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Your search keyword '"Lian, Bi-Jun"' showing total 9 results
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9 results on '"Lian, Bi-Jun"'

5. Simultaneous bilateral laparoscopic cortical-sparing adrenalectomy for bilateral pheochromocytomas in multiple endocrine neoplasia type 2

Author

Qi, Xiao-Ping, Lian, Bi-Jun, Fang, Xu-Dong, Dong, Fang, Li, Feng, Jin, Hang-Yang, Zhang, Ke, Wang, Kang-Er, and Zhang, Yi

Subjects
Surgery
Abstract

Purpose: To assess the feasibility of simultaneous bilateral laparoscopic or open cortical-sparing adrenalectomy (LCSA or OCSA) for bilateral pheochromocytomas (bPHEO) in multiple endocrine neoplasia type 2 (MEN2).Methods: A total of 31 patients (54.8% women) were diagnosed with MEN2 related bPHEO, in who 29 underwent varying specific adrenal surgery. We systematically analyzed and evaluated their clinical profiles, mutation types, tumor histopathologic features, and follow-up records. Results: All 31 patients with bPHEO associated with RET-C634 mutations, as MEN2A (90.3%) and RET-M918T, as MEN2B (9.7%), respectively, were at a median age at initial presentation of 38 years (range, 23–78). Of these, 27 (87.1%) presented with synchronous and other 4 (12.9%) with metachronous. Among 29 underwent initial CSA, and in 23 (79.3%), of whom 18 had SB-LCSA and 5 had SB-OCSA duration of the same anesthesia (synchronous surgery); whereas metachronous CSA was in 6 (20.7%). There were less bleeding volume, and shorter hospitalizations between in SB-LCSA compared with those in SB-OCSA, as well as synchronous surgery versus metachronous (hybrid) surgery (all P < 0.05). An initial bilateral postoperative corticosteroid replacement was necessary in 14 patients (45.2%). During a median follow-up period of 7 years (range, 1.8–23), 3 of these patients (10.3%) showed a persistent/recurrent disease and needed reoperation. Whereas the remaining 2 patients respectively presenting MEN2A died of MTC metastasis or MEN2B declined surgery in who chose waiting watchful.Conclusions: SB-LCSA for treatment of these synchronous bPHEO is safe and feasible, should be recommended as a prioritized surgical approach of choice.

Published
2022
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9. Short-term therapeutic outcomes of robotic-assisted laparoscopic radical prostatectomy for oligometastatic prostate cancer: a propensity score matching study.

Author

Chen H, Qu M, Lian BJ, Wang HF, Wang Y, Dong ZY, Zhu F, Shi ZK, Jia ZP, Sun YH, and Gao X

Subjects
Aged, Humans, Kaplan-Meier Estimate, Magnetic Resonance Imaging, Male, Middle Aged, Propensity Score, Retrospective Studies, Risk Factors, Prostatectomy methods, Prostatic Neoplasms surgery, Robotic Surgical Procedures methods
Abstract

Background: The role of local treatment in oligometastatic prostate cancer (PCa) is gaining interest with the oligometastases hypothesis proposed and the improvement of various surgical methods and techniques. This study aimed to compare the short-term therapeutic outcomes of robotic-assisted laparoscopic radical prostatectomy (RALP) for oligometastatic prostate cancer (OPC) vs. localized PCa using propensity score matching., Methods: Totally 508 consecutive patients underwent RALP as a first-line treatment. The patients were divided into two groups according to oligometastatic state: the OPC group (n = 41) or the localized PCa group (n = 467). Oligometastatic disease was defined as the presence of two or fewer suspicious lesions. The association between the oligometastatic state and therapeutic outcomes of RALP was evaluated, including biochemical recurrence (BCR) and overall survival (OS). A Cox proportional hazards model was used to assess the possible risk factors for BCR., Results: Totally 41 pairs of patients were matched. The median operative time, the median blood loss, the overall positive surgical margin rate, the median post-operative hospital stays, and the post-operative urinary continence recovery rate between the two groups showed no statistical significance. The 4-year BCR survival rates of the OPC group and localized PCa group were 56.7% and 60.8%, respectively, without a significant difference (P = 0.804). The 5-year OS rates were 96.3% and 100%, respectively (P = 0.326). Additionally, the results of Cox regression showed that oligometastatic state was not an independent risk factor for BCR (P = 0.682)., Conclusions: Our findings supported the safety and effectiveness of RALP in OPC. Additionally, oligometastatic state and sites did not have an adverse effect on BCR independently.

Published
2020
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