171 results on '"Lessinger, Jean-Marc"'
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2. COVID-19 promotes endothelial dysfunction and thrombogenicity: role of proinflammatory cytokines/SGLT2 prooxidant pathway
- Author
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Mroueh, Ali, Fakih, Walaa, Carmona, Adrien, Trimaille, Antonin, Matsushita, Kensuke, Marchandot, Benjamin, Qureshi, Abdul Wahid, Gong, Dal-Seong, Auger, Cyril, Sattler, Laurent, Reydel, Antje, Hess, Sébastien, Oulehri, Walid, Vollmer, Olivier, Lessinger, Jean-Marc, Meyer, Nicolas, Pieper, Michael Paul, Jesel, Laurence, Bäck, Magnus, Schini-Kerth, Valérie, and Morel, Olivier
- Published
- 2024
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3. COVID-19 exposure in SARS-CoV-2-seropositive hospital staff members during the first pandemic wave at Strasbourg University Hospital, France
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Velay, Aurélie, Gallais, Floriane, Wendling, Marie-Josée, Bayer, Sophie, Reix, Nathalie, Schneider, Anne, Glady, Ludovic, Collongues, Nicolas, Lessinger, Jean-Marc, Hansmann, Yves, Kling-Pillitteri, Laurence, De Sèze, Jérome, Gonzalez, Maria, Schmidt-Mutter, Catherine, Meyer, Nicolas, and Fafi-Kremer, Samira
- Published
- 2022
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4. Evolution of antibody responses up to 13 months after SARS-CoV-2 infection and risk of reinfection
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Gallais, Floriane, Gantner, Pierre, Bruel, Timothée, Velay, Aurélie, Planas, Delphine, Wendling, Marie-Josée, Bayer, Sophie, Solis, Morgane, Laugel, Elodie, Reix, Nathalie, Schneider, Anne, Glady, Ludovic, Panaget, Baptiste, Collongues, Nicolas, Partisani, Marialuisa, Lessinger, Jean-Marc, Fontanet, Arnaud, Rey, David, Hansmann, Yves, Kling-Pillitteri, Laurence, Schwartz, Olivier, De Sèze, Jérome, Meyer, Nicolas, Gonzalez, Maria, Schmidt-Mutter, Catherine, and Fafi-Kremer, Samira
- Published
- 2021
- Full Text
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5. COVID-19 promotes endothelial dysfunction and thrombogenicity: role of proinflammatory cytokines/SGLT2 prooxidant pathway
- Author
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Mroueh, Ali, primary, Fakih, Walaa, additional, Carmona, Adrien, additional, Trimaille, Antonin, additional, Matsushita, Kensuke, additional, Marchandot, Benjamin, additional, Qureshi, Abdul Wahid, additional, Gong, Dal-Seong, additional, Auger, Cyril, additional, Sattler, Laurent, additional, Reydel, Antje, additional, Hess, Sébastien, additional, Oulehri, Walid, additional, Vollmer, Olivier, additional, Lessinger, Jean-Marc, additional, Meyer, Nicolas, additional, Pieper, Michael Paul, additional, Jesel, Laurence, additional, Bäck, Magnus, additional, Schini-Kerth, Valérie, additional, and Morel, Olivier, additional
- Published
- 2023
- Full Text
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6. Clinical features and prognostic factors of listeriosis: the MONALISA national prospective cohort study
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Hausfater, Pierre, Pourriat, Jean-Louis, Casalino, Enrique, Riou, Bruno, Pateron, Dominique, Yéni, Patrick, Bricaire, François, Ville, Yves, Azria, Elie, Dommergues, Marc, Bergmann, Jean-François, Wolff, Michel, Mira, Jean-Paul, Guillevin, Loïc, Zuber, Mathieu, Abasse, Soumeth, Aberrane, Saïd, Abgueguen, Pierre, Abokasem, Ayman, Abraham, Bruno, Ache-Papillon, Chantal, Adam, Pascal, Adam, Marie-Noëlle, Adhoute, Xavier, Adoue, Daniel, Afi, Moncef, Afroukh, Nawel, Agha-Mir, Ilhem, Aissa, Nejla, Aissaoui, Liamine, Akerman, Grégory, Akkari, Ali, Al Chaar, Majed, Al Freijat, Faraj, Al-Jalaby, Bachar, Albert, Didier, Albertini, Marie-Thérèse, Albinet, Hélène, Alfonsi, Gwenaël, Ali, Youssef, Chaouche, Zahr-Eddine Ali, Allart, Anne, Alric, Laurent, Améri, Alain, Amoura, Zahir, Ampère, Alexandre, Amroun, Hakim, Ananivi, Amévi, Ancelin, Pascal, André, Thierry, Andremont, Antoine, Andreotti, Dominique, Andriamaneo, Hélinoro, Andriau, Clara, Anglaret, Hélène, Anguel, Nadia, Annaix, Véronique, Anteur, Wassila, Anuset, Delphine, Aoudia, Ourida, Arabi, Miloud, Archambaud, Muriel, Archambaud, Maryse, Ardiet, Emmanuel, Argaud, Laurent, Arista, Sophie, Arlet, Guillaume, Armengaud, Jean, Arnal, Jean-Michel, Arnault, Isabelle, Arsène, Olivier, Assaf, Ziad, Assi, Assi, Assouline, David, Astruc, Dominique, Aubard, Yves, Aubert, Claude, Aubry, Jean-Paul, Auburtin, Marc, Aucher, Philippe, Audeguy, Philippe, Audié, Jean-Pierre, Aumaitre, Hugues, Aumersier, Michel, Auroux, Jean, Autret, Fanny, Auvray, Etienne, Ayach, Badih, Aye, Paul, Ayouz, Khélifa, Bachelier, Marie-Nadège, Badia, Thomas Bachelot Philippe, Badila, Patrice, Bador, Julien, Badurescu, Viorica, Baldesi, Olivier, Bandaly, Françoise, Bandin, Olivia, Bani-Sadr, Firouzé, Bannier, Stéphanie, Baranger, Thierry, Barazer, Isabelle, Barbier, Marie-Christine, Barbier, François, Barbier, Carole, Barbieux, Marianne, Marie, Barboteau, Annick, Barbut, Patricia, Baret, Mylène, Barière, François, Baril, Jean-Yves, Barillot, Isabelle, Barjon, Geneviève, Barnaud, Guilène, Barraduc, Régine, Barraud, Francis, Barraud, Olivier, Barre, Eric, Barrelet, Audrey, Barrier, Jocelyn, Bart, Fréderic, Barthélémy, Gérard, Baty, Gaëlle, Baud, Olivier, Baudel, Jean-Luc, Bay, Jacques-Olivier, Bay, Jérôme, Bazin, Claude, Beague, Sébastien, Beal Ardisson, Dominique, Beaune, Bertrand, Beauplet-Lepage, Anne, Bébéar, Cécile, Bechade, Dominique, Becherrawy, Céline, Becker-Schneider, Michelle, Bednarek, Nathalie, Bedock, Bernard, Begon, Edouard, Bekguesmia, Zaineb, Belaisch-Amart, Joëlle, Belhadj, Karim, Belle, Evelyne, Belmonte, Olivier, Belot, Jean-Pierre, Bemrah, Abdelkader, Ben Soltana, Mouna, Benbara, Amélie, Benddif-Fin, Faiza, Bénézit, François, Benifla, Jean-Louis, Benjelloul, Amine, Benkaci, Yacine, Benkhelil, Abdelaziz, Benoit-Cattin, Thierry, Benoit-Coustou, Sophie, Bensadoun, René-Jean, Bensaid, Thierry, Jacques Bensaude, Raoul, Bérard, Henri, Bercot, Béatrice, Berdin, Bruno, Berger, Marc, Berger, Pierre, Bergheul, Smail, Bergues, Benoît, Berland, Yvon, Bernard, Claude, Bernard, Louis, Bernardaud, Bérangère, Bernardi, Franck, Bernardin, Gilles, Bernasconi, François, Bert-Marcaz, Patrick, Berteaux, Béatrice, Berth-Farges, Anne, Berthelot, Gilles, Berthet, Jean, Bertrand, Kevin, Bertrou, Anne, Besnard, Marianne, Bessede, Emilie, Bethery, Philippe, Beuscart, Claude, Beyne-Rauzy, Odile, Beytout, Jean, Bezian, Marie-Christine, Bicais, Brigitte, Bidart, Sabine, Bidault, Christian, Biessy, Hélène, Bigot, Pierre, Bildea, Adrianna, Bille, Emmanuelle, Billy, Christophe, Biron, Nathalie, Bizet, Jérôme, Blaise, Didier, Blaise, Agathe, Blaison, Gilles, Blaka, Mariam, Blanc, Pierre, Blanc, Stéphane, Blanc-Amrane, Véronique, Blanchard, Pierre, Blanchard-Marche, Geneviève, Blancs, Michèle, Blazejewski, Caroline, Bléher, Yves, Blewoussi, Koffi, Blondet, Romain, Blot, François, Blum, Georges-Fabrice, Bodson, Lucien, Boidin, Emilie, Boileau, Julien, Boileau, Pascal, Boin-Gay, Véronique, Boisseau, Martial, Boisselier, Christine, Bollaert, Pierre-Edouard, Bolot, Pascal, Bonacorsi, Stéphane, Bonfils, Marie, Bonitchi, Pascal, Bonnan, Mickael, Bonnefoy, Philippe, Bonnet, Delphine, Bonnet, Richard, Bonnin, Emmanuelle, Bor, Jacques, Borie, Marie-Françoise, Borstein, Bernard, Bossi, Philippe, Botreau, Yves, Bottero, Julie, Bouasria, Abderrezak, Bouaziz, Radia, Bouchaud, Olivier, Bouche, Flore, Bouchet, Gérard, Bouden, Vincent, Boudhane, Amar, Boudy, Carole-Anne, Boue, François, Bouet, Cédric, Claude Boufetteau, Jean, Bouffandeau, Bernard, Bouhour, Damien, Bouiller, Marc, Bouillet, Laurence, Bouissou, Antoine, Boulain, Luc, Bourgeois, Stéphane, Bourgerette, Evelyne, Bourlet, Anne, Bourlière, Marc, Bourrée, Thomas, Bourrouillou, Aude, Boussekey, Nicolas, Boussier, Remi, Boutoille, David, Bouyer, Jean-Luc, Bouyssou-Destriau, Denise, Bouziges, Nicole, Boyer, Michelle, Braem, Louis, Branger, Bernard, Branger, Catherine, Brasme, Lucien, Bray, Philippe, Brazille, Patricia, Bresson, Violaine, Bret, Laurent, Breton, Anne-Laure, Breuil, Jacques, Brevet, Françoise, Briaud, Michel, Bridoux, Delphine, Briend, Delphine, Briere, Anne-Isabelle, de la Hosseraye, Claire Briere, Brieu, Nathalie, Brieux, Jean-Philippe, Brihier, Hélène, Brisou, Patrick, Brival, Marie-Laure, Broche, David, Brochen, Joëlle, Bron, Camille, Bronet, Nathalie, Bronner, Jacques, Bronowicki, Jean-Pierre, Brosset, François, Brottier-Mancini, Elisabeth, Brovedani, Sophie, Bruley des Varannes, Stanislas, Brunel, Pascale, Brunet, Patrick, Brunet, Xavier, Brunet, Stéphanie, Brung-Lefebvre, Maud, Brunot, Vincent, Brusset, Alain, Burc-Struxiano, Laurence, Burdin, Michèle, Bureau, Thierry, Buron, Fanny, Burucoa, Christophe, Cabalion, Jean, Cabasson, Severine, Cabié, André, Cacheux, Victoria, Cadiergue, Vincent, Cadiot, Guillaume, Caille, Vincent, Cailleaux Pierre-Etienne Cailleux, Vincent, Caillon, Jocelyne, Caillot, Denis, Camara, Mohamed, Cambau, Emmanuelle, Cambonie, Gilles, Camiade, Sabine, Canis, Frederique, Canitrot, Meriem, Canu, Nathalie, Capellier, Gilles, Carbillon, Lionel, Carbonelle, Bernard, Carbonelle, Etienne, Carboni, Marion, Carbonne, Bruno, Carcenac, Francis, Cardot, Florence, Carette, Sylvie, Cariou, Sylvie, Carli, Pierre, Carmagnol, Françoise, Caroli-Bosc, François-Xavier, Caron, François, Cartron, Guillaume, Casali, Patrick, Casanovas, Olivier, Cassignard, Dominique, Castaing, Denis, Castel, Brisse, Castelin, Sandrine, Castelnau, Pierre, Cathebras, Pascal, Catineau, Jean, Catteu, Sylviane, Cattier, Blandine, Cattoen, Christian, Cattoir, Vincent, Caumes, Eric, Caussin, Jean, Cavalié, François, Ceppa, Franck, Cerf, Charles, Ceriez, Anne, Cervantes, Nathalie, Chabanon-Pouget, Bruno, Chabrol, Amélie, Chachaty, Elisabeth, Chahtour, Hanen, Chaix, Fabrice, Challier, Marion, Chalvon-Demersay, Arnaud, Chambreuil, Guy, Chaminade, Bruno, Chamouine, Abdourahim, Chandesris Joséphine Chapalain-Cagnon, Christine, Chapelle, Alain, Chaplain, Chantal, Chapuzet, Claire, Charachon, Sylvie, Charasse, Christophe, Charbonnier, Thierry, Charlier, Franck, Chassin, Olivier, Chassy, Véronique, Chatellier, Delphine, Chatron, Marlène, Chaussade, Hélène, Chavanet, Pascal, Chavel, Pascale, Chekroun, Ali, Chelle, Wladimir, Chelly, Jonathan, Cherlet, Christel, Chevailler, Alain, Chevalet, Pascal, Chevalier, Yannick, Chidiac, Christian, Chimot, Loïc, Chiouk, Nabil, Chiron, Philippe, Chirouze, Catherine, Chopin, Marie-Charlotte, Choukroun, Gabriel, Chouraqui, Martine, Chraibi, Kamilla, Chudersky, Dominique, Chuzeville, Michel, Cingotti, Michel, Cinquetti, Gael, Ciocan, Dragos, Citony, Isabelle, Claise, Catherine, Clarissou-Philippe, Juliette, Claude, Benoît, Clave, Danielle, Clément, Christophe, Climas, Marie-Thérèse, Coetmeur, Daniel, Cognet, Stéphanie, Cohen, Daniel, Coignard, Sophie, Coindre, Jean-Philippe, Coint, Raphaël, Colamarino, Renato, Colingorski, Anne-Marie, Collard, Olivier, Collet, Michel, Collignon, Anne, Collus, Marie-José, Colombani, Jean-Claude, Colombat, Philippe, Combe, Christian, Condominas, Philippe, Conroy, Marie-Chrsitine, Constans, Thierry, Constantin, Nicole, Contamin, Claudine, Corberand, Damien, Cordier, Anne-Marie, Cordonnier, Charlotte, Corneloup, Hélène, Costa, Yannick, Costa, Frédérique, Coste, Mathieu, Costes, Corinne, Cotes, Françoise, Cotteret, Rabea, Couderc, Louis-Jean, Cougoul, Pierre, Coulaud, Jean-Michel, Coulhon, Marie-Pierre, Coulon, Patrice, Courcol, René, Courillon, Florence, Courjon, Johan, Courouble, Jérémie, Courouge-Dorcier, Dominique, Courtade, Henri, Courtois, Stéphanie, Couturier, Pascal, Créange, Alain, Cremet, Lise, Cremniter, Julie, Croize, Jacques, Crombe, Valérie, Croquet, Ingrid, Cua, Eric, Cufi, Marie-Noelle, Cuvillier, Patrice, Dabysing, Marie-Françoise, Dadoun, Karim, Dagada, Corinne, Dahan, Sonia, Dahoumane, Redouane, Daleas, Jacques, Dallay, Dominique, Dalle, Benoît, Damage, Alexandre, Damaj, Lena, Damaj Gandhi, Laurent, Danalaché, Ana, Danin, Pierre-Eric, Danjean, Marie-Pierre, Danquechin Dorval, Etienne, Dao, Anne, Daoud, Patrick, Darchen, Olivier, Dargère, Sylvie, Darre, Bincy, Dassant, Damien, Dassieu, Gilles, Dattin-Dorrière, Valérie, Daupin, Cedric, Daurel, Claire, Dausset, Jean-Claude, Daval Cote, Mélanie, David, Gary, Davido, Benjamin, De Barbeyrac, Bertille, De Biasi, Michel, De Boysson, Hubert, De Clareuil, Edith, De Kermadec, Jean-Michel, De Martino, Sylvie, De Tayrac, Renaud, De Varax, Roland, De Witte, Sten, Debernardi, Anne, Deboutin, Jean-Luc, Debouverie, Marc, Decoene, Christophe, Decoster, Anne, Decousser, Jean-Winoc, Decré, Dominique, Defebvre, Renaud, Degand, Nicolas, Degreff, Jean-Marc, Deiber, Michel, Delaby, Hélène, Delacour, Thierry, Delahaye, Arnaud, Delarbre, Jean-Marie, Delasalle, Chantal, Delbrouck, Claire, Delecalle, Jean-Gilles, Delesalle, Sophie, Delesalle, Chantal, Delhoustal, Laurence, Deligne, Delphine, Delisle Mizon, Françoise, Delobel, Pierre, Delour, Pierre, Delpeuch, Bruno, Demachy, Marie-Claude, Demarchi, Martin, Demarcq, Marie-Joelle, Demontclos, Henri, Dengo, Jean-Christophe, Deprecq, Sophie, Dequin, Pierre-François, Dereeper, Olivier, Deroux, Alban, Derragui, Aicha, Desblache, Julien, Desbois-Nogard, Nicole, Descamps, Dominique, Descamps, Jean-Michel, Deschamps, Christophe, Deschamps, Jacques, Desemerie, Franck, Desfrere, Luc, Desliers, Joelle, Desnoulez, Laurence, Desplaces, Nicole, Després, Nicolas, Dessin, Jean-François, Destors, Marie, Detante, Olivier, Detave, Mathieu, Detourmignies, Laurence, Devaud, Edouard, Devaux, Yves, Devaux, Bruno, Devianne, François, Devidas, Alain, Devos, Philippe, Dewitte, Camille, Dewulf, Gisèle, Dhennain, Chantal, Di Meglio, Chloé, Diallo, Habiboulaye, Diamantis, Sylvain, Dib, Baihas, Didier, Jean-Marc, Dillies, Anne-Françoise, Dingremont, Claire, Djafari, Noureddine, Djeffal, Abdelmajid, Djerad, Hama, Dollon, Christophe, Doloy, Alexandra, Domart, Yves, Donay, Jean-Luc, Dopeux, Loïc, Dorr, Gaelle, Doucet Populaire, Florence, Dournon, Nathalie, Dreyfus, Michel, Dreyfuss, Didier, Du Cheyron, Damien, Dubois, Elodie, Dubois, Nicolas, Dubosc-Marchenay, Nadine, Dubourdieu, Béatrice, Dubroca, Nadine, Dubus, Jean-Christophe, Duche, Catherine, Duchene, Francis, Dudeffant, Patrick, Duez, Jean-Marie, Duhaut, Pierre, Duluc, Françoise, Dumouchel, Hélène, Dumoulard, Bruno, Dupin, Clarisse, Dupon, Michel, Dupont, Mathieu, Dupont, Damien, Dupont, Patrick, Dupre-Narlet, Emmanuelle, Dupretz, Peggy, Dupuy, Claire-Antoinette, Durand, Michel, Durand, Annie, Durliat-Ellie, Solène, Durox, Hélène, Dussopt, Christine, Dutasta, Fabien, Duval, Véronique, Dzeing, Ella, Eboue, Florence, Ede, Cyrille, Eid, Hanna, El Yamani, Abderrazak, Elbez, Annie, Eldeghedy, Mohamed, Elena-Daumas, Martine, Elhadad, Simon, Elharie-Heraux, Zoubida, Eloy, Clarence, Emeriau, Marie-Etiennette, Emond, Jean-Philippe, Equy, Véronique, Erena-Penet, Anne-Sophie, Esnault, Cecilia, Esposito, Laure, Essouri, Sandrine, Estépa, Laurence, Estève, Vincent, Etchemendy, Sabine, Ettahar, Nicolas, Eustache, Marie-Line, Evillard, Mathieu, Evreux, Françoise, Eychene, Jean-Marc, Eyer, Didier, Eymerit, Philippe, Fabre, Jean-Luc, Fabre, Claire, Faibis, Frédéric, Falchero, Lionel, Falguières, Odile, Fallouh, Hassan, Fanjaud, Nicolas, Fantin, Bruno, Farah, Ibrahim, Farto-Bensasson, Fernanda, Fauchais, Anne-Laure, Fauchart, Jean-Pierre, Faucher, Anna, Faucheux, Jean-Marc, Faudon-Gibelin, Anne, Faurie, Pierre, Fèbre, Claudine, Feddal, Toufik, Ferhat Carre, Assia, Ferreira-Maident, Nicole, Ferreyra, Milagros, Ferroni, Agnès, Ferry, Tristan, Feugier, Pierre, Feugier, Jean-Claude, Fezoui, Hacene, Fiette, Hélène, Fille, Alexandra, Filloux, Jean-Michel, Fily, Fabien, Fines, Marguerite, Fissore Magdelein, Cristel, Flahault, Mathilde, Floriot, Christian, Foguem, Clovis, Fonsale, Nathalie, Fontenel, Benoît, Forest, Anne-Marie, Forest, Anne, Forestier, Emmanuel, Fortin, Louise, Fortineau, Nicolas, Fos, Marie-Pierre, Foucart, Saskia, Fouilhoux, Alain-Charles, Fournel, Pierre, Fournier, Damien, Fourrier, François, Fraisse, Thibaut, Fredenucci, Isabelle, Fremin-Batteux, Odile, Frey, Janine, Frimat, Luc, Froidure, Marie, Fruchart, Christophe, Fruleux, Nathalie, Fuhrmann, Christine, Fuillet, Michel, Funakoshi, Nathalie, Fur, Alain, Gabez-Therou, Patricia, Gaborieau, Valerie, Gabriel-Soléan, Sylvie, Gachassin, Laurence, Gaide, Jean-François, Gaillard, Julia, Gaillard, Jean-Louis, Gaillart, Tiphaine, Gaizi, Sad, Gallo, Nicolas, Gameiro, Manuel-Luis, Garandeau, Caroline, Garbi, Aurelie, Garcera, Yves, Gardes, Ghislaine, Garesslin, Olivier, Garnier, Fabien, Garofano, Marie, Garosi, Olivier, Garre, Michel, Garrec, Hélène, Garrigues, Bernard, Gaschet, Anne, Gascon, Alexandre, Gascou, Emmanuel, Gasnault, Jacques, Gatfosse, Marc, Gattault, Jean-François, Gatti, Hélène, Gauche, Bernard, Gaudard, Philippe, Gaudelus, Joel, Gaudry, Stéphane, Gauduchon, Valérie, Gaulthier, Jean-Baptiste, Gauthier, Yvan, Gebeile, Rémi, Geffray, Loïc, Geffroy, Françoise, Geissler, Alain, Gelez, Maud, Gendrin, Vincent, Gengembre, Guy, Gentilhomme, Hervé, Gérart Pons, Sandrine, Germain, Marie-Claude, Gesquière, Julien, Ghedira, Adel, Ghevaert, Christine, Gillot, Jean-Michel, Girard, Edouard, Girard, Serge, Girard, Pierre-Marie, Girard-Buttaz, Isabelle, Giraud, Martine, Glorieux, Isabelle, Goburdhun, Chandrah, Godin, Michel, Godon, Catherine, Goehringer, François, Goffart, Sylvie, Goidin, Isabelle, Goldgran Toledano, Daniele, Golfier, François, Goll, Armand, Gontieron, Olivier, Goquelin, Anne, Got, Laurence, Goudeau, Alain, Goujard, Cécile, Goupil, François, Gouraud, François, Gourlaouen, Alain, Gournay, Jérôme, Goustille, Julien, Goux, Alain, Grandclerc, Benoît, Grange, Jean-Didier, Granger, Thierry, Granier, Françoise, Granier, Michèle, Grasset, Denis, Gravet, Alain, Grawey, Isabelle, Greder Belan, Alix, Grelaud, Jean-Jacques, Grenet, Karine, Gressier, Bernard, Grignon, Bernadette, Grimprel, Emmanuel, Grise, Geneviève, Grobost, Vincent, Gross Goupil, Marine, Grossi, Olivier, Gruffat, Brigitte, Gruson, Anne, Guénard, Yves, Guérard, Arnaud, Guérin, Bruno, Guérin, Mathilde, Guérin, Claude, Guerquin, Bernard, Guerrot, Dominique, Guéry, Benoît, Gueudet, Philippe, Gueugniaud, Pierre-Yves, Guichard, Isabelle, Guichart, François, Guiden, Ozel, Guider, Bertrand, Guillarmé Grossmann, Pascale, Guillemot, François, Guillet, Pierre, Guillet-Caruba, Christelle, Guillois, Bernard, Guilloy, Olivier, Guimard, Thomas, Guimard, Karine, Guimier, Philippe, Guinard, Jérôme, Guinet, François, Guisset, Olivier, Guitteaud, Karine, Gutmann, Laurent, Guyetand, Severine, Haccourt, Fabian, Hacot, Jean-Pierre, Hadou, Tahar, Haiat, Stéphanie, Haioun, Corinne, Hajjar, Mostapha, Hamitou, Zakaria, Hammami, Sarah, Hamon-Charles, Sophie, Hamou-Plotkine, Laurence, Hanouz, Jean-Luc, Harbi, Samia, Harlé, Jean-Robert, Haro, Sophie, Harou, Christian, Harvey, Thierry, Hatem, Ghada, Hausermann, Marie-Hélène, Hauss, Pierre-Alexandre, Hayoun, Fabrice, Hecham, Moussa, Heches, Xavier, Hedjem, Nourredine, Heidt, Anne, Heisel, Nicolas, Heluwaert, Fréderic, Helvadjian, Thierry, Henni, Tawfiq, Henry-Andrieu, Yanne, Hequet, Delphine, Herbecq, Patrick, Herbrecht, Raoul, Hernu, Romain, Herry, Catherine, Herry, Jean-Paul, Herson, Serge, Heurtaux, Marie-Noelle, Heusse, Emmanuelle, Heyraud-Blanchet, Catherine, Hichri, Yoar, Hilbert, Gilles, Hili, Marie-Thérèse, Hiret, Sandrine, Hittinger, Gilles, Hochart, Anne-Cécile, Hodee, Nathalie, Holstein, Anne, Hombrouk-Alet, Cécile, Hominal, Stéphane, Honderlick, Patrick, Honoré Bouakline, Stéphanie, Hory, Bernard, Hourdebaigt-Larrusse, Pierre, Houssaye, Serge, Houssiaux-Maisonneuve, Nathalie, Hrichi, Abdelkader, Hubert, Didier, Huc, Benoît, Humbert, Karine, Hurel, Dominique, Husson-Wetzel, Stéphanie, Hutin, Pascal, Huttin, Bernard, Hyerle, Laura, Iacobelli, Silvia, Ilunga, Serge, Imbert, Guenièvre, Jabre-Sikias, Elias, Jacob, Jean-Louis, Jacobs, Romain, Jacomy, Dominique, Jacquier, Pascal, Jacquier, Hervé, Jaffarbandjee, Marie-Christine, Jamet, Angéline, Jan, Didier, Jang, Guyro, Jaouen, Anne-Christine, Jardel, Henry, Jarlier, Vincent, Jarrige, Luc, Jarrousse, Bernard, Jauhlac, Benoît, Jault, Véronique, Jault, Thierry, Jaunait, Eric, Javouhey, Etienne, Jean, Rodolphe, Jean, Julie, Jean-Pierre, Hélène, Jeanmaire, Eliette, Jeannot, Katy, Jeddi, Hassen, Jego, Mickael, Jennane, Selim, Join-Lambert, Olivier, Joly, Pascal, Jonquet, Olivier, Josien, Eric, Jouatte, Fabienne, Jouffret, Agnès, Jourde-Chiche, Noémie, Jourdes, Emilie, Jouvencel, Philippe, Jouzel, Charlotte, Julienne, Geneviève, Jullian, Eric, Juven, Agnès, Juvin, Philippe, Kaidomar, Michel, Kaiser, Thomas, Kalfon, Pierre, Kaltenbach, Georges, Kamar, Nassim, Kansau, Imad, Kara, Ali, Karaoui, Leila, Karirisi, Apollinaire, Karkous, Bernard, Kassis, Marie, Kayal, Samer, Keller, Marie, Kemenar, Chrystelle, Kennouche, Samir, Kerchache, Aissa, Kerleau, Jean-Marc, Kervegant, Anne-Gaelle, Khalifa-Thellier, Sandrine, Radhouane-Khanjari, Fethi, Kherouf, Hakim, Khodeir, Nordine, Kibbrecht, Eric, Kim, An, Kisterman, Jean-Paul, Kittschke, Bernard, Klapczynski, Frédéric, Kodzin, Marie-José, Konate, Bano, Kouaho, Sylvain, Koulmann, Laurence, Krechiem, Karim, Kubab, Sarah, Kubiak, Charles, Kurtz, Jean-Emmanuel, Labadie, Philippe, Labarrière, Damien, Labaune-Kiss, Andrea, Labé, Aurélie, Labourdette, Isabelle, Labrousse, Philippe, Labussière, Anne-Sophie, Lachenal, Florence, Lacroix, Jérôme, Lafeuillade, Alain, Lafforgue, Marie-Odile, Lafon, Ingrid, Lagasse, Jean-Pierre, Lagrandeur, Julien, Lalot, Jean-Marc, Lalu, Mélissa, Laluque, Simone, Lamache, Sébastien, Lamarca, Richard, Lamberet, Aurore, Lambert, Thierry, Lambiotte, Fabien, Lamia, Bouchra, Lamoine-Gimet, Ghislaine, Lamour, Armelle, Lamy, Brigitte, Lanba, Patrice, Landgraf, Nathalie, Landraud, Luc, Laporte, Jean-Patrick, Larible, Claire, Larrazet, Fabrice, Larroche, Claire, Lasbasses, Claudine, Lassel, Ludovic, Lassere, Bertrand, Laudat, Patrice, Lauque, Dominique, Laurens, Etienne, Laurent, Frédéric, Lauretta, Raphael, Laurin, Max, Lauzanne, Brigitte, Lavalard, Emmanuelle, Lavenu, Isabelle, Lavigne, Jean-Philippe, Le Baron, François, Le Berre, Rozenn, Le Berruyer, Pierre-Yves, Le Bideau, Marc, Le Boterff, Cécile, Le Chevallier, Sylvain, Le Coustumier, Alain, Le Du, Anne, Le Goff, Valérie, Le Henaff, Catherine, Le Lay, Geneviève, Le Maout, Gilles, Le Pierres, Athéna, Le Pimpec, Patricia, Le Poulain, Marguerite, Le Reste, Anne-Marie, Le Sec, Ludovic, Le Turdu, Françoise, Leautez-Nainville, Sophie, Lebas, Eddy, Leblond, Véronique, Lebreton, Marie-Annick, Lebreton, Didier, Lecaillon-Thibon, Evelyne, Lechat, Sylvie, Lechiche, Catherine, Lecis, Alain, Leclercq, Roland, Lecomte, Claire, Lécuyer, Hervé, Ledru, Sylvie, Leduc, Dominique, Leflon, Véronique, Lefort, Christine, Lefranc, Hélène, Lefrant, Jean-Yves, Legendre, Christophe, Legoff, Isabelle, Legout, Laurence, Legrand, Mathieu, Legras, Annick, Legros, Antoine, Leguen, Virginie, Leibinger, Franck, Lelièvre, Jean-Daniel, Lellouche, Franck, Lemaignen, Adrien, Lemarie, Romain, Lemble, Chantal, Lemenand, Olivier, Lemercier, Fanny, Lemery, Didier, Lemmens, Bruno, Lemyze, Malcolm, Leneveu, Michel, Léonetti, Françoise, Léonnet, Caroline, Léotard, Sophie, Lepeletier, Didier, Lepelletier, Didier, Lepeule, Raphael, Lepiller, Quentin, Lequen, Laurence, Leroux, Lionel, Leroux, Stéphane, Leroy, Hélène, Leroy, Vincent, Leroy, Olivier, Lesage, Fabrice, Lescat, Mathilde, Lesecq, Ludovic, Lessene, Aude, Lessinger, Jean-Marc, Letellier, Claire, Letellier, Nicolas, Letouzey, Vincent, Letranchant, Lorraine, Levast, Marion, Leveneur, Yann, Levent, Thierry, Levy, Marie, Levy, Marc, Leysenne, David, Libeau, Benoît, Likose, Ebutu, Lima, Suzanne, Lina, Gérard, Lioger, Bertrand, Lionnet, Benoît, Lipovac, Anne-Sophie, Loffeier, Vincent, Loison, Françoise, Lorchleac'h, Aurélien, Lorge, Fabienne, Loriferne, Jean-François, Lorléa'ch, Aurélien, Louart, Guillaume, Loury-Lariviere, Isabelle, Loustaud, Véronique, Lozniewski, Alain, Luciani, Roger-Charles, Luminitan Elena Lupean, Luca, Lureau, Pierre, Lutz-Murphy, Marie-France, Mbimba, Luwawu, M'Bey, Damien, Maakaroun, Abdallah, Macci, Valérie, Magdoud, Fatma, Mager, Guy, Magna, Théophile, Magny, Jean-François, Mahaza, Chetaou, Mahé, Isabelle, Maillard, Christine, Maillet, Jean-Jacques, Maillet, François, Maillez, Sébastien, Maillot, François, Maisonneuve, Antoine, Makdessi, Solène, Malbrunot, Claire, Malbruny, Brigitte, Malderet, Caroline, Malfuson, Jean-Valère, Malherbe, Philippe, Malherbe, Patrick, Malhiere, Sophie, Mandelbrot, Laurent, Mandin, Laurent, Mandjee, Aziza, Manéglier, Benjamin, Mansouria, Mohammed, Marcu, Elena, Mariette, Jean-Bernard, Mariette, Sylvie, Markarian, Jacques, Marmouset, Carole, Marpeau, Olivier, Marret, Olivier, Marsepoil, Thierry, Marterl-Lafay, Isabelle, Martha, Benoît, Marthelet, Patrick, Martin, Xavier, Martin, Florence, Martin, Pierre, Martin, Régine, Martin, Christian, Martin Lefèvre, Laurent, Martineau, Olivier, Martinet, Olivier, Martinez, Valérie, Martinot, Martin, Martres, Pascale, Marty, Sophie, Marty-Ane, Charles, Marzouk, Paul, Mascade, Géraldine, Masia, Florent, Masseron, Thierry, Masson, Loïc, Masson, Philippe, Matheron, Isabelle, Matica, Slavius, Matray, Olivier, Mattei, Marie-Françoise, Maubert, Bertrand, Maugein, Jeanne, Maureira, Juan-Pablo, May, Thierry, May, Adrien, Maze, Vincent, Meaudre Desgouttes, Eric, Mebazaa, Alexandre, Mechai, Frédéric, Medeau, Virginie, Megbemado, Richard, Mehri, Mona, Mein-Bottini, Myriam, Melis, Adrien, Mellier, Joelle, Ménager, Philippe, Ménard, Céline, Mendes-Martin, Lucile, Menguy, Anne-Claude, Menouar, Mohamed, Merabet, Taoufik, Mercury, Paul, Meregnani, Corinne, Mérigot, Philippe, Mermont, Sylvain, Merrouche, Yacine, Merville, Pierre-Gilles, Mesnage, Renaud, Mesnard, Louis, Messager, Aurélie, Messiaen, Thierry, Messika, Jonathan, Messner Pellenc, Patrick, Métenier, Hervé, Metton, Pierre, Meyer, Christian, Mialon, Michel, Miatello, Jordi, Michaud-herbst, Alban, Michault, Alain, Micheli, Sophie, Michon, Jocelyn, Baptiste Michot, Jean, Mielczarek, Severine, Mignart, Sophie, Mignaut, Virginie, Migraine Bouvagnet, Audrey, Mihout, Fabrice, Mille, Catherine, Millet, Olivier, Milpied, Noel, Mimoz, Olivier, Minet, Jacques, Minguet, Bertrand, Mohty, Mohamad, Moiton, Marie-Pierre, Monarchi, Richard, Monceau, Yannick, Monchi, Mehran, Monlun, Eric, Monsegu, Jacques, Montagne, Nathalie, Montcriol, Ambroise, Montmasson, Bernard, Mootien, Paramasiven, Moquet, Olivier, Morando, Virginie, Moreau, Anne-Sohie, Morel, Yves, Morelon, Emmanuel, Morin-Fatome, Armelle, Morincomme, Mathieu, Morlat, Philippe, Mosser, Laurent, Motard-Picheloup, Annie, Mottaz, Philippe, Moulinoux, Claire, Mouly, Laurence, Mourad, Georges, Mouries, Jean-Claude, Moussa, Hecham, Moustache, Audrey, Muir, Jean-François, Murbach, Valérie, N'guyen, Yohann, N'guyen, Jean-Claude, N'guyen-Khac, Florence, Nabholtz, Jean-Marc, Naceur, Tarik, Nakhleh, Jean, Nare, Aline, Nassif, Xavier, Nathan-Bonnet, Frédérique, Negrery, Huguette, Negrier, Claude, Neri, Dominique, Nesrine, Hakima, Neuwirth, Catherine, Ngami, Eugène, Carole Ngo Bell, Elisabeth, Nicobaharaye, Dieudonné, Nicolet, Laurent, Nicolet, Laurence, Nicolino, Marc, Niel, Philippe, Nikodijevic, Karine, Nkunzimana, Jean-Marie, Noel, Christian, Noirot, Alain, Noto, Philippe, Noulard, Marie-Noelle, Ntalu Nkato, Christophe, Nyunga, Martine, Obiols, Julien, Ochocki, Patrick, Odent, Sylvie, Olivier, Brigitte, Oliviero, Gérard, Ondze, Basile, Orléva, Oléna, Orode, Paul, Osman, Henri, Oswald, Eric, Otean, Paola, Ouazir, Abderkader, Ozanon, Christophe, Paccalin, Marc, Pages, Marie-Christine, Paindaveine, Bénédicte, Pangon, Béatrice, Pannecouck, Jean-Marie, Paquet, Jean-Christophe, Parent, Sabrina, Parisi-Duchene, Elisabeth, Pasche, Jérôme, Pasdeloup, Thierry, Patin, David, Patrigeon, René-Gilles, Patry, Isabelle, Paul, Jean-Gabriel, Pavel, Simona, Pavic, Michel, Pawlotsky, Jean-Michel, Payan, Christopher, Payen, Christiane, Péan, Yves, Péchinot, Frédérique, Péchinot, André, Pecquet, Matthieu, Pélaquier, Agnès, Peltier, Hervé, Penn, Pascale, Pennaforte, Jean-Loup, Perez, Didier, Périsson, Caroline, Perotin, Dominique, Perouse de Montclos, Michèle, Perreve, Sophie, Perronne, Christian, Perrotin, Dominique, Pesque, Valerie, Pestel-Caron, Martine, Pestre, Vincent, Petassou, Fabrice, Petit, Marie-Cécile, Petit Hoang, Camille, Petitjean, Philippe, Pettinelli, François, Peultier, Anne-Sophie, Piala, Jean-Marie, Pialoux, Gilles, Piau, Caroline, Picard, Aurélia, Picaud, Jean-Charles, Pichard, Eric, Pierre, Martin, Pierre, Fabrice, Pierrot, Paul, Piet, Emilie, Piffaut, Marie-Claude, Pigeon, Bertrand, Pignon, Carole, Pinon, Georges, Piquet, Jacques, Piriou, Vincent, Placidi, Eric, Plainfosse, Gillles, Plane, Christophe, Plantier, Isabelle, Claudiu-Plesa, Nicolai, Plésiat, Patrick, Plessis, Patrick, Plouzeau-Jayle, Chloé, Ploy, Marie-Cécile, Pochmalicki, Gilbert, Pofelski, Joanna, Poinsignon, Yves, Poirier, Anne-Sophie, Poitevin, Françoise, Pommier, Christian, Ponceau, Bénédicte, Poncelet, Christophe, Pop, Daniela, Porcheron, Martine, Pordes, Réginald, Porthault, Eric, Portneuf, Marc, Pottier, Anne, Pouedras, Pascal, Poulain, Jocelyne, Poulain, Gérard, Poupet, Hélène, Pouyanne, Julien, Pouzoullic, Marie, Poyart, Claire, Pozzetto, Bruno, Prazuck, Thierry, Pressac, Dominique, Prévost, Fabrice, Prince, Sylvie, Priollet, Pascal, Proost, Olivier, Protar, Daniel, Pujade Lauraine, Eric, Pujol, Antoine, Puybasset, Louis, Puyhardy, Jean, Quentin, Vincent, Quinsat, Denis, Rabier, Valérie, Radaoui, Fouzia, Radenac, Florian, Radenne, Sylvie, Raffenot, Didier, Raffi, François, Rahmani, Hassène, Ramanantsoa, Céline, Ranchon, Guillaume, Ranta, Dana, Raoult, Didier, Rasigade, Jean-Philippe, Rassiat, Emmanuel, Raulin, Olivia, Ravaud, Alain, Ravet, Nathalie, Razafimahefa, Hasinrina, Razafimahery, Mirana, Re, Daniel, Real, Philippe, Rebattu, Paul, Rebeyrotte, Catherine, Reboul, Pascal, Reboux, Anne-Hélène, Recule, Christine, Redonnet, Jean-Philippe, Redor, Alexis, Regouby, Yves, Rémy, Claude, Renard, Gisèle, Renard, Benoît, Renou, Frédéric, Repellin, Philippe, Reveil, Jean-Claude, Revel, Valérie, Reverseau, Anne, Revest, Mathieu, Rey, Philippe, Rey, Hyacine, Rey Zermati, Jany, Reyes Ortega, Guillermo, Reynaud, Alain, Reynes, Jacques, Rezgui, Nasseur, Riahi, Jacques, Ribes, David, Ribier, Arnaud, Richard, Christian, Richardin, Florence, Riche, Agnès, Richette, Pascal, Ridah, Khalid, Riegel, Philippe, Riehl, Frédéric, Rigaux, Françoise, Rioux, Christophe, Rival, Gilles, Rivière, Brigitte, Robert, Henri, Robert, René, Robillard, Pierre-Yves, Roblin, Mélanie, Roblot, Pascal, Roblot, France, Rogeaux, Olivier, Roger, Pierre-Marie, Rohmer-Heitz, Dominique, Rolland, Christophe, Roncato-Saberane, Mariam, Ronda, Isabelle, Rondepierre, Philippe, Roque-Afonso, Anne-Marie, Rosay, David, Rose, Christian, Roseau, Jean-Baptiste, Rosello, Sophie, Rosselli, Sylvène, Rossignol, Serge, Rostaing, Lionel, Roth, Christian, Rothe, Marie-Rose, Roubert, Xavier, Rouget, Sébastien, Rouidi, Ahmed, Roulier, Philippe, Rouquet, Yannick, Rouquette-Vincent, Isabelle, Roure Sobas, Chantal, Rousseau, Sylvaine, Rousseau, Florence, Roussel, Etienne, Roussel, Jean-Christian, Roussel, Christophe, Roussellier, Patricia, Roy, Christophe, Royer, Daniel, Roze, Jean-Christophe, Rozec, Bertrand, Ruimy, Raymond, Ruppé, Etienne, Ruyer, Olivier, Sabbat, Sébastien, Saghi, Tahar, Saigne, Christophe, Sakek, Necera, Salama, Gilles, Salanoubat, Celia, Salaun-Beretta, Guenaelle, Saliba, Elie, Salles, Gilles, Salmon, Odile, Louis Salomon, Jean, Salord, Jean-Michel, Salvucci, Marina, Samson, Thierry, Sanchez, Richard, Sansot, Dominique, Saplacan, Mihaela, Saroufim, Carlo, Sauder, Philippe, Sautereau, Denis, Savare, Ferdinand, Savatier, Rim, Scemla, Anne, Schendel, Adeline, Schmitt, Anna, Schmitt, François, Schmitt, Alain, Schneerson, Morgane, Schneider, Francis, Schved, Jean-François, Schwebel, Carole, Sebban, Anthony, Secher, Aline, Sédillot, Nicholas, Sedjelmaci, Yacine, Segonds, Christine, Seignovert, Camille, Seknazi, Corinne, Semenescu, Marius, Sément, Arnaud, Semet, Jean-Claude, Semet, Guy, Sennevile, Eric, Serier, Miloud, Serre, Arnaud, Seta, Nathalie, Seyrig, Jacques-Arnaud, Sgro, Eric, Sibony-Prat, Joyce, Sicsic, Jean-Luc, Sifaoui, Farid, Signouret, Thomas, Sigur, Nicolas, Silhadi, Souad, Siméoni, Umberto, Simian, Bernard, Similowski, Thomas, Simon, Georges, Simon, François, Simonin, Catherine, Sirbu, Cristina, Sire, Jean-Marie, Sivadon-Tardy, Valérie, Sivery, Bruno, Slama, Michel, Smati, Salim, Sobesky, Rodolphe, Sokeng-Affoule, Hélène, Sollet, Jean-Pierre, Sommabère, André, Sondag, Daniel, Soraudeau, Florence, Sotto, Albert, Soulie, Bruno, Souply, Laurent, Souquet, Jean-Christophe, Soury, Pierre, Souweine, Bertrand, Stahl, Jean-Paul, Steibach, Marie-Isabelle, Stephan, Robin, Stoclin, Annabelle, Stolidi, Philippe, Strock, Paul, Suatean, Diana, Subra, Jean-François, Sucin, Yves, Suel, Philippe, Sullice, Marc, Szwebel, Tali-Anne, Tacchini, Laurent, Talabani-Boizot, Hana, Talarmin, Jean-Philippe, Taleb, Fethi, Tamalet, Catherine, Tamion, Fabienne, Tandonnet, Olivier, Tankovic, Jacques, Tardy, Véronique, Tassot, Christelle, Taurin, Gregory, Taylor, Sabine, Tchenio, Xavier, Tebib, Jacques, Teillet, Laurent, Teixeira, Antonio, Terki, Mustapha, Tesseydre, Sonia, Texier, Jean-Claude, Texier, Anthony, Thellier, Jean-Paul, Thibaud, Didier, Thibault, Michel, Thibaut, Freddy, Thierry, Jacques, Thoinet, Sylvie, Thomas, Pierre, Thomas, René, Thomas, Yves, Thomas, Caroline, Thore, Jean, Thouret, Jean-Marc, Thouvenin, Maxime, Thuet, Francis, Tigaizin, Ahmed, Tigaud, Sylvestre, Tiry, Catherine, Tissieres, Pierre, Tissot, Alain, Tixier, Anne, Touati, Kamel, Toubia, Marie-Lina, Toullalan, Olivier, Tourani, Jean-Marc, Tourrand, Bernadette, Touze, Yvan, Trabelsi-Jnifen, Asma, Traissac, Laurent, Anh Tran, Tu, Tran, Vanessa, Tricoire, Joelle, Tronchon, Laurent, Trouiller, Sébastien, Trystram, David, Ahmed, Becaid, Tsouria, Tuca, Mirela, Turpin, Mathilde, Vache, Bernard, Vachée, Anne, Vaillant, Christine, Valadier, Patrick, Valayer, Patrick, Valette, Xavier, Vallet, Françis, Van de Velde, Florence, Vanden Einjden, Serge, Vandenesch, François, Vande-perre, Philippe, Varin, Marie-Christine, Vary, Gwenaelle, Vaschalde, Yvan, Vassallo, Matteo, Vasse, Marc, Vasseur, Manica, Vatan, Rémi, Vaucel, Jacques, Vergnaud, Michel, Verhaeghe, Annick, Vermesch-Langlin, Annie, Vernet, Guy, Vernet Garnier, Véronique, Verrier, Virginie, Vessieres, Annie, Vialette, Véronique, Viard, Jean-Paul, Vieillard Baron, Antoine, Vighetto, Alain, Villemain, Marc, Villers, Daniel, Vilque, Jean-Pierre, Vinay, Agnès, Vincent, Didier, Vincent, Pascal, Vincent, Colette, Vincent, Simon, Vinci, Clara, Viole, Didier, Violette, Jérémie, Viquesnel, Gerard, Virlouvet, Anne-Laure, Visentin, Séverine, Vittecoq, Daniel, Vodovar, Dominique, Vrigneaud, Laurence, Vu-Thien, Hoang, Vuotto, Fanny, Wafo, Estelle, Wagner, Michel, Walid, Nicola, Walter, Elisabeth, Watson, Sarah, Weinbreck, Pierre, Weinbronn, Eva, Weiss, Emmanuel, Weitten, Thierry, Welker, Yves, Westeel, Pierre-François, Wink, Olivier, Wintenberger, Claire, Woerther, Paul-Louis, Worcel, Isabelle, Wuillai, Anne, Wurmser, Marc, Xavier, Jacob, Yazdanpanah, Yazdan, Yehia, Aihem, Yvenou, Sterenn, Zagdoun, Elie, Zagozda, Dominique, Zame, Thierry-Pascal, Zamfiri, Oana, Zanaldi, Hélène, Zandecki, Marc, Zaoui, Eric, Zarrouk, Virginie, Zarski, Jean-Pierre, Zavadil, Patrick, Zeller, Valérie, Zerbib, Franck, Zerr, Vincent, Zgarni, Lémia, Zoulim, Fabien, Zoveda, Patrick, Zuber, Pierre, Zumbo, Christian, Charlier, Caroline, Perrodeau, Élodie, Leclercq, Alexandre, Cazenave, Benoît, Pilmis, Benoît, Henry, Benoît, Lopes, Amanda, Maury, Mylène M, Moura, Alexandra, Goffinet, François, Dieye, Hélène Bracq, Thouvenot, Pierre, Ungeheuer, Marie-Noëlle, Tourdjman, Mathieu, Goulet, Véronique, de Valk, Henriette, Lortholary, Olivier, Ravaud, Philippe, and Lecuit, Marc
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- 2017
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7. Empagliflozin improved systolic blood pressure, endothelial dysfunction and heart remodeling in the metabolic syndrome ZSF1 rat
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Park, Sin-Hee, Farooq, Muhammad Akmal, Gaertner, Sébastien, Bruckert, Christophe, Qureshi, Abdul Wahid, Lee, Hyun-Ho, Benrahla, Djamel, Pollet, Brigitte, Stephan, Dominique, Ohlmann, Patrick, Lessinger, Jean-Marc, Mayoux, Eric, Auger, Cyril, Morel, Olivier, and Schini-Kerth, Valérie B.
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- 2020
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8. Rifampicin reverses nicardipine effect inducing uncontrolled essential hypertension
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Cordeanu, Elena‐Mihaela, Gaertner, Sébastien, Faller, Alix, Mirea, Corina, Lessinger, Jean‐Marc, Kemmel, Veronique, and Stephan, Dominique
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- 2017
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9. Mitomycin C Pharmacokinetics as Predictor of Severe Neutropenia in Hyperthermic Intraperitoneal Therapy
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Kemmel, Véronique, Mercoli, Henri-Alexis, Meyer, Nicolas, Brumaru, Daniel, Romain, Benoit, Lessinger, Jean-Marc, and Brigand, Cécile
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- 2015
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10. Co-administration of mTor Inhibitors and Carbamazepine May Lead to Ineffectiveness of Therapy: A Case Report of a 24-year-old Man
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Sawan, Asma, primary, Becker, Guillaume, additional, Lefevre, Paul, additional, Brumaru, Daniel, additional, Bergerat, Jean-pierre, additional, Lessinger, Jean-marc, additional, and Kemmel, Véronique, additional
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- 2022
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11. Development of a Specific Assay for Pancreatic Lipase Activity for Diagnostic Purposes
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Férard, Georges, Lessinger, Jean Marc, Arzoglou, Panteleimon, Visvikis, Atanase, Junge, Wolfgang, Mackness, M. I., editor, and Clerc, M., editor
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- 1994
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12. Effects of oxidation on the hydrolysis by cholesterol esterase of sitosteryl esters as compared to a cholesteryl ester
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Julien-David, Diane, Ennahar, Saïd, Miesch, Michel, Geoffroy, Philippe, Raul, Francis, Aoude-Werner, Dalal, Lessinger, Jean-Marc, and Marchioni, Eric
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- 2009
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13. Myocardial injury in coronavirus disease 19 (Covid-19): main pathophysiological mechanisms and clinical utility of cardiac biomarkers
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Kamel, Saïd, Raynor, Alexandre, Zozor, Samuel, Lacape, Geneviève, Brunel, Valéry, Nivet-Antoine, Valérie, Collin-Chavagnac, Delphine, Peoc’h, Katell, Cohen, Ariel, Lassoued, Amin Ben, Chévrier, Marc, Alemann, Mathieu, Lessinger, Jean-Marc, Bérard, Annie, Sapin, Vincent, Beauvieux, Marie-Christine, Levy, Pacifique, Lehmann, Sylvain, Mécanismes physiopathologiques et conséquences des calcifications vasculaires - UR UPJV 7517 (MP3CV), Université de Picardie Jules Verne (UPJV)-CHU Amiens-Picardie, AP-HP - Hôpital Bichat - Claude Bernard [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), CHU Bordeaux [Bordeaux], CHU Rouen, Normandie Université (NU), Innovations thérapeutiques en hémostase = Innovative Therapies in Haemostasis (IThEM - U1140), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), CHU Necker - Enfants Malades [AP-HP], Centre Hospitalier Lyon Sud [CHU - HCL] (CHLS), Hospices Civils de Lyon (HCL), CHU Saint-Antoine [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), CHU Tenon [AP-HP], Thrombose, atherothrombose et pharmacologie appliquée, Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM), Hôpital de la Timone [CHU - APHM] (TIMONE), Les Hôpitaux Universitaires de Strasbourg (HUS), CHU Clermont-Ferrand, Génétique, Reproduction et Développement (GReD), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne (UCA), Centre de résonance magnétique des systèmes biologiques (CRMSB), Université de Bordeaux (UB)-Centre National de la Recherche Scientifique (CNRS), Cellules Souches, Plasticité Cellulaire, Médecine Régénératrice et Immunothérapies (IRMB), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), and Pour le Groupe de Travail de la SFBC « Marqueurs Biochimiques de la pathologie Covid-19 »: Isabelle Aimone-Gastin, Stéphanie Alcaraz, Stéphane Allouche, Malika Balduyck, Françoise Barbé, Yann Barguil, Jean-Philippe Bastard, Jean-Louis Beaudeux, Marie-Christine Beauvieux, Amin Ben Lassoued, Isabelle Benz de Bretagne, Annie Bérard, Laurent Bermont, Edith Bigot-Corbel, Muriel Bost, Valery Bourbonneux, Valery Brunel, Jean-Luc Carré, Camille Chenevier-Gobeaux, Marc Chevrier, Giulia Chinetti, Delphine Collin-Chavagnac, Hervé Delacour, Delphine Delevallée, François Desroys du Roure, Patrice Faure, Jean-Philippe Galhaud, Anne Galinier, Thierry Hauet, Carine Helj, Emilie Jolly, Said Kamel, Sylvain Lehmann, Aline Leroy, Jean-Marc Lessenger, Pacifique Levy, Anne-Marie Lorec-Penet, Samir Mesli, Dagui Monnet, Caroline Moreau, Laurence Mouly, Valérie Nivet-Antoine, Nathalie Oueidat, Mathieu Pecquet, Katell Peoc’h, Laurence Piéroni, Carole Poupon, Martine Roubille, Benoit Rucheton, Medhi Sakka, Vincent Sapin, Vincent Saunier, Florian Scherrer, François Schmitt, Sabine Zaepfel, Samuel Zozor
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myocardite ,peptides natriurétiques ,SARS-CoV-2 ,myocarde ,[SDV]Life Sciences [q-bio] ,troponine ,Covid-19 - Abstract
International audience; Pour citer cet article : Atteintes myocardiques au cours de la maladie à coronavirus 19 (Covid-19) : principaux mécanismes physiopathologiques et utilité clinique des biomarqueurs cardiaques.
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- 2021
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14. High severe acute respiratory coronavirus virus 2 (SARS-CoV-2) seroconversion rate among geriatric staff from Strasbourg University Hospitals
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Panaget, Baptiste, primary, Velay, Aurélie, additional, Gontard, Louise, additional, Severac, François, additional, Meyer, Maxence, additional, Antoni, Elisabeth, additional, Kaltenbach, Georges, additional, Kling-Pillitteri, Laurence, additional, Sammour, Yasmine, additional, Hansmann, Yves, additional, Hernandez, Céline, additional, Lavigne, Thierry, additional, Lessinger, Jean-Marc, additional, Gonzalez, Maria, additional, Wendling, Marie-Josée, additional, Gallais, Floriane, additional, Kepka, Sabrina Garnier, additional, and Fafi-Kremer, Samira, additional
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- 2021
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15. Influenza vaccination and prognosis of COVID ‐19 in hospitalized patients with diabetes: Results from the CORONADO study
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Diallo, A, Pichelin, Matthieu, Wargny, Matthieu, Gourdy, Pierre, Bonnet, JB, Hadjadj, Samy, Cariou, Bertrand, Sultan, Ariane, Galtier, Florence, Mahot, Pascale, Fournier‐Guilloux, Anne‐Laure, Mauduit, Nicolas, Bigot‐corbel, Edith, Boureau, Anne‐Sophie, Dekcer, Laure, Ernould, Audrey, Primot, Claire, Seguin, Anne, Joliveau, Marielle, Pouvreau, Sonia, FOURNIER, Chloé, Thureau, Jeremy, Fonteneau, Edith, Hublain, Pamela, Nantes, Chu, Agasse, Carole, Kergaradec, Mathilde DE, Minville, Vincent, Vardon‐Bounes, Fanny, Martin‐Blondel, Guillaume, Tramunt, Blandine, Turnin, Marie‐Christine, Hanaire, Hélène, Mansuy, Jean‐Michel, Fabre, Didier, Arhainx, Marie‐Blanche, Cazals, Laurent, Combes, Laure, Lami, Emmanuelle, Cianferani, Mallory, Megarbane, Bruno, Leroy, Pierre, Gautier, Jean‐François, Vidal‐Trecan, Tiphaine, Riveline, Jean‐Pierre, Laplanche, Jean‐Louis, Mouly, Stéphane, Potier, Louis, Roussel, Ronan, Taher, Malak, Abouleka, Yawa, Yaker, Fetta, Carlier, Aurelie, Boutten, Anne, Hallot‐Feron, Marilyne, Mourah, Fadila, Thivolet, Charles, Blond, Emilie, Rolland, Muriel, Mendez, Josep Verdecho, Alexandre, Marine, Pottecher, Julien, Richer, Emilie, Meyer, Laurent, Luca, Florina, Lessinger, Jean‐Marc, Bahougne, Thibault, Guerci, Bruno, Ludwig, Lisa, Benzirar, Siham, Malaplate, Catherine, Matton, Thierry, Poissy, Julien, Faure, Karine, Fontaine, Pierre, Baudoux, Florence, Vambergue, Anne, Pekar, Jean David, Lambert, Marc, Yelnik, Cécile, Bruandet, Amélie, Petit, Laurent, Neau, Didier, Rigalleau, Vincent, Berard, Annie, Galioot, Amandine, Coudroy, Remy, Thille, Arnaud, Robert, René, Roblot‐Cazenave, France, Rammaert, Blandine, Saulnier, Pierre Jean, Piguel, Xavier, Benhenda, Nesrine, Husson, Camille, Olivier, Celine, Torremocha, Florence, Fraty, Mathilde, d'assigny, Marie Flamen, Miot, Aurelie, Bossard, Valentin, Klouche, Kada, Makinson, Alain, Bonnet, Jean‐Baptiste, Foulongne, Vincent, Aubron, Cécile, Ansart, Séverine, Kerlan, Véronique, Quiniou, Pascale, Carre, Jean‐Luc, Quesnot, Stéphane, Laviolle, Bruno, Schwebel, Carole, Epaulard, Olivier, Benhamou, Pierre‐Yves, Betry, Cécile, Borel, Anne‐Laure, Lablanche, Sandrine, Guergour, Dorra, Duclos, Catherine, Cosson, Emmanuel, Guyot, Erwan, Deniau, Aurore, Nguyen, Phucthutrang, Reznik, Yves, Joubert, Michael, Allouche, Stéphane, Guittet, Lydia, Grange, Steven, Etienne, Manuel, Prévost, Gaëtan, Brunel, Valéry, Lagier, Jean‐Christophe, Raoult, Didier, Dutour, Anne, Gaborit, Bénédicte, Boulllu, Sandrine, Darmon, Patrice, Lasbleiz, Adèle, Cerino, Mathieu, Romain, Fanny, Houssays, Marie, Quenot, Jean Pierre, Piroth, Lionel, Vergès, Bruno, Duvillard, Laurence, Bonnotte, Bernard, Mercat, Alain, Dubee, Vincent, Allix, Ingrid, Rodien, Patrice, Dhersin, Robin, Lebeault, Maylis, Trzepizur, Wojciech, Loison, Jocelyne, Brangier, Antoine, Asfar, Pierre, Reynier, Pascal, Larcher, Françoise, Joubaud, Françoise, Andreu, Marie‐Rita, Urbanski, Geoffrey, Hubert, Laurent, Annweiler, Cedric, Dellamonica, Jean, Courjon, Johan, Chevalier, Nicolas, Chinetti, Giulia, Chafai, Magda, Mourvillier, Bruno, Bani‐Sadr, Firouze, Barraud, Sarra, Delemer, Brigitte, Gillery, Philippe, Labedade, Pascale, Chabrol, Amélie, Penfornis, Alfred, Petit, Catherine, Amadou, Coralie, Adler, Maxime, Dubost, Clément, Conan, Pierre‐Louis, Bordier, Lyse, Ceppa, Franck, Garcia, Cyril, Sollier, Mathilde, Dupuy, Olivier, Laplance, Sophie, Billuart, Olivier, Aroulanda, Marie Joseph, Olivier, Frédérique, Ayon, Florence, Wilhelm, Nathalie, Epelboin, Loic, Sabbah, Nadia, Charpin, Aurelie, Squara, Pierre, Belliard, Olivier, Dubois, Claude, Marre, Michel, Auchabie, Johann, Courtois, Roxane, Duriez, Thierry, Mergey, Tiphaine, Vallee, Laura, Seguin, Laetitia, Al‐Salameh, Abdallah, Lanoix, Jean‐Philippe, Soriot‐Thomas, Sandrine, Bourgeois‐Descouls, Anne‐Marie, Desailloud, Rachel, Germain, Natacha, Galusca, Bogdan, Belleton, Gwenaelle, Marouani, Nesrine, Palaghiu, Delia, Hammour, Amira, Berdaguer, Fernando, Klopfenstein, Thimothée, Zayet, Hajer, Winiszewski, Patrice, Zanusso, Marie, Garnier, Pauline, Julier, Ingrid, Hamzaoui, Karim, Marty‐Gres, Sophie, Sadki, Tarik, Cadot, Lucile, Dubost, Jean‐Louis, Gonfroy, Céline, Campinos, Catherine, Martres, Pascale, Coulhon, Marie Pierre, Allou, Nicolas, Bachir, Marwa, Hoang, Stella, Kembellec, Candice, Suply, Olivia, Kharcha, Fatima, Devouge, Anne‐Claire, Flaus‐Furmanuk, Anna, Madeline, Isabelle, Ehinger, Vincent, Bastard, Sophie, Raffray, Loic, Renou, Frederic, Bojarski, Aude, Paul, Caroline, Borsu, Karine, Gorlin, Angelique, Bernardo, Servane, Ut, Carole Truong, Renaud, Stephane, Vignoles, Antoine, Foch, Emilie, Masse, Laurie, Grand, Hubert, Ferrand, Helene, Raffaitin‐Cardin, Christelle, Zellagui, Hadjer, Castang‐Brachet, Celine, Boury, Frederique, Tena, Ana Alvarez, Moura, Isabelle, Kalfon, Pierre, Darasteanu, Juliana, Monier, Arnaud, Foucault, Pascal, Depuille, Alexandra, Laugier‐Robiolle, Stéphanie, Caneiro, Patrick, Basso, Maud, Larger, Etienne, Bouam, Samir, Benzenati, Wahiba, Bachir, Leila Ait, Pillegand, Camille Cussac, Vasse, Marc, Michard, Christophe, Montanier, Nathanaëlle, Millot, Luc, Crepet, Françoise, Ratsimba, Danielle, Bouiller, Kevin, Borot, Sophie, Bruckert, Isabelle, Clergeot, Annie, Schillo, Franck, Vignes, Dorothée, Bourgeon‐Ghittori, Muriel, Lachgar, Hamoud, Cursay, Claire Lambert DE, Levante, Stéphane, Auregan, Jean Charles, Merlet, Antoine, Zaragoza, Cécile, Arnault, Gwénaëlle, Loupp, Anne‐Gaëlle, Lesieur, Olivier, Roncato‐Saberan, Mariam, Gouet, Didier, Lemarie, Romain, Allano, Hong_an, Vivier, Emmanuel, Pariset, Caroline, Luyton, Cédric, Marchand, Lucien, Doroszewski, Fanny, Pecquet, Matthieu, Perard, Laurent, Vuillermoz‐Blas, Sylvie, Kacki, Nicolas, Charrier, Patricia, Ducet‐Boiffard, Amélie, Roure, Françoise Desroys, Bourron, Olivier, Bonnefont‐Rousselot, Dominique, Laroche, Suzanne, Phan, Franck, Hartemann, Agnès, CAUSSY, Cyrielle, Disse, Emmanuel, Guerin, Claude, Perpoint, Thomas, Moulin, Philippe, CARTIER, RÉGINE, Hariri, Geoffroy, Chopin, Dorothée, Vatier, Camille, Bourcigaux, Nathalie, Chaigneau, Emmanuelle, Christin‐Maitre, Sophie, Donadille, Bruno, Feve, Bruno, Lamothe, Sophie, Sarfati, Julie, Pernet, Pascal, Chambon, Anne, Demarsy, Delphine, Campagne, Hugo, Latil‐Plat, Françoise, Berne, Monica, Grinand, Marilyne, Touzet, Marion, Zabulon, Aydrey, Craspag, Jocelyne, Ledoux, Catherine, Contaret, Cedric, Janand‐Delenne, Blandine, Giraud, Anaïs, Lacrimini, Marie Lou, Arrivie, Joëlle, Ancelle, Deborah, Guillois, Carine, Fremy, Bénédicte, Chaalal, Amina, Barrande, Gaëlle, Dorange, Anne, Rouanet, Eglantine, Seret‐Begue, Dominique, Saoud, Audrey, Guedj, Anne‐Marie, Bedos, Nathalie, Velayoudom, Fritz‐Line, Dumas, Marie, Gonda, Benoite, Coffin, Christine, Gibiat, Stéphanie, Lungo, Myriam, Bully, Chantal, Serusclat, Pierre, Bully, Stella, Carre, Patricia, Leberre, Jean‐Philippe, Elkhoury, Carlos, THIEUX, Marine, Paradisi‐Prieur, Laetitia, Physiologie & médecine expérimentale du Cœur et des Muscles [U 1046] (PhyMedExp), Université de Montpellier (UM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), and Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)
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2019-20 coronavirus outbreak ,medicine.medical_specialty ,Coronavirus disease 2019 (COVID-19) ,Hospitalized patients ,Influenza vaccine ,Endocrinology, Diabetes and Metabolism ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,[SDV]Life Sciences [q-bio] ,03 medical and health sciences ,0302 clinical medicine ,Endocrinology ,Internal medicine ,Diabetes mellitus ,Influenza, Human ,Internal Medicine ,Diabetes Mellitus ,Research Letter ,Medicine ,Humans ,030212 general & internal medicine ,ComputingMilieux_MISCELLANEOUS ,030304 developmental biology ,0303 health sciences ,business.industry ,SARS-CoV-2 ,Vaccination ,COVID-19 ,medicine.disease ,Prognosis ,Research Letters ,3. Good health ,Hospitalization ,Propensity score matching ,business - Abstract
International audience
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- 2021
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16. Anti-SARS-CoV-2 Antibodies Persist for up to 13 Months and Reduce Risk of Reinfection
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Gallais, Floriane, primary, Gantner, Pierre, additional, Bruel, Timothée, additional, Velay, Aurelie, additional, Planas, Delphine, additional, Wendling, Marie-Josée, additional, Bayer, Sophie, additional, Solis, Morgane, additional, Laugel, Elodie, additional, Reix, Nathalie, additional, Schneider, Anne, additional, Glady, Ludovic, additional, Panaget, Baptiste, additional, Collongues, Nicolas, additional, Partisani, Marialuisa, additional, Lessinger, Jean-Marc, additional, Fontanet, Arnaud, additional, Rey, David, additional, Hansmann, Yves, additional, Kling-Pillitteri, Laurence, additional, Schwartz, Olivier, additional, De Sèze, Jérome, additional, Meyer, Nicolas, additional, Gonzalez, Maria, additional, Schmidt-Mutter, Catherine, additional, and Fafi-Kremer, Samira, additional
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- 2021
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17. Sirolimus Pharmacokinetics Variability Points to the Relevance of Therapeutic Drug Monitoring in Pediatric Oncology
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Sabo, Amelia-Naomi, primary, Jannier, Sarah, additional, Becker, Guillaume, additional, Lessinger, Jean-Marc, additional, Entz-Werlé, Natacha, additional, and Kemmel, Véronique, additional
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- 2021
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18. Extracellular haemoglobin, oxidative stress and quality of red blood cells relative to perioperative blood salvage
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Gueye, Papa Madieye, Bertrand, Françoise, Duportail, Guy, and Lessinger, Jean-Marc
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- 2013
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19. IFCC reference procedures for measurement of the catalytic concentrations of enzymes: corrigendum, notes and useful advice: International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) - IFCC Scientific Division
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Schumann, Gerhard, Canalias, Francesca, Joergensen, Poul J., Kang, Dongchon, Lessinger, Jean-Marc, and Klauke, Rainer
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- 2013
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20. Analysis of the RNA chaperoning activity of the hepatitis C virus core protein on the conserved 3′X region of the viral genome
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Sharma, Kamal Kant, de Rocquigny, Hugues, Darlix, Jean Luc, Lavergne, Jean-Pierre, Pénin, François, Lessinger, Jean-Marc, and Mély, Yves
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- 2012
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21. IFCC primary reference procedures for the measurement of catalytic activity concentrations of enzymes at 37°C. Part 9: Reference procedure for the measurement of catalytic concentration of alkaline phosphatase: International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) Scientific Division, Committee on Reference Systems of Enzymes (C-RSE)1)
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Schumann, Gerhard, Klauke, Rainer, Canalias, Francesca, Bossert-Reuther, Steffen, Franck, Paul F.H., Gella, F.-Javier, Jørgensen, Poul J., Kang, Dongchon, Lessinger, Jean-Marc, Panteghini, Mauro, and Ceriotti, Ferruccio
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- 2011
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22. Traceability of values for catalytic activity concentration of enzymes: a Certified Reference Material for aspartate transaminase
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Toussaint, Brigitte, Emons, Hendrik, Schimmel, Heinz G., Bossert-Reuther, Steffen, Canalias, Francesca, Ceriotti, Ferruccio, Férard, Georges, Ferrero, Carlo A., Franck, Paul F.H., Gella, Javier F., Henny, Joseph, Jørgensen, Poul J., Klauke, Rainer, Lessinger, Jean-Marc, Mazziotta, Daniel, Panteghini, Mauro, Ueda, Shigeru, and Schumann, Gerhard
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- 2010
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23. Kinetic analysis of the nucleic acid chaperone activity of the Hepatitis C virus core protein
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Sharma, Kamal kant, Didier, Pascal, Darlix, Jean Luc, de Rocquigny, Hugues, Bensikaddour, Hayet, Lavergne, Jean-Pierre, Pénin, François, Lessinger, Jean-Marc, and Mély, Yves
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- 2010
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24. Extracellular haemoglobin, oxidative stress and quality of red blood cells relative to perioperative blood salvage
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Gueye, Papa Madieye, Bertrand, Françoise, Duportail, Guy, and Lessinger, Jean-Marc
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- 2010
25. IFCC reference procedures for measurement of the catalytic concentrations of enzymes: corrigendum, notes and useful advice: International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) - IFCC Scientific Division
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Schumann, Gerhard, Canahas, Francesca, Joergensen, Poul J., Kang, Dongchon, Lessinger, Jean-Marc, and Klauke, Rainer
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- 2010
26. Added value of serial bio-adrenomedullin measurement in addition to lactate for the prognosis of septic patients admitted to ICU
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Blet, Alice, De Roquetaillade, Charles, Hartmann, Oliver, Struck, Joachim, Mebazaa, Alexandre, Chousterman, Benjamin Glenn, Laterre, Pierre François, Berghe, Caroline, Dujardin, Marie France, Renard, Suzanne, Wittebole, Xavier, Collienne, Christine, Zapatero, Diego Castanares, Dugernier, Thierry, Vinetti, Marco, De Schryver, Nicolas, Thirifays, Anne, Mairesse, Jacques, Huberlant, Vincent, Petre, Hélène, Buelens, Isabelle, Henin, Pierre, Trine, Hugues, Laurent, Yves, Sébastien, Loix, Geukens, Paul, Kehl, Laurent, François, Bruno, Vignon, Philippe, Pichon, Nicolas, Begot, Emmanuelle, Fedou, Anne Laure, Chapellas, Catherine, Galy, Antoine, Rodier, Nicolas, Baudrillart, Ludmilla, Nouaille, Michelle, Laleu, Séverine, Mancia, Claire, Daix, Thomas, Bourzeix, Paul, Herafa, Isabelle, Duchambon, Anne Aurore, Lascarrou, Jean Baptiste, Fiancette, Maud, Colin, Gwenhael, Henry-Lagarrigue, Matthieu, Lacherade, Jean Claude, Lebert, Christine, Martin-Levfèvre, Laurent, Vinatier, Isabelle, Yehia, Aihem, Bachoumas, Konstantinos, Joret, Aurélie, Reignier, Jean, Rousseau, Cécille, Maquigneau, Natacha, Alcourt, Yolaine, Zinzonni, Vanessa Erragne, Deschamps, Angélique, Robert, Angelina, Mercier, Emmanuelle, Simeon-Vieules, Véronique, Aubrey, Aurélie, Mabilat, Christine, Garot, Denis, Ehrmann, Stephan, Legras, Annick, Jouan, Youenn, Dequin, Pierre François, Guillon, Antoine, Bodet-Contentin, Laetitia, Rouve, Emmannuelle, Salmon, Charlotte, Brick, Lysiane, Massat, Stéphanie, Desachy, Arnaud, Fally, Marie Anne, Robin, Laurence, Cracco, Christophe, Lafon, Charles, Calvat, Sylvie, Rouleau, Stéphane, Schnell, David, Lasocki, Sigismond, Fesard, Philippe, Leblanc, Damien, Bouhours, Guillaume, Chassier, Claire, Conte, Mathieu, Gaillard, Thomas, Denou, Floriane, Kerymel, Mathieu, Guyon, Marion, Loiez, Anthéa, Lebreton, Stéphanie, Meziani, Ferhat, Allam, Hayat, Chenaf, Samir, Rahmani, Hassène, Heenen, Sarah, Kummerlen, Christine, Delabranche, Xavier, Boivin, Alexandra, Clere-Jehl, Raphaël, Rabouël, Yannick, Pottecher, Julien, Bayer, Sophie, Metzger, Catherine, Hecketsweiler, Stéphane, Ludes, Pierre Olivier, Besancenot, Hortense, Dhif, Nadia, Freys, Guy, Lessinger, Jean Marc, Launoy, Anne, Ruimy, Aude, Meyer, Alain, Szozot, M., Deye, Nicolas, Gayat, Etienne, Fournier, Marie Céline, Abroug, Sarra, Louadah, Badr, Feliot, Elodie, Voicu, Sebastian, Malissin, Isabelle, Megarbane, Bruno, Manivet, Philippe, Victori, Gardianot, Kelly, Da Silva, La Foucher, Béatrice, Pierre, Valérie, Kerdjana, Lamia, Beeken, Thomas, Goury, Antoine, Garcon, Pierre, Gaugain, Samuel, Huot, Benjamin, Barthelemy, Romain, Soyer, Benjamin, Jacob, Laurent, Legrand, Matthieu, Fourniar, Marie Céline, Bonnet, Francine, Legall, Chloé, Oueslati, Haikel, Cupaciu, Alexandru, Manivat, Philippe, Louadeh, Badr, Sonneville, Romain, Letrou, Sophie, Bouadma, Lila, Mourvillier, Bruno, Deiler, Véronique, Magalhaes, Eric, Neuville, Mathilde, Timsit, Jean François, Radjou, Aguila, Gaudry, Stéphane, Dubief, Emeline, Messika, Jonathan, La Combe, Béatrice, Roux, Damien, Berquier, Guillaume, Laissi, Mohamed, Ricard, Jean Damien, Constantin, Jean Michel, Perbet, Sebastien, Delmas, Julie, Pascal, Julien, Cayot, Sophie, Guerin, Renaud, Jabaudon, Matthieu, Roszyk, Laurence, Rolhion, Christine, Bourdier, Justine, Lematte, Mathilde, Gouhier, Charlène, Verlhac, Camille, Godet, Thomas, Radji, Sophiano, Caumon, Elodie, Thibault, Sandrine, Marx, Nikolaus, Schuerholz, Tobias, Pezechk, Jessica, Feld, Florian, Brülls, Christian, Beeker, Thorben, Simon, Tim Philipp, Deisz, Robert, Schindler, Achim, Meier, Bianca, Janisch, Thorsten, Hohn, Andreas, Schedler, Dirk, Wetsch, Wolfgang, Schröder, Daniel, Meier-Hellmann, Andreas, Lucht, Alexander, Henker, Robert, Römmer, Magdalena, Meinig, Torsten, Zacharowski, Kai D., Meybohm, Patrick, Lindau, Simone, Mutlak, Haitham, Kluge, Stefan, Ringeis, Grit, Füllekrug, Birgit, Singer, Brigitte, Nierhaus, Axel, Bangert, Katrin, De Heer, Geraldine, Frings, Daniel, Fuhrmann, Valentin, Müller, Jakob, Schreiber, Jörg, Sensen, Barbara, Siedler, Stephanie, Siewecke, Annekatrin, Söffker, Gerold, Wichmann, Dominic, Kerinn, Mélanie, Jaschinski, Ulrich, Kreuser, Ilse, Zanquila, Marlene, Kortgen, Andreas, Bloos, Frank, Gonnert, Falk, Thomas-Rüddel, Daniel, Haucke, Anja, Kolanos, Steffi, Kohlberg, Karina Knuhr, Bloos, Petra, Schwope, Katrin, Di Somma, Salvatore, Rossella, Marino, Russo, Veronica, Simona, Santarelli, Bartoli, Christopher, Navarin, Sylvia, Bongiovanni, Cristina, Orru, Michela, Quatrocchi, Daniela, Zoccoli, Giada, Varchetta, Antonella, Antonelli, Massimo, De Pascale, Gennaro, Vallecoccia, Maria Sole, Cutuli, Salvatore Lucio, Digravio, Valentina, Quattrochi, Daniela, D'Arrigo, Sonia, Leone, Filippo Elvino, Beishuizen, Bert, Rinket, Martin, Border, Natalie, Bos-Burgmeijer, Mariska, Braad, Astrid, Papendorp, S., Vermeijden, J., Pickkers, Peter, Van De A, Marieke, Van Wezel, Helen, Heunks, Leo, Bordar, Natalie, Luijten-Arts, Chantal, Hoedemaekers, Astrid, Van Der Hoeven, Hans, Roovers, Noortje, Hemelaar, Pleun, Intensive care medicine, ACS - Pulmonary hypertension & thrombosis, UCL - SSS/IREC/CARD - Pôle de recherche cardiovasculaire, UCL - SSS/IREC/MEDA - Pôle de médecine aiguë, and UCL - (SLuc) Service de soins intensifs
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Male ,medicine.medical_specialty ,Multiple Organ Failure ,MEDLINE ,lnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4] ,Critical Care and Intensive Care Medicine ,Sepsis ,03 medical and health sciences ,Adrenomedullin ,0302 clinical medicine ,Belgium ,Germany ,medicine ,Research Letter ,Humans ,Lactic Acid ,Hospital Mortality ,Prospective Studies ,Prospective cohort study ,Aged ,Netherlands ,Proportional Hazards Models ,Chi-Square Distribution ,business.industry ,lcsh:Medical emergencies. Critical care. Intensive care. First aid ,030208 emergency & critical care medicine ,lcsh:RC86-88.9 ,Length of Stay ,Middle Aged ,medicine.disease ,Prognosis ,Shock, Septic ,Survival Analysis ,3. Good health ,Hospitalization ,Patient Outcome Assessment ,Intensive Care Units ,030228 respiratory system ,Italy ,Shock (circulatory) ,Emergency medicine ,Female ,France ,medicine.symptom ,business ,Biomarkers - Abstract
Adrenomedullin (ADM) regulates vascular tone and endothelial permeability during sepsis. Levels of circulating biologically active ADM (bio-ADM) show an inverse relationship with blood pressure and a direct relationship with vasopressor requirement. In the present prospective observational multinational Adrenomedullin and Outcome in Sepsis and Septic Shock 1 (, AdrenOSS-1) study, we assessed relationships between circulating bio-ADM during the initial intensive care unit (ICU) stay and short-term outcome in order to eventually design a biomarker-guided randomized controlled trial.AdrenOSS-1 was a prospective observational multinational study. The primary outcome was 28-day mortality. Secondary outcomes included organ failure as defined by Sequential Organ Failure Assessment (SOFA) score, organ support with focus on vasopressor/inotropic use, and need for renal replacement therapy. AdrenOSS-1 included 583 patients admitted to the ICU with sepsis or septic shock.Circulating bio-ADM levels were measured upon admission and at day 2. Median bio-ADM concentration upon admission was 80.5 pg/ml [IQR 41.5-148.1 pg/ml]. Initial SOFA score was 7 [IQR 5-10], and 28-day mortality was 22%. We found marked associations between bio-ADM upon admission and 28-day mortality (unadjusted standardized HR 2.3 [CI 1.9-2.9]; adjusted HR 1.6 [CI 1.1-2.5]) and between bio-ADM levels and SOFA score (p0.0001). Need of vasopressor/inotrope, renal replacement therapy, and positive fluid balance were more prevalent in patients with a bio-ADM70 pg/ml upon admission than in those with bio-ADM ≤ 70 pg/ml. In patients with bio-ADM70 pg/ml upon admission, decrease in bio-ADM below 70 pg/ml at day 2 was associated with recovery of organ function at day 7 and better 28-day outcome (9.5% mortality). By contrast, persistently elevated bio-ADM at day 2 was associated with prolonged organ dysfunction and high 28-day mortality (38.1% mortality, HR 4.9, 95% CI 2.5-9.8).AdrenOSS-1 shows that early levels and rapid changes in bio-ADM estimate short-term outcome in sepsis and septic shock. These data are the backbone of the design of the biomarker-guided AdrenOSS-2 trial.ClinicalTrials.gov, NCT02393781 . Registered on March 19, 2015.
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- 2020
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27. Effects of oxidation on the hydrolysis by cholesterol esterase of sitosteryl esters as compared to a cholesteryl ester
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Julien-David, Diane, Ennahar, Saïd, Miesch, Michel, Geoffroy, Philippe, Raul, Francis, Aoude-Werner, Dalal, Lessinger, Jean-Marc, and Marchioni, Eric
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- 2008
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28. Part 8. Reference procedure for the measurement of catalytic concentration of α-amylase: [α-Amylase: 1,4-α-D-glucan 4-glucanohydrolase (AMY), EC 3.2.1.1]
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Schumann, Gerhard, Aoki, Ryoji, Ferrero, Carlo A., Ehlers, Glenn, Férard, Georges, Gella, F.-Javier, Jørgensen, Poul Jørgen, Kanno, Takahashi, Kessner, Art, Klauke, Rainer, Kytzia, Hans-Joachim, Lessinger, Jean-Marc, Miller, W. Gregory, Nagel, Rolf, Pauwels, Jean, Schimmel, Heinz, Siekmann, Lothar, Weidemann, Gerhard, Yoshida, Kiyoshi, and Ceriotti, Ferruccio
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- 2006
29. International Federation of Clinical Chemistry and Laboratory Medicine (IFCC): Scientific Division, Committee on Reference Systems for Enzymes (C-RSE)
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Schumann, Gerhard, Aoki, Ryoji, Ferrero, Carlo A., Ehlers, Glenn, Férard, Georges, Gella, F.-Javier, Jørgensen, Poul Jørgen, Kanno, Takahashi, Kessner, Art, Klauke, Rainer, Kytzia, Hans-Joachim, Lessinger, Jean-Marc, Miller, W. Gregory, Nagel, Rolf, Pauwels, Jean, Schimmel, Heinz, Siekmann, Lothar, Weidemann, Gerhard, Yoshida, Kiyoshi, and Ceriotti, Ferruccio
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- 2006
30. IFCC primary reference procedures for the measurement of catalytic activity concentrations of enzymes at 37°C
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Schumann, Gerhard, Aoki, Ryoji, Ferrero, Carlo A., Ehlers, Glenn, Férard, Georges, Gella, F. -Javier, Jørgensen, Poul Jørgen, Kanno, Takahashi, Kessner, Art, Klauke, Rainer, Kytzia, Hans-Joachim, Lessinger, Jean-Marc, Miller, W. Gregory, Nagel, Rolf, Pauwels, Jean, Schimmel, Heinz, Siekmann, Lothar, Weidemann, Gerhard, Yoshida, Kiyoshi, and Ceriotti, Ferruccio
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- 2006
31. Influence of human haptoglobin polymorphism on oxidative stress induced by free hemoglobin on red blood cells
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Guéye, Papa Madièye, Glasser, Nicole, Férard, Georges, and Lessinger, Jean-Marc
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- 2006
32. Intermethod calibration of alanine aminotransferase (ALT) and γ-glutamyltransferase (GGT) results: application to Fibrotest® and Actitest® scores
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Férard, Georges, Piton, Annie, Messous, Djamila, Imbert-Bismut, Francoise, Frairi, Asmaa, Poynard, Thierry, and Lessinger, Jean-Marc
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- 2006
33. A reference material for traceability of aspartate aminotransferase (AST) results
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Ferard, Georges, Imbert-Bismut, Francoise, Messous, Djamila, Piton, Annie, Ueda, Shigeru, Poynard, Thierry, and Lessinger, Jean-Marc
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- 2005
34. Determination of lipase catalytic activity in two reference materials: BCR 693 and BCR 694 by titrimetry at constant pH
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Lessinger, Jean-Marc, Parashou, Stella, Arzoglou, Panteleimon, Ramos, Paul, Chapus, Catherine, Dufaux, Jeanine, Junge, Wolfgang, Profilis, Christos, and Férard, Georges
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- 2004
35. Preparation and Characterization of Reference Materials for Human Pancreatic Lipase: BCR 693 (from Human Pancreatic Juice) and BCR 694 (Recombinant)
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Lessinger, Jean-Marc, Arzoglou, Pantaleimon, Ramos, Paul, Visvikis, Athanase, Parashou, Stella, Calam, Derek, Profilis, Christos, and Férard, Georges
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- 2003
36. Interleukin-6 chemiluminescent immunoassay on Lumipulse G600 II: analytical evaluation and comparison with three other laboratory analyzers
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Glady, Ludovic, primary, Lavaux, Thomas, additional, Charchour, Rim, additional, Lacorte, Jean-Marc, additional, and Lessinger, Jean-Marc, additional
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- 2020
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37. Optimizing Hydroxyurea Treatment for Sickle Cell Disease Patients: The Pharmacokinetic Approach
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Nazon, Charlotte, primary, Sabo, Amelia-Naomi, additional, Becker, Guillaume, additional, Lessinger, Jean-Marc, additional, Kemmel, Véronique, additional, and Paillard, Catherine, additional
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- 2019
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38. Atteintes myocardiques au cours de la maladie à coronavirus 19 (Covid-19) : principaux mécanismes physiopathologiques et utilité clinique des biomarqueurs cardiaques.
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Kamel, Said, Raynor, Alexandre, Zozor, Samuel, Lacape, Geneviève, Brunel, Valéry, Nivet-Antoine, Valérie, Collin-Chavagnac, Delphine, Peoc'h, Katell, Cohen, Ariel, Lassoued, Amin Ben, Chévrier, Marc, Alemann, Mathieu, Lessinger, Jean-Marc, Bérard, Annie M., Sapin, Vincent, Beauvieux, Marie-Christine, and Levy, Pacifique
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- 2021
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39. Circulating adrenomedullin estimates survival and reversibility of organ failure in sepsis: the prospective observational multinational Adrenomedullin and Outcome in Sepsis and Septic Shock-1 (AdrenOSS-1) study
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Mebazaa, Alexandre, Geven, Christopher, Bergmann, Andreas, Massat, Stéphanie, Desachy, Arnaud, Fally, Marie Anne, Robin, Laurence, Cracco, Christophe, Lafon, Charles, Calvat, Sylvie, Rouleau, Stéphane, Schnell, David, Lasocki, Sigismond, Antonelli, Massimo, Fesard, Philippe, Leblanc, Damien, Bouhours, Guillaume, Chassier, Claire, Conte, Mathieu, Gaillard, Thomas, Denou, Floriane, Kerymel, Mathieu, Guyon, Marion, Loiez, Anthéa, Beishuizen, Albertus, Lebreton, Stéphanie, Meziani, Ferhat, Allam, Hayat, Chenaf, Samir, Rahmani, Hassène, Heenen, Sarah, Kummerlen, Christine, Delabranche, Xavier, Boivin, Alexandra, Clere-Jehl, Raphaël, Constantin, Jean-Michel, Rabouël, Yannick, Pottecher, Julien, Bayer, Sophie, Metzger, Catherine, Hecketsweiler, Stéphane, Ludes, Pierre Olivier, Besancenot, Hortense, Dhif, Nadia, Freys, Guy, Lessinger, Jean-Marc, Damoisel, Charles, Launoy, Anne, Ruimy, Aude, Meyer, Alain, Szozot, M., Deye, Nicolas, Gayat, Etienne, Fournier, Marie-Céline, Abroug, Sarra, Louadah, Badr, Feliot, Elodie, Voicu, Sebastian, Malissin, I., Megarbane, Bruno, Manivet, Philippe, Victori, Gardianot, Kelly, Da Silva, La Foucher, Béatrice, Pierre, Valérie, Kerdjana, Lamia, Di Somma, Salvatore, Beeken, Thomas, Goury, Antoine, Garcon, Pierre, Gaugain, Samuel, Chousterman, Benjamin Glen, Huot, Benjamin, Barthelemy, Romain, Soyer, Benjamin, Jacob, Laurent, Legrand, Matthieu, Dugernier, Thierry, Bonnet, Francine, Legall, Chloé, Oueslati, Haikel, Cupaciu, Alexandru, Sonneville, Romain, Letrou, Sophie, Bouadma, Lila, François, Bruno, Mourvillier, Bruno, Deiler, Véronique, Magalhaes, Eric, Neuville, Mathilde, Timsit, Jean-François, Radjou, Aguila, Gaudry, Stéphane, Dubief, Emeline, Messika, Jonathan, La Combe, Béatrice, Gaudry, Stephane, Roux, Damien, Berquier, Guillaume, Laissi, Mohamed, Ricard, Jean-Damien, Perbet, Sebastien, Delmas, Julie, Pascal, Julien, Cayot, Sophie, Guerin, Renaud, Hollinger, Alexa, Huberlant, Vincent, Jabaudon, Matthieu, Roszyk, Laurence, Rolhion, Christine, Bourdier, Justine, Lematte, Mathilde, Gouhier, Charlène, Verlhac, Camille, Godet, Thomas, Radji, Sophiano, Caumon, Elodie, Lascarrou, Jean-Baptiste, Thibault, Sandrine, Marx, Nikolaus, Schuerholz, Tobias, Pezechk, Jessica, Feld, Florian, Brülls, Christian, Beeker, Thorben, Simon, Tim-Philipp, Deisz, Robert, Schindler, Achim, Marx, Gernot, Meier, Bianca, Janisch, Thorsten, Hohn, Andreas, Schedler, Dirk, Wetsch, Wolfgang, Schröder, Daniel, Meier-Hellmann, Andreas, Lucht, Alexander, Henker, Robert, Römmer, Magdalena, Mercier, Emmanuelle, Meinig, Torsten, Zacharowski, Kai D., Meybohm, Patrick, Lindau, Simone, Mutlak, Haitham, Kluge, Stefan, Ringeis, Grit, Füllekrug, Birgit, Singer, Brigitte, Nierhaus, Axel, Bangert, Katrin, de Heer, Geraldine, Frings, Daniel, Fuhrmann, Valentin, Müller, Jakob, Schreiber, Jörg, Sensen, Barbara, Siedler, Stephanie, Siewecke, Annekatrin, Söffker, Gerold, Pickkers, Peter, Wichmann, Dominic, Kerinn, Mélanie, Jaschinski, Ulrich, Kreuser, Ilse, Zanquila, Marlene, Kortgen, Andreas, Bloos, Frank, Gonnert, Falk, Thomas-Rüddel, Daniel, Haucke, Anja, Kolanos, Steffi, Kohlberg, Karina Knuhr, Bloos, Petra, Schwope, Katrin, Rossella, Marino, Russo, Veronica, Simona, Santarelli, Bartoli, Christopher, Navarin, Sylvia, Bongiovanni, Cristina, Orru, Michela, Quatrocchi, Daniela, Zoccoli, Giada, Varchetta, Antonella, de Pascale, Gennaro, Vallecoccia, Maria Sole, Cutuli, Salvatore Lucio, Digravio, Valentina, Laterre, Pierre-François, Quattrochi, Daniela, D'Arrigo, Sonia, Leone, Filippo Elvino, Beishuizen, Bert, Rinket, Martin, Border, Natalie, Bos-Burgmeijer, Mariska, Braad, Astrid, Papendorp, S., Cornet, Alexander, AdrenOSS-1 study investigators, Vermeijden, J., Trof, Ronald J., van de A, Marieke, Van Wezel, Helen, Heunks, Leo, Luijten-Arts, Chantal, Hoedemaekers, Astrid, van der Hoeven, Hans, Wittebole, Xavier, Laterre, Pierre François, Roovers, Noortje, Hemelaar, Pleun, Berghe, Caroline, Dujardin, Marie-France, Renard, Suzanne, Collienne, Christine, Zapatero, Diego Castanares, Vinetti, Marco, De Schryver, Nicolas, Thirifays, Anne, Mairesse, Jacques, Petre, Hélène, Buelens, Isabelle, Henin, Pierre, Trine, Hugues, Laurent, Yves, Sébastien, Loix, Geukens, Paul, Blet, Alice, Kehl, Laurent, Vignon, Philippe, Pichon, Nicolas, Begot, Emmanuelle, Fedou, Anne-Laure, Chapellas, Catherine, Galy, Antoine, Rodier, Nicolas, Baudrillart, Ludmilla, Nouaille, Michelle, Laleu, Séverine, Mancia, Claire, Daix, Thomas, Bourzeix, Paul, Herafa, Isabelle, Duchambon, Anne-Aurore, Lascarrou, Jean Baptiste, Fiancette, Maud, Colin, Gwenhael, Hartmann, Oliver, Henry-Lagarrigue, Matthieu, Lacherade, Jean-Claude, Lebert, Christine, Martin-Levèvre, Laurent, Vinatier, Isabelle, Yehia, Aihem, Bachoumas, Konstantinos, Joret, Aurélie, Reignier, Jean, Rousseau, Cécille, Scigalla, Paul, Maquigneau, Natacha, Alcourt, Yolaine, Zinzonni, Vanessa Erragne, Deschamps, Angélique, Robert, Angelina, Simeon-Vieules, Véronique, Aubrey, Aurélie, Mabilat, Christine, Garot, Denis, Struck, Joachim, Ehrmann, Stephan, Legras, Annick, Manikikian, Jouan, Youenn, Dequin, Pierre François, Guillon, Antoine, Bodet-Contentin, Laetitia, Rouve, Emmannuelle, Salmon, Charlotte, Brick, Lysiane, Department of Anaesthesiology and Critical Care and Burn Unit, St-Louis Hospital, Service de biochimie INSERM UMR-S942, Hôpital Lariboisière-APHP, Université Paris Diderot - Paris 7 (UPD7), Hôpitaux Universitaires Saint-Louis, Lariboisière, Fernand-Widal, Biomarqueurs CArdioNeuroVASCulaires (BioCANVAS), Université Paris 13 (UP13)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM), Cliniques universitaires St Luc [Bruxelles], Hopital Saint-Louis [AP-HP] (AP-HP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Adrenomed AG, Service de Médecine Intensive et Réanimation [CHU Clermont-Ferrand], CHU Gabriel Montpied [Clermont-Ferrand], CHU Clermont-Ferrand-CHU Clermont-Ferrand, Génétique, Reproduction et Développement (GReD), Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Institut National de la Santé et de la Recherche Médicale (INSERM), Groupe Hospitalier Saint Louis - Lariboisière - Fernand Widal [Paris], Department of Intensive Care, St-Pierre Hospital, Centre d'Investigation Clinique de Limoges (CIC1435), CHU Limoges-Institut National de la Santé et de la Recherche Médicale (INSERM), CHU Tenon [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Service de Réanimation Médico-Chirurgicale [Avicenne], Université Paris 13 (UP13)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Avicenne [AP-HP], Service de réanimation médicale [CHU Nantes], Centre hospitalier universitaire de Nantes (CHU Nantes), Rheinisch-Westfälische Technische Hochschule Aachen (RWTH), Centre Hospitalier Régional Universitaire de Tours (CHRU TOURS), Hôpital Saint-Louis, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Diderot - Paris 7 (UPD7), Radboud university [Nijmegen], Hôpital Bichat - Claude Bernard, Université Catholique de Louvain = Catholic University of Louvain (UCL), Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM), Physiopathologie Cardiovasculaire et Mitochondriale (MITOVASC), Université d'Angers (UA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Intensive care medicine, Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Centre National de la Recherche Scientifique (CNRS), Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Limoges, Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Rheinisch-Westfälische Technische Hochschule Aachen University (RWTH), Radboud University [Nijmegen], and MitoVasc - Physiopathologie Cardiovasculaire et Mitochondriale (MITOVASC)
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Male ,medicine.medical_treatment ,[SDV]Life Sciences [q-bio] ,lnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4] ,030204 cardiovascular system & hematology ,Critical Care and Intensive Care Medicine ,Medical and Health Sciences ,law.invention ,Adrenomedullin ,0302 clinical medicine ,Belgium ,law ,Germany ,Medicine ,Hospital Mortality ,Prospective Studies ,Netherlands ,Outcome ,lcsh:Medical emergencies. Critical care. Intensive care. First aid ,Hematology ,Middle Aged ,Prognosis ,Shock, Septic ,Intensive care unit ,3. Good health ,Hospitalization ,Intensive Care Units ,Infectious Diseases ,Italy ,Anesthesia ,outcome ,biomarker ,Female ,SOFA score ,France ,medicine.symptom ,Infection ,Multiple Organ Failure ,Sepsis ,03 medical and health sciences ,All institutes and research themes of the Radboud University Medical Center ,Clinical Research ,Biomarker ,Sepsis-2 ,Sepsis-3 ,Aged ,Biomarkers ,Chi-Square Distribution ,Humans ,Length of Stay ,Patient Outcome Assessment ,Proportional Hazards Models ,Survival Analysis ,Settore MED/41 - ANESTESIOLOGIA ,AdrenOSS-1 study investigators ,Lactic Acid ,Renal replacement therapy ,business.industry ,Septic shock ,Research ,Inflammatory and immune system ,Organ dysfunction ,030208 emergency & critical care medicine ,lcsh:RC86-88.9 ,medicine.disease ,Emergency & Critical Care Medicine ,Good Health and Well Being ,Blood pressure ,business - Abstract
Background Adrenomedullin (ADM) regulates vascular tone and endothelial permeability during sepsis. Levels of circulating biologically active ADM (bio-ADM) show an inverse relationship with blood pressure and a direct relationship with vasopressor requirement. In the present prospective observational multinational Adrenomedullin and Outcome in Sepsis and Septic Shock 1 (, AdrenOSS-1) study, we assessed relationships between circulating bio-ADM during the initial intensive care unit (ICU) stay and short-term outcome in order to eventually design a biomarker-guided randomized controlled trial. Methods AdrenOSS-1 was a prospective observational multinational study. The primary outcome was 28-day mortality. Secondary outcomes included organ failure as defined by Sequential Organ Failure Assessment (SOFA) score, organ support with focus on vasopressor/inotropic use, and need for renal replacement therapy. AdrenOSS-1 included 583 patients admitted to the ICU with sepsis or septic shock. Results Circulating bio-ADM levels were measured upon admission and at day 2. Median bio-ADM concentration upon admission was 80.5 pg/ml [IQR 41.5–148.1 pg/ml]. Initial SOFA score was 7 [IQR 5–10], and 28-day mortality was 22%. We found marked associations between bio-ADM upon admission and 28-day mortality (unadjusted standardized HR 2.3 [CI 1.9–2.9]; adjusted HR 1.6 [CI 1.1–2.5]) and between bio-ADM levels and SOFA score (p < 0.0001). Need of vasopressor/inotrope, renal replacement therapy, and positive fluid balance were more prevalent in patients with a bio-ADM > 70 pg/ml upon admission than in those with bio-ADM ≤ 70 pg/ml. In patients with bio-ADM > 70 pg/ml upon admission, decrease in bio-ADM below 70 pg/ml at day 2 was associated with recovery of organ function at day 7 and better 28-day outcome (9.5% mortality). By contrast, persistently elevated bio-ADM at day 2 was associated with prolonged organ dysfunction and high 28-day mortality (38.1% mortality, HR 4.9, 95% CI 2.5–9.8). Conclusions AdrenOSS-1 shows that early levels and rapid changes in bio-ADM estimate short-term outcome in sepsis and septic shock. These data are the backbone of the design of the biomarker-guided AdrenOSS-2 trial. Trial registration ClinicalTrials.gov, NCT02393781. Registered on March 19, 2015. Electronic supplementary material The online version of this article (10.1186/s13054-018-2243-2) contains supplementary material, which is available to authorized users.
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- 2018
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40. A novel machine learning-derived decision tree including uPA/PAI-1 for breast cancer care
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Reix, Nathalie, primary, Lodi, Massimo, additional, Jankowski, Stéphane, additional, Molière, Sébastien, additional, Luporsi, Elisabeth, additional, Leblanc, Suzanne, additional, Scheer, Louise, additional, Ibnouhsein, Issam, additional, Benabu, Julie-Charlotte, additional, Gabriele, Victor, additional, Guggiola, Alberto, additional, Lessinger, Jean-Marc, additional, Chenard, Marie-Pierre, additional, Alpy, Fabien, additional, Bellocq, Jean-Pierre, additional, Neuberger, Karl, additional, Tomasetto, Catherine, additional, and Mathelin, Carole, additional
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- 2018
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41. Commutability Assessment of Candidate Reference Materials for Pancreatic α-Amylase
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Deprez, Liesbet, primary, Toussaint, Brigitte, primary, Zegers, Ingrid, primary, Schimmel, Heinz, primary, Grote-Koska, Denis, primary, Klauke, Rainer, primary, Gella, F Javier, primary, Orth, Matthias, primary, Lessinger, Jean-Marc, primary, Trenti, Tommaso, primary, Nilsson, Göran, primary, and Ceriotti, Ferruccio, primary
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- 2018
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42. Time-resolved fluorescence allows selective monitoring of Trp30 environmental changes in the seven-Trp-containing human pancreatic lipase
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Ramos, Paul, Coste, Thierry, Piemont, Etienne, Lessinger, Jean Marc, Bousquet, Jean Alain, Chapus, Catherine, Kerfelec, Brigitte, Ferard, Georges, and Mely, Yves
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Fluorescence -- Research ,Pancreatic beta cells -- Research ,Biological sciences ,Chemistry - Abstract
The steady-state and time-resolved fluoresence parameters of five single-point mutants in which one Trp residue was substituted with a weakly fluorescent Phe residue is investigated. It was found that Trp residues at positions 17 and 402 strongly contributed to the 1.61 ns lifetime of HPL, while Trp residues at positions 86 and 252 contributed to the 0.29 ns lifetime.
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- 2003
43. A novel machine learning-derived decision tree including uPA/PAI-1 for breast cancer care.
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Reix, Nathalie, Lodi, Massimo, Jankowski, Stéphane, Molière, Sébastien, Luporsi, Elisabeth, Leblanc, Suzanne, Scheer, Louise, Ibnouhsein, Issam, Benabu, Julie-Charlotte, Gabriele, Victor, Guggiola, Alberto, Lessinger, Jean-Marc, Chenard, Marie-Pierre, Alpy, Fabien, Bellocq, Jean-Pierre, Neuberger, Karl, Tomasetto, Catherine, and Mathelin, Carole
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BREAST cancer ,HORMONE receptor positive breast cancer ,CANCER chemotherapy ,MACHINE learning ,BIOMARKERS - Abstract
Background: uPA and PAI-1 are breast cancer biomarkers that evaluate the benefit of chemotherapy (CT) for HER2-negative, estrogen receptor-positive, low or intermediate grade patients. Our objectives were to observe clinical routine use of uPA/PAI-1 and to build a new therapeutic decision tree integrating uPA/PAI-1. Methods: We observed the concordance between CT indications proposed by a canonical decision tree representative of French practices (not including uPA/PAI-1) and actual CT prescriptions decided by a medical board which included uPA/PAI-1. We used a method of machine learning for the analysis of concordant and non-concordant CT prescriptions to generate a novel scheme for CT indications. Results: We observed a concordance rate of 71% between indications proposed by the canonical decision tree and actual prescriptions. Discrepancies were due to CT contraindications, high tumor grade and uPA/PAI-1 level. Altogether, uPA/PAI-1 were a decisive factor for the final decision in 17% of cases by avoiding CT prescription in two-thirds of cases and inducing CT in other cases. Remarkably, we noted that in routine practice, elevated uPA/PAI-1 levels seem not to be considered as a sufficient indication for CT for N≤3, Ki 67≤30% tumors, but are considered in association with at least one additional marker such as Ki 67>14%, vascular invasion and ER-H score <150. Conclusions: This study highlights that in the routine clinical practice uPA/PAI-1 are never used as the sole indication for CT. Combined with other routinely used biomarkers, uPA/PAI-1 present an added value to orientate the therapeutic choice. [ABSTRACT FROM AUTHOR]
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- 2019
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44. Amélioration continue du DES de biologie médicale à l’aide d’un carnet de stage et d’un questionnaire d’évaluation de la satisfaction. [= Clinical laboratory medicine: continuous amelioration with a book of objectives and satisfaction survey]
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Reix, Nathalie, Agin, Arnaud, Bahram, Seiamak, Dali-Youcef, Nassim, Grucker, Daniel, Jaulhac, Benoit, Lepiller, Quentin, Lessinger, Jean-Marc, Mauvieux, Laurent, Monier, Laurie, Schramm, Frederic, Stoll-Keller, Françoise, Vallat, Laurent, Ludes, Bertrand, Candolfi, Ermanno, Filisetti, Denis, Laboratoire des sciences de l'ingénieur, de l'informatique et de l'imagerie (ICube), École Nationale du Génie de l'Eau et de l'Environnement de Strasbourg (ENGEES)-Université de Strasbourg (UNISTRA)-Institut National des Sciences Appliquées - Strasbourg (INSA Strasbourg), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Institut National de Recherche en Informatique et en Automatique (Inria)-Les Hôpitaux Universitaires de Strasbourg (HUS)-Centre National de la Recherche Scientifique (CNRS)-Matériaux et Nanosciences Grand-Est (MNGE), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Réseau nanophotonique et optique, Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Immuno-Rhumatologie Moléculaire, Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Laboratoire de Bioimagerie et Pathologies (LBP), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Anthropologie Moléculaire et Imagerie de Synthèse (AMIS), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS), Dynamique des interactions Hôte pathogène, Université de Strasbourg (UNISTRA), Institut National des Sciences Appliquées - Strasbourg (INSA Strasbourg), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS)-École Nationale du Génie de l'Eau et de l'Environnement de Strasbourg (ENGEES)-Réseau nanophotonique et optique, Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Matériaux et nanosciences d'Alsace (FMNGE), Institut de Chimie du CNRS (INC)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Strasbourg (UNISTRA), and Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)
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book of objectives ,objectives ,satisfaction survey ,improvement ,[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology ,medical biology training - Abstract
We report in this publication the use of two educational tools, a questionnaire of satisfaction and a training book, to improve the training of students during their internship in clinical laboratory at the "Pôle de biologie des Hôpitaux universitaires de Strasbourg" in France. First, the ongoing training was assessed by the interns with a questionnaire measuring satisfaction. The analysis of this questionnaire identified four key points to improve: 1) define the teaching objectives, 2) organize the training with a schedule, 3) revise certain teaching methods and 4) ensure better integration of the students in the team of medical biologists. After this assessment, we implemented a training book to answer these four points. Indeed, the training book presents the objectives, the schedule of training, and how to validate the educational objectives. A new assessment was performed again using the same methodology. Results showed an improvement in student satisfaction from 74 to 88 %. The questionnaire of satisfaction and the training book are presented in this article. The aim of the assessment of training combined with the training book is to incite the actors of the training (students and teachers) to continually improve the training. The objectives of the Pôle de Biologie are to obtain an 80 % satisfaction rate during the 6 months trainings and to reduce or eliminate dissatisfaction, and finally to ensure the validation by students of 80 to 100 % of their predetermined objectives.
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- 2015
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45. Prognosis of patients with severe hyponatraemia is related not only to hyponatraemia but also to comorbidities and to medical management: results of an observational retrospective study
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Krummel, Thierry, primary, Prinz, Eric, additional, Metten, Marie-Astrid, additional, Borni-Duval, Claire, additional, Bazin-Kara, Dorothée, additional, Charlin, Emmanuelle, additional, Lessinger, Jean-Marc, additional, and Hannedouche, Thierry, additional
- Published
- 2016
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46. Clinical laboratory medicine: continuous amelioration with a book of objectives and satisfaction survey
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Reix, Nathalie, additional, Agin, Arnaud, additional, Bahram, Seiamak, additional, Dali-Youcef, Nassim, additional, Grucker, Daniel, additional, Jaulhac, Benoît, additional, Lepiller, Quentin, additional, Lessinger, Jean-Marc, additional, Mauvieux, Laurent, additional, Monier, Laurie, additional, Schramm, Frédéric, additional, Stoll-Keller, Françoise, additional, Vallat, Laurent, additional, Ludes, Bertrand, additional, Candolfi, Ermanno, additional, and Filisetti, Denis, additional
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- 2015
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47. High severe acute respiratory coronavirus virus 2 (SARS-CoV-2) seroconversion rate among geriatric staff from Strasbourg University Hospitals
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Panaget, Baptiste, Velay, Aurélie, Gontard, Louise, Severac, François, Meyer, Maxence, Antoni, Elisabeth, Kaltenbach, Georges, Kling-Pillitteri, Laurence, Sammour, Yasmine, Hansmann, Yves, Hernandez, Céline, Lavigne, Thierry, Lessinger, Jean-Marc, Gonzalez, Maria, Wendling, Marie-Josée, Gallais, Floriane, Kepka, Sabrina Garnier, and Fafi-Kremer, Samira
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- 2022
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48. Analysis of the RNA chaperoning activity of the hepatitis C virus core protein on the conserved 3′X region of the viral genome
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Sharma, Kamal Kant, primary, de Rocquigny, Hugues, additional, Darlix, Jean Luc, additional, Lavergne, Jean-Pierre, additional, Pénin, François, additional, Lessinger, Jean-Marc, additional, and Mély, Yves, additional
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- 2011
- Full Text
- View/download PDF
49. IFCC primary reference procedures for the measurement of catalytic activity concentrations of enzymes at 37 °C. Part 9: Reference procedure for the measurement of catalytic concentration of alkaline phosphatase
- Author
-
Schumann, Gerhard, primary, Klauke, Rainer, additional, Canalias, Francesca, additional, Bossert-Reuther, Steffen, additional, F.H. Franck, Paul, additional, Gella, F.-Javier, additional, J. Jørgensen, Poul, additional, Kang, Dongchon, additional, Lessinger, Jean-Marc, additional, Panteghini, Mauro, additional, and Ceriotti, Ferruccio, additional
- Published
- 2011
- Full Text
- View/download PDF
50. Evaluation of Commutability of Control Materials
- Author
-
Brion, Emmanuel, primary, Lessinger, Jean-Marc, additional, Gould, Nicholas, additional, Leyendecker, Jacky, additional, and Férard, Georges, additional
- Published
- 2002
- Full Text
- View/download PDF
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