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Your search keyword '"Lian, Qing-Quan"' showing total 239 results
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239 results on '"Lian, Qing-Quan"'

31. Comparison of Postoperative Analgesic Effects Between Nalbuphine and Fentanyl in Children Undergoing Adenotonsillectomy: A Prospective, Randomized, Double-Blind, Multicenter Study

Author

Chen, Fang, primary, Wang, Cheng-Yu, additional, Zhang, Jianmin, additional, Wang, Fang, additional, Zhang, Mazhong, additional, Gu, Hongbin, additional, Song, Xingrong, additional, Chen, Jia, additional, Li, Yang, additional, Cai, Yu-Hang, additional, Li, Jun, additional, Lian, Qing-Quan, additional, Wu, Junzheng, additional, and Liu, Hua-Cheng, additional

Published
2020
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35. Additional file 1: of Lipoxin A4 ameliorates lipopolysaccharide-induced lung injury through stimulating epithelial proliferation, reducing epithelial cell apoptosis and inhibits epithelialâ mesenchymal transition

Author

Yang, Jing-Xiang, Li, Ming, Xin-Ou Chen, Lian, Qing-Quan, Wang, Qian, Gao, Fang, Sheng-Wei Jin, and Sheng-Xing Zheng

Subjects
respiratory system
Abstract

Figure S1. LXA4 alleviates inflammation and pulmonary permeability in LPS-induced lung injury. A-E: HE staining of lung. F: injury score of lung. G: wet/dry ratio of lung. Data were presented with means ÂąSD. ***P

Published
2019
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38. Regulation of blood-testis barrier dynamics by the mTORC1/rpS6 signaling complex: An in vitro study.

Author

Li, Lin-Xi, Wu, Si-Wen, Yan, Ming, Lian, Qing-Quan, Ge, Ren-Shan, and Cheng, C

Abstract

During spermatogenesis, developing germ cells that lack the cellular ultrastructures of filopodia and lamellipodia generally found in migrating cells, such as macrophages and fibroblasts, rely on Sertoli cells to support their transport across the seminiferous epithelium. These include the transport of preleptotene spermatocytes across the blood-testis barrier (BTB), but also the transport of germ cells, in particular developing haploid spermatids, across the seminiferous epithelium, that is to and away from the tubule lumen, depending on the stages of the epithelial cycle. On the other hand, cell junctions at the Sertoli cell–cell and Sertoli–germ cell interface also undergo rapid remodeling, involving disassembly and reassembly of cell junctions, which, in turn, are supported by actin- and microtubule-based cytoskeletal remodeling. Interestingly, the underlying mechanism(s) and the involving biomolecule(s) that regulate or support cytoskeletal remodeling remain largely unknown. Herein, we used an in vitro model of primary Sertoli cell cultures that mimicked the Sertoli BTB in vivo overexpressed with the ribosomal protein S6 (rpS6, the downstream signaling protein of mammalian target of rapamycin complex 1 [mTORC1]) cloned into the mammalian expression vector pCI-neo, namely, quadruple phosphomimetic and constitutively active mutant of rpS6 (pCI-neo/p-rpS6-MT) versus pCI-neo/rpS6-WT (wild-type) and empty vector (pCI-neo/Ctrl) for studies. These findings provide compelling evidence that the mTORC1/rpS6 signal pathway exerted its effects to promote Sertoli cell BTB remodeling. This was mediated through changes in the organization of actin- and microtubule-based cytoskeletons, involving changes in the distribution and/or spatial expression of actin- and microtubule-regulatory proteins. [ABSTRACT FROM AUTHOR]

Published
2019
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