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Your search keyword '"Leonardi, Gianluca"' showing total 26 results
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26 results on '"Leonardi, Gianluca"'

5. Increase of continuous treatments and regional citrate anticoagulation during renal replacement therapy in the ICUs of the North-West of Italy from 2007 to 2015

Author

Mariano, Filippo, Inguaggiato, Paola, Pozzato, Marco, Turello, Ernesto, David, Paola, Berutti, Silvia, Manes, Massimo, Leonardi, Gianluca, Gai, Massimo, Mella, Alberto, Canepari, Giorgio, Forneris, Giacomo, Storace, Giulia, Brustia, Maddalena, Pellù, Valentina, Consiglio, Valentina, Tognarelli, Giuliana, Bonaudo, Roberto, Gianoglio, Bruno, Campo, Andrea, Viglino, Giusto, Marino, Angela, Maffei, Stefano, Roscini, Elisabetta, Calabrese, Giovanni, Gherzi, Mauro, Formica, Marco, Stramignoni, Emanuele, Salomone, Mario, Martina, Guido, Serra, Andrea, Deagostini, Chiara, Savoldi, Silvana, Marciello, Antonio, Todini, Vincenzo, Chiappero, Fabio, Vio, Patrizia, Borzumati, Maurizio, Costantini, Luigina, Filiberti, Oliviero, Cesano, Giulio, Boero, Roberto, Vitale, Corrado, Chiarinotti, Doriana, Manganaro, Marco, Besso, Luca, Cusinato, Stefano, Roccatello, Dario, and Biancone, Luigi

Subjects
Nephrology, Urology
Abstract

Few reports have addressed the change in Renal Replacement Therapy (RRT) management in the ICUs over the years in western countries. This study aims to assess the trend of dialytic practice in a 4.5-million population-based study of the northwest of Italy.A nine-year survey covering all the RRT provided in the ICUs. Consultant nephrologists of the 26 Nephrology and Dialysis centers reported their activities in the years 2007, 2009, 2012, and 2015.From 2007 to 2015 the patients treated increased from 1042 to 1139, and the incidence of RRT from 254 to 263 cases/10^6 inhabitants. The workload for Dialysis Center was higher in the larger hub hospitals. RRT for Acute Kidney Injury (AKI), continuation of treatment in chronically dialyzed patients, or extrarenal indications accounted for about the stable rate of 70, 25 and 5% of all RRT sessions, respectively. Continuous modality days increased from 2731 days (39.5%) in 2007 to 5076 (70.6%) in 2015, when the continuous+prolonged treatment days were 6880/7196 (95.6% of total days). As to RRT timing, in 2015 only the classical clinical criteria, and no K-DIGO stage were adopted by most Centers. As to RRT interruption, in 2015 urine volume was the first criterion. Implementation of citrate anticoagulation (RCA) for RRT patients significantly increased from 2.8% in 2007 to 30.9% in 2015, when it was applied in all 26 Centers.From 2007 to 2015, current practice has changed towards shared protocols, with increasing continuous modality and RCA implementation.

Published
2023

7. Increase of continuous treatments and regional citrate anticoagulation during renal replacement therapy in the ICUs of the north-west of Italy from 2007 to 2015

Author

MARIANO, Filippo, primary, INGUAGGIATO, Paola, additional, POZZATO, Marco, additional, TURELLO, Ernesto, additional, DAVID, Paola, additional, BERUTTI, Silvia, additional, MANES, Massimo, additional, LEONARDI, Gianluca, additional, GAI, Massimo, additional, MELLA, Alberto, additional, CANEPARI, Giorgio, additional, FORNERIS, Giacomo, additional, STORACE, Giulia, additional, BRUSTIA, Maddalena, additional, PELLÙ, Valentina, additional, CONSIGLIO, Valentina, additional, TOGNARELLI, Giuliana, additional, BONAUDO, Roberto, additional, GIANOGLIO, Bruno, additional, CAMPO, Andrea, additional, VIGLINO, Giusto, additional, MARINO, Angela, additional, MAFFEI, Stefano, additional, ROSCINI, Elisabetta, additional, CALABRESE, Giovanni, additional, GHERZI, Mauro, additional, FORMICA, Marco, additional, STRAMIGNONI, Emanuele, additional, SALOMONE, Mario, additional, MARTINA, Guido, additional, SERRA, Andrea, additional, DEAGOSTINI, Chiara, additional, SAVOLDI, Silvana, additional, MARCIELLO, Antonio, additional, TODINI, Vincenzo, additional, CHIAPPERO, Fabio, additional, VIO, Patrizia, additional, BORZUMATI, Maurizio, additional, COSTANTINI, Luigina, additional, FILIBERTI, Oliviero, additional, CESANO, Giulio, additional, BOERO, Roberto, additional, VITALE, Corrado, additional, CHIARINOTTI, Doriana, additional, MANGANARO, Marco, additional, BESSO, Luca, additional, CUSINATO, Stefano, additional, ROCCATELLO, Dario, additional, and BIANCONE, Luigi, additional

Published
2022
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8. Assessment of Phasic Changes of Vascular Size by Automated Edge Tracking-State of the Art and Clinical Perspectives

Author

Mesin, Luca, primary, Albani, Stefano, additional, Policastro, Piero, additional, Pasquero, Paolo, additional, Porta, Massimo, additional, Melchiorri, Chiara, additional, Leonardi, Gianluca, additional, Albera, Carlo, additional, Scacciatella, Paolo, additional, Pellicori, Pierpaolo, additional, Stolfo, Davide, additional, Grillo, Andrea, additional, Fabris, Bruno, additional, Bini, Roberto, additional, Giannoni, Alberto, additional, Pepe, Antonio, additional, Ermini, Leonardo, additional, Seddone, Stefano, additional, Sinagra, Gianfranco, additional, Antonini-Canterin, Francesco, additional, and Roatta, Silvestro, additional

Published
2022
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10. Additional file 1 of Clinical outcomes and temporal trends of immunological and non-immunological rare diseases in adult kidney transplant

Author

Gallo, Ester, Mingozzi, Silvia, Mella, Alberto, Fop, Fabrizio, Presta, Roberto, Burdese, Manuel, Boaglio, Elena, Torazza, Maria Cristina, Giraudi, Roberta, Leonardi, Gianluca, Lavacca, Antonio, Gontero, Paolo, Sedigh, Omidreza, Bosio, Andrea, Verri, Aldo, Dolla, Caterina, and Biancone, Luigi

Abstract

Additional file 1: Table S1. Rare disease classification (according to Orpha-code) in the studied population. Table S2. Baseline characteristics and renal function tests among the most frequent RDs subgroups of the studied population.

Published
2021
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11. NOVEL AND KNOWN MUTATIONS IDENTIFIED BY CLINICAL EXOME SEQUENCING FOR THE DIAGNOSIS OF POLYCYSTIC KIDNEY DISEASE

Author

Vaisitti, Tiziana, Sorbini, Monica, Callegari, Martina, Kalantari, Silvia, Bracciama, Valeria, Arruga, Francesca, Vanzino, Silvia Bruna, Pelle, Alessandra, Giachino, Daniela, Cocchi, Enrico, Simone Baldovino, Rollino, Cristiana, Fenoglio, Roberta, Tamagnone, Michela, Gherzi, Maurizio, Soragna, Giorgio, Vitale, Corrado, Berta, Valentina, Calabrese, Giovanni, Leonardi, Gianluca, Biancone, Luigi, Strampelli, Emanuela, Maroni, Serena, Santi, Sonia, Funaro, Loredana, Borzumati, Maurizio, Bertinetto, Patrizia, Viglino, Giusto, Gianoglio, Bruno, Peruzzi, Licia, Roccatello, Dario, Amoroso, Antonio, and Deaglio, Silvia

Published
2020

14. P0051NOVEL AND KNOWN MUTATIONS IDENTIFIED BY CLINICAL EXOME SEQUENCING FOR THE DIAGNOSIS OF POLYCYSTIC KIDNEY DISEASE

Author

Vaisitti, Tiziana, primary, Sorbini, Monica, primary, Callegari, Martina, primary, Kalantari, Silvia, primary, Bracciamà, Valeria, primary, Arruga, Francesca, primary, Vanzino, Silvia Bruna, primary, Pelle, Alessandra, primary, Giachino, Daniela, primary, Cocchi, Enrico, primary, Baldovino, Simone, primary, Rollino, Cristiana, primary, Fenoglio, Roberta, primary, Tamagnone, Michela, primary, Gherzi, Maurizio, primary, Soragna, Giorgio, primary, Vitale, Corrado, primary, Berta, Valentina, primary, Calabrese, Giovanni, primary, Leonardi, Gianluca, primary, Biancone, Luigi, primary, Strampelli, Emanuela, primary, Maroni, Serena, primary, Santi, Sonia, primary, Funaro, Loredana, primary, Borzumati, Maurizio, primary, Bertinetto, Patrizia, primary, Viglino, Giusto, primary, Gianoglio, Bruno, primary, Peruzzi, Licia, primary, Roccatello, Dario, primary, Amoroso, Antonio, primary, and Deaglio, Silvia, primary

Published
2020
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15. A comparative study on the electrical and gas sensing properties of thick films prepared with synthesized nano-sized and commercial micro-sized Fe2O3 powders

Author

Maryam Bonyani, Giovani Neri, Shahab Torkian, Mahdi Feizpour, Salvatore Leonardi Gianluca, Ali Mirzaei, and Anna Bonavita

Subjects
Materials science, Nanotechnology, 02 engineering and technology, 010402 general chemistry, 021001 nanoscience & nanotechnology, 01 natural sciences, gas sensor, 0104 chemical sciences, lcsh:TP785-869, lcsh:Clay industries. Ceramics. Glass, electrical resistance, Ceramics and Composites, Pechini sol-gel, Fe2O3, commercial powder, 0210 nano-technology, Nano sized
Abstract

In this work, Fe2O3 nanoparticles (NPs) were successfully synthesized by Pechini sol-gel method. Scanning electron microscopy, transmission electron microscopy and X-ray diffraction characterizations were used to study the morphology and crystal structure of the synthesized products. The electrical and gas sensing behaviour of the synthesized and commercial Fe2O3 samples, prepared in the form of thick films, were studied. Though the commercial Fe2O3 powders had lower resistance but it was found that the synthesized Fe2O3 NPs had better gas sensing properties. The underlying mechanisms are discussed in details. The present findings show advantages of Fe2O3 NPs over micro-size particles for gas sensing applications.

Published
2017

20. FO004CITRATE BUFFERS INCREASE DIALYSIS EFFICIENCY AND REDUCE BIOMARKERS OF INFLAMMATION, ENDOTHELIAL DYSFUNCTION AND VASCULAR CALCIFICATION: A MONOCENTRIC TRANSLATIONAL STUDY

Author

Dellepiane, Sergio, primary, Cantaluppi, Vincenzo, additional, Guarena, Cesare, additional, Medica, Davide, additional, Musso, Tiziana, additional, Leonardi, Gianluca, additional, Talaia, Marinella, additional, Gai, Massimo, additional, Anania, Patrizia, additional, and Biancone, Luigi, additional

Published
2015
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24. Assessment of Phasic Changes of Vascular Size by Automated Edge Tracking-State of the Art and Clinical Perspectives

Author

Luca Mesin, Stefano Albani, Piero Policastro, Paolo Pasquero, Massimo Porta, Chiara Melchiorri, Gianluca Leonardi, Carlo Albera, Paolo Scacciatella, Pierpaolo Pellicori, Davide Stolfo, Andrea Grillo, Bruno Fabris, Roberto Bini, Alberto Giannoni, Antonio Pepe, Leonardo Ermini, Stefano Seddone, Gianfranco Sinagra, Francesco Antonini-Canterin, Silvestro Roatta, Mesin, Luca, Albani, Stefano, Policastro, Piero, Pasquero, Paolo, Porta, Massimo, Melchiorri, Chiara, Leonardi, Gianluca, Albera, Carlo, Scacciatella, Paolo, Pellicori, Pierpaolo, Stolfo, Davide, Grillo, Andrea, Fabris, Bruno, Bini, Roberto, Giannoni, Alberto, Pepe, Antonio, Ermini, Leonardo, Seddone, Stefano, Sinagra, Gianfranco, Antonini-Canterin, Francesco, and Roatta, Silvestro

Subjects
arterial stiffness, fluid volume assessment, inferior vena cava, pulsatility, right atrial pressure, ultrasound imaging, RC666-701, arterial stiffne, Diseases of the circulatory (Cardiovascular) system, Review, Cardiovascular Medicine, Cardiology and Cardiovascular Medicine
Abstract

Assessment of vascular size and of its phasic changes by ultrasound is important for the management of many clinical conditions. For example, a dilated and stiff inferior vena cava reflects increased intravascular volume and identifies patients with heart failure at greater risk of an early death. However, lack of standardization and sub-optimal intra- and inter- operator reproducibility limit the use of these techniques. To overcome these limitations, we developed two image-processing algorithms that quantify phasic vascular deformation by tracking wall movements, either in long or in short axis. Prospective studies will verify the clinical applicability and utility of these methods in different settings, vessels and medical conditions.

Published
2022

25. [Efficacy of SUPRA HFR in the treatment of acute renal damage during multiple myeloma].

Author

Daidola G, Guarena C, Brustia M, Leonardi G, Vigotti FN, Marciello A, Bianco S, Chiarinotti D, Saltarelli M, Besso L, and Biancone L

Subjects
Acute Kidney Injury etiology, Aged, Antineoplastic Combined Chemotherapy Protocols therapeutic use, Combined Modality Therapy, Female, Humans, Immunoglobulin Light Chains metabolism, Male, Middle Aged, Multiple Myeloma drug therapy, Myeloma Proteins metabolism, Plasmapheresis, Treatment Outcome, Acute Kidney Injury therapy, Hemodiafiltration methods, Multiple Myeloma complications
Abstract

Acute Kidney Injury (AKI) is a frequent complication of multiple myeloma (MM) with unfavorable prognostic significance. Light chains removal, combined with hematological therapy (CT) seems to offer significant benefits to renal function recovery (RFR). The SUPRA HFR, through the combination of high cut-off membrane without albumin loss and adsorbent cartridge, represents one of the "emerging" light chain removal methods. We report our multicentric retrospective experience with SUPRA HFR in 7 MM patients. At the end of the treatment with SUPRA HFR a significant reduction in serum free light chains compared to baseline was observed (min 24%; max 90%; median 74%). Despite a not always early start of the treatment, all patients recovered renal function with withdrawal from dialysis in 6/7 cases. Our preliminary experience of a combination of SUPRA HFR treatment with CT in 7 MM patients with AKI showed a significative renale functional recovery, with favourable cost/benefit ratio and a simple treatment schedule. These encouraging data suggest to further extend such treatment option, waiting for larger studies in this field., (Copyright by Società Italiana di Nefrologia SIN, Rome, Italy.)

Published
2018

26. ["Getting to zero infections" in hemodialysis].

Author

Leonardi G, Finotto G, Talaia M, Nappo A, Dolla C, Di Vico MC, Diena D, Linsalata A, Guarena C, Barbaro S, and Biancone L

Subjects
Humans, Anti-Infective Agents, Local therapeutic use, Bandages, Catheter-Related Infections prevention & control, Chlorhexidine therapeutic use, Education, Nursing, Renal Dialysis
Abstract

Introduction: We describe two measures adopted in hemodialysis outpatient population in order to reduce Central Venous Catheter (CVC) related infections. The first is a nurse staff training in the field project and the second deals with the employment of chlorhexidine-impregnated dressing devices. These actions were performed after high infection rates were observed through a dedicated register., Materials and Methods: In the limited assistance dialysis center, direct observation (12/2012-02/2013) quantified the gap between the observed and expected health care behaviour. Training needs were defined and a 40 hours nurse staff training in the field was performed on two occasions. In the hospital dialysis center, we introduced alcoholic 2% chlorhexidine solution and chlorhexidine-impregnated dressing devices to the exit site (CHG-Tegaderm and BioPatch). Infections (cumulatively bacteremia/sepsis/skin exit/subcutaneous tunnel) were monitored continuously., Results: Infection rates at the two locations were progressively reduced, reaching a value of zero at the limited assistance center. Nurse staff training in the field produced: two patient reports and three CVC management protocols, Italian language translation of the "The 5 moments of dialysis" WHO poster, alcoholic 2% chlorhexidine adoption to exit-site medication and improvement of environment cleaning/sanitation actions., Conclusions: Our experience shows that continuously monitoring infection rates represents the first step for timely corrective action. The continuous updating of health personnel, codified prevention measures and an ongoing commitment to raise awareness in a routine practice, allows us to obtain the goal of "getting to zero infections". The staff training produced equal or superior results compared to the isolated use of new chlorhexidine-impregnated dressing devices.

Published
2015

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