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1. A Case Report of Infective Endocarditis with Failure of the Empirical Treatment—Q Fever Endocarditis Diagnosed by Metagenomic Next-Generation Sequencing

Author

Lin GS, Zhao MM, Li XQ, and Yu HX

Subjects
q fever, endocarditis, diagnosis, metagenomic next-generation sequencing, Infectious and parasitic diseases, RC109-216
Abstract

Guo-Shuai Lin,* Mao-Mao Zhao,* Xiao-Qing Li, Hong-Xia Yu Department of Infectious Disease, Yantai Yuhuangding Hospital, Yantai, Shandong, 264000, People’s Republic of China*The authors contributed equally to this workCorrespondence: Hong-Xia Yu, Department of Infectious Disease, Yantai Yuhuangding Hospital, Yantai, Shandong, 264000, People’s Republic of China, Tel +86 15053573266, Email yuhongxiag6d@163.comBackground: Infective endocarditis (IE) can be caused by a variety of pathogens. Endocarditis due to the Coxiella burnetii (C. burnetii) infection is common in patients with negative blood culture results and usually occurs in patients with previous valvular heart disease, impaired immune function, and during pregnancy. The diagnosis is difficult based on the conventional diagnostic method, and serious adverse outcomes may occur in the case of delayed diagnosis.Case Report: In the present study, a case of a 43-year-old male patient with previous valvular heart disease was reported. The patient was admitted with a diagnosis of IE, but the etiology was unclear. Accurate diagnosis and treatment were achieved by combining metagenomic next-generation sequencing (mNGS) with Q fever serological antibody assay.Conclusion: Metagenomic next-generation sequencing has been increasingly applied in clinical practice in recent years to detect the DNA or RNA in samples, and this could play a decisive role in the etiological diagnosis of some infectious diseases.Keywords: Q fever, endocarditis, diagnosis, metagenomic next-generation sequencing

Published
2022

2. A Triptolide Loaded HER2-Targeted Nano-Drug Delivery System Significantly Suppressed the Proliferation of HER2-Positive and BRAF Mutant Colon Cancer

Author

Yalikong A, Li XQ, Zhou PH, Qi ZP, Li B, Cai SL, and Zhong YS

Subjects
colon cancer, her2, triptolide, braf mutation, Medicine (General), R5-920
Abstract

Ayimukedisi Yalikong,1,2,* Xu-Quan Li,1,3,* Ping-Hong Zhou,1,2 Zhi-Peng Qi,1,2 Bing Li,1,2 Shi-Lun Cai,1,2 Yun-Shi Zhong1,2 1Endoscopy Center, Zhongshan Hospital of Fudan University, Shanghai, 200032, People’s Republic of China; 2Endoscopy Research Institute of Fudan University, Shanghai, 200032, People’s Republic of China; 3Shanghai Henlius Biopharmaceuticals Co., Ltd., Shanghai, 200033, People’s Republic of China*These authors contributed equally to this workCorrespondence: Shi-Lun Cai; Yun-Shi ZhongZhongshan Hospital of Fudan University, 180 Fenglin Road, Shanghai, 200032, People’s Republic of ChinaEmail caishilun1988@qq.com; zhongyunshi@yahoo.comBackground: Colon cancer (CRC) was a malignant tumor and there were about 25% of patients with tumor metastasis at diagnosis stage. Chemotherapeutic agents for metastatic CRC patients were with great side effects and the clinical treatment results of advanced CRC were still not satisfactory. Human epidermal growth factor receptor 2 (HER2) is overexpressed in some CRC patients and is an effective target for CRC patient treatment. Anti-HER2 therapy had a beneficial role in the treatment of HER2-positive metastatic CRC with fewer side effects. CRC patients with BRAF mutations were resistant to HER2 antibodies treatment. Therefore, there was an urgent need to develop new therapeutic agents.Methods: HER2 targeted nanoparticles (TPLNP) drug delivery system loading triptolide (TPL) were prepared and identified. The effects of TPLNP and free TPL on cell viability, targeting and cell cycle progression on HT29 (BRAF mutation) with HER2 overexpression, were evaluated by Cell Counting Kit-8 (CCK8), Fluorescence Activating Cell Sorter (FACS) and immunofluorescence methods, respectively. The anti-tumor efficacies of TPLNP were evaluated in subcutaneous xenograft model of colon cancer and the survival rate, tumor volume, liver and kidney indexes of tumor-bearing mice were measured.Results: TPLNP was small in nanosize (73.4± 5.2nm) with narrow size distribution (PDI=0.15± 0.02) and favorable zeta potential (pH=9.6, zeta potential: − 57.3± 6.69mV; pH=7.0, zeta potential: − 28.7± 5.1mV; pH=5.6, zeta potential: − 21.1± 4.73mV). Comparing with free TPL treatment group, TPLNP developed stranger colon cancer-killing efficiency in a dose- and time-dependent manner detected with CCK8 method; achieved good in vitro colon cancer targeting detected with flow cytometry and immunofluorescence experiments; enhanced more HT29-HER2 apoptosis and induced more cell cycle arrested in G1-S phase detected with FACS in vitro. As for in vivo antitumor response, TPLNP remarkably inhibited the growth of colon cancer in the colon cancer xenograft model, significantly improved the survival rate and did not exhibit significant liver and kidney toxicity in contrast with free TPL in vivo.Conclusion: TPLNP was effectively against colon cancer with HER2 overexpression and BRAF mutation in pre-clinical models. In summary, the TPLNP appeared to be a promising treatment option for CRC in clinical application based on improved efficacy and the favorable safety profile.Keywords: colon cancer, HER2, triptolide, BRAF mutation

Published
2021

3. Simultaneous Infection of the Skin Surface and Dermal Tissue with Two Different Fungus Mimicking Pyoderma Gangrenosum: A Case Report

Author

Jia QY, Song YG, Li XQ, Mu ZL, Li RY, and Li HM

Subjects
cutaneous mucormycosis, trichophyton rubrum infection, cutaneous infection, lower leg, steroid therapy, Dermatology, RL1-803
Abstract

Qiu-Yu Jia,1 Ying-Gai Song,2 Xiang-Qian Li,1 Zhang-Lei Mu,1 Ruo-Yu Li,2 Hou-Min Li1 1Department of Dermatology, Peking University People’s Hospital, Beijing, People’s Republic of China; 2Department of Dermatology, Peking University the First Hospital, Beijing, People’s Republic of ChinaCorrespondence: Hou-Min LiDepartment of Dermatology, Peking University People’s Hospital, No. 11 Xizhimen South Street, Xicheng District, Beijing, 100044, People’s Republic of ChinaTel +86 (424) 390-2625Email lhoumin@sina.cnAbstract: Mucormycosis is an opportunistic fungal infection driven by subphylum Mucormycotina. Cutaneous mucormycosis is the third most common presentation of mucormycosis, and its characterized presentation is an indurated plaque that rapidly evolves to necrosis. Trichophyton rubrum is one of the most common dermatophytes that mainly cause superficial infections and seldom induce deep infections. The present report presents a case of cutaneous fungal infection, in which two kinds of fungus were isolated, and the skin lesion mimicked pyoderma gangrenosum. Trichophyton rubrum was isolated from the crust and hyphae of subphylum Mucormycotina were found in dermal tissue. The irregular systemic and topical use of steroid therapy is the possible cause of the mixed fungal infection in this patient, suggesting the importance of regular steroid therapy.Keywords: cutaneous mucormycosis, Trichophyton rubrum infection, cutaneous infection, lower leg, steroid therapy

Published
2021

4. The Regulating Mechanism of Chrysophanol on Protein Level of CaM-CaMKIV to Protect PC12 Cells Against Aβ25-35-Induced Damage

Author

Ye T, Gao HW, Xuan WT, Ye S, Zhou P, Li XQ, Wang Y, Song H, Liu YY, and Cai B

Subjects
chrysophanol, alzheimer’s disease, cam-camkk-camkⅳ, p-tau, Therapeutics. Pharmacology, RM1-950
Abstract

Ting Ye,1,* Hua-Wu Gao,1,* Wei-Ting Xuan,1 Shu Ye,1– 3 Peng Zhou,1– 3 Xin-Quan Li,1 Yan Wang,1– 3 Hang Song,1,2 Yan-Yan Liu,1,2 Biao Cai1– 3 1School of Integrated Chinese and Western Medicine, Anhui University of Chinese Medicine, Hefei 230012, People’s Republic of China; 2Institute of Integrated Chinese and Western Medicine, Anhui Academy of Chinese Medicine, Hefei 230012, People’s Republic of China; 3Anhui Province Key Laboratory of Chinese Medicinal Formula, Hefei 230012, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yan-Yan Liu; Biao Cai Email liuyan2027@163.com; caibiao@ahtcm.edu.cnObjective: To investigate the neuroprotective effect of chrysophanol (CHR) on PC12 treated with Aβ25-35, and the involved mechanism.Methods: After the establishment of an AD cell model induced by Aβ25-35, the cell survival rate was detected by MTT, cell apoptosis was assayed by Hoechst 33342 staining, mRNA expressions of calmodulin (CaM), calcium/calmodulin-dependent protein kinase kinase (CaMKK), calcium/calmodulin-dependent protein kinase IV (CaMKIV) and tau (MAPT; commonly known as tau) were determined by qRT-PCR, and protein levels of CaM, CaMKK, CaMKIV, phospho-CaMKIV (p-CaMKIV), tau and phospho-tau (p-tau) were detected by Western blot analysis.Results: When pretreated with CHR before exposure to Aβ25-35, PC12 cells showed that increased cell viability and reduced apoptosis. The qRT-PCR results indicated that the deposition of Aβ25-35 triggers a decrease in levels of CaM, CaMKK, CaMKIV, and tau in PC12 cells. In addition, Western blot results also suggested that Aβ25-35 decreases the protein expression of CaM, CaMKK, CaMKIV, p-CaMKIV, and the ratio of p-tau to tau in PC12 cells. However, the above effects were significantly alleviated after the treatment of CHR.Conclusion: CHR plays a neuroprotective role in AD though decreasing the protein level of CaM-CaMKK-CaMKIV and the expression of p-tau downstream.Keywords: chrysophanol, Alzheimer’s disease, CaM-CaMKK-CaMKIV, p-tau

Published
2020

5. Nanosized functional miRNA liposomes and application in the treatment of TNBC by silencing Slug gene

Author

Yan Y, Li XQ, Duan JL, Bao CJ, Cui YN, Su ZB, Xu JR, Luo Q, Chen M, Xie Y, and Lu WL

Subjects
functional miRNA liposomes, Slug, TGF-β1/Smad, gene therapy, TNBC, Medicine (General), R5-920
Abstract

Yan Yan, Xue-Qi Li, Jia-Lun Duan, Chun-Jie Bao, Yi-Nuo Cui, Zhan-Bo Su, Jia-Rui Xu, Qian Luo, Ming Chen, Ying Xie, Wan-Liang LuState Key Laboratory of Natural and Biomimetic Drugs, Beijing Key Laboratory of Molecular Pharmaceutics and New Drug System, and School of Pharmaceutical Sciences, Peking University, Beijing, People’s Republic of ChinaBackground: Neo-adjuvant chemotherapy is an effective strategy for improving treatment of breast cancers. However, the efficacy of this treatment strategy is limited for treatment of triple negative breast cancer (TNBC). Gene therapy may be a more effective strategy for improving the prognosis of TNBC.Methods: A novel 25 nucleotide sense strand of miRNA was designed to treat TNBC by silencing the Slug gene, and encapsulated into DSPE-PEG2000-tLyp-1 peptide-modified functional liposomes. The efficacy of miRNA liposomes was evaluated on invasive TNBC cells and TNBC cancer-bearing nude mice. Furthermore, functional vinorelbine liposomes were constructed to investigate the anticancer effects of combined treatment.Results: The functional miRNA liposomes had a round shape and were nanosized (120 nm). Functional miRNA liposomes were effectively captured by TNBC cells in vitro and were target to mitochondria. Treatment with functional liposomes silenced the expression of Slug and Slug protein, inhibited the TGF-β1/Smad pathway, and inhibited invasiveness and growth of TNBC cells. In TNBC cancer-bearing mice, functional miRNA liposomes exerted a stronger anticancer effect than functional vinorelbine liposomes, and combination therapy with these two formulations resulted in nearly complete inhibition of tumor growth. Preliminary safety evaluations indicated that the functional miRNA liposomes did not affect body weight or cause damage to any major organs. Furthermore, the functional liposomes significantly increased the half-life of the drug in the blood of cancer-bearing nude mice, and increased drug accumulation in breast cancer tissues.Conclusion: In this study, we constructed novel functional miRNA liposomes. These liposomes silenced Slug expression and inhibited the TGF-β1/Smad pathway in TNBC cells, and enhanced anticancer efficacy in mice using combined chemotherapy. Hence, the present study demonstrated a promising strategy for gene therapy of invasive breast cancer.Keywords: functional miRNA liposomes, Slug, TGF-β1/Smad, gene therapy, TNBC

Published
2019

6. Bioabsorbable self-retaining PLA/nano-sized β-TCP cervical spine interbody fusion cage in goat models: an in vivo study

Author

Cao L, Chen Q, Jiang LB, Yin XF, Bian C, Wang HR, Ma YQ, Li XQ, Li XL, and Dong J

Subjects
goat, cervical spine cages, bioabsorbable, PLA, β-TCP, self-retaining, Medicine (General), R5-920
Abstract

Lu Cao,1,* Qian Chen,1,* Li-Bo Jiang,1,* Xiao-Fan Yin,1,2 Chong Bian,1 Hui-Ren Wang,1 Yi-Qun Ma,1 Xiang-Qian Li,1 Xi-Lei Li,1 Jian Dong1 1Department of Orthopaedic Surgery, Zhongshan Hospital, 2Department of Orthopaedic Surgery, Minhang Hospital, Fudan University, Shanghai, China *These authors contributed equally to this work Study design: This is an experimental animal study.Objective: The objective of this study was to compare an anterior cervical discectomy and interbody fusion of a novel polylactide/nano-sized β-tricalcium phosphate (PLA/nβ-TCP) bioabsorbable self-retaining cervical fusion cage (BCFC) with an autologous bone graft and polyetheretherketone (PEEK) cages.Background: Although PLA cervical cages have potential advantages compared with traditional materials, they are not currently routinely used in spine surgery because of undesirable effects such as the lack of osteoconductivity and osteolysis around the implant. This study involved the manufacturing of a bioabsorbable cage from PLA/nβ-TCP that was then used as a device for anterior cervical discectomy and fusion (ACDF) on a goat cervical spine fusion model.Materials and methods: Eighteen goats underwent C3/C4 discectomy and were randomly divided into three groups based on the following methods: Group A (n=6), an autologous bone graft; Group B (n=6), PEEK cage filled with an autologous graft; and Group C (n=6), BCFC filled with an autologous iliac bone. Radiography was performed preoperatively and postoperatively and at 1, 4, 8, and 12 weeks after the operation. Disc space height (DSH) was measured at the same time. After 12 weeks, the fused segments were harvested and evaluated with functional radiographic views, biomechanical testing, and histological analyses.Results: Over a 12-week period, the BCFC and PEEK cage groups exhibited significantly higher DSH values than the bone graft group. Additionally, the BCFC group yielded a significantly lower range of motion in axial rotation than both the autologous bone graft and PEEK cage groups. A histologic evaluation revealed an increased intervertebral bone volume/total volume ratio and better interbody fusion in the BCFC group than in the other groups.Conclusion: The BCFC device exhibited better results than the autologous bone graft and PEEK cages in single-level ACDF models in vivo. This device may be a potential alternative to the current PEEK cages. Keywords: goat, cervical spine cages, bioabsorbable, PLA, β-TCP, self-retaining

Published
2017

7. The use of functional epirubicin liposomes to induce programmed death in refractory breast cancer

Author

Liu L, Mu LM, Yan Y, Wu JS, Hu YJ, Bu YZ, Zhang JY, Liu R, Li XQ, and Lu WL

Subjects
Mitochondria, drug delivery, apoptosis, efficacy, refractory breast cancer., Medicine (General), R5-920
Abstract

Lei Liu, Li-Min Mu, Yan Yan, Jia-Shuan Wu, Ying-Jie Hu, Ying-Zi Bu, Jing-Ying Zhang, Rui Liu, Xue-Qi Li, Wan-Liang Lu Beijing Key Laboratory of Molecular Pharmaceutics and New Drug System, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, People’s Republic of China Abstract: Currently, chemotherapy is less efficient in controlling the continued development of breast cancer because it cannot eliminate extrinsic and intrinsic refractory cancers. In this study, mitochondria were modified by functional epirubicin liposomes to eliminate refractory cancers through initiation of an apoptosis cascade. The efficacy and mechanism of epirubicin liposomes were investigated on human breast cancer cells in vitro and in vivo using flow cytometry, confocal microscopy, high-content screening system, in vivo imaging system, and tumor inhibition in mice. Mechanistic studies revealed that the liposomes could target the mitochondria, activate the apoptotic enzymes caspase 8, 9, and 3, upregulate the proapoptotic protein Bax while downregulating the antiapoptotic protein Mcl-1, and induce the generation of reactive oxygen species (ROS) through an apoptosis cascade. In xenografted mice bearing breast cancer, the epirubicin liposomes demonstrated prolonged blood circulation, significantly increased accumulation in tumor tissue, and robust anticancer efficacy. This study demonstrated that functional epirubicin liposomes could significantly induce programmed death of refractory breast cancer by activating caspases and ROS-related apoptotic signaling pathways, in addition to the direct killing effect of the anticancer drug itself. Thus, we present a simple nanomedicine strategy to treat refractory breast cancer. Keywords: mitochondria, drug delivery, apoptosis, efficacy, signaling pathway

Published
2017

8. Near-infrared light-triggered theranostics for tumor-specific enhanced multimodal imaging and photothermal therapy

Author

Wu B, Wan B, Lu ST, Deng K, Li XQ, Wu BL, Li YS, Liao RF, Huang SW, and Xu HB

Subjects
light-triggered, near infrared light, tumor-specific, multimodal imaging, photothermal therapy, Medicine (General), R5-920
Abstract

Bo Wu,1,* Bing Wan,2,* Shu-Ting Lu,1 Kai Deng,3 Xiao-Qi Li,1 Bao-Lin Wu,1 Yu-Shuang Li,1 Ru-Fang Liao,1 Shi-Wen Huang,3 Hai-Bo Xu1,2 1Department of Radiology, Zhongnan Hospital of Wuhan University, 2Department of Radiology, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, 3Department of Chemistry, Key Laboratory of Biomedical Polymers, Ministry of Education, Wuhan University, Wuhan, People’s Republic of China *These authors contributed equally to this work Abstract: The major challenge in current clinic contrast agents (CAs) and chemotherapy is the poor tumor selectivity and response. Based on the self-quench property of IR820 at high concentrations, and different contrast effect ability of Gd-DOTA between inner and outer of liposome, we developed “bomb-like” light-triggered CAs (LTCAs) for enhanced CT/MRI/FI multimodal imaging, which can improve the signal-to-noise ratio of tumor tissue specifically. IR820, Iohexol and Gd-chelates were firstly encapsulated into the thermal-sensitive nanocarrier with a high concentration. This will result in protection and fluorescence quenching. Then, the release of CAs was triggered by near-infrared (NIR) light laser irradiation, which will lead to fluorescence and MRI activation and enable imaging of inflammation. In vitro and in vivo experiments demonstrated that LTCAs with 808 nm laser irradiation have shorter T1 relaxation time in MRI and stronger intensity in FI compared to those without irradiation. Additionally, due to the high photothermal conversion efficiency of IR820, the injection of LTCAs was demonstrated to completely inhibit C6 tumor growth in nude mice up to 17 days after NIR laser irradiation. The results indicate that the LTCAs can serve as a promising platform for NIR-activated multimodal imaging and photothermal therapy. Keywords: light triggered, near-infrared light, tumor-specific, multimodal imaging, photothermal therapy, contrast agents

Published
2017

9. Photothermal therapy of cancer cells using novel hollow gold nanoflowers

Author

Han J, Li JR, Jia WF, Yao LM, Li XQ, Jiang L, and Tian Y

Subjects
Medicine (General), R5-920
Abstract

Jing Han,1 Jinru Li,1 Wenfeng Jia,1 Liangming Yao,2 Xiaoqin Li,1 Long Jiang,1 Yong Tian21Beijing National Laboratory for Molecular Sciences, Institute of Chemistry, 2Beijing Key Laboratory of Noncoding RNA, Institute of Biophysics, Chinese Academy of Sciences, Beijing, People's Republic of ChinaAbstract: This article presents a new strategy for fabricating large gold nanoflowers (AuNFs) that exhibit high biological safety under visible light and very strong photothermal cytotoxicity to HeLa cells under irradiation with near-infrared (NIR) light. This particular type of AuNF was constructed using vesicles produced from a multiamine head surfactant as a template followed by depositing gold nanoparticles (AuNPs) and growing their crystallites on the surface of vesicles. The localized surface plasmon-resonance spectrum of this type of AuNF can be easily modulated to the NIR region by controlling the size of the AuNFs. When the size of the AuNFs increased, biosafety under visible light improved and cytotoxicity increased under NIR irradiation. Experiments in vitro with HeLa cells and in vivo with small mice have been carried out, with promising results. The mechanism for this phenomenon is based on the hypothesis that it is difficult for larger AuNFs to enter the cell without NIR irradiation, but they enter the cell easily at the higher temperatures caused by NIR irradiation. We believe that these effects will exist in other types of noble metallic NPs and cancer cells. In addition, the affinity between AuNPs and functional biomolecules, such as aptamers and biomarkers, will make this type of AuNF a good recognition device in cancer diagnosis and therapy.Keywords: HeLa cells, endocytosis, cytotoxicity, AuNFs, NIR, cancer therapy

Published
2014

10. Improved Measurement of the Evolution of the Reactor Antineutrino Flux and Spectrum at Daya Bay

Author

An, FP, Bai, WD, Balantekin, AB, Bishai, M, Blyth, S, Cao, GF, Cao, J, Chang, JF, Chang, Y, Chen, HS, Chen, HY, Chen, SM, Chen, Y, Chen, YX, Cheng, J, Cheng, Y-C, Cheng, ZK, Cherwinka, JJ, Chu, MC, Cummings, JP, Dalager, O, Deng, FS, Ding, YY, Diwan, MV, Dohnal, T, Dolzhikov, D, Dove, J, Dugas, KV, Duyang, HY, Dwyer, DA, Gallo, JP, Gonchar, M, Gong, GH, Gong, H, Gu, WQ, Guo, JY, Guo, L, Guo, XH, Guo, YH, Guo, Z, Hackenburg, RW, Han, Y, Hans, S, He, M, Heeger, KM, Heng, YK, Hor, YK, Hsiung, YB, Hu, BZ, Hu, JR, Hu, T, Hu, ZJ, Huang, HX, Huang, JH, Huang, XT, Huang, YB, Huber, P, Jaffe, DE, Jen, KL, Ji, XL, Ji, XP, Johnson, RA, Jones, D, Kang, L, Kettell, SH, Kohn, S, Kramer, M, Langford, TJ, Lee, J, Lee, JHC, Lei, RT, Leitner, R, Leung, JKC, Li, F, Li, HL, Li, JJ, Li, QJ, Li, RH, Li, S, Li, SC, Li, WD, Li, XN, Li, XQ, Li, YF, Li, ZB, Liang, H, Lin, CJ, Lin, GL, Lin, S, Ling, JJ, Link, JM, Littenberg, L, Littlejohn, BR, Liu, JC, Liu, JL, Liu, JX, Lu, C, Lu, HQ, and Luk, KB

Subjects
Nuclear and Plasma Physics, Particle and High Energy Physics, Physical Sciences, Nuclear Reactors, Uranium, Daya Bay Collaboration, Mathematical Sciences, Engineering, General Physics, Mathematical sciences, Physical sciences
Abstract

Reactor neutrino experiments play a crucial role in advancing our knowledge of neutrinos. In this Letter, the evolution of the flux and spectrum as a function of the reactor isotopic content is reported in terms of the inverse-beta-decay yield at Daya Bay with 1958 days of data and improved systematic uncertainties. These measurements are compared with two signature model predictions: the Huber-Mueller model based on the conversion method and the SM2018 model based on the summation method. The measured average flux and spectrum, as well as the flux evolution with the ^{239}Pu isotopic fraction, are inconsistent with the predictions of the Huber-Mueller model. In contrast, the SM2018 model is shown to agree with the average flux and its evolution but fails to describe the energy spectrum. Altering the predicted inverse-beta-decay spectrum from ^{239}Pu fission does not improve the agreement with the measurement for either model. The models can be brought into better agreement with the measurements if either the predicted spectrum due to ^{235}U fission is changed or the predicted ^{235}U, ^{238}U, ^{239}Pu, and ^{241}Pu spectra are changed in equal measure.

Published
2023

11. Precision Measurement of Reactor Antineutrino Oscillation at Kilometer-Scale Baselines by Daya Bay

Author

An, FP, Bai, WD, Balantekin, AB, Bishai, M, Blyth, S, Cao, GF, Cao, J, Chang, JF, Chang, Y, Chen, HS, Chen, HY, Chen, SM, Chen, Y, Chen, YX, Chen, ZY, Cheng, J, Cheng, ZK, Cherwinka, JJ, Chu, MC, Cummings, JP, Dalager, O, Deng, FS, Ding, YY, Ding, XY, Diwan, MV, Dohnal, T, Dolzhikov, D, Dove, J, Duyang, HY, Dwyer, DA, Gallo, JP, Gonchar, M, Gong, GH, Gong, H, Gu, WQ, Guo, JY, Guo, L, Guo, XH, Guo, YH, Guo, Z, Hackenburg, RW, Han, Y, Hans, S, He, M, Heeger, KM, Heng, YK, Hor, YK, Hsiung, YB, Hu, BZ, Hu, JR, Hu, T, Hu, ZJ, Huang, HX, Huang, JH, Huang, XT, Huang, YB, Huber, P, Jaffe, DE, Jen, KL, Ji, XL, Ji, XP, Johnson, RA, Jones, D, Kang, L, Kettell, SH, Kohn, S, Kramer, M, Langford, TJ, Lee, J, Lee, JHC, Lei, RT, Leitner, R, Leung, JKC, Li, F, Li, HL, Li, JJ, Li, QJ, Li, RH, Li, S, Li, SC, Li, WD, Li, XN, Li, XQ, Li, YF, Li, ZB, Liang, H, Lin, CJ, Lin, GL, Lin, S, Ling, JJ, Link, JM, Littenberg, L, Littlejohn, BR, Liu, JC, Liu, JL, Liu, JX, Lu, C, Lu, HQ, Luk, KB, and Z., B

Subjects
Nuclear and Plasma Physics, Particle and High Energy Physics, Physical Sciences, Daya Bay Collaboration, Mathematical Sciences, Engineering, General Physics, Mathematical sciences, Physical sciences
Abstract

We present a new determination of the smallest neutrino mixing angle θ_{13} and the mass-squared difference Δm_{32}^{2} using a final sample of 5.55×10^{6} inverse beta-decay (IBD) candidates with the final-state neutron captured on gadolinium. This sample is selected from the complete dataset obtained by the Daya Bay reactor neutrino experiment in 3158 days of operation. Compared to the previous Daya Bay results, selection of IBD candidates has been optimized, energy calibration refined, and treatment of backgrounds further improved. The resulting oscillation parameters are sin^{2}2θ_{13}=0.0851±0.0024, Δm_{32}^{2}=(2.466±0.060)×10^{-3}  eV^{2} for the normal mass ordering or Δm_{32}^{2}=-(2.571±0.060)×10^{-3}  eV^{2} for the inverted mass ordering.

Published
2023

12. First Measurement of High-Energy Reactor Antineutrinos at Daya Bay

Author

An, FP, Bai, WD, Balantekin, AB, Bishai, M, Blyth, S, Cao, GF, Cao, J, Chang, JF, Chang, Y, Chen, HS, Chen, HY, Chen, SM, Chen, Y, Chen, YX, Cheng, J, Cheng, ZK, Cherwinka, JJ, Chu, MC, Cummings, JP, Dalager, O, Deng, FS, Ding, YY, Diwan, MV, Dohnal, T, Dolzhikov, D, Dove, J, Dwyer, DA, Gallo, JP, Gonchar, M, Gong, GH, Gong, H, Gu, WQ, Guo, JY, Guo, L, Guo, XH, Guo, YH, Guo, Z, Hackenburg, RW, Hans, S, He, M, Heeger, KM, Heng, YK, Hor, YK, Hsiung, YB, Hu, BZ, Hu, JR, Hu, T, Hu, ZJ, Huang, HX, Huang, JH, Huang, XT, Huang, YB, Huber, P, Jaffe, DE, Jen, KL, Ji, XL, Ji, XP, Johnson, RA, Jones, D, Kang, L, Kettell, SH, Kohn, S, Kramer, M, Langford, TJ, Lee, J, Lee, JHC, Lei, RT, Leitner, R, Leung, JKC, Li, F, Li, HL, Li, JJ, Li, QJ, Li, RH, Li, S, Li, SC, Li, WD, Li, XN, Li, XQ, Li, YF, Li, ZB, Liang, H, Lin, CJ, Lin, GL, Lin, S, Ling, JJ, Link, JM, Littenberg, L, Littlejohn, BR, Liu, JC, Liu, JL, Liu, JX, Lu, C, Lu, HQ, Luk, KB, Z., B, B., X, Y., X, Q., Y, and Mandujano, RC

Subjects
Nuclear and Plasma Physics, Particle and High Energy Physics, Synchrotrons and Accelerators, Physical Sciences, Affordable and Clean Energy, Daya Bay Collaboration, Mathematical Sciences, Engineering, General Physics, Mathematical sciences, Physical sciences
Abstract

This Letter reports the first measurement of high-energy reactor antineutrinos at Daya Bay, with nearly 9000 inverse beta decay candidates in the prompt energy region of 8-12 MeV observed over 1958 days of data collection. A multivariate analysis is used to separate 2500 signal events from background statistically. The hypothesis of no reactor antineutrinos with neutrino energy above 10 MeV is rejected with a significance of 6.2 standard deviations. A 29% antineutrino flux deficit in the prompt energy region of 8-11 MeV is observed compared to a recent model prediction. We provide the unfolded antineutrino spectrum above 7 MeV as a data-based reference for other experiments. This result provides the first direct observation of the production of antineutrinos from several high-Q_{β} isotopes in commercial reactors.

Published
2022

13. Antineutrino energy spectrum unfolding based on the Daya Bay measurement and its applications * *Supported in part by the Ministry of Science and Technology of China, the U.S. Department of Energy, the Chinese Academy of Sciences, the CAS Center for Excellence in Particle Physics, the National Natural Science Foundation of China, the Guangdong provincial government, the Shenzhen municipal government, the China General Nuclear Power Group, the Research Grants Council of the Hong Kong Special Administrative Region of China, the Ministry of Education in TW, the U.S. National Science Foundation, the Ministry of Education, Youth, and Sports of the Czech Republic, the Charles University Research Centre UNCE, the Joint Institute of Nuclear Research in Dubna, Russia, the National Commission of Scientific and Technological Research of Chile

Author

An, FP, Balantekin, AB, Bishai, M, Blyth, S, Cao, GF, Cao, J, Chang, JF, Chang, Y, Chen, HS, Chen, SM, Chen, Y, Chen, YX, Cheng, J, Cheng, ZK, Cherwinka, JJ, Chu, MC, Cummings, JP, Dalager, O, Deng, FS, Ding, YY, Diwan, MV, Dohnal, T, Dolzhikov, D, Dove, J, Dvořák, M, Dwyer, DA, Gallo, JP, Gonchar, M, Gong, GH, Gong, H, Grassi, M, Gu, WQ, Guo, JY, Guo, L, Guo, XH, Guo, YH, Guo, Z, Hackenburg, RW, Hans, S, He, M, Heeger, KM, Heng, YK, Hor, YK, Hsiung, YB, Hu, BZ, Hu, JR, Hu, T, Hu, ZJ, Huang, HX, Huang, JH, Huang, XT, Huang, YB, Huber, P, Jaffe, DE, Jen, KL, Ji, XL, Ji, XP, Johnson, RA, Jones, D, Kang, L, Kettell, SH, Kohn, S, Kramer, M, Langford, TJ, Lee, J, Lee, JHC, Lei, RT, Leitner, R, Leung, JKC, Li, F, Li, HL, Li, JJ, Li, QJ, Li, RH, Li, S, Li, SC, Li, WD, Li, XN, Li, XQ, Li, YF, Li, ZB, Liang, H, Lin, CJ, Lin, GL, Lin, S, Ling, JJ, Link, JM, Littenberg, L, Littlejohn, BR, Liu, JC, Liu, JL, Liu, JX, Lu, C, Lu, HQ, Luk, KB, Z., B, B., X, Y., X, Q., Y, and Mandujano, RC

Subjects
Nuclear and Plasma Physics, Synchrotrons and Accelerators, Physical Sciences, Affordable and Clean Energy, reactor antineutrino, energy spectrum, Daya Bay, application, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Nuclear & Particles Physics, Atomic, molecular and optical physics, Particle and high energy physics
Abstract

The prediction of reactor antineutrino spectra will play a crucial role as reactor experiments enter the precision era. The positron energy spectrum of 3.5 million antineutrino inverse beta decay reactions observed by the Daya Bay experiment, in combination with the fission rates of fissile isotopes in the reactor, is used to extract the positron energy spectra resulting from the fission of specific isotopes. This information can be used to produce a precise, data-based prediction of the antineutrino energy spectrum in other reactor antineutrino experiments with different fission fractions than Daya Bay. The positron energy spectra are unfolded to obtain the antineutrino energy spectra by removing the contribution from detector response with the Wiener-SVD unfolding method. Consistent results are obtained with other unfolding methods. A technique to construct a data-based prediction of the reactor antineutrino energy spectrum is proposed and investigated. Given the reactor fission fractions, the technique can predict the energy spectrum to a 2% precision. In addition, we illustrate how to perform a rigorous comparison between the unfolded antineutrino spectrum and a theoretical model prediction that avoids the input model bias of the unfolding method.

Published
2021

14. Search for electron-Antineutrinos associated with gravitational-wave events GW150914, GW151012, GW151226, GW170104, GW170608, GW170814, and GW170817 at Daya Bay

Author

An, FP, Balantekin, AB, Band, HR, Bishai, M, Blyth, S, Cao, GF, Cao, J, Chang, JF, Chang, Y, Chen, HS, Chen, SM, Chen, Y, Chen, YX, Cheng, J, Cheng, ZK, Cherwinka, JJ, Chu, MC, Cummings, JP, Dalager, O, Deng, FS, Ding, YY, Diwan, MV, Dohnal, T, Dove, J, Dvořák, M, Dwyer, DA, Gallo, JP, Gonchar, M, Gong, GH, Gong, H, Gu, WQ, Guo, JY, Guo, L, Guo, XH, Guo, YH, Guo, Z, Hackenburg, RW, Hans, S, He, M, Heeger, KM, Heng, YK, Higuera, A, Hor, YK, Hsiung, YB, Hu, BZ, Hu, JR, Hu, T, Hu, ZJ, Huang, HX, Huang, XT, Huang, YB, Huber, P, Jaffe, DE, Jen, KL, Ji, XL, Ji, XP, Johnson, RA, Jones, D, Kang, L, Kettell, SH, Kohn, S, Kramer, M, Langford, TJ, Lee, J, Lee, JHC, Lei, RT, Leitner, R, Leung, JKC, Li, F, Li, JJ, Li, QJ, Li, S, Li, SC, Li, WD, Li, XN, Li, XQ, Li, YF, Li, ZB, Liang, H, Lin, CJ, Lin, GL, Lin, S, Ling, JJ, Link, JM, Littenberg, L, Littlejohn, BR, Liu, JC, Liu, JL, Lu, C, Lu, HQ, Lu, JS, Luk, KB, Ma, XB, Ma, XY, Ma, YQ, Marshall, C, Martinez Caicedo, DA, McDonald, KT, McKeown, RD, and Meng, Y

Subjects
gravitational waves, electron-antineutrinos, fluence, upper limit, astro-ph.HE, hep-ex, physics.ins-det, Nuclear & Particles Physics, Atomic, Molecular, Nuclear, Particle and Plasma Physics
Abstract

The establishment of a possible connection between neutrino emission and gravitational-wave (GW) bursts is important to our understanding of the physical processes that occur when black holes or neutron stars merge. In the Daya Bay experiment, using the data collected from December 2011 to August 2017, a search was performed for electron-Antineutrino signals that coincided with detected GW events, including GW150914, GW151012, GW151226, GW170104, GW170608, GW170814, and GW170817. We used three time windows of 10, 500, and 1000 s relative to the occurrence of the GW events and a neutrino energy range of 1.8 to 100 MeV to search for correlated neutrino candidates. The detected electron-Antineutrino candidates were consistent with the expected background rates for all the three time windows. Assuming monochromatic spectra, we found upper limits (90% confidence level) of the electron-Antineutrino fluence of (1.13-2.44)×1011 cm-2 at 5 MeV to 8.0×107 cm-2 at 100 MeV for the three time windows. Under the assumption of a Fermi-Dirac spectrum, the upper limits were found to be (5.4-7.0)×109 cm-2 for the three time windows.

Published
2021

15. Antineutrino Energy Spectrum Unfolding Based on the Daya Bay Measurement and Its Applications

Author

collaboration, Daya Bay, An, FP, Balantekin, AB, Band, HR, Bishai, M, Blyth, S, Cao, GF, Cao, J, Chang, JF, Chang, Y, Chen, HS, Chen, SM, Chen, Y, Chen, YX, Cheng, J, Cheng, ZK, Cherwinka, JJ, Chu, MC, Cummings, JP, Dalager, O, Deng, FS, Ding, YY, Diwan, MV, Dohnal, T, Dove, J, Dvorak, M, Dwyer, DA, Gallo, JP, Gonchar, M, Gong, GH, Gong, H, Gu, WQ, Guo, JY, Guo, L, Guo, XH, Guo, YH, Guo, Z, Hackenburg, RW, Hans, S, He, M, Heeger, KM, Heng, YK, Higuera, A, Hor, YK, Hsiung, YB, Hu, BZ, Hu, JR, Hu, T, Hu, ZJ, Huang, HX, Huang, XT, Huang, YB, Huber, P, Jaffe, DE, Jen, KL, Ji, XL, Ji, XP, Johnson, RA, Jones, D, Kang, L, Kettell, SH, Kohn, S, Kramer, M, Langford, TJ, Lee, J, Lee, JHC, Lei, RT, Leitner, R, Leung, JKC, Li, F, Li, JJ, Li, QJ, Li, S, Li, SC, Li, WD, Li, XN, Li, XQ, Li, YF, Li, ZB, Liang, H, Lin, CJ, Lin, GL, Lin, S, Ling, JJ, Link, JM, Littenberg, L, Littlejohn, BR, Liu, JC, Liu, JL, Lu, C, Lu, HQ, Lu, JS, Luk, KB, Ma, XB, Ma, XY, Ma, YQ, Marshall, C, Caicedo, DA Martinez, McDonald, KT, and McKeown, RD

Subjects
hep-ex, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Nuclear & Particles Physics, Atomic, molecular and optical physics, Particle and high energy physics
Abstract

The prediction of reactor antineutrino spectra will play a crucial role asreactor experiments enter the precision era. The positron energy spectrum of3.5 million antineutrino inverse beta decay reactions observed by the Daya Bayexperiment, in combination with the fission rates of fissile isotopes in thereactor, is used to extract the positron energy spectra resulting from thefission of specific isotopes. This information can be used to produce aprecise, data-based prediction of the antineutrino energy spectrum in otherreactor antineutrino experiments with different fission fractions than DayaBay. The positron energy spectra are unfolded to obtain the antineutrino energyspectra by removing the contribution from detector response with the Wiener-SVDunfolding method. Consistent results are obtained with other unfolding methods.A technique to construct a data-based prediction of the reactor antineutrinoenergy spectrum is proposed and investigated. Given the reactor fissionfractions, the technique can predict the energy spectrum to a 2% precision. Inaddition, we illustrate how to perform a rigorous comparison between theunfolded antineutrino spectrum and a theoretical model prediction that avoidsthe input model bias of the unfolding method.

Published
2021

16. A high precision calibration of the nonlinear energy response at Daya Bay

Author

Adey, D, An, FP, Balantekin, AB, Band, HR, Bishai, M, Blyth, S, Cao, D, Cao, GF, Cao, J, Chang, JF, Chang, Y, Chen, HS, Chen, SM, Chen, Y, Chen, YX, Cheng, J, Cheng, ZK, Cherwinka, JJ, Chu, MC, Chukanov, A, Cummings, JP, Dash, N, Deng, FS, Ding, YY, Diwan, MV, Dohnal, T, Dove, J, Dvořák, M, Dwyer, DA, Gonchar, M, Gong, GH, Gong, H, Gu, WQ, Guo, JY, Guo, L, Guo, XH, Guo, YH, Guo, Z, Hackenburg, RW, Hans, S, He, M, Heeger, KM, Heng, YK, Higuera, A, Hor, YK, Hsiung, YB, Hu, BZ, Hu, JR, Hu, T, Hu, ZJ, Huang, HX, Huang, XT, Huang, YB, Huber, P, Jaffe, DE, Jen, KL, Jetter, S, Ji, XL, Ji, XP, Johnson, RA, Jones, D, Kang, L, Kettell, SH, Koerner, LW, Kohn, S, Kramer, M, Langford, TJ, Lebanowski, L, Lee, J, Lee, JHC, Lei, RT, Leitner, R, Leung, JKC, Li, C, Li, F, Li, HL, Li, QJ, Li, S, Li, SC, Li, SJ, Li, WD, Li, XN, Li, XQ, Li, YF, Li, ZB, Liang, H, Lin, CJ, Lin, GL, Lin, S, Lin, SK, Ling, JJ, Link, JM, Littenberg, L, Littlejohn, BR, Liu, JC, Liu, JL, Liu, Y, Liu, YH, Lu, C, and Lu, HQ

Subjects
Nuclear and Plasma Physics, Particle and High Energy Physics, Synchrotrons and Accelerators, Physical Sciences, Affordable and Clean Energy, Neutrino, Liquid scintillator, Energy calibration, Daya Bay, physics.ins-det, Astronomical and Space Sciences, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Other Physical Sciences, Nuclear & Particles Physics, Nuclear and plasma physics
Abstract

A high precision calibration of the nonlinearity in the energy response of the Daya Bay Reactor Neutrino Experiment's antineutrino detectors is presented in detail. The energy nonlinearity originates from the particle-dependent light yield of the scintillator and charge-dependent electronics response. The nonlinearity model is constrained by γ calibration points from deployed and naturally occurring radioactive sources, the β spectrum from 12B decays, and a direct measurement of the electronics nonlinearity with a new flash analog-to-digital converter readout system. Less than 0.5% uncertainty in the energy nonlinearity calibration is achieved for positrons of kinetic energies greater than 1 MeV.

Published
2019

17. Measurement of the cosmic ray proton spectrum from 40 GeV to 100 TeV with the DAMPE satellite.

Author

DAMPE Collaboration, An, Q, Asfandiyarov, R, Azzarello, P, Bernardini, P, Bi, XJ, Cai, MS, Chang, J, Chen, DY, Chen, HF, Chen, JL, Chen, W, Cui, MY, Cui, TS, Dai, HT, D'Amone, A, De Benedittis, A, De Mitri, I, Di Santo, M, Ding, M, Dong, TK, Dong, YF, Dong, ZX, Donvito, G, Droz, D, Duan, JL, Duan, KK, D'Urso, D, Fan, RR, Fan, YZ, Fang, F, Feng, CQ, Feng, L, Fusco, P, Gallo, V, Gan, FJ, Gao, M, Gargano, F, Gong, K, Gong, YZ, Guo, DY, Guo, JH, Guo, XL, Han, SX, Hu, YM, Huang, GS, Huang, XY, Huang, YY, Ionica, M, Jiang, W, Jin, X, Kong, J, Lei, SJ, Li, S, Li, WL, Li, X, Li, XQ, Li, Y, Liang, YF, Liang, YM, Liao, NH, Liu, CM, Liu, H, Liu, J, Liu, SB, Liu, WQ, Liu, Y, Loparco, F, Luo, CN, Ma, M, Ma, PX, Ma, SY, Ma, T, Ma, XY, Marsella, G, Mazziotta, MN, Mo, D, Niu, XY, Pan, X, Peng, WX, Peng, XY, Qiao, R, Rao, JN, Salinas, MM, Shang, GZ, Shen, WH, Shen, ZQ, Shen, ZT, Song, JX, Su, H, Su, M, Sun, ZY, Surdo, A, Teng, XJ, Tykhonov, A, Vitillo, S, Wang, C, Wang, H, Wang, HY, and Wang, JZ

Subjects
DAMPE Collaboration, astro-ph.HE
Abstract

The precise measurement of the spectrum of protons, the most abundant component of the cosmic radiation, is necessary to understand the source and acceleration of cosmic rays in the Milky Way. This work reports the measurement of the cosmic ray proton fluxes with kinetic energies from 40 GeV to 100 TeV, with 2 1/2 years of data recorded by the DArk Matter Particle Explorer (DAMPE). This is the first time that an experiment directly measures the cosmic ray protons up to ~100 TeV with high statistics. The measured spectrum confirms the spectral hardening at ~300 GeV found by previous experiments and reveals a softening at ~13.6 TeV, with the spectral index changing from ~2.60 to ~2.85. Our result suggests the existence of a new spectral feature of cosmic rays at energies lower than the so-called knee and sheds new light on the origin of Galactic cosmic rays.

Published
2019

18. Extraction of the U235 and Pu239 Antineutrino Spectra at Daya Bay

Author

Adey, D, An, FP, Balantekin, AB, Band, HR, Bishai, M, Blyth, S, Cao, D, Cao, GF, Cao, J, Chang, JF, Chang, Y, Chen, HS, Chen, SM, Chen, Y, Chen, YX, Cheng, J, Cheng, ZK, Cherwinka, JJ, Chu, MC, Chukanov, A, Cummings, JP, Dash, N, Deng, FS, Ding, YY, Diwan, MV, Dohnal, T, Dove, J, Dvořák, M, Dwyer, DA, Gonchar, M, Gong, GH, Gong, H, Gu, WQ, Guo, JY, Guo, L, Guo, XH, Guo, YH, Guo, Z, Hackenburg, RW, Hans, S, He, M, Heeger, KM, Heng, YK, Higuera, A, Hor, YK, Hsiung, YB, Hu, BZ, Hu, JR, Hu, T, Hu, ZJ, Huang, HX, Huang, XT, Huang, YB, Huber, P, Jaffe, DE, Jen, KL, Ji, XL, Ji, XP, Johnson, RA, Jones, D, Kang, L, Kettell, SH, Koerner, LW, Kohn, S, Kramer, M, Langford, TJ, Lee, J, Lee, JHC, Lei, RT, Leitner, R, Leung, JKC, Li, C, Li, F, Li, HL, Li, QJ, Li, S, Li, SC, Li, SJ, Li, WD, Li, XN, Li, XQ, Li, YF, Li, ZB, Liang, H, Lin, CJ, Lin, GL, Lin, S, Ling, JJ, Link, JM, Littenberg, L, Littlejohn, BR, Liu, JC, Liu, JL, Liu, Y, Liu, YH, Lu, C, Lu, HQ, Lu, JS, Luk, KB, and B., X

Subjects
Nuclear and Plasma Physics, Particle and High Energy Physics, Synchrotrons and Accelerators, Physical Sciences, Daya Bay Collaboration, hep-ex, physics.ins-det, Mathematical Sciences, Engineering, General Physics, Mathematical sciences, Physical sciences
Abstract

This Letter reports the first extraction of individual antineutrino spectra from ^{235}U and ^{239}Pu fission and an improved measurement of the prompt energy spectrum of reactor antineutrinos at Daya Bay. The analysis uses 3.5×10^{6} inverse beta-decay candidates in four near antineutrino detectors in 1958 days. The individual antineutrino spectra of the two dominant isotopes, ^{235}U and ^{239}Pu, are extracted using the evolution of the prompt spectrum as a function of the isotope fission fractions. In the energy window of 4-6 MeV, a 7% (9%) excess of events is observed for the ^{235}U (^{239}Pu) spectrum compared with the normalized Huber-Mueller model prediction. The significance of discrepancy is 4.0σ for ^{235}U spectral shape compared with the Huber-Mueller model prediction. The shape of the measured inverse beta-decay prompt energy spectrum disagrees with the prediction of the Huber-Mueller model at 5.3σ. In the energy range of 4-6 MeV, a maximal local discrepancy of 6.3σ is observed.

Published
2019

19. Improved measurement of the reactor antineutrino flux at Daya Bay

Author

Adey, D, An, FP, Balantekin, AB, Band, HR, Bishai, M, Blyth, S, Cao, D, Cao, GF, Cao, J, Chan, YL, Chang, JF, Chang, Y, Chen, HS, Chen, SM, Chen, Y, Chen, YX, Cheng, J, Cheng, ZK, Cherwinka, JJ, Chu, MC, Chukanov, A, Cummings, JP, Deng, FS, Ding, YY, Diwan, MV, Dolgareva, M, Dove, J, Dwyer, DA, Edwards, WR, Gonchar, M, Gong, GH, Gong, H, Gu, WQ, Guo, L, Guo, XH, Guo, YH, Guo, Z, Hackenburg, RW, Hans, S, He, M, Heeger, KM, Heng, YK, Higuera, A, Hsiung, YB, Hu, BZ, Hu, T, Hu, ZJ, Huang, HX, Huang, XT, Huang, YB, Huber, P, Huo, W, Hussain, G, Jaffe, DE, Jen, KL, Ji, XL, Ji, XP, Johnson, RA, Jones, D, Kang, L, Kettell, SH, Koerner, LW, Kohn, S, Kramer, M, Langford, TJ, Lebanowski, L, Lee, J, Lee, JHC, Lei, RT, Leitner, R, Leung, JKC, Li, C, Li, F, Li, HL, Li, QJ, Li, S, Li, SC, Li, SJ, Li, WD, Li, XN, Li, XQ, Li, YF, Li, ZB, Liang, H, Lin, CJ, Lin, GL, Lin, S, Lin, SK, Lin, YC, Ling, JJ, Link, JM, Littenberg, L, Littlejohn, BR, Liu, JC, Liu, JL, Liu, Y, Liu, YH, Loh, CW, Lu, C, and Lu, HQ

Subjects
hep-ex, physics.ins-det, Digestive Diseases
Abstract

This work reports a precise measurement of the reactor antineutrino flux using 2.2 million inverse beta decay (IBD) events collected with the Daya Bay near detectors in 1230 days. The dominant uncertainty on the neutron detection efficiency is reduced by 56% with respect to the previous measurement through a comprehensive neutron calibration and detailed data and simulation analysis. The new average IBD yield is determined to be (5.91±0.09)×10-43 cm2/fission with total uncertainty improved by 29%. The corresponding mean fission fractions from the four main fission isotopes U235, U238, Pu239, and Pu241 are 0.564, 0.076, 0.304, and 0.056, respectively. The ratio of measured to predicted antineutrino yield is found to be 0.952±0.014±0.023 (1.001±0.015±0.027) for the Huber-Mueller (ILL-Vogel) model, where the first and second uncertainty are experimental and theoretical model uncertainty, respectively. This measurement confirms the discrepancy between the world average of reactor antineutrino flux and the Huber-Mueller model.

Published
2019

20. Measurement of the cosmic ray proton spectrum from 40 GeV to 100 TeV with the DAMPE satellite

Author

Collaboration, DAMPE, An, Q, Asfandiyarov, R, Azzarello, P, Bernardini, P, Bi, XJ, Cai, MS, Chang, J, Chen, DY, Chen, HF, Chen, JL, Chen, W, Cui, MY, Cui, TS, Dai, HT, D’Amone, A, De Benedittis, A, De Mitri, I, Di Santo, M, Ding, M, Dong, TK, Dong, YF, Dong, ZX, Donvito, G, Droz, D, Duan, JL, Duan, KK, D’Urso, D, Fan, RR, Fan, YZ, Fang, F, Feng, CQ, Feng, L, Fusco, P, Gallo, V, Gan, FJ, Gao, M, Gargano, F, Gong, K, Gong, YZ, Guo, DY, Guo, JH, Guo, XL, Han, SX, Hu, YM, Huang, GS, Huang, XY, Huang, YY, Ionica, M, Jiang, W, Jin, X, Kong, J, Lei, SJ, Li, S, Li, WL, Li, X, Li, XQ, Li, Y, Liang, YF, Liang, YM, Liao, NH, Liu, CM, Liu, H, Liu, J, Liu, SB, Liu, WQ, Liu, Y, Loparco, F, Luo, CN, Ma, M, X., P, Y., S, Ma, T, Y., X, Marsella, G, Mazziotta, MN, Mo, D, Niu, XY, Pan, X, Peng, WX, Peng, XY, Qiao, R, Rao, JN, Salinas, MM, Shang, GZ, Shen, WH, Shen, ZQ, Shen, ZT, Song, JX, Su, H, Su, M, Sun, ZY, Surdo, A, Teng, XJ, Tykhonov, A, Vitillo, S, Wang, C, Wang, H, Wang, HY, and Wang, JZ

Subjects
Nuclear and Plasma Physics, Particle and High Energy Physics, Physical Sciences, DAMPE Collaboration, astro-ph.HE
Abstract

The precise measurement of the spectrum of protons, the most abundant component of the cosmic radiation, is necessary to understand the source and acceleration of cosmic rays in the Milky Way. This work reports the measurement of the cosmic ray proton fluxes with kinetic energies from 40 GeV to 100 TeV, with 2 1/2 years of data recorded by the DArk Matter Particle Explorer (DAMPE). This is the first time that an experiment directly measures the cosmic ray protons up to ~100 TeV with high statistics. The measured spectrum confirms the spectral hardening at ~300 GeV found by previous experiments and reveals a softening at ~13.6 TeV, with the spectral index changing from ~2.60 to ~2.85. Our result suggests the existence of a new spectral feature of cosmic rays at energies lower than the so-called knee and sheds new light on the origin of Galactic cosmic rays.

Published
2019

21. Extraction of the ^{235}U and ^{239}Pu Antineutrino Spectra at Daya Bay.

Author

Adey, D, An, FP, Balantekin, AB, Band, HR, Bishai, M, Blyth, S, Cao, D, Cao, GF, Cao, J, Chang, JF, Chang, Y, Chen, HS, Chen, SM, Chen, Y, Chen, YX, Cheng, J, Cheng, ZK, Cherwinka, JJ, Chu, MC, Chukanov, A, Cummings, JP, Dash, N, Deng, FS, Ding, YY, Diwan, MV, Dohnal, T, Dove, J, Dvořák, M, Dwyer, DA, Gonchar, M, Gong, GH, Gong, H, Gu, WQ, Guo, JY, Guo, L, Guo, XH, Guo, YH, Guo, Z, Hackenburg, RW, Hans, S, He, M, Heeger, KM, Heng, YK, Higuera, A, Hor, YK, Hsiung, YB, Hu, BZ, Hu, JR, Hu, T, Hu, ZJ, Huang, HX, Huang, XT, Huang, YB, Huber, P, Jaffe, DE, Jen, KL, Ji, XL, Ji, XP, Johnson, RA, Jones, D, Kang, L, Kettell, SH, Koerner, LW, Kohn, S, Kramer, M, Langford, TJ, Lee, J, Lee, JHC, Lei, RT, Leitner, R, Leung, JKC, Li, C, Li, F, Li, HL, Li, QJ, Li, S, Li, SC, Li, SJ, Li, WD, Li, XN, Li, XQ, Li, YF, Li, ZB, Liang, H, Lin, CJ, Lin, GL, Lin, S, Ling, JJ, Link, JM, Littenberg, L, Littlejohn, BR, Liu, JC, Liu, JL, Liu, Y, Liu, YH, Lu, C, Lu, HQ, Lu, JS, Luk, KB, and Ma, XB

Subjects
Daya Bay Collaboration, hep-ex, physics.ins-det, General Physics, Mathematical Sciences, Physical Sciences, Engineering
Abstract

This Letter reports the first extraction of individual antineutrino spectra from ^{235}U and ^{239}Pu fission and an improved measurement of the prompt energy spectrum of reactor antineutrinos at Daya Bay. The analysis uses 3.5×10^{6} inverse beta-decay candidates in four near antineutrino detectors in 1958 days. The individual antineutrino spectra of the two dominant isotopes, ^{235}U and ^{239}Pu, are extracted using the evolution of the prompt spectrum as a function of the isotope fission fractions. In the energy window of 4-6 MeV, a 7% (9%) excess of events is observed for the ^{235}U (^{239}Pu) spectrum compared with the normalized Huber-Mueller model prediction. The significance of discrepancy is 4.0σ for ^{235}U spectral shape compared with the Huber-Mueller model prediction. The shape of the measured inverse beta-decay prompt energy spectrum disagrees with the prediction of the Huber-Mueller model at 5.3σ. In the energy range of 4-6 MeV, a maximal local discrepancy of 6.3σ is observed.

Published
2019

22. Response to Comment on Daya Bay's definition and use of Delta(m^2_ee)

Author

Collaboration, The Day Bay, Adey, D, An, FP, Balantekin, AB, Band, HR, Bishai, M, Blyth, S, Cao, D, Cao, GF, Cao, J, Chang, JF, Chang, Y, Chen, HS, Chen, SM, Chen, Y, Chen, YX, Cheng, J, Cheng, ZK, Cherwinka, JJ, Chu, MC, Chukanov, A, Cummings, JP, Dash, N, Deng, FS, Ding, YY, Diwan, MV, Dohnal, T, Dove, J, Dvorak, M, Dwyer, DA, Gonchar, M, Gong, GH, Gong, H, Gu, WQ, Guo, JY, Guo, L, Guo, XH, Guo, YH, Guo, Z, Hackenburg, RW, Hans, S, He, M, Heeger, KM, Heng, YK, Higuera, A, Hor, YK, Hsiung, YB, Hu, BZ, Hu, JR, Hu, T, Hu, ZJ, Huang, HX, Huang, XT, Huang, YB, Huber, P, Jaffe, DE, Jen, KL, Ji, XL, Ji, XP, Johnson, RA, Jones, D, Kang, L, Kettell, SH, Koerner, LW, Kohn, S, Kramer, M, Langford, TJ, Lee, J, Lee, JHC, Lei, RT, Leitner, R, Leung, JKC, Li, C, Li, F, Li, HL, Li, QJ, Li, S, Li, SC, Li, SJ, Li, WD, Li, XN, Li, XQ, Li, YF, Li, ZB, Liang, H, Lin, CJ, Lin, GL, Lin, S, Lin, SK, Ling, JJ, Link, JM, Littenberg, L, Littlejohn, BR, Liu, JC, Liu, JL, Liu, Y, Liu, YH, Lu, C, Lu, HQ, and Lu, JS

Subjects
hep-ex
Abstract

The Daya Bay Collaboration responds to comments posted by S. Parke and R.Zukanovich Funchal regarding our use of Delta(m^2_ee).

Published
2019

23. Measurement of the Electron Antineutrino Oscillation with 1958 Days of Operation at Daya Bay

Author

Adey, D, An, FP, Balantekin, AB, Band, HR, Bishai, M, Blyth, S, Cao, D, Cao, GF, Cao, J, Chan, YL, Chang, JF, Chang, Y, Chen, HS, Chen, SM, Chen, Y, Chen, YX, Cheng, J, Cheng, ZK, Cherwinka, JJ, Chu, MC, Chukanov, A, Cummings, JP, Deng, FS, Ding, YY, Diwan, MV, Dolgareva, M, Dwyer, DA, Edwards, WR, Gonchar, M, Gong, GH, Gong, H, Gu, WQ, Guo, L, Guo, XH, Guo, YH, Guo, Z, Hackenburg, RW, Hans, S, He, M, Heeger, KM, Heng, YK, Higuera, A, Hsiung, YB, Hu, BZ, Hu, JR, Hu, T, Hu, ZJ, Huang, HX, Huang, XT, Huang, YB, Huber, P, Huo, W, Hussain, G, Jaffe, DE, Jen, KL, Ji, XL, Ji, XP, Johnson, RA, Jones, D, Kang, L, Kettell, SH, Koerner, LW, Kohn, S, Kramer, M, Langford, TJ, Lebanowski, L, Lee, J, Lee, JHC, Lei, RT, Leitner, R, Leung, JKC, Li, C, Li, F, Li, HL, Li, QJ, Li, S, Li, SC, Li, SJ, Li, WD, Li, XN, Li, XQ, Li, YF, Li, ZB, Liang, H, Lin, CJ, Lin, GL, Lin, S, Lin, SK, Lin, Y-C, Ling, JJ, Link, JM, Littenberg, L, Littlejohn, BR, Liu, JC, Liu, JL, Liu, Y, Liu, YH, Loh, CW, Lu, C, and Lu, HQ

Subjects
Nuclear and Plasma Physics, Particle and High Energy Physics, Synchrotrons and Accelerators, Physical Sciences, Daya Bay Collaboration, hep-ex, physics.ins-det, Mathematical Sciences, Engineering, General Physics, Mathematical sciences, Physical sciences
Abstract

We report a measurement of electron antineutrino oscillation from the Daya Bay Reactor Neutrino Experiment with nearly 4 million reactor ν[over ¯]_{e} inverse β decay candidates observed over 1958 days of data collection. The installation of a flash analog-to-digital converter readout system and a special calibration campaign using different source enclosures reduce uncertainties in the absolute energy calibration to less than 0.5% for visible energies larger than 2 MeV. The uncertainty in the cosmogenic ^{9}Li and ^{8}He background is reduced from 45% to 30% in the near detectors. A detailed investigation of the spent nuclear fuel history improves its uncertainty from 100% to 30%. Analysis of the relative ν[over ¯]_{e} rates and energy spectra among detectors yields sin^{2}2θ_{13}=0.0856±0.0029 and Δm_{32}^{2}=(2.471_{-0.070}^{+0.068})×10^{-3}  eV^{2} assuming the normal hierarchy, and Δm_{32}^{2}=-(2.575_{-0.070}^{+0.068})×10^{-3}  eV^{2} assuming the inverted hierarchy.

Published
2018

24. Search for a time-varying electron antineutrino signal at Daya Bay

Author

Adey, D, An, FP, Balantekin, AB, Band, HR, Bishai, M, Blyth, S, Cao, D, Cao, GF, Cao, J, Chang, JF, Chang, Y, Chen, HS, Chen, SM, Chen, Y, Chen, YX, Cheng, J, Cheng, ZK, Cherwinka, JJ, Chu, MC, Chukanov, A, Cummings, JP, Dash, N, Deng, FS, Ding, YY, Diwan, MV, Dohnal, T, Dove, J, Dvořák, M, Dwyer, DA, Gonchar, M, Gong, GH, Gong, H, Gu, WQ, Guo, JY, Guo, L, Guo, XH, Guo, YH, Guo, Z, Hackenburg, RW, Hans, S, He, M, Heeger, KM, Heng, YK, Higuera, A, Hsiung, YB, Hu, BZ, Hu, JR, Hu, T, Hu, ZJ, Huang, HX, Huang, XT, Huang, YB, Huber, P, Jaffe, DE, Jen, KL, Ji, XL, Ji, XP, Johnson, RA, Jones, D, Kang, L, Kettell, SH, Koerner, LW, Kohn, S, Kramer, M, Langford, TJ, Lau, K, Lebanowski, L, Lee, J, Lee, JHC, Lei, RT, Leitner, R, Leung, JKC, Li, C, Li, F, Li, HL, Li, QJ, Li, S, Li, SC, Li, SJ, Li, WD, Li, XN, Li, XQ, Li, YF, Li, ZB, Liang, H, Lin, CJ, Lin, GL, Lin, S, Lin, Y-C, Ling, JJ, Link, JM, Littenberg, L, Littlejohn, BR, Liu, JC, Liu, JL, Liu, Y, Liu, YH, Lu, C, Lu, HQ, and Lu, JS

Subjects
Nuclear and Plasma Physics, Particle and High Energy Physics, Physical Sciences, hep-ex, Astronomical and Space Sciences, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Quantum Physics, Nuclear & Particles Physics, Mathematical physics, Astronomical sciences, Particle and high energy physics
Abstract

A search for a time-varying νe signal was performed with 621 days of data acquired by the Daya Bay Reactor Neutrino Experiment over 704 calendar days. The time spectrum of the measured νe flux normalized to its prediction was analyzed with a Lomb-Scargle periodogram, which yielded no significant signal for periods ranging from 2 hours to nearly 2 years. The normalized time spectrum was also fit for a sidereal modulation under the Standard Model Extension (SME) framework to search for Lorentz and CPT violation (LV-CPTV). Limits were obtained for all six flavor pairs ēμ,ēτ, μτ, ēē,μμ and ττ by fitting them one at a time, constituting the first experimental constraints on the latter three. Daya Bay's high statistics and unique layout of multiple directions from three pairs of reactors to three experimental halls allowed the simultaneous constraint of individual SME LV-CPTV coefficients without assuming others contribute negligibly, a first for a neutrino experiment.

Published
2018

25. Cosmogenic neutron production at Daya Bay

Author

An, FP, Balantekin, AB, Band, HR, Bishai, M, Blyth, S, Cao, D, Cao, GF, Cao, J, Chan, YL, Chang, JF, Chang, Y, Chen, HS, Chen, SM, Chen, Y, Chen, YX, Cheng, J, Cheng, ZK, Cherwinka, JJ, Chu, MC, Chukanov, A, Cummings, JP, Ding, YY, Diwan, MV, Dolgareva, M, Dove, J, Dwyer, DA, Edwards, WR, Gill, R, Gonchar, M, Gong, GH, Gong, H, Grassi, M, Gu, WQ, Guo, L, Guo, XH, Guo, YH, Guo, Z, Hackenburg, RW, Hans, S, He, M, Heeger, KM, Heng, YK, Higuera, A, Hsiung, YB, Hu, BZ, Hu, T, Huang, HX, Huang, XT, Huang, YB, Huber, P, Huo, W, Hussain, G, Jaffe, DE, Jen, KL, Ji, XL, Ji, XP, Jiao, JB, Johnson, RA, Jones, D, Kang, L, Kettell, SH, Khan, A, Koerner, LW, Kohn, S, Kramer, M, Kwok, MW, Langford, TJ, Lau, K, Lebanowski, L, Lee, J, Lee, JHC, Lei, RT, Leitner, R, Leung, JKC, Li, C, Li, DJ, Li, F, Li, GS, Li, QJ, Li, S, Li, SC, Li, WD, Li, XN, Li, XQ, Li, YF, Li, ZB, Liang, H, Lin, CJ, Lin, GL, Lin, S, Lin, SK, Lin, Y-C, Ling, JJ, Link, JM, Littenberg, L, Littlejohn, BR, Liu, JC, Liu, JL, Loh, CW, and Lu, C

Subjects
hep-ex, physics.ins-det
Abstract

Neutrons produced by cosmic ray muons are an important background forunderground experiments studying neutrino oscillations, neutrinoless doublebeta decay, dark matter, and other rare-event signals. A measurement of theneutron yield in the three different experimental halls of the Daya Bay ReactorNeutrino Experiment at varying depth is reported. The neutron yield in DayaBay's liquid scintillator is measured to be $Y_n=(10.26\pm 0.86)\times10^{-5}$, $(10.22\pm 0.87)\times 10^{-5}$, and $(17.03\pm 1.22)\times10^{-5}~\mu^{-1}~$g$^{-1}~$cm$^2$ at depths of 250, 265, and 860meters-water-equivalent. These results are compared to other measurements andthe simulated neutron yield in Fluka and Geant4. A global fit including theDaya Bay measurements yields a power law coefficient of $0.77 \pm 0.03$ for thedependence of the neutron yield on muon energy.

Published
2018

26. Seasonal variation of the underground cosmic muon flux observed at Daya Bay

Author

An, FP, Balantekin, AB, Band, HR, Bishai, M, Blyth, S, Cao, D, Cao, GF, Cao, J, Chan, YL, Chang, JF, Chang, Y, Chen, HS, Chen, QY, Chen, SM, Chen, YX, Chen, Y, Cheng, J, Cheng, ZK, Cherwinka, JJ, Chu, MC, Chukanov, A, Cummings, JP, Ding, YY, Diwan, MV, Dolgareva, M, Dove, J, Dwyer, DA, Edwards, WR, Gill, R, Gonchar, M, Gong, GH, Gong, H, Grassi, M, Gu, WQ, Guo, L, Guo, XH, Guo, YH, Guo, Z, Hackenburg, RW, Hans, S, He, M, Heeger, KM, Heng, YK, Higuera, A, Hsiung, YB, Hu, BZ, Hu, T, Huang, EC, Huang, HX, Huang, XT, Huber, P, Huo, W, Hussain, G, Jaffe, DE, Jen, KL, Jetter, S, Ji, XP, Ji, XL, Jiao, JB, Johnson, RA, Jones, D, Kang, L, Kettell, SH, Khan, A, Kohn, S, Kramer, M, Kwan, KK, Kwok, MW, Kwok, T, Langford, TJ, Lau, K, Lebanowski, L, Lee, J, Lee, JHC, Lei, RT, Leitner, R, Li, C, Li, DJ, Li, F, Li, GS, Li, QJ, Li, S, Li, SC, Li, WD, Li, XN, Li, XQ, Li, YF, Li, ZB, Liang, H, Lin, CJ, Lin, GL, Lin, S, Lin, SK, Lin, Y-C, Ling, JJ, Link, JM, Littenberg, L, Littlejohn, BR, Liu, JL, and Liu, JC

Subjects
Particle and High Energy Physics, Physical Sciences, cosmic ray experiments, neutrino detectors, neutrino experiments, physics.ins-det, hep-ex, Astronomical and Space Sciences, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Nuclear & Particles Physics, Astronomical sciences, Particle and high energy physics
Abstract

The Daya Bay Experiment consists of eight identically designed detectors located in three underground experimental halls named as EH1, EH2, EH3, with 250, 265 and 860 meters of water equivalent vertical overburden, respectively. Cosmic muon events have been recorded over a two-year period. The underground muon rate is observed to be positively correlated with the effective atmospheric temperature and to follow a seasonal modulation pattern. The correlation coefficient α, describing how a variation in the muon rate relates to a variation in the effective atmospheric temperature, is found to be αEH1 = 0.362±0.031, αEH2 = 0.433±0.038 and αEH3 = 0.641±0.057 for each experimental hall.

Published
2018

27. Evolution of the Reactor Antineutrino Flux and Spectrum at Daya Bay

Author

An, FP, Balantekin, AB, Band, HR, Bishai, M, Blyth, S, Cao, D, Cao, GF, Cao, J, Chan, YL, Chang, JF, Chang, Y, Chen, HS, Chen, QY, Chen, SM, Chen, YX, Chen, Y, Cheng, J, Cheng, ZK, Cherwinka, JJ, Chu, MC, Chukanov, A, Cummings, JP, Ding, YY, Diwan, MV, Dolgareva, M, Dove, J, Dwyer, DA, Edwards, WR, Gill, R, Gonchar, M, Gong, GH, Gong, H, Grassi, M, Gu, WQ, Guo, L, Guo, XH, Guo, YH, Guo, Z, Hackenburg, RW, Hans, S, He, M, Heeger, KM, Heng, YK, Higuera, A, Hsiung, YB, Hu, BZ, Hu, T, Huang, EC, Huang, HX, Huang, XT, Huang, YB, Huber, P, Huo, W, Hussain, G, Jaffe, DE, Jen, KL, Ji, XP, Ji, XL, Jiao, JB, Johnson, RA, Jones, D, Kang, L, Kettell, SH, Khan, A, Kohn, S, Kramer, M, Kwan, KK, Kwok, MW, Langford, TJ, Lau, K, Lebanowski, L, Lee, J, Lee, JHC, Lei, RT, Leitner, R, Leung, JKC, Li, C, Li, DJ, Li, F, Li, GS, Li, QJ, Li, S, Li, SC, Li, WD, Li, XN, Li, XQ, Li, YF, Li, ZB, Liang, H, Lin, CJ, Lin, GL, Lin, S, Lin, SK, Lin, Y-C, Ling, JJ, Link, JM, Littenberg, L, Littlejohn, BR, Liu, JL, and Liu, JC

Subjects
Nuclear and Plasma Physics, Synchrotrons and Accelerators, Physical Sciences, Daya Bay Collaboration, hep-ex, nucl-ex, physics.ins-det, Mathematical Sciences, Engineering, General Physics, Mathematical sciences, Physical sciences
Abstract

The Daya Bay experiment has observed correlations between reactor core fuel evolution and changes in the reactor antineutrino flux and energy spectrum. Four antineutrino detectors in two experimental halls were used to identify 2.2 million inverse beta decays (IBDs) over 1230 days spanning multiple fuel cycles for each of six 2.9 GW_{th} reactor cores at the Daya Bay and Ling Ao nuclear power plants. Using detector data spanning effective ^{239}Pu fission fractions F_{239} from 0.25 to 0.35, Daya Bay measures an average IBD yield σ[over ¯]_{f} of (5.90±0.13)×10^{-43}  cm^{2}/fission and a fuel-dependent variation in the IBD yield, dσ_{f}/dF_{239}, of (-1.86±0.18)×10^{-43}  cm^{2}/fission. This observation rejects the hypothesis of a constant antineutrino flux as a function of the ^{239}Pu fission fraction at 10 standard deviations. The variation in IBD yield is found to be energy dependent, rejecting the hypothesis of a constant antineutrino energy spectrum at 5.1 standard deviations. While measurements of the evolution in the IBD spectrum show general agreement with predictions from recent reactor models, the measured evolution in total IBD yield disagrees with recent predictions at 3.1σ. This discrepancy indicates that an overall deficit in the measured flux with respect to predictions does not result from equal fractional deficits from the primary fission isotopes ^{235}U, ^{239}Pu, ^{238}U, and ^{241}Pu. Based on measured IBD yield variations, yields of (6.17±0.17) and (4.27±0.26)×10^{-43}  cm^{2}/fission have been determined for the two dominant fission parent isotopes ^{235}U and ^{239}Pu. A 7.8% discrepancy between the observed and predicted ^{235}U yields suggests that this isotope may be the primary contributor to the reactor antineutrino anomaly.

Published
2017

28. Measurement of the Reactor Antineutrino Flux and Spectrum at Daya Bay

Author

An, FP, Balantekin, AB, Band, HR, Bishai, M, Blyth, S, Butorov, I, Cao, D, Cao, GF, Cao, J, Cen, WR, Chan, YL, Chang, JF, Chang, LC, Chang, Y, Chen, HS, Chen, QY, Chen, SM, Chen, YX, Chen, Y, Cheng, JH, Cheng, J, Cheng, YP, Cherwinka, JJ, Chu, MC, Cummings, JP, de Arcos, J, Deng, ZY, Ding, XF, Ding, YY, Diwan, MV, Dove, J, Draeger, E, Dwyer, DA, Edwards, WR, Ely, SR, Gill, R, Gonchar, M, Gong, GH, Gong, H, Grassi, M, Gu, WQ, Guan, MY, Guo, L, Guo, XH, Hackenburg, RW, Han, R, Hans, S, He, M, Heeger, KM, Heng, YK, Higuera, A, Hor, YK, Hsiung, YB, Hu, BZ, Hu, LM, Hu, LJ, Hu, T, Hu, W, Huang, EC, Huang, HX, Huang, XT, Huber, P, Hussain, G, Jaffe, DE, Jaffke, P, Jen, KL, Jetter, S, Ji, XP, Ji, XL, Jiao, JB, Johnson, RA, Kang, L, Kettell, SH, Kohn, S, Kramer, M, Kwan, KK, Kwok, MW, Kwok, T, Langford, TJ, Lau, K, Lebanowski, L, Lee, J, Lei, RT, Leitner, R, Leung, KY, Leung, JKC, Lewis, CA, Li, DJ, Li, F, Li, GS, Li, QJ, Li, SC, Li, WD, Li, XN, Li, XQ, Li, YF, Li, ZB, Liang, H, Lin, CJ, and Lin, GL

Subjects
Nuclear and Plasma Physics, Particle and High Energy Physics, Synchrotrons and Accelerators, Physical Sciences, Daya Bay Collaboration, hep-ex, nucl-ex, physics.ins-det, Mathematical Sciences, Engineering, General Physics, Mathematical sciences, Physical sciences
Abstract

This Letter reports a measurement of the flux and energy spectrum of electron antineutrinos from six 2.9 GWth nuclear reactors with six detectors deployed in two near (effective baselines 512 and 561 m) and one far (1579 m) underground experimental halls in the Daya Bay experiment. Using 217 days of data, 296 721 and 41 589 inverse β decay (IBD) candidates were detected in the near and far halls, respectively. The measured IBD yield is (1.55±0.04) ×10(-18)  cm(2) GW(-1) day(-1) or (5.92±0.14) ×10(-43)  cm(2) fission(-1). This flux measurement is consistent with previous short-baseline reactor antineutrino experiments and is 0.946±0.022 (0.991±0.023) relative to the flux predicted with the Huber-Mueller (ILL-Vogel) fissile antineutrino model. The measured IBD positron energy spectrum deviates from both spectral predictions by more than 2σ over the full energy range with a local significance of up to ∼4σ between 4-6 MeV. A reactor antineutrino spectrum of IBD reactions is extracted from the measured positron energy spectrum for model-independent predictions.

Published
2016

29. New Measurement of Antineutrino Oscillation with the Full Detector Configuration at Daya Bay

Author

An, FP, Balantekin, AB, Band, HR, Bishai, M, Blyth, S, Butorov, I, Cao, GF, Cao, J, Cen, WR, Chan, YL, Chang, JF, Chang, LC, Chang, Y, Chen, HS, Chen, QY, Chen, SM, Chen, YX, Chen, Y, Cheng, JH, Cheng, J, Cheng, YP, Cherwinka, JJ, Chu, MC, Cummings, JP, de Arcos, J, Deng, ZY, Ding, XF, Ding, YY, Diwan, MV, Draeger, E, Dwyer, DA, Edwards, WR, Ely, SR, Gill, R, Gonchar, M, Gong, GH, Gong, H, Grassi, M, Gu, WQ, Guan, MY, Guo, L, Guo, XH, Hackenburg, RW, Han, R, Hans, S, He, M, Heeger, KM, Heng, YK, Higuera, A, Hor, YK, Hsiung, YB, Hu, BZ, Hu, LM, Hu, LJ, Hu, T, Hu, W, Huang, EC, Huang, HX, Huang, XT, Huber, P, Hussain, G, Jaffe, DE, Jaffke, P, Jen, KL, Jetter, S, Ji, XP, Ji, XL, Jiao, JB, Johnson, RA, Kang, L, Kettell, SH, Kramer, M, Kwan, KK, Kwok, MW, Kwok, T, Langford, TJ, Lau, K, Lebanowski, L, Lee, J, Lei, RT, Leitner, R, Leung, KY, Leung, JKC, Lewis, CA, Li, DJ, Li, F, Li, GS, Li, QJ, Li, SC, Li, WD, Li, XN, Li, XQ, Li, YF, Li, ZB, Liang, H, Lin, CJ, Lin, GL, Lin, PY, Lin, SK, and Ling, JJ

Subjects
Daya Bay Collaboration, hep-ex, nucl-ex, physics.ins-det, Mathematical Sciences, Physical Sciences, Engineering, General Physics
Abstract

We report a new measurement of electron antineutrino disappearance using the fully constructed Daya Bay Reactor Neutrino Experiment. The final two of eight antineutrino detectors were installed in the summer of 2012. Including the 404 days of data collected from October 2012 to November 2013 resulted in a total exposure of 6.9×10^{5} GW_{th}  ton days, a 3.6 times increase over our previous results. Improvements in energy calibration limited variations between detectors to 0.2%. Removal of six ^{241}Am-^{13}C radioactive calibration sources reduced the background by a factor of 2 for the detectors in the experimental hall furthest from the reactors. Direct prediction of the antineutrino signal in the far detectors based on the measurements in the near detectors explicitly minimized the dependence of the measurement on models of reactor antineutrino emission. The uncertainties in our estimates of sin^{2}2θ_{13} and |Δm_{ee}^{2}| were halved as a result of these improvements. An analysis of the relative antineutrino rates and energy spectra between detectors gave sin^{2}2θ_{13}=0.084±0.005 and |Δm_{ee}^{2}|=(2.42±0.11)×10^{-3}  eV^{2} in the three-neutrino framework.

Published
2015

30. Independent measurement of the neutrino mixing angle theta(13) via neutron capture on hydrogen at Daya Bay

Author

An, FP, Balantekin, AB, Band, HR, Beriguete, W, Bishai, M, Blyth, S, Butorov, I, Cao, GF, Cao, J, Chan, YL, Chang, JF, Chang, LC, Chang, Y, Chasman, C, Chen, H, Chen, QY, Chen, SM, Chen, X, Chen, YX, Chen, Y, Cheng, YP, Cherwinka, JJ, Chu, MC, Cummings, JP, de Arcos, J, Deng, ZY, Ding, YY, Diwan, MV, Draeger, E, Du, XF, Dwyer, DA, Edwards, WR, Ely, SR, Fu, JY, Ge, LQ, Gill, R, Gonchar, M, Gong, GH, Gong, H, Gu, WQ, Guan, MY, Guo, XH, Hackenburg, RW, Han, GH, Hans, S, He, M, Heeger, M, Heng, YK, Hinrichs, P, Hor, YK, Hsiung, YB, Hu, BZ, Hu, LM, Hu, LJ, Hu, T, Hu, W, Huang, EC, Huang, H, Huang, XT, Huber, P, Hussain, G, Isvan, Z, Jaffe, DE, Jaffke, P, Jen, KL, Jetter, S, Ji, XP, Ji, XL, Jiang, HJ, Jiao, JB, Johnson, RA, Kang, L, Kettell, SH, Kramer, M, Kwan, KK, Kwok, MW, Kwok, T, Lai, WC, Lau, K, Lebanowski, L, Lee, J, Lei, RT, Leitner, R, Leung, A, Leung, JKC, Lewis, CA, Li, DJ, Li, F, Li, GS, Li, QJ, Li, WD, Li, XN, Li, XQ, Li, YF, Li, ZB, Liang, H, Lin, CJ, Lin, GL, and Lin, PY

Subjects
hep-ex, physics.ins-det, Astronomical and Space Sciences, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Quantum Physics, Nuclear & Particles Physics
Abstract

A new measurement of the $\theta_{13}$ mixing angle has been obtained at theDaya Bay Reactor Neutrino Experiment via the detection of inverse beta decaystagged by neutron capture on hydrogen. The antineutrino events for hydrogencapture are distinct from those for gadolinium capture with largely differentsystematic uncertainties, allowing a determination independent of thegadolinium-capture result and an improvement on the precision of $\theta_{13}$measurement. With a 217-day antineutrino data set obtained with sixantineutrino detectors and from six 2.9 GW$_{th}$ reactors, the rate deficitobserved at the far hall is interpreted as $\sin^22\theta_{13}=0.083\pm0.018$in the three-flavor oscillation model. When combined with thegadolinium-capture result from Daya Bay, we obtain$\sin^22\theta_{13}=0.089\pm0.008$ as the final result for thesix-antineutrino-detector configuration of the Daya Bay experiment.

Published
2014

31. Independent measurement of the neutrino mixing angle θ13 via neutron capture on hydrogen at Daya Bay

Author

An, FP, Balantekin, AB, Band, HR, Beriguete, W, Bishai, M, Blyth, S, Butorov, I, Cao, GF, Cao, J, Chan, YL, Chang, JF, Chang, LC, Chang, Y, Chasman, C, Chen, H, Chen, QY, Chen, SM, Chen, X, Chen, YX, Chen, Y, Cheng, YP, Cherwinka, JJ, Chu, MC, Cummings, JP, de Arcos, J, Deng, ZY, Ding, YY, Diwan, MV, Draeger, E, Du, XF, Dwyer, DA, Edwards, WR, Ely, SR, Fu, JY, Ge, LQ, Gill, R, Gonchar, M, Gong, GH, Gong, H, Gu, WQ, Guan, MY, Guo, XH, Hackenburg, RW, Han, GH, Hans, S, He, M, Heeger, KM, Heng, YK, Hinrichs, P, Hor, YK, Hsiung, YB, Hu, BZ, Hu, LM, Hu, LJ, Hu, T, Hu, W, Huang, EC, Huang, H, Huang, XT, Huber, P, Hussain, G, Isvan, Z, Jaffe, DE, Jaffke, P, Jen, KL, Jetter, S, Ji, XP, Ji, XL, Jiang, HJ, Jiao, JB, Johnson, RA, Kang, L, Kettell, SH, Kramer, M, Kwan, KK, Kwok, MW, Kwok, T, Lai, WC, Lau, K, Lebanowski, L, Lee, J, Lei, RT, Leitner, R, Leung, A, Leung, JKC, Lewis, CA, Li, DJ, Li, F, Li, GS, Li, QJ, Li, WD, Li, XN, Li, XQ, Li, YF, Li, ZB, Liang, H, Lin, CJ, Lin, GL, and Lin, PY

Subjects
hep-ex, physics.ins-det, Astronomical and Space Sciences, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Quantum Physics, Nuclear & Particles Physics
Abstract

A new measurement of the $\theta_{13}$ mixing angle has been obtained at theDaya Bay Reactor Neutrino Experiment via the detection of inverse beta decaystagged by neutron capture on hydrogen. The antineutrino events for hydrogencapture are distinct from those for gadolinium capture with largely differentsystematic uncertainties, allowing a determination independent of thegadolinium-capture result and an improvement on the precision of $\theta_{13}$measurement. With a 217-day antineutrino data set obtained with sixantineutrino detectors and from six 2.9 GW$_{th}$ reactors, the rate deficitobserved at the far hall is interpreted as $\sin^22\theta_{13}=0.083\pm0.018$in the three-flavor oscillation model. When combined with thegadolinium-capture result from Daya Bay, we obtain$\sin^22\theta_{13}=0.089\pm0.008$ as the final result for thesix-antineutrino-detector configuration of the Daya Bay experiment.

Published
2014

32. Search for a light sterile neutrino at Daya Bay.

Author

An, FP, Balantekin, AB, Band, HR, Beriguete, W, Bishai, M, Blyth, S, Butorov, I, Cao, GF, Cao, J, Chan, YL, Chang, JF, Chang, LC, Chang, Y, Chasman, C, Chen, H, Chen, QY, Chen, SM, Chen, X, Chen, YX, Chen, Y, Cheng, YP, Cherwinka, JJ, Chu, MC, Cummings, JP, de Arcos, J, Deng, ZY, Ding, YY, Diwan, MV, Draeger, E, Du, XF, Dwyer, DA, Edwards, WR, Ely, SR, Fu, JY, Ge, LQ, Gill, R, Gonchar, M, Gong, GH, Gong, H, Grassi, M, Gu, WQ, Guan, MY, Guo, XH, Hackenburg, RW, Han, GH, Hans, S, He, M, Heeger, KM, Heng, YK, Hinrichs, P, Hor, YK, Hsiung, YB, Hu, BZ, Hu, LM, Hu, LJ, Hu, T, Hu, W, Huang, EC, Huang, H, Huang, XT, Huber, P, Hussain, G, Isvan, Z, Jaffe, DE, Jaffke, P, Jen, KL, Jetter, S, Ji, XP, Ji, XL, Jiang, HJ, Jiao, JB, Johnson, RA, Kang, L, Kettell, SH, Kramer, M, Kwan, KK, Kwok, MW, Kwok, T, Lai, WC, Lau, K, Lebanowski, L, Lee, J, Lei, RT, Leitner, R, Leung, A, Leung, JKC, Lewis, CA, Li, DJ, Li, F, Li, GS, Li, QJ, Li, WD, Li, XN, Li, XQ, Li, YF, Li, ZB, Liang, H, Lin, CJ, and Lin, GL

Subjects
Daya Bay Collaboration, hep-ex, Mathematical Sciences, Physical Sciences, Engineering, General Physics
Abstract

A search for light sterile neutrino mixing was performed with the first 217 days of data from the Daya Bay Reactor Antineutrino Experiment. The experiment's unique configuration of multiple baselines from six 2.9 GW(th) nuclear reactors to six antineutrino detectors deployed in two near (effective baselines 512 m and 561 m) and one far (1579 m) underground experimental halls makes it possible to test for oscillations to a fourth (sterile) neutrino in the 10(-3) eV(2)

Published
2014

33. Spectral measurement of electron antineutrino oscillation amplitude and frequency at Daya Bay.

Author

An, FP, Balantekin, AB, Band, HR, Beriguete, W, Bishai, M, Blyth, S, Brown, RL, Butorov, I, Cao, GF, Cao, J, Carr, R, Chan, YL, Chang, JF, Chang, Y, Chasman, C, Chen, HS, Chen, HY, Chen, SJ, Chen, SM, Chen, XC, Chen, XH, Chen, Y, Chen, YX, Cheng, YP, Cherwinka, JJ, Chu, MC, Cummings, JP, de Arcos, J, Deng, ZY, Ding, YY, Diwan, MV, Draeger, E, Du, XF, Dwyer, DA, Edwards, WR, Ely, SR, Fu, JY, Ge, LQ, Gill, R, Gonchar, M, Gong, GH, Gong, H, Gornushkin, YA, Gu, WQ, Guan, MY, Guo, XH, Hackenburg, RW, Hahn, RL, Han, GH, Hans, S, He, M, Heeger, KM, Heng, YK, Hinrichs, P, Hor, Yk, Hsiung, YB, Hu, BZ, Hu, LJ, Hu, LM, Hu, T, Hu, W, Huang, EC, Huang, HX, Huang, HZ, Huang, XT, Huber, P, Hussain, G, Isvan, Z, Jaffe, DE, Jaffke, P, Jetter, S, Ji, XL, Ji, XP, Jiang, HJ, Jiao, JB, Johnson, RA, Kang, L, Kettell, SH, Kramer, M, Kwan, KK, Kwok, MW, Kwok, T, Lai, WC, Lai, WH, Lau, K, Lebanowski, L, Lee, J, Lei, RT, Leitner, R, Leung, A, Leung, JKC, Lewis, CA, Li, DJ, Li, F, Li, GS, Li, QJ, Li, WD, Li, XN, Li, XQ, and Li, YF

Subjects
Daya Bay Collaboration, hep-ex, nucl-ex, General Physics, Mathematical Sciences, Physical Sciences, Engineering
Abstract

A measurement of the energy dependence of antineutrino disappearance at the Daya Bay reactor neutrino experiment is reported. Electron antineutrinos (ν¯(e)) from six 2.9  GW(th) reactors were detected with six detectors deployed in two near (effective baselines 512 and 561 m) and one far (1579 m) underground experimental halls. Using 217 days of data, 41 589 (203 809 and 92 912) antineutrino candidates were detected in the far hall (near halls). An improved measurement of the oscillation amplitude sin(2)2θ(13)=0.090(-0.009)(+0.008) and the first direct measurement of the ν¯(e) mass-squared difference |Δm(ee)2|=(2.59(-0.20)(+0.19))×10(-3)  eV2 is obtained using the observed ν¯(e) rates and energy spectra in a three-neutrino framework. This value of |Δm(ee)2| is consistent with |Δm(μμ)2| measured by muon neutrino disappearance, supporting the three-flavor oscillation model.

Published
2014

34. Results from the Daya Bay Reactor Neutrino Experiment

Author

Tsang, KV, An, FP, An, Q, Bai, JZ, Balantekin, AB, Band, HR, Beriguete, W, Bishai, M, Blyth, S, Brown, RL, Cao, GF, Cao, J, Carr, R, Chan, WT, Chang, JF, Chang, Y, Chasman, C, Chen, HS, Chen, HY, Chen, SJ, Chen, SM, Chen, XC, Chen, XH, Chen, XS, Chen, Y, Chen, YX, Cherwinka, JJ, Chu, MC, Cummings, JP, Deng, ZY, Ding, YY, Diwan, MV, Draeger, E, Du, XF, Dwyer, D, Edwards, WR, Ely, SR, Fang, SD, Fu, JY, Fu, ZW, Ge, LQ, Gill, RL, Gonchar, M, Gong, GH, Gong, H, Gornushkin, YA, Gu, WQ, Guan, MY, Guo, XH, Hackenburg, RW, Hahn, RL, Hans, S, Hao, HF, He, M, He, Q, Heeger, KM, Heng, YK, Hinrichs, P, Hor, YK, Hsiung, YB, Hu, BZ, Hu, T, Huang, HX, Huang, HZ, Huang, XT, Huber, P, Issakov, V, Isvan, Z, Jaffe, DE, Jetter, S, Ji, XL, Ji, XP, Jiang, HJ, Jiao, JB, Johnson, RA, Kang, L, Kettell, SH, Kramer, M, Kwan, KK, Kwok, MW, Kwok, T, Lai, CY, Lai, WC, Lai, WH, Lau, K, Lebanowski, L, Lee, J, Lei, RT, Leitner, R, Leung, JKC, Leung, KY, Lewis, CA, Li, F, Li, GS, Li, QJ, Li, WD, Li, XB, Li, XN, Li, XQ, and Li, Y

Subjects
Neutrino Oscillation, Neutrino Mixing, Reactor, Daya Bay
Abstract

The Daya Bay Reactor Neutrino Experiment was designed to achieve a sensitivity on the value of sin22θ13 to better than 0.01 at 90% CL. The experiment consists of eight antineutrino detectors installed underground at different baselines from six nuclear reactors. With data collected with six antineutrino detectors for 55 days, Daya Bay announced the discovery of a non-zero value for sin22θ13 with a significance of 5.2 standard deviations in March 2012. The most recent analysis with 139 days of data acquired in a six-detector configuration yields sin22θ13=0.089±0.010(stat.)±0.005(syst.), which is the most precise measurement of sin22θ13 to date. © 2013.

Published
2014

35. Improved measurement of electron antineutrino disappearance at Daya Bay

Author

An, FP, An, Q, Bai, JZ, Balantekin, AB, Band, HR, Beriguete, W, Bishai, M, Blyth, S, Brown, RL, Cao, GF, Cao, J, Carr, R, Chan, WT, Chang, JF, Chang, Y, Chasman, C, Chen, HS, Chen, HY, Chen, SJ, Chen, SM, Chen, XC, Chen, XH, Chen, XS, Chen, Y, Chen, YX, Cherwinka, JJ, Chu, MC, Cummings, JP, Deng, ZY, Ding, YY, Diwan, MV, Draeger, E, Du, XF, Dwyer, D, Edwards, WR, Ely, SR, Fang, SD, Fu, JY, Fu, ZW, Ge, LQ, Gill, RL, Gonchar, M, Gong, GH, Gong, H, Gornushkin, YA, Gu, WQ, Guan, MY, Guo, XH, Hackenburg, RW, Hahn, RL, Hans, S, Hao, HF, He, M, He, Q, Heeger, KM, Heng, YK, Hinrichs, P, Hor, YK, Hsiung, YB, Hu, BZ, Hu, T, Huang, HX, Huang, HZ, Huang, XT, Huber, P, Issakov, V, Isvan, Z, Jaffe, DE, Jetter, S, Ji, XL, Ji, XP, Jiang, HJ, Jiao, JB, Johnson, RA, Kang, L, Kettell, SH, Kramer, M, Kwan, KK, Kwok, MW, Kwok, T, Lai, CY, Lai, WC, Lai, WH, Lau, K, Lebanowski, L, Lee, J, Lei, RT, Leitner, R, Leung, JKC, Leung, KY, Lewis, CA, Li, F, Li, GS, Li, QJ, Li, WD, Li, XB, Li, XN, Li, XQ, Li, Y, and Li, ZB

Subjects
Nuclear and Plasma Physics, Particle and High Energy Physics, Physical Sciences, neutrino oscillation, neutrino mixing, reactor, Daya Bay, hep-ex, nucl-ex, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Nuclear & Particles Physics, Atomic, molecular and optical physics, Particle and high energy physics
Abstract

We report an improved measurement of the neutrino mixing angle θ13 from the Daya Bay Reactor Neutrino Experiment. We exclude a zero value for sin22θ13 with a significance of 7.7 standard deviations. Electron antineutrinos from six reactors of 2.9 GW th were detected in six antineutrino detectors deployed in two near (flux-weighted baselines of 470 m and 576 m) and one far (1648 m) underground experimental halls. Using 139 days of data, 28909 (205308) electron antineutrino candidates were detected at the far hall (near halls). The ratio of the observed to the expected number of antineutrinos assuming no oscillations at the far hall is 0.944±0.007(stat.)±0.003(syst.). An analysis of the relative rates in six detectors finds sin22θ13=0. 089±0.010(stat.)±0.005(syst.) in a three-neutrino framework. © 2013 Chinese Physical Society and the Institute of High Energy Physics of the Chinese Academy of Sciences and the Institute of Modern Physics of the Chinese Academy of Sciences and IOP Publishing Ltd.

Published
2013

37. Radiative decay of the ψ(2S) into two pseudoscalar mesons

Author

Bai, JZ, Ban, Y, Bian, JG, Blum, I, Chen, AD, Chen, GP, Chen, HF, Chen, HS, Chen, J, Chen, JC, Chen, XD, Chen, Y, Chen, YB, Cheng, BS, Choi, JB, Cui, XZ, Ding, HL, Dong, LY, Du, ZZ, Dunwoodie, W, Gao, CS, Gao, ML, Gao, SQ, Gratton, P, Gu, JH, Gu, SD, Gu, WX, Guo, YN, Guo, ZJ, Han, SW, Han, Y, Harris, FA, He, J, He, JT, He, KL, He, M, Heng, YK, Hitlin, DG, Hu, GY, Hu, HM, Hu, JL, Hu, QH, Hu, T, Huang, GS, Huang, XP, Huang, YZ, Izen, JM, Jiang, CH, Jin, Y, Jones, BD, Ju, X, Kang, JS, Ke, ZJ, Kelsey, MH, Kim, BK, Kim, HJ, Kim, SK, Kim, TY, Kong, D, Lai, YF, Lang, PF, Lankford, A, Li, CG, Li, D, Li, HB, Li, J, Li, JC, Li, PQ, Li, W, Li, WG, Li, XH, Li, XN, Li, XQ, Li, ZC, Liu, B, Liu, F, Liu, Feng, Liu, HM, Liu, J, Liu, JP, Liu, RG, Liu, Y, Liu, ZX, Lou, XC, Lowery, B, Lu, GR, Lu, F, Lu, JG, Luo, XL, C., E, M., J, Malchow, R, Mao, HS, Mao, ZP, Meng, XC, Mo, XH, Nie, J, Olsen, SL, Oyang, J, and Paluselli, D

Subjects
Nuclear and Plasma Physics, Particle and High Energy Physics, Physical Sciences, Astronomical and Space Sciences, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Quantum Physics, Nuclear & Particles Physics, Mathematical physics, Astronomical sciences, Particle and high energy physics
Abstract

Radiative decays of the radially excited charmonium resonance, (Formula presented) into (Formula presented) (Formula presented) and (Formula presented) final states have been measured in a sample of (Formula presented) (Formula presented) events collected by the BES Collaboration. The branching ratios (Formula presented) and (Formula presented) are obtained. When compared to the corresponding radiative (Formula presented) decays, the observed (Formula presented) radiative decay rates into (Formula presented) and (Formula presented) are consistent with the prediction of the “12%” rule. © 2003 The American Physical Society.

Published
2003

38. Radiative decay of the [Formula Presented] into two pseudoscalar mesons

Author

Bai, JZ, Ban, Y, Bian, JG, Blum, I, Chen, AD, Chen, GP, Chen, HF, Chen, HS, Chen, J, Chen, JC, Chen, XD, Chen, Y, Chen, YB, Cheng, BS, Choi, JB, Cui, XZ, Ding, HL, Dong, LY, Du, ZZ, Dunwoodie, W, Gao, CS, Gao, ML, Gao, SQ, Gratton, P, Gu, JH, Gu, SD, Gu, WX, Guo, YN, Guo, ZJ, Han, SW, Han, Y, Harris, FA, He, J, He, JT, He, KL, He, M, Heng, YK, Hitlin, DG, Hu, GY, Hu, HM, Hu, JL, Hu, QH, Hu, T, Huang, GS, Huang, XP, Huang, YZ, Izen, JM, Jiang, CH, Jin, Y, Jones, BD, Ju, X, Kang, JS, Ke, ZJ, Kelsey, MH, Kim, BK, Kim, HJ, Kim, SK, Kim, TY, Kong, D, Lai, YF, Lang, PF, Lankford, A, Li, CG, Li, D, Li, HB, Li, J, Li, JC, Li, PQ, Li, W, Li, WG, Li, XH, Li, XN, Li, XQ, Li, ZC, Liu, B, Liu, F, Liu, HM, Liu, J, Liu, JP, Liu, RG, Liu, Y, Liu, ZX, Lou, XC, Lowery, B, Lu, GR, Lu, F, Lu, JG, Luo, XL, Ma, EC, Ma, JM, Malchow, R, Mao, HS, Mao, ZP, Meng, XC, Mo, XH, Nie, J, Olsen, SL, Oyang, J, and Paluselli, D

Subjects
Nuclear & Particles Physics, Astronomical and Space Sciences, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Quantum Physics, Atomic, Molecular, Nuclear, Particle and Plasma Physics
Abstract

Radiative decays of the radially excited charmonium resonance, (Formula presented) into (Formula presented) (Formula presented) and (Formula presented) final states have been measured in a sample of (Formula presented) (Formula presented) events collected by the BES Collaboration. The branching ratios (Formula presented) and (Formula presented) are obtained. When compared to the corresponding radiative (Formula presented) decays, the observed (Formula presented) radiative decay rates into (Formula presented) and (Formula presented) are consistent with the prediction of the “12%” rule. © 2003 The American Physical Society.

Published
2003

39. First measurement of the branching fraction of the decay ψ(2S)→τ+τ-

Author

Bai, JZ, Ban, Y, Bian, JG, Blum, I, Chen, AD, Chen, HF, Chen, HS, Chen, J, Chen, JC, Chen, XD, Chen, Y, Chen, YB, Cheng, BS, Chi, SP, Chu, YP, Choi, JB, Cui, XZ, Dai, YS, Dong, LY, Du, ZZ, Dunwoodie, W, Fu, HY, Fu, LP, Gao, CS, Gratton, P, Gu, SD, Gu, YF, Guo, YN, Guo, ZJ, Han, SW, Han, Y, Harris, FA, He, J, He, JT, He, KL, He, M, He, X, Hong, T, Heng, YK, Hitlin, DG, Hu, GY, Hu, HM, Hu, QH, Hu, T, Huang, GS, Huang, XP, Huang, YZ, Izen, JM, Ji, XB, Jiang, CH, Jin, Y, Jones, BD, Kang, JS, Ke, ZJ, Kelsey, MH, Kim, BK, Kim, HJ, Kim, SK, Kim, TY, Kong, D, Lai, YF, Lankford, A, Li, D, Li, HB, Li, HH, Li, J, Li, JC, Li, PQ, Li, QJ, Li, RY, Li, W, Li, WG, Li, XN, Li, XQ, Liu, B, Liu, F, Liu, Feng, Liu, HM, Liu, J, Liu, JP, Liu, TR, Liu, RG, Liu, Y, Liu, ZX, Lou, XC, Lowery, B, Lu, GR, Lu, F, Lu, JG, Lu, ZJ, Luo, XL, C., E, M., J, Malchow, R, Mao, HS, Mao, ZP, Meng, XC, Mo, XH, Nie, J, and Nie, ZD

Subjects
Nuclear and Plasma Physics, Particle and High Energy Physics, Physical Sciences, Astronomical and Space Sciences, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Quantum Physics, Nuclear & Particles Physics, Mathematical physics, Astronomical sciences, Particle and high energy physics
Abstract

The branching fraction of the ψ(2S) decay into τ+τ - has been measured for the first time using the BES detector at the Beijing Electron-Positron Collider. The result is Bττ=(2.710. 43±0.55)× 10-3, where the first error is statistical and the second is systematic. This value, along with those for the branching fractions into e+e- and μ+ μ- of this resonance, satisfy well the relation predicted by the sequential lepton hypothesis. Combining all these values with the leptonic width of the resonance, the total width of the ψ(25) is determined to be (252±37) keV. ©2002 The American Physical Society.

Published
2002

40. Influence of social interaction on the purchase behavior of social commerce consumers

Author

Li Xq, Ren Dashuai, and Jie Zhen

Subjects
020204 information systems, 0502 economics and business, 05 social sciences, 0202 electrical engineering, electronic engineering, information engineering, 050211 marketing, Advertising, 02 engineering and technology, Business, General Business, Management and Accounting, Social commerce, Social relation
Abstract

BACKGROUND: Compared with traditional e-commerce, a significant feature of social commerce is the more complex network of social relations built by the user through frequent online interaction and communication. This relationship network strengthens the impact of social interaction on its purchase behavior and highlights the necessity to study social interaction in social commerce. OBJECTIVE: This research aims to study the mechanism of social interaction on the purchase behavior of social commerce consumers based on the SOR theory. METHODS: This research uses SEM to perform hypothesis testing. The survey data of 622 consumers are used to conduct empirical tests on the hypothesis proposed in the research. RESULTS: The research results show that user-website interaction, user-seller interaction, user-user interaction, user-online friend interaction can significantly enhance users’ physical presence; user-seller interaction, user-user interaction, and user-online friend interaction can significantly enhance users’ social presence; other variables can significantly enhance users’ flow experience except for the user-seller interaction; the physical presence and social presence significantly affect users’ impulsive purchasing intention, but have no significant effect on repeat purchasing intention; the flow experience significantly affects users’ impulsive purchasing willingness and repeat purchasing willingness. CONCLUSION: By connecting social interaction theory, presence theory, flow experience theory with consumer purchase behavior, the research group provides a new lens for how social interaction influence consumers’ purchase behavior in social business platform. The social business platform can learn from the research results of this paper and formulate corresponding measures to promote its own development.

Published
2021

41. GRK2 Suppresses Hepatocellular Carcinoma Metastasis and Invasion Through Down-Regulation of Prostaglandin E Receptor 2

Author

Li N, Wu JJ, Chen TT, Li XQ, Du JJ, Shan S, Wei W, and Sun WY

Subjects
grk2, hepatocellular carcinoma, invasion, migration, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, lcsh:RC254-282
Abstract

Nan Li,* Jing-Jing Wu,* Ting-Ting Chen, Xiu-Qin Li, Jia-Jia Du, Shan Shan, Wei Wei, Wu-Yi Sun Institute of Clinical Pharmacology, Anhui Medical University, Key Laboratory of Anti-Inflammatory and Immune Medicine, Ministry of Education, Anhui Collaborative Innovation Center of Anti-Inflammatory and Immune Medicine, Hefei 230032, People’s Republic of China*These authors contributed equally to this workCorrespondence: Wu-Yi Sun; Wei WeiInstitute of Clinical Pharmacology, Anhui Medical University, Key Laboratory of Anti-Inflammatory and Immune Medicine, Ministry of Education, Anhui Collaborative Innovation Center of Anti-Inflammatory and Immune Medicine, Meishan Road, Hefei 230032, Anhui Province, People’s Republic of ChinaTel/Fax +86 551 65161206Email sunwuyi51@aliyun.com; wwei@ahmu.edu.cnBackground: Hepatocellular carcinoma (HCC) is an aggressive form of human liver cancer and the fifth most common malignancy worldwide. Novel effective treatment strategies for HCC are urgently in clinical because of its poor response to conventional therapies. G protein-coupled receptor kinases (GRKs), including GRK2 and GRK3, are known that involves in various essential cellular processes and regulates numerous signaling pathways. However, the role of GRK2/3 in invasion and metastasis of HCC still remains unclear.Materials and Methods: Immunohistochemistry, Western blot, laser confocal microscopy and qRT-PCR were used to detect the expression of GRK2/3 and EP2 in liver tissues of HCC patients and DEN-induced HCC mice. Wound healing and transwell assay were applied to measure the migration and invasion of HCC cells after transfected with GRK2 siRNA. The downstream pathway of Akt and ERK was verified by Western blot.Results: The expression of GRK2 was significantly decreased, while GRK3 was not significantly changed in HCC tissues compared with noncancerous tissues of HCC patients. Moreover, GRK2 expression was reduced during liver tumorigenesis in diethylnitrosamine-induced liver tumor model. In addition, our in vitro study showed that GRK2 expression was gradually decreased with increasing HCC cell line metastatic potential, and GRK2 knockdown significantly promoted the migration and invasion of HCC cells. Furthermore, low GRK2 expression was associated with increased expression of EP2 receptor translocation to HCC cell membrane, and the activation of Akt pathway.Conclusion: These data suggest that GRK2 inhibits HCC metastasis and invasion may be through regulating EP2 receptor translocation, and this effect appears to be mediated by Akt pathway.Keywords: GRK2, hepatocellular carcinoma, invasion, migration

Published
2020

42. Search for electron-antineutrinos associated with gravitational-wave events GW150914, GW151012, GW151226, GW170104, GW170608, GW170814, and GW170817 at Daya Bay * *Daya Bay is supported in part by the Ministry of Science and Technology of China, the U.S. Department of Energy, the Chinese Academy of Sciences, the CAS Center for Excellence in Particle Physics, the National Natural Science Foundation of China, the Guangdong provincial government, the Shenzhen municipal government, the China General Nuclear Power Group, Key Laboratory of Particle and Radiation Imaging (Tsinghua University), the Ministry of Education, Key Laboratory of Particle Physics and Particle Irradiation (Shandong University), the Ministry of Education, Shanghai Laboratory for Particle Physics and Cosmology, the Research Grants Council of the Hong Kong Special Administrative Region of China, the University Development Fund of the University of Hong Kong, the MOE program for Research of Excellence at National Taiwan University, National Chia

Author

An, FP, Balantekin, AB, Band, HR, Bishai, M, Blyth, S, Cao, GF, Cao, J, Chang, JF, Chang, Y, Chen, HS, Chen, SM, Chen, Y, Chen, YX, Cheng, J, Cheng, ZK, Cherwinka, JJ, Chu, MC, Cummings, JP, Dalager, O, Deng, FS, Ding, YY, Diwan, MV, Dohnal, T, Dove, J, Dvořák, M, Dwyer, DA, Gallo, JP, Gonchar, M, Gong, GH, Gong, H, Gu, WQ, Guo, JY, Guo, L, Guo, XH, Guo, YH, Guo, Z, Hackenburg, RW, Hans, S, He, M, Heeger, KM, Heng, YK, Higuera, A, Hor, YK, Hsiung, YB, Hu, BZ, Hu, JR, Hu, T, Hu, ZJ, Huang, HX, Huang, XT, Huang, YB, Huber, P, Jaffe, DE, Jen, KL, Ji, XL, Ji, XP, Johnson, RA, Jones, D, Kang, L, Kettell, SH, Kohn, S, Kramer, M, Langford, TJ, Lee, J, Lee, JHC, Lei, RT, Leitner, R, Leung, JKC, Li, F, Li, JJ, Li, QJ, Li, S, Li, SC, Li, WD, Li, XN, Li, XQ, Li, YF, Li, ZB, Liang, H, Lin, CJ, Lin, GL, Lin, S, Ling, JJ, Link, JM, Littenberg, L, Littlejohn, BR, Liu, JC, Liu, JL, Lu, C, Lu, HQ, Lu, JS, Luk, KB, B., X, Y., X, Q., Y, Marshall, C, Caicedo, DA Martinez, McDonald, KT, McKeown, RD, and Meng, Y

Subjects
astro-ph.HE, Particle and Plasma Physics, gravitational waves, hep-ex, fluence, Molecular, Nuclear, electron-antineutrinos, upper limit, physics.ins-det, Atomic, Nuclear & Particles Physics
Abstract

The establishment of a possible connection between neutrino emission and gravitational-wave (GW) bursts is important to our understanding of the physical processes that occur when black holes or neutron stars merge. In the Daya Bay experiment, using the data collected from December 2011 to August 2017, a search was performed for electron-Antineutrino signals that coincided with detected GW events, including GW150914, GW151012, GW151226, GW170104, GW170608, GW170814, and GW170817. We used three time windows of 10, 500, and 1000 s relative to the occurrence of the GW events and a neutrino energy range of 1.8 to 100 MeV to search for correlated neutrino candidates. The detected electron-Antineutrino candidates were consistent with the expected background rates for all the three time windows. Assuming monochromatic spectra, we found upper limits (90% confidence level) of the electron-Antineutrino fluence of (1.13-2.44)×1011 cm-2 at 5 MeV to 8.0×107 cm-2 at 100 MeV for the three time windows. Under the assumption of a Fermi-Dirac spectrum, the upper limits were found to be (5.4-7.0)×109 cm-2 for the three time windows.

Published
2021

43. Euphornin reduces proliferation of human cervical adenocarcinoma HeLa cells through induction of apoptosis and G2/M cell cycle arrest

Author

Li XQ, Bai YL, Zhang DL, Jiao HS, and He RX

Subjects
proliferation, cervical adenocarcinoma HeLa cells, apoptosis, G2/M cell cycle arrest, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Euphornin, lcsh:RC254-282
Abstract

Xiao-Qiang Li,1,* Yin-Liang Bai,1,* De-Li Zhang,1,* Hai-Sheng Jiao,1 Rong-Xia He2 1Pharmacy Department, Lanzhou University Second Hospital, Lanzhou 730030, China; 2Department of Gynecology, Lanzhou University Second Hospital, Lanzhou 730030, China *These authors contributed equally to this work Background: The plant Euphorbia helioscopia L. has been used in traditional Chinese medicine for treating various disorders such as tuberculosis and edema. The aim of this study was to investigate the effect of euphornin, a bioactive compound isolated from E. helioscopia, on proliferation of human cervical adenocarcinoma HeLa cells by analyzing cell viability, rate of apoptosis, and cell cycle progression. Materials and methods: The sulforhodamine B assay was used to study the effect of euphornin on the proliferation of HeLa cells. Morphological changes to cell nuclei were identified after Hoechst 33342 staining. Mitochondrial membrane depolarization (MMP) was analyzed after staining with JC-1 dye. The influence of euphornin on the apoptosis rate was analyzed by Annexin V/propidium iodide double staining. Fluorescence-activated cell sorting was applied to investigate the influence of euphornin on cell cycle progression. Proteins were obtained from HeLa cells and analyzed by Western blots. Results: A cell viability assay showed that euphornin inhibited proliferation of HeLa cells in a dose-dependent and time-dependent manner. Euphornin also induced apoptosis in a concentration-dependent manner, with the rates of apoptosis ranging from 25.3% to 52.6%. A high concentration of euphornin was found to block HeLa cells at the G2/M stage. A Western blot analysis suggested that euphornin might exhibit antitumor activity by inducing apoptosis. Euphornin treatment altered the ratio of Bax/Bcl-2 in HeLa cells, which led to the release of cytochrome complex. The levels of cleaved caspase-3, caspase-8, caspase-9, and caspase-10 were also markedly increased by euphornin treatment. Analysis of cell cycles indicated that euphornin induced cell cycle arrest by increasing the level of the phospho-CDK1 (Tyr15) protein. The various assays demonstrated that euphornin treatment resulted in a significant suppression of cell growth accompanied by G2/M cell cycle arrest and increased rate of apoptosis via mitochondrial and caspase pathways. Conclusion: Our findings suggest that euphornin has the potential to be used as a cancer therapeutic agent against human cervical adenocarcinoma. Keywords: euphornin, cervical adenocarcinoma HeLa cells, proliferation, apoptosis, G2/M cell cycle arrest

Published
2018

44. Proton Shell Evolution below Sn-132: First Measurement of Low-Lying beta-Emitting Isomers in Ag-123,Ag-325

Author

Chen, ZQ, Li, ZH, Hua, H, Watanabe, H, Yuan, CX, Zhang, SQ, Lorusso, G, Nishimura, S, Baba, H, Browne, F, Benzoni, G, Chae, KY, Crespi, FCL, Doornenbal, P, Fukuda, N, Gey, G, Gernhaeuser, R, Inabe, N, Isobe, T, Jiang, DX, Jungclaus, A, Jung, HS, Jin, Y, Kameda, D, Kim, GD, Kim, YK, Kojouharov, I, Kondev, FG, Kubo, T, Kurz, N, Kwon, YK, Li, XQ, Lou, JL, Lane, GJ, Li, CG, Luo, DW, Montaner-Piza, A, Moschner, K, Niu, CY, Naqvi, F, Niikura, M, Nishibata, H, Odahara, A, Orlandi, R, Patel, Z, Podolyak, Zs, Sumikama, T, Soderstrom, P-A, Sakurai, H, Schaffner, H, Simpson, GS, Steiger, K, Suzuki, H, Taprogge, J, Takeda, H, Vajta, Zs, Wang, HK, Wu, J, Wendt, A, Wang, CG, Wu, HY, Wang, X, Wu, CG, Xu, C, Xu, ZY, Yagi, A, Ye, YL, and Yoshinaga, K

Subjects
RIKEN, Science & Technology, IMPACT, Physics, Physical Sciences, Physics, Multidisciplinary, ISOTOPES, DECAY
Abstract

The β-delayed γ-ray spectroscopy of neutron-rich ^{123,125}Ag isotopes is investigated at the Radioactive Isotope Beam Factory of RIKEN, and the long-predicted 1/2^{-} β-emitting isomers in ^{123,125}Ag are identified for the first time. With the new experimental results, the systematic trend of energy spacing between the lowest 9/2^{+} and 1/2^{-} levels is extended in Ag isotopes up to N=78, providing a clear signal for the reduction of the Z=40 subshell gap in Ag towards N=82. Shell-model calculations with the state-of-the-art V_{MU} plus M3Y spin-orbit interaction give a satisfactory description of the low-lying states in ^{123,125}Ag. The tensor force is found to play a crucial role in the evolution of the size of the Z=40 subshell gap. The observed inversion of the single-particle levels around ^{123}Ag can be well interpreted in terms of the monopole shift of the π1g_{9/2} orbitals mainly caused by the increasing occupation of ν1h_{11/2} orbitals. ispartof: PHYSICAL REVIEW LETTERS vol:122 issue:21 ispartof: location:United States status: published

Published
2019

45. Measurements of the branching fractions of the singly Cabibbo-suppressed decays D-0 -> omega eta, eta(()'())pi(0) and eta(()'())eta

Author

Ablikim, M, Achasov, MN, Ahmed, S, Albayrak, O, Albrecht, M, Ambrose, DJ, Amoroso, A, An, FF, An, Q, Bai, JZ, Bakina, O, Ferroli, RB, Ban, Y, Bennett, DW, Bennett, JV, Berger, N, Bertani, M, Bettoni, D, Bian, JM, Bianchi, F, Boger, E, Boyko, I, Briere, RA, Cai, H, Cai, X, Cakir, O, Calcaterra, A, Cao, GF, Cetin, SA, Chai, J, Chang, JF, Chelkov, G, Chen, G, Chen, HS, Chen, JC, Chen, ML, Chen, PL, Chen, SJ, Chen, XR, Chen, YB, Chu, XK, Cibinetto, G, Dai, HL, Dai, JP, Dbeyssi, A, Dedovich, D, Deng, ZY, Denig, A, Denysenko, I, Destefanis, M, De Mori, F, Ding, Y, Dong, C, Dong, J, Dong, LY, Dong, MY, Dou, ZL, Du, SX, Duan, PF, Fang, J, Fang, SS, Fang, X, Fang, Y, Farinelli, R, Fava, L, Fegan, S, Feldbauer, F, Felici, G, Feng, CQ, Fioravanti, E, Fritsch, M, Fu, CD, Gao, Q, Gao, XL, Gao, Y, Gao, YG, Gao, Z, Garzia, I, Goetzen, K, Gong, L, Gong, WX, Gradl, W, Greco, M, Gu, MH, Gu, S, Gu, YT, Guo, AQ, Guo, LB, Guo, RP, Guo, YP, Haddadi, Z, Hafner, A, Han, S, Hao, XQ, Harris, FA, He, KL, He, XQ, Heinsius, FH, Held, T, Heng, YK, Holtmann, T, Hou, ZL, Hu, C, Hu, HM, Hu, T, Hu, Y, Huang, GS, Huang, JS, Huang, XT, Huang, XZ, Huang, ZL, Hussain, T, Andersson, WI, Ji, Q, Ji, QP, Ji, XB, Ji, XL, Jiang, XS, Jiang, XY, Jiao, JB, Jiao, Z, Jin, DP, Jin, S, Johansson, T, Julin, A, Kalantar-Nayestanaki, N, Kang, XL, Kang, XS, Kavatsyuk, M, Ke, BC, Khan, T, Kiese, P, Kliemt, R, Kloss, B, Kolcu, OB, Kopf, B, Kornicer, M, Kupsc, A, Kuhn, W, Lange, JS, Lara, M, Larin, P, Lavezzi, L, Leithoff, H, Leng, C, Li, C, Li, DM, Li, F, Li, FY, Li, G, Li, HB, Li, HJ, Li, JC, Li, J, Li, K, Li, L, Li, PL, Li, PR, Li, QY, Li, T, Li, WD, Li, WG, Li, XL, Li, XN, Li, XQ, Li, ZB, Liang, H, Liang, YF, Liang, YT, Liao, GR, Lin, DX, Liu, B, Liu, BJ, Liu, CX, Liu, D, Liu, FH, Liu, F, Liu, HB, Liu, HM, Liu, H, Liu, JB, Liu, JP, Liu, JY, Liu, K, Liu, KY, Liu, LD, Liu, PL, Liu, Q, Liu, SB, Liu, X, Liu, YB, Liu, ZA, Liu, Z, Loehner, H, Long, YF, Lou, XC, Lu, HJ, Lu, JG, Lu, Y, Lu, YP, Luo, CL, Luo, MX, Luo, T, Luo, XL, Lyu, XR, Ma, FC, Ma, HL, Ma, LL, Ma, MM, Ma, QM, Ma, T, Ma, XN, Ma, XY, Ma, YM, Maas, FE, Maggiora, M, Malik, QA, Mao, YJ, Mao, ZP, Marcello, S, Messchendorp, JG, Mezzadri, G, Min, J, Min, TJ, Mitchell, RE, Mo, XH, Mo, YJ, Morales, CM, Morello, G, Muchnoi, NY, Muramatsu, H, Musiol, P, Nefedov, Y, Nerling, F, Nikolaev, IB, Ning, Z, Nisar, S, Niu, SL, Niu, XY, Olsen, SL, Ouyang, Q, Pacetti, S, Pan, Y, Papenbrock, M, Patteri, P, Pelizaeus, M, Pellegrino, J, Peng, HP, Peters, K, Pettersson, J, Ping, JL, Ping, RG, Poling, R, Prasad, V, Qi, HR, Qi, M, Qian, S, Qiao, CF, Qin, JJ, Qin, N, Qin, XS, Qin, ZH, Qiu, JF, Rashid, KH, Redmer, CF, Ripka, M, Rong, G, Rosner, C, Sarantsev, A, Savrie, M, Schnier, C, Schoenning, K, Shan, W, Shao, M, Shen, CP, Shen, PX, Shen, XY, Sheng, HY, Song, JJ, Song, WM, Song, XY, Sosio, S, Spataro, S, Sun, GX, Sun, JF, Sun, SS, Sun, XH, Sun, YJ, Sun, YK, Sun, YZ, Sun, ZJ, Sun, ZT, Tang, CJ, Tang, X, Tapan, I, Thorndike, EH, Tiemens, M, Tsednee, B, Uman, I, Varner, GS, Wang, B, Wang, BL, Wang, D, Wang, DY, Wang, K, Wang, LL, Wang, LS, Wang, M, Wang, P, Wang, PL, Wang, WP, Wang, XF, Wang, Y, Wang, YD, Wang, YF, Wang, YQ, Wang, Z, Wang, ZG, Wang, ZH, Wang, ZY, Weber, T, Wei, DH, Weidenkaff, P, Wen, SP, Wiedner, U, Wolke, M, Wu, LH, Wu, LJ, Wu, Z, Xia, L, Xia, Y, Xiao, D, Xiao, H, Xiao, YJ, Xiao, ZJ, Xie, YG, Xie, YH, Xiong, XA, Xiu, QL, Xu, GF, Xu, JJ, Xu, L, Xu, QJ, Xu, QN, Xu, XP, Yan, L, Yan, WB, Yan, WC, Yan, YH, Yang, HJ, Yang, HX, Yang, L, Yang, YH, Yang, YX, Yang, Y, Ye, M, Ye, MH, Yin, JH, You, ZY, Yu, BX, Yu, CX, Yu, JS, Yuan, CZ, Yuan, Y, Yuncu, A, Zafar, AA, Zallo, A, Zeng, Y, Zeng, Z, Zhang, BX, Zhang, BY, Zhang, CC, Zhang, DH, Zhang, HH, Zhang, HY, Zhang, J, Zhang, JL, Zhang, JQ, Zhang, JW, Zhang, JY, Zhang, JZ, Zhang, K, Zhang, L, Zhang, SQ, Zhang, XY, Zhang, YH, Zhang, YT, Zhang, Y, Zhang, ZH, Zhang, ZP, Zhang, ZY, Zhao, G, Zhao, JW, Zhao, JY, Zhao, JZ, Zhao, L, Zhao, MG, Zhao, Q, Zhao, SJ, Zhao, TC, Zhao, YB, Zhao, ZG, Zhemchugov, A, Zheng, B, Zheng, JP, Zheng, WJ, Zheng, YH, Zhong, B, Zhou, L, Zhou, X, Zhou, XK, Zhou, XR, Zhou, XY, Zhou, YX, Zhu, J, Zhu, K, Zhu, KJ, Zhu, S, Zhu, SH, Zhu, XL, Zhu, YC, Zhu, YS, Zhu, ZA, Zhuang, J, Zotti, L, Zou, BS, and Zou, JH

Published
2018

47. Measurement of the absolute branching fraction of D-vertical bar -> (K)over-bar(0)e(vertical bar) nu(e) via (K)over-bar(0) -> pi(0)pi(0)

Author

Ablikim, M, Achasov, N, Ai, XC, Albayrak, O, Albrecht, M, Ambrose, DJ, Amoroso, A, An, FF, An, Q, Bai, JZ, Ferroli, RB, Ban, Y, Bennett, DW, Bennett, JV, Bertani, M, Bettonin, D, Bian, JM, Bianchi, F, Boger, E, Boyko, I, Briere, RA, Cai, H, Cai, X, Cakir, O, Caleaterra, A, Cao, GF, Cetin, SA, Chang, JF, Chelkov, G, Chen, G, Chen, HS, Chen, HY, Chen, JC, Chen, ML, Chen, S, Chen, SJ, Chen, X, Chen, XR, Chen, YB, Cheng, HP, Chu, XK, Cibinetto, G, Dai, HL, Dai, JP, Dbeyssi, A, Dedovich, D, Deng, ZY, Denig, A, Denysenko, I, Destefanis, M, De Mori, F, Ding, Y, Dong, C, Dong, J, Dong, LY, Dong, MY, Dou, ZL, Du, SX, Duan, PF, Fan, JZ, Fang, J, Fang, SS, Fang, X, Fang, Y, Farinelli, R, Fava, L, Fedorov, O, Feldbauer, F, Felici, G, Feng, CQ, Fioravanti, E, Fritsch, M, Fu, CD, Gao, Q, Gao, XL, Gao, XY, Gao, Y, Gao, Z, Garzia, I, Goetzen, K, Gong, L, Gong, WX, Gradl, W, Greco, M, Gu, MH, Gu, YT, Guan, YH, Guo, AQ, Guo, LB, Guo, RP, Guo, Y, Guo, YP, Haddadi, Z, Hafner, A, Han, S, Hao, XQ, Harris, FA, He, KL, Held, T, Heng, YK, Hou, ZL, Hu, C, Hu, HM, Hu, JF, Hu, T, Hu, Y, Huang, GS, Huang, JS, Huang, XT, Huang, XZ, Huang, Y, Huang, ZL, Hussain, T, Ji, Q, Ji, QP, Ji, XB, Ji, XL, Jiang, LW, Jiang, XS, Jiang, XY, Jiao, JB, Jiao, Z, Jin, DP, Jin, S, Johansson, T, Julin, A, Kalantar-Nayestanaki, N, Kang, XL, Kang, XS, Kavatsyuk, M, Ke, BC, Kiese, P, Kliemt, R, Kloss, B, Kolc, OB, Kopf, B, Kornicer, M, Kupse, A, Kuehn, W, Lange, JS, Lara, M, Larin, P, Leng, C, Li, C, Li, DM, Li, F, Li, FY, Li, G, Li, HB, Li, HJ, Li, JC, Li, J, Li, K, Li, L, Li, PR, Li, QY, Li, T, Li, WD, Li, WG, Li, XL, Li, XN, Li, XQ, Li, YB, Li, ZB, Liang, H, Liang, YF, Liang, YT, Liao, GR, Lin, DX, Liu, B, Liu, BJ, Liu, CX, Liu, D, Liu, FH, Liu, F, Liu, HB, Liu, HH, Liu, HM, Liu, J, Liu, JB, Liu, JP, Liu, JY, Liu, K, Liu, KY, Liu, LD, Liu, PL, Liu, Q, Liu, SB, Liu, X, Liu, YB, Liu, ZA, Liu, Z, Loehner, H, Lou, XC, Lu, HJ, Lu, JG, Lu, Y, Lu, YP, Luo, CL, Luo, MX, Luo, T, Luo, XL, Lu, XR, Ma, FC, Ma, HL, Ma, LL, Ma, MM, Ma, QM, Ma, T, Ma, XN, Ma, XY, Ma, YM, Maas, FE, Maggiora, M, Mao, YJ, Mao, ZP, Marcello, S, Messchendorp, JG, Min, J, Min, TJ, Mitchell, RE, Mo, XH, Mo, YJ, Morales, CM, Muchnoi, NY, Muramatsu, H, Nefedov, Y, Nerling, F, Nikolaev, IB, Ning, Z, Nisar, S, Niu, SL, Niu, XY, Olsen, SL, Ouyang, Q, Pacetti, S, Pan, Y, Patteri, P, Pelizaeus, M, Peng, HP, Peters, K, Pettersson, J, Ping, JL, Ping, RG, Poling, R, Prasad, V, Qi, HR, Qi, M, Qian, S, Qiao, CF, Qin, LQ, Qin, N, Qin, XS, Qin, ZH, Qiu, JF, Rashid, KH, Redmer, CF, Ripka, M, Rong, G, Rosner, C, Ruan, XD, Sarantsev, A, Savrie, M, Schoenning, K, Schumann, S, Shan, W, Shao, M, Shen, CP, Shen, PX, Shen, XY, Sheng, HY, Shi, M, Song, WM, Song, XY, Sosio, S, Spataro, S, Sun, GX, Sun, JF, Sun, SS, Sun, XH, Sun, YJ, Sun, YZ, Sun, ZJ, Sun, ZT, Tang, CJ, Tang, X, Tapan, I, Thorndike, EH, Tiemens, M, Ullrich, M, Uman, I, Varner, GS, Wang, B, Wang, BL, Wang, D, Wang, DY, Wang, K, Wang, LL, Wang, LS, Wang, M, Wang, P, Wang, PL, Wang, W, Wang, WP, Wang, XF, Wang, Y, Wang, YD, Wang, YF, Wang, YQ, Wang, Z, Wang, ZG, Wang, ZH, Wang, ZY, Weber, T, Wei, DH, Weidenkaff, P, Wen, SP, Wiedner, U, Wolke, M, Wu, LH, Wu, LJ, Wu, Z, Xia, L, Xia, Y, Xiao, D, Xiao, H, Xiao, ZJ, Xie, YG, Xiu, QL, Xu, GF, Xu, JJ, Xu, L, Xu, QJ, Xu, QN, Xu, XP, Yan, L, Yan, WB, Yan, WC, Yan, YH, Yang, HJ, Yang, HX, Yang, L, Yang, YX, Ye, M, Ye, MH, Yin, JH, Yu, BX, Yu, CX, Yu, JS, Yuan, CZ, Yuan, WL, Yuan, Y, Yuncu, A, Zafar, AA, Zallo, A, Zeng, Y, Zeng, Z, Zhang, BX, Zhang, BY, Zhang, C, Zhang, CC, Zhang, DH, Zhang, HH, Zhang, HY, Zhang, J, Zhang, JJ, Zhang, JL, Zhang, JQ, Zhang, JW, Zhang, JY, Zhang, JZ, Zhang, K, Zhang, L, Zhang, SQ, Zhang, XY, Zhang, Y, Zhang, YH, Zhang, YN, Zhang, YT, Zhang, ZH, Zhang, ZP, Zhang, ZY, Zhao, G, Zhao, JW, Zhao, JY, Zhao, JZ, Zhao, L, Zhao, MG, Zhao, Q, Zhao, QW, Zhao, SJ, Zhao, TC, Zhao, YB, Zhao, ZG, Zhemchugov, A, Zheng, B, Zheng, JP, Zheng, WJ, Zheng, YH, Zhong, B, Zhou, L, Zhou, X, Zhou, XK, Zhou, XR, Zhou, XY, Zhu, K, Zhu, KJ, Zhu, S, Zhu, SH, Zhu, XL, Zhu, YC, Zhu, YS, Zhu, ZA, Zhuangig, J, Zotti, L, Zou, BS, Zou, JH, Collaboration, BESIII, Uludağ Üniversitesi/Fen-Edebiyat Fakültesi/Fizik Bölümü., Tapan, İlhan, İstanbul Arel Üniversitesi, and [Ablikim, M. -- Ai, X. C. -- An, F. F. -- Bai, J. Z. -- Cai, X. -- Caleaterra, A. -- Cao, G. F. -- Chang, J. F. -- Chen, G. -- Chen, H. S. -- Chen, J. C. -- Chen, M. L. -- Chen, X. -- Chen, Y. B. -- Dai, H. L. -- Deng, Z. Y. -- Dong, J. -- Dong, L. Y. -- Dong, M. Y. -- Duan, P. F. -- Fang, J. -- Fang, S. S. -- Fang, Y. -- Fu, C. D. -- Gao, Q. -- Gong, W. X. -- Gu, M. H. -- Guan, Y. H. -- Guo, A. Q. -- Guo, R. P. -- Guo, Y. -- He, K. L. -- Heng, Y. K. -- Hou, Z. L. -- Hu, H. M. -- Hu, T. -- Hu, Y. -- Ji, Q. -- Ji, X. B. -- Ji, X. L. -- Jiang, X. S. -- Jin, D. P. -- Jin, S. -- Kang, X. L. -- Li, F. -- Li, G. -- Li, H. B. -- Li, H. J. -- Li, J. C. -- Li, W. D. -- Li, W. G. -- Li, X. N. -- Liu, B. J. -- Liu, C. X. -- Liu, Fang -- Liu, H. H. -- Liu, H. M. -- Liu, J. -- Liu, J. Y. -- Liu, P. L. -- Liu, Z. A. -- Lou, X. C. -- Lu, J. G. -- Lu, Y. -- Lu, Y. P. -- Luo, X. L. -- Ma, H. L. -- Ma, M. M. -- Ma, Q. M. -- Ma, T. -- Ma, X. Y. -- Mao, Z. P. -- Min, J. -- Min, T. J. -- Mo, X. H. -- Ning, Z. -- Niu, S. L. -- Niu, X. Y. -- Ouyang, Q. -- Ping, R. G. -- Prasad, V. -- Qian, S. -- Qin, X. S. -- Qin, Z. H. -- Qiu, J. F. -- Rong, G. -- Shen, X. Y. -- Sheng, H. Y. -- Shi, M. -- Song, W. M. -- Song, X. Y. -- Sun, G. X. -- Sun, S. S. -- Sun, X. H. -- Sun, Y. Z. -- Sun, Z. J. -- Tang, X. -- Wang, K. -- Wang, L. L. -- Wang, L. S. -- Wang, P. -- Wang, P. L. -- Wang, W. -- Wang, Y. F. -- Wang, Z. -- Wang, Z. G. -- Wang, Z. Y. -- Wen, S. P. -- Wu, L. H. -- Wu, L. J. -- Wu, Z. -- Xiao, H. -- Xiu, Q. L. -- Xu, G. F. -- Xu, J. J. -- Xu, L. -- Xu, Q. J. -- Yang, H. X. -- Ye, M. -- Yin, J. H. -- Yu, B. X. -- Yuan, C. Z. -- Yuan, Y. -- Zhang, B. X. -- Zhang, B. Y. -- Zhang, C. C. -- Zhang, D. H. -- Zhang, H. Y. -- Zhang, J. -- Zhang, J. J. -- Zhang, J. L. -- Zhang, J. Q. -- Zhang, J. W. -- Zhang, J. Y. -- Zhang, J. Z. -- Zhang, K. -- Zhang, L. -- Zhang, Y. -- Zhang, Y. H. -- Zhao, G. -- Zhao, J. W. -- Zhao, J. Y. -- Zhao, J. Z. -- Zhao, Ling -- Zhao, Q. -- Zhao, Q. W. -- Zhao, T. C. -- Zhao, Y. B. -- Zheng, J. P. -- Zhou, L. -- Zhou, X. Y. -- Zhu, K. -- Zhu, K. J. -- Zhu, S. -- Zhu, Y. S. -- Zhu, Z. A. -- Zhuangig, J. -- Zou, B. S. -- Zou, J. H.] Inst High Energy Phys, Beijing 100049, Peoples R China -- [Chen, H. Y. -- Gao, X. Y. -- Li, Y. B. -- Qi, H. R. -- Shen, C. P.] Beihang Univ, Beijing 100191, Peoples R China -- [Li, Lei] Beijing Inst Petrochem Technol, Beijing 102617, Peoples R China -- [Albrecht, M. -- Chen, S. -- Held, T. -- Huang, G. S. -- Kopf, B. -- Pelizaeus, M. -- Wiedner, U.] Ruhr Univ Bochum, D-44780 Bochum, Germany -- [Albayrak, O. -- Bennett, J. V. -- Briere, R. A. -- Ke, B. C.] Carnegie Mellon Univ, Pittsburgh, PA 15213 USA -- [Liu, Feng -- Mo, Y. J. -- Zhang, Z. H.] Cent China Normal Univ, Wuhan 430079, Peoples R China -- [Ye, M. H.] China Ctr Adv Sci & Technol, Beijing 100190, Peoples R China -- [Nisar, S.] COMSATS Inst Informat Technol, Def Rd,Raiwind Rd, Lahore 54000, Pakistan -- [Achasov, N. -- Muchnoi, N. Yu. -- Nikolaev, I. B.] GI Budker Inst Nucl Phys SB RAS BINP, Novosibirsk 630090, Russia -- [Goetzen, K. -- Peters, K.] GSI Helmholtzctr Heavy Ion Res GmbH, D-64291 Darmstadt, Germany -- [Liao, G. R. -- Wei, D. H. -- Yang, Y. X.] Guangxi Normal Univ, Guilin 541004, Peoples R China -- [Gu, Y. T. -- Liu, H. B. -- Ruan, X. D.] Guangxi Univ, Nanning 530004, Peoples R China -- [Li, K. -- Xu, Q. N.] Hangzhou Normal Univ, Hangzhou 310036, Zhejiang, Peoples R China -- [Dbeyssi, A. -- Fritsch, M. -- Kliemt, R. -- Larin, P. -- Lin, D. X. -- Maas, F. E. -- Morales, C. Morales -- Nerling, F. -- Rosner, Ch. -- Wang, Y. D.] Helmholtz Inst Mainz, Johann Joachim Becher Weg 45, D-55099 Mainz, Germany -- [Hao, X. Q. -- Huang, J. S. -- Sun, J. F.] Henan Normal Univ, Xinxiang 453007, Peoples R China -- [Lara, M. -- Liu, H. H.] Henan Univ Sci & Technol, Luoyang 471003, Peoples R China -- [Cheng, H. P. -- Jiao, Z. -- Lu, H. J.] Huangshan Coll, Huangshan 245000, Peoples R China -- [Xiao, D. -- Zeng, Y.] Hunan Univ, Changsha 410082, Hunan, Peoples R China -- [Bennett, D. W. -- Mitchell, R. E. -- Sun, Z. T.] Indiana Univ, Bloomington, IN 47405 USA -- [Ferroli, R. Baldini -- Bertani, M. -- Caleaterra, A. -- Felici, G. -- Patteri, P. -- Zallo, A.] Ist Nazl Fis Nucl, Lab Nazl Frascati, I-00044 Frascati, Italy -- [Pacetti, S.] Ist Nazl Fis Nucl, I-06100 Perugia, Italy -- [Pacetti, S.] Univ Perugia, I-06100 Perugia, Italy -- [Bettonin, D. -- Cibinetto, G. -- Farinelli, R. -- Fioravanti, E.] Ist Nazl Fis Nucl, Sez Ferrara, I-44122 Ferrara, Italy -- [Farinelli, R. -- Savrie, M.] Univ Ferrara, I-44122 Ferrara, Italy -- [Denig, A. -- Feldbauer, F. -- Fritsch, M. -- Gradl, W. -- Guo, Y. P. -- Hafner, A. -- Kiese, P. -- Kloss, B. -- Liu, Zhiqing -- Redmer, C. F. -- Ripka, M. -- Schumann, S. -- Wang, Y. Q. -- Weber, T. -- Weidenkaff, P.] Johannes Gutenberg Univ Mainz, Johann Joachim Becher Weg 45, D-55099 Mainz, Germany -- [Boger, E. -- Boyko, I. -- Chelkov, G. -- Dedovich, D. -- Denysenko, I. -- Fedorov, O. -- Nefedov, Y. -- Sarantsev, A. -- Zhemchugov, A.] Joint Inst Nucl Res, Dubna 141980, Moscow Region, Russia -- [Kuehn, W. -- Lange, J. S. -- Liang, Y. T. -- Ullrich, M.] Univ Giessen, Inst Phys 2, Heinrich Buff Ring 16, D-35392 Giessen, Germany -- [Haddadi, Z. -- Kalantar-Nayestanaki, N. -- Kavatsyuk, M. -- Loehner, H. -- Messchendorp, J. G. -- Tiemens, M.] Univ Groningen, KVI CART, NL-9747 AA Groningen, Netherlands -- [Chen, X. R. -- Liu, X. -- Yu, J. S.] Lanzhou Univ, Lanzhou 730000, Peoples R China -- [Ding, Y. -- Huang, Z. L. -- Liu, K. Y. -- Ma, F. C.] Liaoning Univ, Shenyang 110036, Peoples R China -- [Guo, L. B. -- Hu, C. -- Luo, C. L. -- Ping, J. L. -- Xie, Y. G. -- Zhong, B.] Nanjing Normal Univ, Nanjing 210023, Jiangsu, Peoples R China -- [Chen, S. J. -- Dou, Z. L. -- Huang, X. Z. -- Huang, Y. -- Qi, M. -- Yuan, W. L. -- Zhang, C.] Nanjing Univ, Nanjing 210093, Jiangsu, Peoples R China -- [Dong, C. -- Gong, L. -- Ji, Q. P. -- Jiang, X. Y. -- Kang, X. S. -- Li, X. Q. -- Liu, Y. B. -- Ma, X. N. -- Shen, P. X. -- Wang, B. -- Yu, C. X. -- Zhang, S. Q. -- Zhao, M. G.] Nankai Univ, Tianjin 300071, Peoples R China -- [Ban, Y. -- Chu, X. K. -- Li, F. Y. -- Liu, L. D. -- Mao, Y. J. -- Shan, W. -- Wang, D. -- Wang, D. Y.] Peking Univ, Beijing 100871, Peoples R China -- [Li, Jin -- Olsen, S. L.] Seoul Natl Univ, Seoul 151747, South Korea -- [Huang, X. T. -- Jiao, J. B. -- Li, K. -- Li, Q. Y. -- Li, T. -- Li, X. L. -- Ma, L. L. -- Ma, Y. M. -- Qin, L. Q. -- Wang, M. -- Zhang, X. Y. -- Zheng, W. J.] Shandong Univ, Jinan 250100, Peoples R China -- [Dai, J. P. -- Liu, B. -- Yang, H. J.] Shanghai Jiao Tong Univ, Shanghai 200240, Peoples R China -- [Liu, F. H.] Shanxi Univ, Taiyuan 030006, Peoples R China -- [Liang, Y. F. -- Tang, C. 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M. -- Julin, A. -- Muramatsu, H. -- Poling, R.] Univ Minnesota, Minneapolis, MN 55455 USA -- [Ambrose, D. J. -- Thorndike, E. H.] Univ Rochester, Rochester, NY 14627 USA -- [Zhu, S. H.] Univ Sci & Technol Liaoning, Anshan 114051, Peoples R China -- [An, Q. -- Fang, X. -- Feng, C. Q. -- Gao, X. L. -- Gao, Z. -- Huang, G. S. -- Li, Cheng -- Liang, H. -- Liu, D. -- Liu, J. B. -- Liu, S. B. -- Pan, Y. -- Peng, H. P. -- Shao, M. -- Sun, Y. J. -- Wang, W. P. -- Wang, Z. H. -- Xia, L. -- Yan, W. C. -- Zeng, Z. -- Zhang, Y. T. -- Zhang, Z. P. -- Zhao, Lei -- Zhao, Z. G. -- Zhou, X. K. -- Zhou, X. R. -- Zhu, Y. C.] Univ Sci & Technol China, Hefei 230026, Peoples R China -- [Xiao, Z. J. -- Zheng, B.] Univ South China, Hengyang 421001, Peoples R China -- [Hussain, T. -- Rashid, K. H. -- Zafar, A. A.] Univ Punjab, Lahore, Pakistan -- [Amoroso, A. -- Bianchi, F. -- Destefanis, M. -- De Mori, F. -- Greco, M. -- Hu, J. F. -- Maggiora, M. -- Marcello, S. -- Sosio, S. -- Spataro, S. -- Yan, W. 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Subjects
Semileptonic decays, E(+)E(-), Physics, semileptonic decays, Monte-carlo, Physics, particles & fields, Absolute branching fraction, Physics, nuclear, Charmed mesons, CP Violation, Deterioration, CKM Matrix, charmed mesons, BESIII/BEPCII, absolute branching fraction
Abstract

WOS: 000389144400002, By analyzing 2.93 fb(-1) data collected at the center-of-mass energy root s = 3.773 GeV with the BESIII detector, we measure the absolute branching fraction of the semileptonic decay D+ -> (K) over bar (0)e(+)nu(e) to be B(D (+) -> (K) over bar (0)e(+)nu(e)) = (8.59 +/- 0.14 +/- 0.21)% using (K) over bar (0) -> K-S(0) -> pi(0) pi(0), where the first uncertainty is statistical and the second systematic. Our result is consistent with previous measurements within uncertainties.., National Key Basic Research Program of China [2009CB825204, 2015CB856700]; National Natural Science Foundation of China (NSFC) [10935007, 11125525, 11235011, 11305180, 11322544, 11335008, 11425524, 11475123, 11405046, U1332103]; Chinese Academy of Sciences (CAS) Large-Scale Scientific Facility Program; CAS Center for Excellence in Particle Physics (CCEPP); Collaborative Innovation Center for Particles and Interactions (CICPI); Joint Large-Scale Scientific Facility Funds of NSFC [11179007, U1232201, U1332201, U1532101]; Joint Large-Scale Scientific Facility Funds of CAS [KJCX2-YW-N29, KJCX2-YW-N45]; 100 Talents Program of CAS; National 1000 Talents Program of China; IN-PAC and Shanghai Key Laboratory for Particle Physics and Cosmology; German Research Foundation DFG (Collaborative Research Center) [CRC-1044]; Istituto Nazionale di Fisica Nucleare, Italy; Koninklijke Nederlandse Akademie van Wetenschappen (KNAW) [530-4CDP03]; Ministry of Development of Turkey [DPT2006K-120470]; National Natural Science Foundation of China (NSFC); Russian Foundation for Basic Research [14-07-91152]; Swedish Resarch Council; U. S. Department of Energy [DE-FG02-04ER41291, DE-FG02-05ER41374, DE-SC0012069, DESC0010118]; U.S. National Science Foundation; University of Groningen (RuG); Helmholtzzentrum fuer Schwerionenforschung GmbH (GSI), Darmstadt; WCU Program of National Research Foundation of Korea [R32-2008-000-10155-0], Supported by National Key Basic Research Program of China (2009CB825204, 2015CB856700), National Natural Science Foundation of China (NSFC) (10935007, 11125525, 11235011, 11305180, 11322544, 11335008, 11425524, 11475123), Chinese Academy of Sciences (CAS) Large-Scale Scientific Facility Program, CAS Center for Excellence in Particle Physics (CCEPP), Collaborative Innovation Center for Particles and Interactions (CICPI), Joint Large-Scale Scientific Facility Funds of NSFC and CAS (11179007, U1232201, U1332201, U1532101), CAS (KJCX2-YW-N29, KJCX2-YW-N45), 100 Talents Program of CAS, National 1000 Talents Program of China, IN-PAC and Shanghai Key Laboratory for Particle Physics and Cosmology, German Research Foundation DFG (Collaborative Research Center CRC-1044), Istituto Nazionale di Fisica Nucleare, Italy, Koninklijke Nederlandse Akademie van Wetenschappen (KNAW) (530-4CDP03), Ministry of Development of Turkey (DPT2006K-120470), National Natural Science Foundation of China (NSFC) (11405046, U1332103), Russian Foundation for Basic Research (14-07-91152), Swedish Resarch Council, U. S. Department of Energy (DE-FG02-04ER41291, DE-FG02-05ER41374, DE-SC0012069, DESC0010118), U.S. National Science Foundation, University of Groningen (RuG) and Helmholtzzentrum fuer Schwerionenforschung GmbH (GSI), Darmstadt, WCU Program of National Research Foundation of Korea (R32-2008-000-10155-0).

Published
2016

48. Measurement of the branching fraction for psi(3770) -> gamma chi c0

Author

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Abstract

WOS: 000368783600015, By analyzing a data set of 2.92 fb(-1) of e(+) e(-) collision data taken at root s = 3.773 GeVand 106.41 x 10(6) psi(3686) decays taken at root s = 3.686 GeVwith the BESIII detector at the BEPCII collider, we measure the branching fraction and the partial decay width for psi(3770)->gamma chi c0 to be B(psi(3770)->gamma chi c0) = (6.88 +/- 0.28 +/- 0.67) x 10(-3) and Gamma[psi(3770)->gamma chi c0] = (187 +/- 8 +/- 19) keV, respectively. These are the most precise measurements to date. (C) 2015 The Authors. Published by Elsevier B.V., National Key Basic Research Program of China [2009CB825204, 2015CB856700]; National Natural Science Foundation of China (NSFC) [10935007, 11125525, 11235011, 11305180, 11322544, 11335008, 11425524]; Chinese Academy of Sciences (CAS) Large-Scale Scientific Facility Program; NSFC [11179007, U1232201, U1332201]; CAS [11179007, U1232201, U1332201, KJCX2-YW-N29, KJCX2-YW-N45]; 100 Talents Program of CAS; CAS Center for Excellence in Particle Physics (CCEPP); INPAC; Shanghai Key Laboratory for Particle Physics and Cosmology; German Research Foundation DFG under Collaborative Research Center [CRC-1044]; Istituto Nazionale di Fisica Nucleare, Italy; Ministry of Development of Turkey [DPT2006K-120470]; Russian Foundation for Basic Research [14-07-91152]; U.S. Department of Energy [DE-FG02-04ER41291, DE-FG02-05ER41374, DE-FG02-94ER40823, DESC0010118]; U.S. National Science Foundation; University of Groningen (RuG); Helmholtzzentrum fur Schwerionenforschung GmbH (GSI), Darmstadt; WCU Program of National Research Foundation of Korea [R32-2008-000-10155-0], The BESIII collaboration thanks the staff of BEPCII and the IHEP computing center for their strong support. This work is supported in part by the National Key Basic Research Program of China under Contract Nos. 2009CB825204 and 2015CB856700; National Natural Science Foundation of China (NSFC) under Contracts Nos. 10935007, 11125525, 11235011, 11305180, 11322544, 11335008, 11425524; the Chinese Academy of Sciences (CAS) Large-Scale Scientific Facility Program; Joint Large-Scale Scientific Facility Funds of the NSFC and CAS under Contracts Nos. 11179007, U1232201, U1332201; CAS under Contracts Nos. KJCX2-YW-N29, KJCX2-YW-N45; 100 Talents Program of CAS; the CAS Center for Excellence in Particle Physics (CCEPP); INPAC and Shanghai Key Laboratory for Particle Physics and Cosmology; German Research Foundation DFG under Collaborative Research Center Contract No. CRC-1044; Istituto Nazionale di Fisica Nucleare, Italy; Ministry of Development of Turkey under Contract No. DPT2006K-120470; Russian Foundation for Basic Research under Contract No. 14-07-91152; U.S. Department of Energy under Contracts Nos. DE-FG02-04ER41291, DE-FG02-05ER41374, DE-FG02-94ER40823, DESC0010118; U.S. National Science Foundation; University of Groningen (RuG) and the Helmholtzzentrum fur Schwerionenforschung GmbH (GSI), Darmstadt; WCU Program of National Research Foundation of Korea under Contract No. R32-2008-000-10155-0.

Published
2016

49. Measurement of the e(+)e(-) -> pi(+) pi(-) cross section between 600 and 900 MeV using initial state radiation

Author

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C. -- Zhuang, J.] State Key Lab Particle Detect & Elect, Hefei 230026, Peoples R China -- [Cakir, O.] Ankara Univ, TR-06100 Ankara, Turkey -- [Yuncu, A.] Bogazici Univ, TR-34342 Istanbul, Turkey -- [Boger, E. -- Chelkov, G. -- Zhemchugov, A.] Moscow Inst Phys & Technol, Moscow 141700, Russia -- [Chelkov, G.] Tomsk State Univ, Funct Elect Lab, Tomsk 634050, Russia -- [Achasov, M. N. -- Muchnoi, N. Yu -- Nikolaev, I. B.] Novosibirsk State Univ, Novosibirsk 630090, Russia -- [Sarantsev, A.] PNPI, NRC Kurchatov Inst, Gatchina 188300, Russia -- [Lou, X. C.] Univ Texas Dallas, Richardson, TX 75083 USA -- [Kolcu, O. B.] Istanbul Arel Univ, TR-34295 Istanbul, Turkey, Uludağ Üniversitesi/Fen-Edebiyat Fakültesi/Fizik Bölümü., Tapan, İlhan, and Research unit Nuclear & Hadron Physics

Subjects
Nuclear and High Energy Physics, Particle physics, BESIII, детектор, Hadron, KLOE DETECTOR, BESIII, Hadronic cross section, Initial state radiation, Muon anomaly, Pion form factor, 7. Clean energy, 01 natural sciences, NO, law.invention, Subatomär fysik, Pion, law, CMD-2, 0103 physical sciences, Subatomic Physics, Physics, nuclear, Vacuum polarization, 010306 general physics, Collider, Physics, ELECTRON-POSITRON ANNIHILATION, HADRONIC CONTRIBUTIONS, Luminosity (scattering theory), FLAVOR FACTORIES, 010308 nuclear & particles physics, SIGMA(E(+)E(-), Form factor (quantum field theory), G-2, Order (ring theory), Mesons, Detector, Lattice QCD, lcsh:QC1-999, BEPCII, коллайдер, Astronomy & astrophysics, Physics, particles & fields, PI(+)PI(-)), Energy (signal processing), lcsh:Physics
Abstract

WOS: 000368783600087, We extract the e(+) e(-) -> pi(+) pi(-) cross section in the energy range between 600 and 900 MeV, exploiting the method of initial state radiation. A data set with an integrated luminosity of 2.93 fb(-1) taken at a center-of-mass energy of 3.773 GeV with the BESIII detector at the BEPCII collider is used. The cross section is measured with a systematic uncertainty of 0.9%. We extract the pion form factor vertical bar F pi vertical bar(2) as well as the contribution of the measured cross section to the leading-order hadronic vacuum polarization contribution to (g - 2)(mu). We find this value to be a(mu)(pi pi,LO) (600-900 MeV) = (368.2 +/- 2.5(stat)+/- 3.3(sys)).10(-10), which is between the corresponding values using the BaBar or KLOE data. (C) 2015 The Authors. Published by Elsevier B.V., National Key Basic Research Program of China [2015CB856700]; National Natural Science Foundation of China (NSFC) [11125525, 11235011, 11322544, 11335008, 11425524]; Chinese Academy of Sciences (CAS) Large-Scale Scientific Facility Program; CAS Center for Excellence in Particle Physics (CCEPP); Collaborative Innovation Center for Particles and Interactions (CICPI); Joint Large-Scale Scientific Facility Funds of the NSFC; CAS [11179007, U1232201, U1332201, KJCX2-YW-N29, KJCX2-YW-N45]; 100 Talents Program of CAS; National 1000 Talents Program of China; INPAC; Shanghai Key Laboratory for Particle Physics and Cosmology; German Research Foundation DFG [Collaborative Research Center CRC-1044]; Istituto Nazionale di Fisica Nucleare, Italy; Ministry of Development of Turkey [DPT2006K-120470]; Russian Foundation for Basic Research [14-07-91152]; Swedish Resarch Council; U.S. Department of Energy [DE-FG02-04ER41291, DE-FG02-05ER41374, DE-FG02-94ER40823, DESC0010118]; U.S. National Science Foundation; University of Groningen (RuG); Helmholtzzentrum fur Schwerionenforschung GmbH (GSI), Darmstadt; WCU Program of National Research Foundation of Korea [R32-2008-000-10155-0], The BESIII Collaboration thanks the staff of BEPCII and the IHEP computing center for their strong support. We thank Thomas Teubner for the recalculation of amupi pi,LO (600-900 MeV) and Fedor Ignatov for the useful discussions. This work is supported in part by National Key Basic Research Program of China under Contract No. 2015CB856700; National Natural Science Foundation of China (NSFC) under Contract Nos. 11125525, 11235011, 11322544, 11335008, 11425524; the Chinese Academy of Sciences (CAS) Large-Scale Scientific Facility Program; the CAS Center for Excellence in Particle Physics (CCEPP); the Collaborative Innovation Center for Particles and Interactions (CICPI); Joint Large-Scale Scientific Facility Funds of the NSFC and CAS under Contract Nos. 11179007, U1232201, U1332201; CAS under Contract Nos. KJCX2-YW-N29, KJCX2-YW-N45; 100 Talents Program of CAS; National 1000 Talents Program of China; INPAC and Shanghai Key Laboratory for Particle Physics and Cosmology; German Research Foundation DFG under Contract No. Collaborative Research Center CRC-1044; Istituto Nazionale di Fisica Nucleare, Italy; Ministry of Development of Turkey under Contract No. DPT2006K-120470; Russian Foundation for Basic Research under Contract No. 14-07-91152; The Swedish Resarch Council; U.S. Department of Energy under Contract Nos. DE-FG02-04ER41291, DE-FG02-05ER41374, DE-FG02-94ER40823, DESC0010118; U.S. National Science Foundation; University of Groningen (RuG) and the Helmholtzzentrum fur Schwerionenforschung GmbH (GSI), Darmstadt; WCU Program of National Research Foundation of Korea under Contract No. R32-2008-000-10155-0.

Published
2016

50. Inhibition of microRNA-21 increases radiosensitivity of esophageal cancer cells through phosphatase and tensin homolog deleted on chromosome 10 activation

Author

Xingya Chen, Xiaoan Zhang, Huang S, Wenjie Chen, Li Xq, and S.-M. Che

Subjects
Oncogene, Gastroenterology, General Medicine, Biology, Molecular biology, Squamous carcinoma, Reverse transcription polymerase chain reaction, Radioresistance, Cancer research, biology.protein, Tensin, PTEN, Radiosensitivity, Protein kinase B
Abstract

The radioresistance of esophageal squamous cell carcinoma is a great obstacle to treatment. Although it has been demonstrated that microRNA-21 (miR-21) can act as an 'oncogene' in esophageal squamous cell carcinoma, its role in radioresistance remains unexplored. The aims of this study were to investigate the role of miR-21 in esophageal squamous carcinoma cells' radioresistance and to identify the possible mechanism. The relatively radioresistant esophageal squamous cancer TE-1 cells (TE-R60) was established by fractionated irradiation. By lentiviral transduction with miRZip-21, the miR-21 expression in TE-1 cells was stably downregulated, which was renamed as 'anti-miR-21 TE-1 cells.' The phosphatase and tensin homolog deleted on chromosome 10 (PTEN) was knocked down in anti-miR-21 TE-1 cells through short interfering RNA. The expression level of miR-21 and PTEN messenger RNA were measured by quantitative real-time reverse transcription polymerase chain reaction or reverse transcription polymerase chain reaction. The expression level of PTEN, phospho-Akt, and Akt protein were detected by Western blot. Clongenic assay was used to analyze the cells' radiosensitivity. miR-21 was overexpressed, and PTEN was suppressed in established radioresistant TE-R60 cells compared with the parent cells (1.3-fold and 70.83%). The inhibition of miR-21 significantly increased the cells' radiosensitivity (P

Published
2012

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