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The wide-band wave-absorbing properties of novel metamaterial honeycomb sandwich structure composites were studied, and the effects of wave-absorbing honeycomb height and dielectric property on the wave-absorbing properties of novel metamaterial honeycomb sandwich structure composites were analyzed. The results show that the wave-absorbing properties of metamaterial structures are improved while the honeycomb heights is increased. The matching effect of metamaterial structures and wave-absorbing honeycomb is improved firstly, and then decreased with the increase of the dielectric properties of wave-absorbing honeycomb. While ε′ is between 1.59-1.84 and ε″ is between 1.31-1.75, the matching effect is optimal. By the introduction of metamaterial structures, the average wave-absorbing properties at 1-2 GHz of novel metamaterial honeycomb sandwich structure composites are significantly improved, and the weight is greatly reduced.

The regulatory effects of phosvitin phosphopeptide (PPP) and its calcium chelate (PPP-Ca) on osteoblast differentiation in the co-culture system of osteoblast (MC3T3-E1) and osteoclast precursor (RAW264.7) were investigated. Cytotoxicity, alkaline phosphatase (AKP) activity, tartrate-resistant acid phosphatase (TRAP) activity and TRAP staining were analyzed. The mRNA expressions of RANKL/OPG pathway-related proteins in osteoblasts were further studied by RT-PCR. The results showed that PPP and PPP-Ca increased theAKP activity in the MC3T3-E1 system by 9.5% and 12.7%, respectively. In the MC3T3-E1 system, PPP and PPP-ca increased the mRNA expression levels from 0.92 to 1.25 and 1.39, respectively, for OPG, and from 1.00 to 1.23 and 1.45, respectively for RANKL. The results of this study showed that PPP and PPP-ca could effectively promote the differentiation of osteoblasts. The experimental results provide a research basis for further exploration of the role of phosphopeptides in the multi-cell model system and the development of functional activity of phosphopeptides. [ABSTRACT FROM AUTHOR]

Background and Aims: Increasing utilization of extended criteria donor leads to an increasing rate of early allograft failure after liver transplantation. However, consensus of definition of early allograft failure is lacking., Methods: A retrospective, multicenter study was performed to validate the Liver Graft Assessment Following Transplantation (L-GrAFT) risk model in a Chinese cohort of 942 adult patients undergoing primary liver transplantation at three Chinese centers. L-GrAFT (L-GrAFT 7 and L-GrAFT 10 ) was compared with existing models: the Early Allograft Failure Simplified Estimation (EASE) score, the model of early allograft function (MEAF), and the Early Allograft Dysfunction (EAD) model. Univariate and multivariate logistic regression were used to find risk factors of L-GrAFT high-risk group., Results: L-GrAFT 7 had an area under the curve of 0.85 in predicting 90-day graft survival, significantly superior to MEAF [area under the curve (AUC=0.78, p =0.044)] and EAD (AUC=0.78, p =0.006), while there was no statistical significance between the predicting abilities of L-GrAFT 7 and EASE (AUC=0.84, p >0.05). Furthermore, L-GrAFT 7 maintains good predicting ability in the subgroup of high-donor risk index (DRI) cases (AUC=0.83 vs. MEAF, p =0.007 vs. EAD, p =0.014) and recipients of donors after cardiac death (AUC=0.92 vs. EAD, p <0.001). Through multivariate analysis, pretransplant bilirubin level, units of packed red blood cells, and the DRI score were selected as independent risk factors of a L-GrAFT 7 high-risk group., Conclusions: The accuracy of L-GrAFT 7 in predicting early allograft failure was validated in a Chinese multicenter cohort, indicating that it has the potential to become an accurate endpoint of clinical practice and transitional study of machine perfusion., Competing Interests: The authors have no conflict of interests related to this publication., (© 2024 Authors.)