1. The influence of the cancer label on perceptions and management decisions for low-grade prostate cancer.
- Author
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Berlin, Alejandro, Ramotar, Matthew, Santiago, Anna, Liu, Zhihui, Li, Joyce, Wolinsky, Howard, Wallis, Christopher, Chua, Melvin, Paner, Gladell, van der Kwast, Theodorus, Cooperberg, Matthew, Vickers, Andrew, Urbach, David, and Eggener, Scott
- Subjects
Male ,Humans ,Prostatic Neoplasms ,Prostate ,Prostate-Specific Antigen ,Adenocarcinoma ,Neoplasm Grading ,Logistic Models - Abstract
BACKGROUND: Grade Group 1 (GG1) prostate cancer should be managed with active surveillance (AS). Global uptake of AS remains disappointingly slow and heterogeneous. Removal of cancer labels has been proposed to reduce GG1 overtreatment. We sought to determine the impact of GG1 disease terminology on individuals perceptions and decision making. METHODS: Discrete choice experiments were conducted on 3 cohorts: healthy men, canonical partners (partners), and patients with GG1 (patients). Participants reported preferences in a series of vignettes with 2 scenarios each, permuting key opinion leader-endorsed descriptors: biopsy (adenocarcinoma, acinar neoplasm, prostatic acinar neoplasm of low malignant potential [PAN-LMP], prostatic acinar neoplasm of uncertain malignant potential), disease (cancer, neoplasm, tumor, growth), management decision (treatment, AS), and recurrence risk (6%, 3%, 1%,
- Published
- 2023