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222 results on '"Li, Alexander D."'

2. THz Imaging System for in vivo Human Cornea

Author

Sung, Shijun, Selvin, Skyler, Bajwa, Neha, Chantra, Somporn, Nowroozi, Bryan, Garritano, James, Goell, Jacob, Li, Alexander D, Deng, Sophie X, Brown, Elliott R, Grundfest, Warren S, and Taylor, Zachary D

Subjects
Communications Engineering, Engineering, Atomic, Molecular and Optical Physics, Physical Sciences, Biomedical Imaging, Bioengineering, Eye Disease and Disorders of Vision, 4.1 Discovery and preclinical testing of markers and technologies, Detection, screening and diagnosis, Eye, Biological and medical imaging, clinical instruments, medical diagnostics, terahertz (THz) imaging of cornea, THz imaging of cornea, Optical Physics, Electrical and Electronic Engineering, Communications engineering, Atomic, molecular and optical physics
Abstract

Terahertz (THz) imaging of corneal tissue water content (CTWC) is a proposed method for early, accurate detection and study of corneal diseases. Despite promising results from ex vivo and in vivo cornea studies, interpretation of the reflectivity data is confounded by the contact between corneal tissue and rigid dielectric window used to flatten the imaging field. This work develops a novel imaging system and image reconstruction methods specifically for nearly spherical targets such as human cornea. A prototype system was constructed using a 650 GHz multiplier source and Schottky diode detector. Resolution and imaging field strength measurement from characterization targets correlate well with those predicted by the quasioptical theory and physical optics analysis. Imaging experiments with corneal phantoms and ex vivo corneas demonstrate the hydration sensitivity of the imaging system and reliable measurement of CTWC. We present successful acquisition of non-contact THz images of in vivo human cornea, and discuss strategies for optimizing the imaging system design for clinical use.

Published
2018

3. Infantile Myofibromatosis of the Femoral Neck: A Case Report.

Author

Gunderson, Ashlynn, Abraham, Vivek M., Li, Alexander D., Lorimer, Shannon D., and Rocchi, Vanna

Subjects
FEMUR neck, BREECH delivery, CONGENITAL hip dislocation, FEMUR, DYSPLASIA
Abstract

Case: A 15-month-old boy who was being followed for developmental dysplasia of the hip because of breech presentation was discovered to have a solitary infantile myofibroma in the left femoral neck. The patient was avoiding weight-bearing on the affected extremity; thus, stabilization of the femoral neck was performed using a proximal femur locking plate. Postoperatively, he achieved all gross motor developmental milestones. Conclusion: This report is the first to describe a solitary infantile myofibroma in the femoral neck and demonstrates the utility of operative stabilization of these lesions. [ABSTRACT FROM AUTHOR]

Published
2024
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11. Photoswitching between black and colourless spectra exhibits resettable spatiotemporal logic

Author

Wu, Yue, Guo, Zhiqian, Zhu, Wei-Hong, Wan, Wei, Zhang, Junji, Li, Wenlong, Li, Xin, Tian, He, Li, Alexander D. Q., Wu, Yue, Guo, Zhiqian, Zhu, Wei-Hong, Wan, Wei, Zhang, Junji, Li, Wenlong, Li, Xin, Tian, He, and Li, Alexander D. Q.

Abstract

Logic is the key to computing. Traditionally, logic devices have been fabricated by the top-down approach, whose dimensions are drastically limited. The ultimate goal is to use molecular tailorability to design logics using the "bottom-up'' approach. Here we report an unprecedented photochromic molecule that undergoes unimolecular logic switching when excited anywhere in the entire UV-visible spectrum, thus a bottom-up, all-photonic, molecular logic gate. Specifically, these molecular photonic logics embedded in the polymer thin films function as the "AND'' or "OR'' gate at different temporal responses. To achieve high information-processing density, moreover, a ternary flip-flap-flop gate is realized in the molecular logic because the fact that this photochromic molecule can be photoswitched anywhere in its UV-vis spectrum enabled three different lasers (532, 473, and 561 nm) as the inputs to deliver the complex logic optical outputs., QC 20160406

Published
2016
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