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515 results on '"Li, Zhi Ping"'

1. Deep Learning-Based Analysis and Dynamic Forecasting of Multidimensional Factors Affecting Educational Quality: An Empirical Study

Author

Wang, Jiao, Li, Zhi Ping, Filipe, Joaquim, Editorial Board Member, Ghosh, Ashish, Editorial Board Member, Prates, Raquel Oliveira, Editorial Board Member, Zhou, Lizhu, Editorial Board Member, Gan, Jianhou, editor, Pan, Yi, editor, Zhou, Juxiang, editor, Liu, Dong, editor, Song, Xianhua, editor, and Lu, Zeguang, editor

Published
2024
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11. Study on antioxidant activities of proteins and enzymatic hydrolysates of eight edible fungi

Author

WANG Yao-ran, ZHAO Yan, CHEN Ming-jie, WEI Chen-ying, ZHA Lei, and LI Zhi-ping

Subjects
edible fungi, protein, hydrolysate, antioxidant activity, amino acids, Food processing and manufacture, TP368-456
Abstract

Objective: This study focused on the antioxidant activities of eight edible fungiproteins and their hydrolysates. Methods: Eight edible fungi proteins were hydrolyzed using alkaline protease. DPPH free radical scavenging activity, ABTS free radical scavenging activity, Fe2+ chelation rate and reducing power were used to evaluate antioxidant activity. Results: SDS-PAGE electrophoretic profile results indicated that alkaline protease was efficient in hydrolyzing proteins into low molecular weight peptides and amino acid; the antioxidant activity of the alkaline proteolysis product of Volvariellavolvacea was the highest with DPPH free radical scavenging ability （5 140.45±5.35） μg Trolox/g, ABTS free radical scavenging ability （6.97±0.27） mmol Trolox/L, and Fe2+ chelation rate （79.86±0.45）% and the reducing power （0.350±0.001）. Moreover, the amino acid composition was also determined, containing eight essential amino acids （230.43±5.35） mg/g and hydrophobic （209.95±4.95） mg/g, negatively charged （115.89±2.32） mg/g and aromatic amino acids （57.86±1.74） mg/g with high antioxidant activity. Conclusion: The alkaline proteolysis product of Volvariellavolvacea has good antioxidant activity and was rich in essential, hydrophobic, negatively charged and aromatic amino acids.

Published
2022
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21. Finding the Optimal Bus-Routes Based on Data Mining Method

Author

Wang, Yong, Liu, Yang, Zhang, Cheng-zhi, Li, Zhi-ping, Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Pandu Rangan, C., editor, Steffen, Bernhard, editor, Sudan, Madhu, editor, Terzopoulos, Demetri, editor, Tygar, Doug, editor, Vardi, Moshe Y., editor, Weikum, Gerhard, editor, Huang, De-Shuang, editor, Bevilacqua, Vitoantonio, editor, Figueroa, Juan Carlos, editor, and Premaratne, Prashan, editor

Published
2013
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39. Targeting Diagnosis of High‐Risk Papillary Thyroid Carcinoma Using Ultrasound Contrast Agent With the BRAFV600E Mutation: An Experimental Study.

Author

Xie, Fang, Yan, Lin, Li, Yi‐Ming, Lan, Yu, Xiao, Jing, Zhang, Ming‐Bo, Jin, Zhuang, Zhang, Ying, Tian, Xiao‐Qi, Zhu, Ya‐Qiong, Li, Zhi‐Ping, and Luo, Yu‐Kun

Subjects
MICROBUBBLE diagnosis, ULTRASOUND contrast media, CONTRAST-enhanced ultrasound, PAPILLARY carcinoma, THYROID cancer, ATOMIC force microscopy, DIAGNOSIS
Abstract

Objective: High‐risk papillary thyroid carcinoma (PTC) patients with BRAF mutation have lymph node and distant metastases and poor prognosis. Therefore, this study aims to develop a targeted ultrasound contrast agent for the BRAFV600E mutation to screen high‐risk PTC at early stage. Methods: The targeted lipid nanobubbles carrying BRAFV600E antibody were prepared using thin film hydration‐sonication and avidin‐biotin binding methods. The physicochemical properties and stability of the targeted nanobubbles were detected by transmission electron microscopy, atomic force microscopy, and confocal laser scanning microscopy. The target binding abilities of the targeted nanobubbles in the PTC cells (B‐CPAP) overexpressed mutant BRAFV600E were evaluated by immunofluorescence staining, quantitative real‐time polymerase chain reaction, western blot, and fluorescence microscopy. After PTC tumor models overexpressed mutant BRAFV600E were established, the enhanced images of targeted lipid nanobubbles and untargeted lipid nanobubbles on PTC tumors in nude mice were observed using contrast‐enhanced ultrasound imaging. Results: The targeted lipid nanobubbles revealed uniform, round morphology, and good stability with a nanoscale size. Besides, BRAFV600E monoclonal antibody was observed to be combined on the surface of lipid nanobubbles. Furthermore, the targeted nanobubbles had a good targeting diagnosis ability in PTC cells with BRAFV600E overexpression. Moreover, the targeted nanobubbles had better ultrasound enhancement and peak intensity of the time‐intensity curve (P <.001) in PTC tumors with BRAFV600E overexpression as compared to the untargeted lipid nanobubbles. Conclusion: The targeted lipid nanobubbles carrying BRAFV600E antibody could be regarded as a potential targeted ultrasound contrast agent for the diagnosis of high‐risk PTC. Access the CME test here and search by article title. [ABSTRACT FROM AUTHOR]

Published
2022
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48. Bevacizumab Combined with S‐1 and Raltitrexed for Patients with Metastatic Colorectal Cancer Refractory to Standard Therapies: A Phase II Study

Author

Chen, Ye, primary, Zhou, Yu‐Wen, additional, Cheng, Ke, additional, Li, Zhi‐Ping, additional, Luo, De‐Yun, additional, Qiu, Meng, additional, Li, Qiu, additional, Wang, Xin, additional, Shen, Ya‐Li, additional, Cao, Dan, additional, Yang, Yu, additional, Bi, Feng, additional, Liu, Ji‐Yan, additional, and Gou, Hong‐Feng, additional

Published
2021
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