, Shuang, Yang, Guifen, and Gong, Feiyan

Subjects
LUMBER, WELDING, X-ray photoelectron spectroscopy, FRICTION stir welding, WOOD, FIR, SCANNING electron microscopy
Abstract

In this study, the rotating welding process of Chinese fir (Keteleeriafortunei) in Guizhou, China, was systematically analyzed. The effects of rotating welding conditions, including the dowel-to-guide hole diameter ratio, welding time, depth, base surface, angle, and dowel type, on the performance of welded Chinese fir were explored. Moreover, the physical and chemical changes oftheChinese fir interface during welding were revealed by Fourier-Transform Infrared Spectroscopy (FT-IR), X-ray Photoelectron Spectroscopy (XPS), X-ray Diffraction (XRD), and Scanning Electron Microscopy (SEM). The results indicated the following: (1) The rotating welding technology can quickly achieve a strong connection between wood through friction heat without chemical adhesives and compared with traditional wood connection technology such as gluing or mechanical fixing;it has the advantages of simple operation, high production efficiency; and environmental friendliness. (2) Aftertherotating welding, the wood underwent significant pyrolysis, especially the degradation of hemicellulose. The heat generated in the welding process caused good melting and mechanical interlocking between the dowel and the wall of the guide hole, but it was also accompanied by afriction loss of the dowel and the substrate. (3) The welding parameters affected the wood's connection strength and stability by altering heat production, distribution, transfer, and frictional losses. The impact of the dowel-to-guide hole diameter ratio had a great influence on the connection strength. When the diameter ratio was 1:0.7, the tensile strength was the highest, reaching 2.27 MPa. (4) The analyses of XPS, FTIR, XRD, and SEM proved thatthechemical composition changes at the interface, leading to a more structured crystalline bond and enhanced connection strength due to fiber entanglement and interlocking. This research providesatheoretical and experimental basis forthefurther innovation and development of wood processing technology and provides a new technical path forthegreen manufacturing of wood structure buildings. [ABSTRACT FROM AUTHOR]

Published
2024
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18. Folic acid prevents interferon-induced iron accumulation and ferroptosis and improves liver health in children with biliary atresia

Author

Xu, Yanhui, primary, Chen, Xixi, additional, Fang, Rongli, additional, Ning, Yu, additional, Zhu, Zhijun, additional, Wang, Xiaolei, additional, Xiao, Yunnan, additional, Li, Xiaotian, additional, Ren, Huifang, additional, Zhang, Yanfang, additional, Zuo, Xiaoyu, additional, Chai, Chengwei, additional, Zhong, Kanghua, additional, Liang, Jiankun, additional, Liang, Qifeng, additional, Luo, Yuanyuan, additional, Xu, Yi, additional, Liao, Kaili, additional, He, Qiuming, additional, Tan, Xuying, additional, Ye, Qingqing, additional, Lin, Zefeng, additional, Han, Yang, additional, Luo, Zhenhua, additional, Gu, Xiaoqiong, additional, Zhang, Yan, additional, Sun, Liying, additional, Bai, Fan, additional, Liu, Jinbao, additional, Zhi, Yao, additional, Lv, Junqiang, additional, Lew, Andrew M, additional, Xia, Huimin, additional, Zhou, Wenhao, additional, Wen, Zhe, additional, Chen, Zhanghua, additional, and Zhang, Yuxia, additional

Published
2023
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32. A Composite Whole-Biomass Tannin–Sucrose–Soy Protein Wood Adhesive with High Performance.

Author

Xiao, Guoming, Liang, Jiankun, Wu, Zhigang, Lei, Hong, Gong, Feiyan, Gu, Wen, Tu, Yuan, and Li, De

Subjects
ADHESIVES, WOOD, SOY proteins, INFRARED spectroscopy, X-ray diffraction, WOOD chemistry, THERMAL stability
Abstract

Whole-biomass adhesives are the research hotspot of wood adhesives andcan improve the competitiveness of adhesives. The tannin–sucrose adhesive studied by our research group shows good bonding performance, but poor bonding stability induced by low viscosity. In this study, the tannin–sucrose adhesive was modified by isolated soybean protein (SPI), the effect of the SPI substitution ratio for tannin on the properties of the tannin–sucrose–SPI composite adhesive was investigated, and the bonding mechanism was explored using Fourier-transform infrared spectroscopy (FT-IR), thermogravimetry (TG), X-ray diffraction (XRD), and gas chromatography–mass spectroscopy (GC–MS). The results showed that: (1) when the SPI substitution ratio was above 40%, the viscosity of the composite adhesive increased significantly, which effectively avoided adhesive leakage. (2) The tannin–sucrose–SPI composite adhesive displayed high bonding performance and water resistance. (3) The FTIR and GC–MS results revealed that the curing mechanism of the tannin–sucrose–SPI adhesive was very complicated, but it was certain that the conversion of sucrose into furan compounds, especially 5-hydroxymethylfurfural (5-HMF), was the core of the cross-linking reaction of the adhesive when elevating temperature. (4) The macromolecules and high reactivity of SPI compensated for the shortage of high temperature required for the conversion of sucrose into furanic cross-linkers so that the tannin–sucrose–SPI adhesive experienced an efficient curing reaction at a low temperature, and the reaction degree and thermal stability of the curing product increased. [ABSTRACT FROM AUTHOR]

Published
2023
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33. The Crosslinking Mechanism of Camellia Oleifera Protein Adhesive with Amine Resins by 13C-NMR and ESI-MS.

Author

Deng, Xue, Zhang, Bengang, Liang, Jiankun, Li, Lifen, Wu, Zhigang, and Lei, Hong

Abstract

A new protein wood adhesive was studied with Camellia oleifera protein. Formaldehyde and N-(2)-L-Ala-L-Gln (LAG) were used as the model compounds of amino resins and Camellia oleifera protein, aiming to provide scientific foundations for the improvement and applications of Camellia oleifera protein adhesive by the reaction of model compounds. The experimental results demonstrate that, under alkaline conditions, formaldehyde is easier to react with Camellia oleifera protein by quicker reaction and lower curing temperature. Under acid conditions, amino hydroxymethylated structure of aliphatic series from LAG is difficult to form stable reactive intermediates and further polycondensation. Hydroxymethylation of end acylamino and peptide bond amino from LAG is relatively weak. Under alkaline conditions, the free aliphatic amino and acylamino of LAG both can make hydroxymethylation reaction with formaldehyde. In the polycondensation, hydroxymethyl amide is the initial structure and the reactive intermediate is produced by E1cb reaction of hydroxymethyl amide. Methylene bridge bonds and methylene ether bonds are structures of the polycondensation products, which are competing reactions. The former is mainly formed by the reaction between alkaline reactive intermediate and amino of aliphatic series, and the latter is produced by the reaction of reactive intermediate and amino of hydroxymethyl aliphatic series with hydroxymethyl amide. [ABSTRACT FROM AUTHOR]

Published
2023
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38. Lignin-based adhesive crosslinked by furfuryl alcohol–glyoxal and epoxy resins

Author

Guanben Du, Wenli Wang, Zhigang Wu, Liang Jiankun, Xiaojian Zhou, and Jun Zhang

Subjects
0106 biological sciences, chemistry.chemical_classification, Water resistance, Industrial chemistry, Forestry, 02 engineering and technology, Polymer, Epoxy, 021001 nanoscience & nanotechnology, 01 natural sciences, Furfuryl alcohol, chemistry.chemical_compound, chemistry, 010608 biotechnology, visual_art, visual_art.visual_art_medium, Lignin, Glyoxal, Organic chemistry, General Materials Science, Adhesive, 0210 nano-technology
Abstract

In this work, a novel environmentally friendly lignin-based adhesive crosslinked with a furfuryl alcohol–glyoxal resin and epoxy resin (EPR) was used to bond particleboard. The results of 13C nuclear magnetic resonance and matrix-assisted laser desorption–ionization time-of-flight mass spectroscopy indicated that furfuryl alcohol and glyoxal reacted under acidic conditions and that–CH–(OH)–groups may be involved in the crosslinking of the lignin–furfuryl–glyoxal resin, which also easily crosslinked with EPR. The IB strength of the particleboard bonded with LFG + 9 % EPR adhesive was better than that of the particleboard bonded with lignin–furfuryl alcohol (LF) adhesive. Moreover, the modulus of elasticity of the LFG + 9 % EPR adhesive was higher than that of the LF and phenol-formaldehyde adhesives.

Published
2019

41. Liver Immune Profiling Reveals Pathogenesis and Therapeutics for Biliary Atresia

Author

Wang, Jun, primary, Xu, Yanhui, additional, Chen, Zhanghua, additional, Liang, Jiankun, additional, Lin, Zefeng, additional, Liang, Huiying, additional, Xu, Yiping, additional, Wu, Qi, additional, Guo, Xuanjie, additional, Nie, Junli, additional, Lu, Bingtai, additional, Huang, Bing, additional, Xian, Huifang, additional, Wang, Xiaohui, additional, Wu, Qiang, additional, Zeng, Jixiao, additional, Chai, Chengwei, additional, Zhang, Meixue, additional, Lin, Yuzhen, additional, Zhang, Li, additional, Zhao, Shanmeizi, additional, Tong, Yanlu, additional, Zeng, Liang, additional, Gu, Xiaoqiong, additional, Chen, Zhuang-gui, additional, Yi, Shuhong, additional, Zhang, Tong, additional, Delfouneso, David, additional, Zhang, Yan, additional, Nutt, Stephen L., additional, Lew, Andrew M., additional, Lu, Liwei, additional, Bai, Fan, additional, Xia, Huimin, additional, Wen, Zhe, additional, and Zhang, Yuxia, additional

Published
2020
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43. Research Progress of Coronavirus Based on Bibliometric Analysis

Author

Zhai, Fei, primary, Zhai, Yuxuan, additional, Cong, Chuang, additional, Song, Tingyan, additional, Xiang, Rongwu, additional, Feng, Tianyi, additional, Liang, Zhengxuan, additional, Zeng, Ya, additional, Yang, Jing, additional, Yang, Jie, additional, and Liang, Jiankun, additional

Published
2020
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50. Bowel management program for pediatric postoperative fecal incontinence in China

Author

Wang, Yong, Liang, Huiying, Wu, Qiang, Zheng, Haiqing, Liu, Guangjian, Wen, Zhe, Lan, Menglong, Yu, Jiakang, Zhu, Deli, Liang, Jiankun, Zhang, Jingqi, Xu, Xiaogang, and Xia, Huimin

Subjects
Male, Surgeons, China, Time Factors, efficacy, long-term adherence, Observational Study, Health Care Costs, Length of Stay, Severity of Illness Index, bowel management program, fecal incontinence, Cross-Sectional Studies, Postoperative Complications, Treatment Outcome, Quality of Life, Humans, Patient Compliance, Female, Postoperative Period, Child, Research Article, Follow-Up Studies
Abstract

The purpose of this article is to report the status of the efficacy of and long-term adherence to the Bowel Management Program (BMP) for fecal incontinence (FI) postoperation in China. Children over 3 years of age with FI postoperation referred to our medical center were included in the study. Evaluations were performed before and 2 years after their clinic visit. The cost of bowel care, improvement in incontinence, health-related quality of life, and family functioning with the BMP were analyzed. A total of 48 children with FI were included in our study, of whom 38 were boys. The median treatment fee was 660.1 dollars. The complications included abdominal pain (4 patients, 8%), occasional vomiting (2 patients, 4%), and hypoglycemia (1 patient, 2%). The incontinence status and health-related quality of life improved significantly after the BMP. Despite the good outcome of the BMP, half of the patients discontinued the program. The BMP is an effective approach to manage FI and improve the patients’ quality of life. Poor long-term adherence is currently the main challenge affecting the BMP application in China.

Published
2017

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