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5. Intraoperative Laparoscopic Near-Infrared Fluorescence Cholangiography to Facilitate Anatomical Identification: When to Give Indocyanine Green and How Much.

Author

Zarrinpar, Ali, Dutson, Erik P, Mobley, Constance, Busuttil, Ronald W, Lewis, Catherine E, Tillou, Areti, Cheaito, Ali, Hines, O Joe, Agopian, Vatche G, and Hiyama, Darryl T

Subjects
Humans, Cholecystitis, Indocyanine Green, Cholangiography, Laparoscopy, Monitoring, Intraoperative, Drug Administration Schedule, Prospective Studies, Fluorescence, Patient Selection, Adult, Aged, Aged, 80 and over, Middle Aged, Coloring Agents, Female, Male, Young Adult, biliary anatomy, infrared fluorescence, intraoperative cholangiography, intraoperative guidance, Digestive Diseases, Liver Disease, Clinical Research, Clinical Sciences, Design Practice and Management, Surgery
Abstract

Recent technological advances have enabled real-time near-infrared fluorescence cholangiography (NIRFC) with indocyanine green (ICG). Whereas several studies have shown its feasibility, dosing and timing for practical use have not been optimized. We undertook a prospective study with systematic variation of dosing and timing from injection of ICG to visualization. Adult patients undergoing laparoscopic biliary and hepatic operations were enrolled. Intravenous ICG (0.02-0.25 mg/kg) was administered at times ranging from 10 to 180 minutes prior to planned visualization. The porta hepatis was examined using a dedicated laparoscopic system equipped to detect NIRFC. Quantitative analysis of intraoperative fluorescence was performed using a scoring system to identify biliary structures. A total of 37 patients were enrolled. Visualization of the extrahepatic biliary tract improved with increasing doses of ICG, with qualitative scores improving from 1.9 ± 1.2 (out of 5) with a 0.02-mg/kg dose to 3.4 ± 1.3 with a 0.25-mg/kg dose (P < .05 for 0.02 vs 0.25 mg/kg). Visualization was also significantly better with increased time after ICG administration (1.1 ± 0.3 for 10 minutes vs 3.4 ± 1.1 for 45 minutes, P < .01). Similarly, quantitative measures also improved with both dose and time. There were no complications from the administration of ICG. These results suggest that a dose of 0.25 mg/kg administered at least 45 minutes prior to visualization facilitates intraoperative anatomical identification. The dosage and timing of administration of ICG prior to intraoperative visualization are within a range where it can be administered in a practical, safe, and effective manner to allow intraoperative identification of extrahepatic biliary anatomy using NIRFC.

Published
2016

18. An fMRI investigation of neural activation predicting memory formation in children with fetal alcohol spectrum disorders

Author

Lewis, Catherine E., primary, Thomas, Kevin G.F., additional, Ofen, Noa, additional, Warton, Christopher M.R., additional, Robertson, Frances, additional, Lindinger, Nadine M., additional, Molteno, Christopher D., additional, Meintjes, Ernesta M., additional, Jacobson, Joseph L., additional, and Jacobson, Sandra W., additional

Published
2021
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20. Deficits in arithmetic error detection in infants with prenatal alcohol exposure: An ERP study

Author

Berger, Andrea, primary, Shmueli, Michael, additional, Lisson, Svetlana, additional, Ben-Shachar, Mattan S., additional, Lindinger, Nadine M., additional, Lewis, Catherine E., additional, Dodge, Neil C., additional, Molteno, Christopher D., additional, Meintjes, Ernesta M., additional, Jacobson, Joseph L., additional, and Jacobson, Sandra W., additional

Published
2019
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25. Efficacy of Maternal Choline Supplementation During Pregnancy in Mitigating Adverse Effects of Prenatal Alcohol Exposure on Growth and Cognitive Function: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

Author

Jacobson, Sandra W., primary, Carter, R. Colin, additional, Molteno, Christopher D., additional, Stanton, Mark E., additional, Herbert, Jane S., additional, Lindinger, Nadine M., additional, Lewis, Catherine E., additional, Dodge, Neil C., additional, Hoyme, H. Eugene, additional, Zeisel, Steven H., additional, Meintjes, Ernesta M., additional, Duggan, Christopher P., additional, and Jacobson, Joseph L., additional

Published
2018
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30. Trauma System Overtriage: Are We on Track?

Author

Fullerton, Zoe, primary, Donald, Graham W., additional, Cryer, Henry G., additional, Lewis, Catherine E., additional, Cheaito, Ali, additional, Cohen, Marilyn, additional, and Tillou, Areti, additional

Published
2014
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31. Contributors

Author

Abdelmalak, Basem, Abu-Omar, Yasir, Achilli, Felice, Aguirre-Bermeo, Hernán, Akbari, Ayub, Alarcon, Louis H., Aldo, F. Luke, Al-Khafaji, Ali, Amathieu, Roland, Anderson-Dam, John Leo, Aneja, Rajesh K., Antonelli, Massimo, Antongiorgi, Zarah D., Antoniadou, Anastasia, Anupam, Anupam, Appendini, Lorenzo, Argent, Andrew C., Arnold, John H., Ashwal, Stephen, Astiz, Mark E., Baas, Arnold S., Baldisseri, Marie R., Balogh, Zsolt J., Banerjee, Arna, Bansal, Shweta, Banton, Kaysie, Barie, Philip S., Barjaktarevic, Igor, Bass, Barbara L., Bassi, Gianluigi Li, Bassin, Sarice L., Bastarache, Julie A., Bausch, Daniel G., Bayır, Hülya, Beaulieu, Yanick, Beaver, Thomas M., Beilman, Gregory, Bell, Michael J., Bello, Giuseppe, Benharash, Peyman, Bermeo-Ovalle, Adriana, Bernard, Gordon R., Berry, Cherisse D., Besecker, Beth Y., Bierens, Joost, Biffl, Walter L., Bleck, Thomas P., Bledsoe, Thomas A., Bloch, Karen C., Bohn, Desmond, Boldt, David, Bond, Geoffrey J., Bradshaw, Michael J., Brazzi, Luca, Brimioulle, Serge, Brook, Itzhak, Brundage, Richard C., Burgardt, Sara T., Burroughs, Sherilyn Gordon, Callaway, Clifton W., Calverley, Peter M.A., Camm, John, Campbell, Andre, Cappelletty, Diane M., Carcillo, Joseph A., Chan, Edward D., Chandrashekaran, Satish, Chawla, Lakhmir S., Chen, David C., Chopra, Amit, Clark, Robert S.B., Cohen, Jonathan D., Cohn, Stephen M., Cole, Kelli A., Collins, Staci, Com, Gulnur, Cook, Chris C., Cooney, Robert N., Corbridge, Susan J., Corbridge, Thomas C., Cornely, Oliver A., Crandall, Marie L., Čretnik, Andrej, Crippen, David, Croft, Chasen Ashley, Crouser, Elliott D., Cunha, Burke A., Cunha, Cheston B., Curtis, J. Randall, Dalton, Heidi J., Darby, Joseph M., Davies, John D., Dellavolpe, Jeffrey, De Smet, Anne Marie G.A., Dhillon, Anahat, Dhupar, Rajeev, Dicker, Rochelle A., Muzio, Francesca Di, Diringer, Michael N., Diven, Conrad F., Doelken, Peter, Donahoe, Michael, Boyd, Caron L., Eble, Brian K., Edelstein, Charles L., Edwards, Randolph, Elhassan, Elwaleed A., Ely, E. Wesley, Emlet, Lillian L., Emtiazjoo, Amir, English, Shane W., Ershoff, Brent, Ettinger, Joel H., Ettinger, Josh, Evans, David C., Everson, Gregory T., Faggiano, Chiara, Fair, Jeff, Falk, Ronald J., Farmer, Brenna, Farnan, Rory, Farwell, Alan P., Feild, Carinda, Feller-Kopman, David, Felmet, Kathryn, Ferrer, Miguel, Fink, Ericka L., Fink, Mitchell P., Fortune, Brett E., Freedman, Barry I., Fried, Elchanan, Frimpong, Kwame, Garg, Rajeev K., Gazmuri, Raúl J., Geelkerken, Robert H., Gehr, Todd W.B., Gentile, Michael A., George, M. Patricia, Gerlach, Herwig, Giamarellou, Helen, Ginsberg, Fredric, Gleason, Thomas G., Goerlich, Corbin E., Goodman, Diana J., Gopinath, Shankar, Gorcsan, John, III, Gozal, Yaacov, Gradon, Jeremy D., Graves, Cornelia R., Gregoretti, Cesare, Greinacher, Andreas, Gropper, Michael A., Gubbins, Paul O., Gudzenko, Vadim, Gunnerson, Kyle J., Habib, Fahim A., Harbrecht, Brian G., Harper, Yenal I.J., Hassan, Moustafa, Hazelzet, Jan A., Hiatt, Jonathan R., Hickey, Robert W., Higgins, Thomas L., Hill, Nicholas S., Hiremath, Swapnil, Hladik, Gerald A., Hollenberg, Steven M., Hoste, Eric, Hsu, Albert T., Huang, David T., Huggins, J. Terrill, Hull, Russell D., Ibrahim, Joseph Abdellatif, Ingraham, Angie, Isaac, Margaret L., Isbister, James P., Jacquerioz, Frederique A., Jadhav, Ashutosh P., Jiménez, David, Johannes, Jimmy, Jordan, Janeen Rene, Jorens, Philippe G., Jozwiak, Mathieu, Jung, Rose, Kapoor, Aanchal, Kaufman, David C., Kaynar, A. Murat, Kellum, John A., Kirton, Orlando, Knight, Jason, Kochanek, Patrick M., Koehler, Philipp, Kolkman, Jeroen J., Kollef, Marin H., Korb, Cecilia, Kormos, Robert L., Kornblith, Lucy Z., Košir, Roman, Kotloff, Robert M., Kozar, Rosemary A., Kratzert, Wolf Benjamin, Kumar, Anand, Kvetan, Vladimir, Larson, Shawn D., Lebuffe, Gilles, Lee, Constance, Lee, Hans J., Leung, Angela M., Levi, Allan D., Levin, Phillip D., Levy, Jerrold H., Levy, Mitchell M., Lewis, Anthony J., Lewis, Catherine E., Lewis, Susan J., Liebman, Scott, Linas, Stuart L., Linefsky, Jason P., Link, Kerry Michael, Lipsett, Pamela, Lipshutz, Angela K.M., Lopez-Magallon, Alejandro J., Maas, Andrew I.R., MacIntyre, Neil R., Macrae, Duncan, Madigan, Michael C., Maggiolini, Stefano, Mahajan, Aman, Maisch, Bernhard, Mancebo, Jordi, Mann, Henry J., Manocha, Sanjay, Margulies, Daniel R., Marik, Paul E., Marion, Donald W., Markle, Stephanie, Martinez-Camacho, Alvaro, Mayr, Florian B., Mazariegos, George V., Mazzarelli, Joanne, McGloughlin, Steven A., McIntyre, Lauralyn, McLean, Anna W., McNamara, John F., McNutt, Michelle K., Ponce Mejia, Lucido L., Meldrum, Daniel R., Meltzer, Joseph S., Mesotten, Dieter, Meyer, Kimberly S., Micek, Scott T., Michelson, David J., Mills, Dianne, Mitchell, Bartley, Mittel, Aaron M., Monnet, Xavier, Montford, John, Moore, Frederick A., Moore, Laura J., Moores, Lisa K., Moran, Colleen M., Morris, Alison, Mort, Thomas C., Moss, Michele, Mourvillier, Bruno, Muñoz, Ricardo, Naber, Kurt G., Nair, Girish B., Navarro, Jovany Cruz, New, Melissa L., Nguyen-Lee, Jennifer, Niederman, Michael S., Niven, Alexander S., Ochoa, Juan B., Oddo, Mauro, O'Neill, Patrick J., Opal, Steven M., Orlowski, James P., Otto, Catherine M., Page, Aravinda, Parrillo, Joseph E., Patel, Rohit Pravin, Paterson, David L., Peitzman, Andrew B., Penoyer, Daleen Aragon, Pepe, Judith L., Peters, Steve G., Pilatz, Adrian, Piovesana, Giovanni, Plum, Fred, Polderman, Kees H., Pollack, Murray M., Pollandt, Sebastian, Pronovost, Peter J., Puyana, Juan Carlos, Ra, Jin H., Rainey, Thomas G., Ramsingh, Davinder, Ranganathan, Sarangarajan, Ranieri, V. Marco, Rejai, Sepehr, Reyes, Jorge, Reynolds, Joshua C., Ristic, Arsen D., Robertson, Claudia S., Robin, Emmanuel, Robinson, Todd W., Roche-Campo, Ferran, Romito, Bryan, Rosengart, Matthew R., Rubenfeld, Gordon D., Rubin, Lewis J., Rudolph, Jeffrey A., Rueda, Mario, Ruppel, Randall A., Sadasivan, Santhosh, Saft, Howard L., Saggar, Rajan, Saha, Manish K., Salgado, Juan C., Sanchez-de-Toledo, Joan, Sanghani, Vivek R., Santonocito, Cristina, Sappington, Penny Lynn, Sarko, John, Savel, Richard H., Savelieva, Irina, Schoolwerth, Anton C., Schott, Christopher K., Schrier, Robert W., Schulman, Carl, Seger, Donna L., Selleng, Sixten, Sellke, Frank W., Sethuraman, Kinjal N., Sheridan, Robert L., Shiloh, Ariel L., Singer, Pierre, Singh, Sumit P., Slonim, Anthony D., Sodha, Neel R., Squadrone, Vincenzo, Sreedharan, Roshni, Steinberg, Steven M., Steinhorn, David M., Stocchetti, Nino, Stübgen, Joerg-Patrick, Sucher, Joseph F., Szpilman, David, Teboul, Jean-Louis, Teitelbaum, Isaac, Terragni, Pierpaolo, Thom, Stephen R., Thomas, Elizabeth, Timsit, Jean-Francois, Tisherman, Samuel A., Todd, S. Robert, Tolwani, Ashita J., Torres, Antoni, Turner, Cody D., Turner, Krista, Tzeng, Edith, Vallet, Benoît, Van den Berghe, Greet, van Zanten, Arthur R.H., Vanommeslaeghe, Floris, Venkataraman, Ramesh, Ventre, Kathleen M., Vespa, Paul M., Vincent, Jean-Louis, Wagenlehner, Florian M.E., Wagner, Justin P., Walker, Paul Phillip, Walley, Keith R., Walter, Robert J., Wang, Kevin K.W., Wang, Tisha, Ward, Nicholas S., Ware, Lorraine B., Watson, Gregory A., Wechsler, Lawrence R., Weidner, Wolfgang, Weissman, Charles, Wilcox, Mark H., Wille, Keith M., Wolff, Michel, Wunderink, Richard G., Wybourn, Christopher, Yang, Zhihui, Yarmus, Lonny, Yende, Sachin, Yi, Stephanie Grace, Yu, Dongnan, Yu, Felix, Yusen, Roger D., and Zazulia, Allyson R.

Published
2017
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42. A tactile feedback system for robotic surgery

Author

Culjat, Martin O., primary, King, Chih-Hung, additional, Franco, Miguel L., additional, Lewis, Catherine E., additional, Bisley, James W., additional, Dutson, Erik P., additional, and Grundfest, Warren S., additional

Published
2008
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45. Development and Testing of a Tactile Feedback System for Robotic Surgery.

Author

Westwood, James D., Westwood, Susan W., Haluck, Randy S., Hoffman, Helene M., Mogel, Greg T., Phillips, Roger, Robb, Richard A., Vosburgh, Kirby G., Grundfest, Warren S., Culjat, Martin O., King, Chih-Hung, Franco, Miguel L., Wottawa, Christopher, Lewis, Catherine E., Bisley, James W., and Dutson, Erik P.

Abstract

A tactile feedback system has been developed using silicone-based pneumatic balloon actuators and piezoelectric force sensors, paired with a pneumatic control system. This system has been fitted directly onto the da Vinci surgical robotic system, allowing the forces applied at the robotic end-effectors to be felt on the fingers of surgeons or other system operators. Preliminary system tests have been performed to evaluate the efficacy of the system and to validate the tactile feedback approach. The actuators and pneumatic system had a sufficiently low footprint such that they did not hinder movements during surgical task performance. Preliminary studies using a pressure-indicating phantom suggested that grip force may be reduced with direct tactile-to-tactile feedback. An additional study found that a six element tactile sensing array can effectively provide spatial information to the fingers. The results of these studies are summarized in this paper. [ABSTRACT FROM AUTHOR]

Published
2009

46. Abundant years: An Elizabeth Spencer checklist, 1976 to 1992.

Author

Lewis, Catherine E.

Subjects
*BIBLIOGRAPHY
Abstract

Presents a bibliography of works by and about author Elizabeth Spencer. Career background; Categories; Works include `The Salt Line,' by Elizabeth Spencer; `Blurbs: Welty on Spencer,' by W.U. McDonald; `The Centrality of Personal Memory,' by Dan Pope.

Published
1994

47. The Literature of Spanish South America : Its Background, Development and Characteristics

Author

Lewis, Catherine E. and Lewis, Catherine E.

Abstract

The scope of this work is to be confined to those nations on the continent of South America which use as their national tongue the Spanish language. This excludes consideration of Brazil, whose language is Portuguese and which possesses a rich literature of its own. Another country is omitted, Paraguay, not from oversight, but because this inland republic is so backward in culture and development that it possesses nothing which can be dignified with the term national literature. Argentina, Uruguay, Chile, Peru, Bolivia, Ecuador, Colombia, and Venezuela - these are the countries of Spanish America with which this discussion will be concerned.

Published
1936

49. Development and testing of a tactile feedback system for robotic surgery.

Author

Grundfest WS, Culjat MO, King CH, Franco ML, Wottawa C, Lewis CE, Bisley JW, and Dutson EP

Subjects
Equipment Design, Humans, Silicones, User-Computer Interface, Feedback, Robotics instrumentation, Sensory Aids, Surgery, Computer-Assisted instrumentation, Touch
Abstract

A tactile feedback system has been developed using silicone-based pneumatic balloon actuators and piezoelectric force sensors, paired with a pneumatic control system. This system has been fitted directly onto the da Vinci surgical robotic system, allowing the forces applied at the robotic end-effectors to be felt on the fingers of surgeons or other system operators. Preliminary system tests have been performed to evaluate the efficacy of the system and to validate the tactile feedback approach. The actuators and pneumatic system had a sufficiently low footprint such that they did not hinder movements during surgical task performance. Preliminary studies using a pressure-indicating phantom suggested that grip force may be reduced with direct tactile-to-tactile feedback. An additional study found that a six element tactile sensing array can effectively provide spatial information to the fingers. The results of these studies are summarized in this paper.

Published
2009

50. A tactile feedback system for robotic surgery.

Author

Culjat MO, King CH, Franco ML, Lewis CE, Bisley JW, Dutson EP, and Grundfest WS

Subjects
Biomedical Engineering, Biophysics, Equipment Design, Feedback, Humans, Touch, Robotics instrumentation, Surgery, Computer-Assisted instrumentation
Abstract

A tactile feedback system was developed and mounted on the da Vinci robotic surgical system. The system features silicone-based tactile balloon actuators mounted on the robotic master controls, modified commercial piezoresistive sensors mounted on the robotic end effectors, and a pneumatic control system. The system has a frequency response of up to 20 Hz, a linear input force-output pressure relationship, and provides five discrete levels of actuation over a force input range of 0 to 25 N. A demonstration of the system with four subjects grasping a phantom with an embedded pressure-sensitive film suggested that less force was applied with tactile feedback. This paper describes the design, fabrication, characterization, and demonstration of the mounted tactile feedback system and its components. Ongoing studies using the system will assess the benefit of tactile stimuli to learning and control in robotic surgery.

Published
2008
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