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28 results on '"Li, Shaoxun"'

17. Hybrid Nanoparticles Modified by Hyaluronic Acid Loading an HSP90 Inhibitor as a Novel Delivery System for Subcutaneous and Orthotopic Colon Cancer Therapy

Author

Pan,Chenwei, Zhang,Tiaotiao, Li,Shaoxun, Xu,Zhihua, Pan,Binhui, Xu,Sheng, Jin,Shuanghong, Lu,Guangrong, Yang,Shouxing, Xue,Zhanxiong, Chen,Ping, Shen,Xian, Wang,Fangyan, Xu,Changlong, Pan,Chenwei, Zhang,Tiaotiao, Li,Shaoxun, Xu,Zhihua, Pan,Binhui, Xu,Sheng, Jin,Shuanghong, Lu,Guangrong, Yang,Shouxing, Xue,Zhanxiong, Chen,Ping, Shen,Xian, Wang,Fangyan, and Xu,Changlong

Abstract

Chenwei Pan,1,* Tiaotiao Zhang,2,3,* Shaoxun Li,1,3,* Zhihua Xu,2,3 Binhui Pan,2,3 Sheng Xu,2,3 Shuanghong Jin,1,3 Guangrong Lu,2 Shouxing Yang,2 Zhanxiong Xue,2 Ping Chen,4 Xian Shen,5 Fangyan Wang,6 Changlong Xu2,7 1Department of Infectious Disease, Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, People’s Republic of China; 2Department of Gastroenterology, Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, People’s Republic of China; 3Second School of Medicine, Wenzhou Medical University, Wenzhou, Zhejiang, 325000, People’s Republic of China; 4Department of Infectious Disease, Shulan Hospital, Hangzhou, Zhejiang, 310012, People’s Republic of China; 5Department of Gastrointestinal Surgery, Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, People’s Republic of China; 6Department of Pathophysiology, School of Basic Medicine Science, Wenzhou Medical University, Wenzhou, Zhejiang, 325000, People’s Republic of China; 7Center for Diagnostics and Therapeutics, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, 30302, USA*These authors contributed equally to this workCorrespondence: Fangyan Wang; Changlong Xu Email wzyxywfy@126.com; xchlong@163.comBackground: As a therapeutic target for cancer treatment, HSP90 has been explored extensively. However, the significant side effects of the HSP90 inhibitor 17AAG have limited its clinical use.Methods: In this study, we used hyaluronic acid (HA)–decorated DOTAP–PLGA hybrid nanoparticles (HA-DOTAP-PLGA NPs) as 17AAG-delivery carriers for targeted colon cancer therapy.Results: Different methods were used to characterize the successful fabrication of these hybrid PLGA NPs. Our results demonstrated that inter

Published
2021

18. Hybrid Nanoparticles Modified by Hyaluronic Acid Loading an HSP90 Inhibitor as a Novel Delivery System for Subcutaneous and Orthotopic Colon Cancer Therapy

Author

Pan, Chenwei, primary, Zhang, Tiaotiao, additional, Li, Shaoxun, additional, Xu, Zhihua, additional, Pan, Binhui, additional, Xu, Sheng, additional, Jin, Shuanghong, additional, Lu, Guangrong, additional, Yang, Shouxing, additional, Xue, Zhanxiong, additional, Chen, Ping, additional, Shen, Xian, additional, Wang, Fangyan, additional, and Xu, Changlong, additional

Published
2021
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28. A UHF RFID reader baseband for multi-protocol with universal transmitter

Author

Qi Peng, Chun Zhang, Yingying Wang, and Li Shaoxun

Subjects
Engineering, business.industry, Transmitter, Chip, Microcontroller, CMOS, Ultra high frequency, Control register, Hardware_INTEGRATEDCIRCUITS, Baseband, Electronic engineering, Netlist, ComputerSystemsOrganization_SPECIAL-PURPOSEANDAPPLICATION-BASEDSYSTEMS, business, Computer hardware
Abstract

In this paper, a UHF RFID reader baseband for multi-protocol with universal transmitter is present. A universal transmitter is proposed that can support all of the coding method of UHF RFID, except that a MCU of DW8051core and some supported module are included in the chip. It provides flexible choice for users to select coding method and data rate by set the related control registers. The UHF RFID Reader IC is fabricated in 0.18μm CMOS technology. The area of digital part on the right of IC is 4.4mm2. EDA tool Synopsys PrimeTime PX has been exploited for power consumption estimation with post-layout netlist, which shows that the digital baseband consumes an average power of 4.9μW (1.8V) over a succession of receiving a sequence of response. The power will rise up to 220μW (1.8V), when containing the memory part.

Published
2013

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