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This article examines the practices of investigative journalism in China in changing times. It does so by focusing on the case study of Southern Metropolitan Daily (SMD), a well-known newspaper in China which built its name on investigative journalism. The aim is to understand how the changing social conditions have shaped investigative journalism and transformed the role performance of investigative journalists. Drawing on data from multiple sources, including archival research, in-depth interviews, and news content analysis, the study found that under a trio of pressures: technological disruption, economic downturn and most importantly tightened political control, the media have been repositioning and reorienting themselves in relation to power. Investigative journalism, although it still retains the name, has shifted to trumpeting the value of constructiveness rather than criticism. This study contributes to the ongoing debates on journalistic role performance by showing how the watchdog and facilitator roles are combined in the practice of Chinese investigative journalists in changing times. It reaffirms the complex cooccurrence of journalistic roles and adds insights into the possibility of roles overlapping, not only across different dimensions but within the same dimension of power relations. [ABSTRACT FROM AUTHOR]

Available polarization-difference imaging techniques face serious challenges in imaging speed and application range. To address these issues, this paper proposes an underwater dynamic polarization-difference imaging method with greater applicability. First, the intensity distribution of backscattered light is estimated via the Stokes vector. Afterward, the differential operation between the total intensity of light and the amplified estimation result of backscattered light makes clear imaging immediately accessible. Regardless of the movement states and polarization characteristics of the target, experimental results consistently demonstrate that the backscattered light can be eliminated to a great extent, and imaging quality and applicability are significantly enhanced. Meanwhile, the proposed method is immune to unexpected factors such as uneven illumination and has good stability. More importantly, there are also apparent advantages in terms of imaging time. [ABSTRACT FROM AUTHOR]

Photobiomodulation therapy, as an emerging treatment modality, has been widely used in dentistry. However, reports on blue light therapy for oral cancer are scarce. This study investigated the effects of 457 and 475 nm LED irradiation on SCC‐25 cells and explored the potential mechanisms underlying the impact of blue light. Both wavelengths were found to inhibit cell viability, induce oxidative stress, and cause cell cycle arrest without leading to cell death. Notably, the inhibitory effect of 457 nm blue light on cell proliferation was more sustained. Transcriptome sequencing was performed to explore the underlying mechanisms, revealing that blue light induced endoplasmic reticulum stress in SCC‐25 cells, with 457 nm light showing a more pronounced effect. Moreover, 457 nm blue light upregulated the expression of the aryl hydrocarbon receptor pathway, indicating potential therapeutic prospects for the combined use of blue light and pharmacological agents. [ABSTRACT FROM AUTHOR]

Light exposure has been proven to have a significant impact on human health. As a result, researchers are increasingly exploring its potential benefits and drawbacks. With advancements in understanding light and the manufacturing of light sources, modern health lighting has become widely utilized in daily life and plays a critical role in the prevention and treatment of various illnesses. The use of light in healthcare is a global trend, with many countries actively promoting the development and application of relevant scientific research and medical technology. This field has gained worldwide attention and support from scientists and doctors alike. In this review, we examine the application of lighting in human health and recent breakthroughs in light exposure related to pathology, therapeutic strategies, molecular changes, and more. Finally, we also discuss potential future developments and areas of application. [ABSTRACT FROM AUTHOR]

Probing elemental and molecular structural information with a high spatial resolution is a key bottleneck in determining unknown minerals in the fields of geology and space exploration. An untraditional confocal-controlled Raman-LIBS hybrid method with high spatial resolution and anti-drift properties has been developed to overcome this challenge. The method is the first to combine Rayleigh/reflected light, LIBS signal, and Raman spectrum to simultaneously measure geometrical topography and elemental and molecular structural information. The hybrid system utilizes real-time focus tracking the performance of Rayleigh/reflected light to achieve accurate spectral measurements. The axial-focusing resolution and lateral resolution for morphological imaging are improved to ∼15 nm and 600 nm, which improves the anti-drift capability and minimizes the laser ablation size, thereby achieving a high transverse resolution of ∼9 μm, and a high axial resolution of ∼10 μm. As a proof of concept, high-resolution topological and hybrid spectral maps of the Northwest Africa 13323 meteorite have been measured. The fusion of the LIBS and Raman data provides a detailed three-dimensional map of the elementary and compositional distributions of the meteorite. Further analysis of the D and G bands in the Raman map reveals structural information reflecting the thermal metamorphism of the meteorite. The proposed Raman-LIBS hybrid microscope provides valuable information for composition and structure analysis, and it is a powerful tool for studying unknown minerals in the fields of geology and space exploration. [ABSTRACT FROM AUTHOR]

Nanoscale laser arrays are attractive for their potential applications in highly integrated nanodevices, which are always obtained by nanowire arrays with complicated fabrication techniques. Here, a quite different nanolaser array is successfully realized based on a highly ordered core–shell CdS branched nanostructure with implanted Sn nanoparticles in junctions that split the individual multichannel nanostructures to various microcavities with effective light confinement and oscillation, thus to achieve a multipoint nanolaser array. Under the excitation of an ultraviolet laser, the strong band‐edge emission can be well reflected between Sn nanoparticles at junctions and effectively scattered into branch segments due to Sn nanoparticles existence in junctions, furthermore oscillating in various microcavities along trunks or branches to form multipoint lasing from Fabry‐Pérot (F‐P) mode with a quality factor up to 990 and the low threshold at around 3.78 MW cm−2. The corresponding fluorescent microscope images further demonstrate the formation of multipoint F‐P lasing at various segments. The theoretical simulation indicates that implanted Sn nanoparticles work as hot point to enhance the confinement of light around the Sn centers. The existence of surface plasmon from the Sn metal particles is further confirmed by the polarization dependent photoluminescence measurement. The results provide a new way to realize nanolaser arrays. [ABSTRACT FROM AUTHOR]

Laser induced breakdown spectroscopy (LIBS) is a promising analytical technique based on the interaction between laser and material, which can quantitatively analyse the composition and content of material from the perspective of spectroscopy. The element distribution of non-uniform samples, such as natural ore, can be obtained by pointwise scanning without pretreatment. LIBS excitation intensity is the highest near the focus, so low imaging speed and low focusing accuracy will lead to unreliable element maps. Hence, an ultrasensitive technique called unilateral-shift-subtracting confocal controlled LIBS microscopy (UCCLIBS) was prepared to rapidly acquire high spatial resolution multi-elemental maps of the sample surface, which utilizes a laser induced breakdown spectrometer attached to a unilateral-shift-subtracting confocal microscope. A surface axial focusing ability of approximately 18 nm under 20× objective lens with the N.A. value of 0.4 is obtained, which is more than two orders of magnitude higher than that of ever traditional LIBS approaches, and the inherent anti-drift capability is successfully realized. The chemometric method of principal component analysis (PCA) is applied to the multi-element analysis of agate ore, which improved the accuracy and efficiency of sample analysis. We show the multi-layer element map of a solid-state electrolyte with a tomographic resolution of 2.3 μm. With these excellent properties, the UCCLIBS might provide a new idea for the detection of three-dimensional elemental characterization of minerals and chemical materials. We present a novel technique termed unilateral-shift-subtracting confocal laser-induced breakdown microscopy (UCLIBS), which utilizes a laser induced breakdown spectrometer attached to a unilateral-shift-subtracting confocal microscope to rapidly acquire high spatial resolution multi-elemental maps of the sample surface. This technique shows a surface axial focusing ability of approximately 18 nm under 20× objective lens with the N.A. value of 0.4, which is more than two orders of magnitude higher than that the traditional LIBS approaches, and provides inherent anti-drift capability. The chemometric method of principal component analysis (PCA) is applied to the multi element analysis of agate ore, which improved the accuracy and efficiency of sample analysis. We show the multi-layer element map of a solid-state electrolyte with a tomographic resolution of 2.3 μm. The experimental results demonstrate that the UCLIBS can be extended to the three-dimensional elemental characterization of minerals and chemical materials. [Display omitted] • The system has a high spatial resolution and can be realized Multi-layer elemental maps for the solid-state electrolyte with a depth resolution of 2.3 μm. • This technique shows a high axial focusing ability of approximately 18 nm, which is more than two orders of magnitude higher than that the traditional LIBS approaches. • UCLIBS system has a transverse resolution of 600 nm, and its imaging stability is better than the traditional LIBS system. [ABSTRACT FROM AUTHOR]

Androgenetic alopecia (AGA) is a prevalent hair loss disorder and influenced by genetic, hormonal, and environmental factors. Minoxidil and finasteride have been widely used for treating AGA. However, the side effects associated with these drugs often lead to poor patient compliance. In contrast, photobiomodulation (PBM), due to its safety and non-invasiveness, holds promising prospects for use. Although the promoting effects of PBM on AGA have been reported, the mechanisms by which PBM affects dermal papilla cells (DPCs) remain largely unknown. Hence, this study explored the impacts of both continuous wave (CW) and pulsed wave (PW) PBM on DPCs, and revealed the underlying actions of light parameters in PBM. Orthogonal experiments were conducted to evaluate the effects of CW PBM on DPCs at varying irradiances and doses, indicating that irradiance was the crucial parameter, as well as cell viability and proliferation were maximized at 8 mW/cm 2 and 8 J/cm 2 . For PW PBM, response surface methodology was employed to determine the influences of duty cycles, frequencies, and doses. The findings highlighted frequency as a primary factor, with the optimum cell viability observed at peak irradiance 10 mW/cm 2 , duty cycle 80 %, 500 Hz, and 8.8 J/cm 2 . Notably, PBM could enhance cell viability, proliferation, and migration in DPCs by activating the Wnt/β-Catenin signaling and suppressing Transforming Growth Factor signaling, particularly when applied in pulsed mode. Overall, this study determined the key light parameters that influence PBM effectiveness, further identified the optimal light conditions, and preliminary revealed into the mechanisms of PBM in DPCs, highlighting that PW PBM may be a competitive therapeutic option for alleviating AGA in the future., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024. Published by Elsevier B.V.)

Previous underwater imaging methods have not developed a clear idea of estimating the degree of polarization of target light (Pobj). To address this issue, this Letter answers the question of how the estimation result of Pobj affects clear imaging. First, the theoretical derivation states that Pobj is simply a scale modulation factor of the imaging result. Second, experiments are conducted for validation, and results conform well to the derivation. Hence, the effect of the estimated Pobj on clear imaging is obtained. This parameter only influences brightness rather than contrast but may cause noise amplification as well as the unfavorable result of negative pixels. Therefore, no precise estimation is needed; pick the value near the ends of the definition domain directly and take the absolute value. Based on these, a new imaging formula is proposed, enabling the processing time to fulfill the actual dynamic imaging requirements. As far as we are concerned, the attained prior knowledge and formula could provide strong assistance for underwater polarization imaging.