1. Platelet Parameters, C-Reactive Protein, and Depression: An Association Study
- Author
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Wang,Jin-Min, Yang,Kan-Di, Wu,Song-Ying, Zou,Xiang-Gu, Liao,Yuan-Sheng, Yang,Bin, Xie,Bu-Ni, Huang,Yan, Li,Shi-Ju, Ma,Hui-Jun, Wang,Jin-Min, Yang,Kan-Di, Wu,Song-Ying, Zou,Xiang-Gu, Liao,Yuan-Sheng, Yang,Bin, Xie,Bu-Ni, Huang,Yan, Li,Shi-Ju, and Ma,Hui-Jun
- Abstract
Jin-Min Wang,1,* Kan-Di Yang,2,* Song-Ying Wu,3 Xiang-Gu Zou,3 Yuan-Sheng Liao,1 Bin Yang,4 Bu-Ni Xie,1 Yan Huang,4 Shi-Ju Li,1 Hui-Jun Ma5 1Department of Internal Neurology, The Second Peopleâs Hospital Affiliated to Fujian University of Traditional Chinese Medicine, Fuzhou, 350003, Fujian, Peopleâs Republic of China; 2Department of Internal Neurology, Anxi County Hospital, Quanzhou, Fujian, 362400, Peopleâs Republic of China; 3Institute of Clinical Research, Fujian Academy of Chinese Medical Sciences, Fuzhou, 350003, Fujian, Peopleâs Republic of China; 4Department of Internal Neurology, Fuzhou Traditional Chinese Medicine Hospital, Fuzhou, 350001, Fujian, Peopleâs Republic of China; 5Department of General, Qiaokou Han Jia Dun Street Community Health Service Center, Wuhan, 430000, Hubei, Peopleâs Republic of China*These authors contributed equally to this workCorrespondence: Jin-Min WangDepartment of Internal Neurology, The Second Peopleâs Hospital Affiliated to Fujian University of Traditional Chinese Medicine, No. 282 of Wusi Road, Gulou District, Fuzhou, 350003, Fujian, Peopleâs Republic of ChinaTel +86-13960769905Fax +86-591-87825344Email drwang_wjm1298@163.comObjective: This study aims to investigate the correlation of platelet parameters and C-reactive protein (CRP) with depression.Methods: The clinical data of 61 patients with depression and 30 healthy control subjects were collected to compare the platelet parameters, CRP levels, and Hamilton Depression Rating Scale (HAMD) scores of the two groups for correlation analysis.Results: The results revealed that the body mass index (BMI) of patients with depression was lower (P < 0.05) than that of the healthy control subjects, and that this difference was more significant in women than in men. Patients with severe depression showed an increased mean platelet volume (MPV) (P < 0.05). In the patients with depression, MPV was positively correlated (P < 0.05) with HAM
- Published
- 2022