Search

Your search keyword '"Li, Muzheng"' showing total 14 results
Start Over Author "Li, Muzheng"
14 results on '"Li, Muzheng"'

2. Protein structuromics: A new method for protein structure–function crosstalk in glioma.

Author

Xiao, Nan, Yang, Wenming, Wang, Jin, Li, Jiarong, Zhao, Ruoxuan, Li, Muzheng, Li, Chi, Liu, Kang, Li, Yingxin, Yin, Chaoqun, Chen, Zhibo, Li, Xingqi, and Jiang, Yun

Abstract

Glioma is a type of tumor that starts in the glial cells of the brain or spine. Since the 1800s, when the disease was first named, its survival rates have always been unsatisfactory. Despite great advances in molecular biology and traditional treatment methods, many questions regarding cancer occurrence and the underlying mechanism remain to be answered. In this study, we assessed the protein structural features of 20 oncogenes and 20 anti‐oncogenes via protein structure and dynamic analysis methods and 3D structural and systematic analyses of the structure–function relationships of proteins. All of these results directly indicate that unfavorable group proteins show more complex structures than favorable group proteins. As the tumor cell microenvironment changes, the balance of oncogene‐related and anti‐oncogene‐related proteins is disrupted, and most of the structures of the two groups of proteins will be disrupted. However, more unfavorable group proteins will maintain and refold to achieve their correct shape faster and perform their functions more quickly than favorable group proteins, and the former thus support cancer development. We hope that these analyses will help promote mechanistic research and the development of new treatments for glioma. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

5. High Serum Carbohydrate Antigen (CA) 125 Level Is Associated With Poor Prognosis in Patients With Light-Chain Cardiac Amyloidosis

Author

Li, Muzheng, primary, Wu, Zhijian, additional, Tudahun, Ilyas, additional, Liu, Na, additional, Lin, Qiuzhen, additional, Liu, Jiang, additional, Wang, Yingmin, additional, Chen, Mingxian, additional, Chen, Yaqin, additional, Qi, Nenghua, additional, Zhu, Qingyi, additional, Li, JunLi, additional, Li, Wei, additional, Tang, Jianjun, additional, and Liu, Qiming, additional

Published
2021
Full Text
View/download PDF

9. Additional file 1 of A real-world study on diagnosis and prognosis of light-chain cardiac amyloidosis in Southern China

Author

Wu, Zhijian, Li, Muzheng, Ilyas, Tudahun, Li, Wei, Zeng, Mu, Li, Fang, Liu, Yanxia, Chen, Mingxian, Chen, Yaqin, Zhu, Qingyi, Qi, Nenghua, Liu, Qiming, and Tang, Jianjun

Abstract

Additional file 1. Kaplan-Meier survival curves demonstrating differences in overall survival (months). The median survival time of AL-CA patients were diagnosed in the second half time (2016–2020) was longer than that of patients were diagnosed in the first half time (2012–2016) (12.00 vs 6.00, log-rank test, p = 0.35).

Published
2021
Full Text
View/download PDF

10. Clinical Implications of CA 125 Elevation in Patients with Cardiac Amyloidosis: An Observational Study

Author

Li, Muzheng, primary, Wu, Zhijian, additional, Tudahun, Ilyas, additional, Lin, Qiuzhen, additional, Liu, Na, additional, Liu, Jiang, additional, Wang, Yingmin, additional, Chen, Mingxian, additional, Chen, Yaqin, additional, Qi, Nenghua, additional, Zhu, Qingyi, additional, Li, Wei, additional, Tang, Jianjun, additional, and Liu, Qiming, additional

Published
2021
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results