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AIM:To observe the clinical effect of ciliary sulcus suture fixation of intraocular lens(IOL)with the scleral tunnel technique.METHODS: The clinical data of 36 patients(38 eyes)who underwent ciliary sulcus suture fixation of IOL with the scleral tunnel technique in our hospital from May 2021 to September 2023 were retrospectively analyzed. The patients were followed up for a total of 3-26 mo. The postoperative IOL position, visual acuity, refraction, intraocular pressure and complications were observed, and the results of tear film break-up time(BUT), corneal fluorescein staining(FL)and Schirmer Ⅰ test(SⅠt )were evaluated.RESULTS: The uncorrected visual acuity and best corrected visual acuity of all eyes were improved at 3 mo after surgery(all P

Background: This study aims to comprehensively evaluate the predictive accuracy of six widely used toric intraocular lens (IOL) calculators in eyes undergoing cataract surgery with toric IOL implantation. Methods: This retrospective study reviewed 53 eyes of 53 patients that underwent cataract extraction with toric IOL implantation using Zeiss 709 M. Six toric IOL calculators were evaluated: Barrett toric calculator (with predicted PCA, measured PCA, and TK), Kane formula (predicted PCA), and EVO 2.0 formula (predicted and measured PCA). Postoperative refractive astigmatism prediction errors were comprehensively calculated and analyzed using vector analysis. Results: The mean absolute prediction error (APE) ranged from 0.56 ± 0.37 D (Barrett TK) to 0.63 ± 0.46 D (Barrett predicted PCA, PPCA). The proportions of eyes achieving APE ≤ 1.0 D were highest for Barrett TK and Kane predicted PCA (90.6%). The highest proportions of eyes achieving APE ≤ 0.25 D and ≤ 0.50 D were observed with Barrett measured PCA (18.9% and 56.6%, respectively), while the lowest with Barrett PPCA (9.4% and 50.9%, respectively). The study found no statistically significant differences in mean absolute prediction error (APE) among the six calculators (χ² = 6.88, P = 0.23) and the centroid of PE (P = 0.93). A difference in mean APE was observed between the Barrett predicted PCA and Barrett TK calculators (P = 0.02). Conclusion: The study confirms the importance of considering posterior corneal astigmatism remains essential to achieving precise refractive outcomes but also underscores the need for ongoing refinement and evaluation to optimize surgical outcomes. [ABSTRACT FROM AUTHOR]

Delirium is a common complication of acute pancreatitis. Receptor-interacting protein kinase 3 (RIP3) is an activator of programmed cell necrosis. This study aimed to determine its ability to predict delirium after acute pancreatitis. Methods: In total, 297 patients with acute pancreatitis were prospectively enrolled in this study. Patients were divided into two subgroups (study and validation groups: 197 and 100 cases, respectively). Serum RIP3 levels were measured in all patients and in 100 healthy controls. Acute Physiology and Chronic Health Evaluation (APACHE) II, Ranson, and sequential organ failure assessment (SOFA) scores were used for the severity assessment. In-hospital delirium was observed as an outcome variable. Multifactorial analyses were performed to discern severity correlations and outcome associations. Results: Serum RIP3 levels were significantly higher in the patients than in the controls. Serum RIP3 levels had linear relationships under the restricted cubic spline and were independently correlated with APACHE II, Ranson, and SOFA scores. Serum RIP3 levels were linearly correlated with the likelihood of developing in-hospital delirium and exhibited a strong discrimination efficiency under the receiver operating characteristic curve. Serum RIP3 levels, coupled with APACHE II scores, Ranson scores, and SOFA scores, were the four independent predictors of in-hospital delirium. No interactions were revealed regarding its relevance to sex, age, or body mass index in subgroup analysis. These were integrated to form a model graphically represented by a nomogram that showed effective stability, clinical fit, and predictive ability for in-hospital delirium. The model was verified in the validation group. Conclusion: An incremental trend in serum RIP3 levels was notable after acute pancreatitis. Serum RIP3 levels are independently related to illness severity and occurrence of in-hospital delirium, indicating that serum RIP3 may be a potential biomarker of acute pancreatitis. [ABSTRACT FROM AUTHOR]

Some scalar double‐well problems eventually lead to a degenerate convex minimization problem with unique stress. We consider the adaptive conforming and nonconforming finite element methods for the scalar double‐well problem with the reliable a posteriori error analysis. A number of experiments confirm the effective decay rates of the methods. [ABSTRACT FROM AUTHOR]