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Fungal infections are one of the most prominent infection and causes a wide number of disease. It occurs in almost every person once in their life. Leonotis nepetaefolia (L) R.Br. belongs to the genus Leonotis and family Lamiaceae. It is native to tropical Africa and India. The flowers of the plant are used medicinally for the treatment of several skin infections. The present paper deals with the antifungal activity of flowers of the selected plant. PEE, CE, EE and AE of flowers of Leonotis nepetaefolia were evaluated for anti-fungal activity and zone of inhibition were recorded. [ABSTRACT FROM AUTHOR]

La especie Leonotis nepetaefolia (Linn) R.Br., conocida como Bastón de San Francisco, se ha utilizado en Cuba con propósitos medicinales y ornamentales. Sin embargo, no se ha informado la composición de ácidos grasos (AG) del aceite obtenido de las semillas de esta especie en el país. Teniendo en cuenta lo anterior, el objetivo del trabajo fue determinar los AG constituyentes del aceite de las semillas de L. nepetaefolia. A tales efectos, una cantidad de ellas se recolectó, trituró y se extrajo con hexano en un baño ultrasónico. Los extractos (n = 2) fueron filtrados y el disolvente fue evaporado en un evaporador rotatorio a 60 °C y al vacío. Se determinaron las características organolépticas y los rendimientos de extracción. El contenido de AG analizados como ésteres metílicos, se determinó por cromatografía de gases con columna capilar BPX-70 y detector de ionización por llama. Se obtuvo un aceite [28,2 % (m/m)] amarillo claro de olor característico. Los principales AG encontrados fueron el oleico (C18:1 n-9; 43,2 %), labalénico (C18:2 n-5,6; 18,4 %), palmítico (C16:0; 15,0 %), linoleco (C18:2 n-9,12; 13,4 %), y esteárico (C18:0; 5,7 %), mientras que otros ácidos grasos como C12:0 al C16:0, C16:1 (n-7 y n-9), C17:0, C18:1 (n-7), C18:3 (n-9,12,15), C20:0, C20:1 (n-11), C22:0, y C24:0, se encontraron en proporciones < 1 %. De manera general, el contenido de AG coincidió con lo descrito en la literatura para esta especie. Estos resultados constituyen el primer estudio de la composición química de esta especie en Cuba y pudieran contribuir a sustentar sus posibles usos nutricionales y medicinales.

Leonotis nepetaefolia (L.) R.Br. specie, known as Bastón de San Francisco, has been used in Cuba for medicinal and ornamental purposes. However, the fatty acid (FA) composition of the seed oil obtained from this species in our country has not been reported. Taking into account these facts, the aim of this work was to determine the FA constituents of L. nepetaefolia seeds oil. Seeds were collected, milled and extracted with hexane in an ultrasonic bath. The extracts (n=2) were filtered and the solvent was evaporated under reduced pressure in a rotary evaporator at 60 °C. Organoleptic characteristics and extraction yields of the oils were determined. The content of FAs, analysed as methyl esters, were determined by gas chromatography with a BPX-70 capillary column and a flame ionization detector. A light yellow oil with peculiar odor was obtained, yielding 28.2% (w/w). The main FAs found were oleic (C18:1 n-9; 43,2%), laballenic (C18:2 n-5,6; 18,4%), palmitic (C16:0; 15,0%), linoleic (C18:2 n-9,12; 13,4%), and stearic (C18:0; 5,7%), while other fatty acids, such as C12:0 to C16:0, C16:1 (n-7 y n-9), C17:0, C18:1 (n-7), C18:3 (n-9,12,15), C20:0, C20:1 (n-11), C22:0, and C24:0 were found in proportions < 1%. Overall, the FAs content is in good agreement with that described in literature for this species. These results represent the first study of the chemical composition of the oil from this species growing in Cuba and could contribute to support its potential medicinal and nutritional uses. [ABSTRACT FROM AUTHOR]