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6. Penile Cancer

Author

Leone, Andrew R., primary, Abdo, Nicole, additional, Diorio, Gregory J., additional, and Spiess, Philippe E., additional

Published
2017
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8. Contemporary issues surrounding small renal masses: evaluation, diagnostic biopsy, nephron sparing, and novel treatment modalities

Author

Leone, Andrew R., Diorio, Gregory J., Spiess, Philippe E., and Gilbert, Scott M.

Subjects
Kidney cancer -- Diagnosis -- Care and treatment, Biological markers -- Identification and classification, Diagnostic imaging -- Innovations, Health
Abstract

Incidental identification of small renal masses (SRMs) has become increasingly common with widespread adoption of cross-sectional imaging. To date, early detection of SRMs has not translated to a substantial improvement in cancer-specific survival. Guidelines on the management of SRMs are evolving to reflect recent developments in treatment. The major approaches to managing SRMs include active surveillance, partial/radical nephrectomy, and ablative therapies, such as radiofrequency ablation with cryoablation. The goal of treatment is to optimize oncologic and renal function outcomes while avoiding overtreatment and associated morbidity. In this review, we summarize the diagnosis of SRMs, the role of renal mass biopsy, different treatment strategies, and future directions, including emerging molecular biomarkers., Evaluation and management of small renal masses (SRMs)-defined as enhancing renal masses < 4 cm on axial imaging --have become important clinical issues in recent years, particularly in light of [...]

Published
2016

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