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482 results on '"Li, Fengwei"'

1. Generator polynomials of cyclic expurgated or extended Goppa codes

Author

Jia, Xue, Li, Fengwei, Sun, Huan, and Yue, Qin

Subjects
Computer Science - Information Theory
Abstract

Classical Goppa codes are a well-known class of codes with applications in code-based cryptography, which are a special case of alternant codes. Many papers are devoted to the search for Goppa codes with a cyclic extension or with a cyclic parity-check subcode. Let $\Bbb F_q$ be a finite field with $q=2^l$ elements, where $l$ is a positive integer. In this paper, we determine all the generator polynomials of cyclic expurgated or extended Goppa codes under some prescribed permutations induced by the projective general linear automorphism $A \in PGL_2(\Bbb F_q)$. Moreover, we provide some examples to support our findings.

Published
2024

16. A class of functions with low-valued Walsh spectrum

Author

Li, Fengwei, Wu, Yansheng, and Yue, Qin

Subjects
Computer Science - Information Theory
Abstract

Let $l\equiv 3\pmod 4$, $l\ne 3$, be a prime, $N=l^2$, $f=\frac{l(l-1)}2$ the multiplicative order of a prime $p$ modulo $N$, and $q=p^f$. In this paper, we investigate the Walsh spectrum of the monomial functions $f(x)={\rm Tr}_{q/p}(x^{\frac{q-1}{l^2}})$ in index two case. In special, we explicitly present the value distribution of the Walsh transform of $f(x)$ if $1+l=4p^h$, where $h$ is a class number of $\Bbb Q(\sqrt{-l})$., Comment: 15 pages. To appear in Discrete Applied Mathematics

Published
2019

24. Effects of cholesterol‐lowering probiotic fermentation on the active components and in vitro hypolipidemic activity of sea buckthorn juice.

Author

Fan, Ying, Shang, Yueling, Li, Fengwei, Liu, Jinbin, Wang, Dujun, Zhang, Ya, Yu, Xiaohong, and Wang, Wei

Subjects
SEA buckthorn, SHIKIMIC acid, LACTOBACILLUS plantarum, BILE salts, PHENOLS
Abstract

Sea buckthorn has lipid‐lowering properties and is widely used in the development of functional foods. In this study, a probiotic (Lactobacillus plantarum, Lp10211) with cholesterol‐lowering potential and acid and bile salt resistant was screened for the fermentation of sea buckthorn juice. Changes in the active ingredients, such as sugars and phenolics, before and after fermentation, as well as their in vitro lipid‐lowering activities, were compared. The contents of reducing and total sugars decreased substantially after fermentation. Lp10211 primarily utilized fructose for growth and reproduction, with a utilization rate of 76.9%. The phenolic compound content of sea buckthorn juice increased by 37.06% after fermentation and protected the phenolic components from degradation (protocatechuic and p‐coumaric acids) and produced new polyphenol (shikimic acid). Enhanced inhibition of pancreatic lipase activity (95.42%) and cholesterol micellar solubility (59.15%) was evident. The antioxidant properties of the fermentation broth were improved. Notably, Lp10211 preserved the color and reversed browning in sea buckthorn juice. The collective findings indicate that fermentation of sea buckthorn juice by Lp10211 may enhance the functional components and lipid‐lowering activity of sea buckthorn, which may provide a new approach for the development of lipid‐lowering foods. [ABSTRACT FROM AUTHOR]

Published
2024
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25. Optimal Algorithm of Isolated Toughness for Interval Graphs

Author

Li, Fengwei, Ye, Qingfang, Broersma, Hajo, Zhang, Xiaoyan, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Woeginger, Gerhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Zhang, Yong, editor, Xu, Yicheng, editor, and Tian, Hui, editor

Published
2021
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38. Structural overview and perspectives of the nuclear receptors, a major family as the direct targets forsmall-molecule drugs

Author

Li Fengwei, Song Chun, Zhang Youming, and Wu Dalei

Subjects
nuclear receptor, structure, drug target, small-molecule drug, Biochemistry, QD415-436, Genetics, QH426-470
Abstract

The nuclear receptors (NRs) are an evolutionarily related family of transcription factors, which share certain common structural characteristics and regulate the expressions of various genes by recognizing different response elements. NRs play important roles in cell differentiation, proliferation, survival and apoptosis, rendering them indispensable in many physiological activities including growth and metabolism. As a result, dysfunctions of NRs are closely related to a variety of diseases, such as diabetes, obesity, infertility, inflammation, the Alzheimer′s disease, cardiovascular diseases, prostate and breast cancers. Meanwhile, small-molecule drugs directly targeting NRs have been widely used in the treatment of above diseases. Here we summarize recent progress in the structural biology studies of NR family proteins. Compared with the dozens of structures of isolated DNA-binding domains (DBDs) and the striking more than a thousand of structures of isolated ligand-binding domains (LBDs) accumulated in the Protein Data Bank (PDB) over thirty years, by now there are only a small number of multi-domain NR complex structures, which reveal the integration of different NR domains capable of the allosteric signal transduction, or the detailed interactions between NR and various coregulator proteins. On the other hand, the structural information about several orphan NRs is still totally unavailable, hindering the further understanding of their functions. The fast development of new technologies in structural biology will certainly help us gain more comprehensive information of NR structures, inspiring the discovery of novel NR-targeting drugs with a new binding site beyond the classic LBD pockets and/or a new mechanism of action.

Published
2021
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50. Compartmentalized biosynthesis of mycophenolic acid

Author

Zhang, Wei, Du, Lei, Qu, Zepeng, Zhang, Xingwang, Li, Fengwei, Li, Zhong, Qi, Feifei, Wang, Xiao, Jiang, Yuanyuan, Men, Ping, Sun, Jingran, Cao, Shaona, Geng, Ce, Qi, Fengxia, Wan, Xiaobo, Liu, Changning, and Li, Shengying

Published
2019

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